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https://www.readbyqxmd.com/read/29773355/pain-assessment-and-management-by-nurses-in-a-geriatric-setting-discrepancies-between-guidelines-and-documented-practice
#1
Irit Shahar, Gad Mendelson, Shlomit Gerbi, Merav Ben Natan
Pain is a common subjective symptom among older adults in general and among older adult residents in long-term geriatric facilities in particular. Pain diminishes older adults' quality of life and may impair their ability to recover from various illnesses. Therefore, the Israeli Ministry of Health has issued guidelines on effectively assessing and treating pain in this population. To examine discrepancies between the Ministry of Health's pain assessment guidelines and documented practice by nursing staff at a long-term geriatric care facility and whether these discrepancies correlate to characteristics of the nurses, the wards, and the patients' characteristics...
May 14, 2018: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
https://www.readbyqxmd.com/read/29771217/cognitive-behavioral-therapy-mindfulness-and-hypnosis-as-treatment-methods-for-generalized-anxiety-disorder
#2
Carolyn Daitch
Individuals suffering from generalized anxiety disorder (GAD) experience a broad range of physical, emotional, and cognitive distress. A hallmark of GAD is anxiety around making decisions. Many clinicians notice improvements in patients through specific modalities, such as mindfulness, hypnosis, and cognitive behavioral therapy (CBT); however, these individual methods sometimes fall short. Clinicians and researchers alike note that it can be more effective to combine these three methods into an integrative treatment protocol...
July 2018: American Journal of Clinical Hypnosis
https://www.readbyqxmd.com/read/29770081/increase-in-neisseria-meningitidis-serogroup-w-invasive-disease-in-canada-2009-2016
#3
Rsw Tsang, L Hoang, G J Tyrrell, G Horsman, P Van Caeseele, F Jamieson, B Lefebvre, D Haldane, R R Gad, G J German, G Zahariadis
No abstract text is available yet for this article.
July 6, 2017: Canada Communicable Disease Report, Relevé des Maladies Transmissibles Au Canada
https://www.readbyqxmd.com/read/29766044/filter-based-phase-shifts-distort-neuronal-timing-information
#4
Dorin Yael, Jacob J Vecht, Izhar Bar-Gad
Filters are widely used for the modulation, typically attenuation, of amplitudes of different frequencies within neurophysiological signals. Filters, however, also induce changes in the phases of different frequencies whose amplitude is unmodulated. These phase shifts cause time lags in the filtered signals, leading to a disruption of the timing information between different frequencies within the same signal and between different signals. The emerging time lags can be either constant in the case of linear phase (LP) filters or vary as a function of the frequency in the more common case of non-LP (NLP) filters...
March 2018: ENeuro
https://www.readbyqxmd.com/read/29759201/specific-detection-of-stable-single-nucleobase-mismatch-using-su-8-coated-silicon-nanowires-platform
#5
Melania Banu, Monica Simion, Marian C Popescu, Pericle Varasteanu, Mihaela Kusko, Ileana C Farcasanu
Novel microarray platform for single nucleotide polymorphisms (SNPs) detection has been developed using silicon nanowires (SiNWs) as support and two different surface modification methods for attaining the necessary functional groups. Accordingly, we compared the detection specificity and stability over time of the probes printed on SiNWs modified with (3-aminopropyl)triethoxysilane (APTES) and glutaraldehyde (GAD), or coated with a simpler procedure using epoxy-based SU-8 photoresist. Scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDX) were used for comparative characterization of the unmodified and coated SiNWs...
August 1, 2018: Talanta
https://www.readbyqxmd.com/read/29758471/the-predictive-specificity-of-psychological-vulnerability-markers-for-the-course-of-affective-disorders
#6
Sascha Y Struijs, Femke Lamers, Philip Spinhoven, Willem van der Does, Brenda W J H Penninx
High scores on markers of psychological vulnerability have been associated with a worse course of affective disorders. However, little is known about the specificity of those associations in predicting the course of different depressive and anxiety disorders. We examined the impact of psychological vulnerability on the short- and long-term course of depressive and anxiety disorders. Participants from the Netherlands Study of Depression and Anxiety with a current diagnosis of depression or anxiety (n = 1256) were reassessed after 2 and 6 years...
April 30, 2018: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29755190/venous-blood-gases-plasma-biochemistry-and-hematology-of-wild-caught-common-chameleons-chamaeleo-chamaeleon
#7
David Eshar, Melanie Ammersbach, Boaz Shacham, Gad Katzir, Hugues Beaufrère
The purpose of this study was to determine a wide range of selected hematologic, venous blood gases, and plasma biochemistry analytes in common chameleons (Chamaeleo chamaeleon) . Blood samples were collected from the ventral tail vein of 41 common chameleons to determine reference intervals for 30 different blood analytes. The calcium-to-phosphorus ratio, packed cell volume (PCV), refractometric total solids (TS), blood cell counts, and differentials were also determined. The microscopic evaluation of blood smears revealed inclusion bodies in monocytes in 7 of the samples...
April 2018: Canadian Journal of Veterinary Research, Revue Canadienne de Recherche Vétérinaire
https://www.readbyqxmd.com/read/29748350/prognostic-significance-of-creatinine-increases-during-an-acute-heart-failure-admission-in-patients-with-and-without-residual-congestion-a-post-hoc-analysis-of-the-protect-data
#8
Marco Metra, Gad Cotter, Stefanie Senger, Christopher Edwards, John G Cleland, Piotr Ponikowski, Guillermo C Cursack, Olga Milo, John R Teerlink, Michael M Givertz, Christopher M O'Connor, Howard C Dittrich, Daniel M Bloomfield, Adriaan A Voors, Beth A Davison
BACKGROUND: The importance of a serum creatinine increase, traditionally considered worsening renal function (WRF), during admission for acute heart failure has been recently debated, with data suggesting an interaction between congestion and creatinine changes. METHODS AND RESULTS: In post hoc analyses, we analyzed the association of WRF with length of hospital stay, 30-day death or cardiovascular/renal readmission and 90-day mortality in the PROTECT study (Placebo-Controlled Randomized Study of the Selective A1 Adenosine Receptor Antagonist Rolofylline for Patients Hospitalized With Acute Decompensated Heart Failure and Volume Overload to Assess Treatment Effect on Congestion and Renal Function)...
May 2018: Circulation. Heart Failure
https://www.readbyqxmd.com/read/29747614/there-is-more-to-mental-illness-than-negative-affect-comprehensive-temperament-profiles-in-depression-and-generalized-anxiety
#9
Irina Trofimova, William Sulis
BACKGROUND: Temperament and mental illness are thought to represent varying degrees along the same continuum of neurotransmitter imbalances. A taxonomy of temperament could provide the basis for a new taxonomy of mental illness. Most popular models of temperament, being based heavily on emotionality traits, show very poor ability to discriminate between mental disorders. The main goal of this study was to examine whether a temperament model based on modern neurophysiology and possessing an extensive set of non-emotionality traits provides better discrimination between Major Depression (MD), Generalized Anxiety (GAD) and Comorbid MD and GAD, in comparison to emotionality-based temperament models...
May 10, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29747135/generalized-anxiety-disorder-and-associated-factors-in-adults-in-the-amazon-brazil-a-population-based-study
#10
Marcus T Silva, Mónica Caicedo Roa, Silvia S Martins, Andréa Tenório Correia da Silva, Tais F Galvao
BACKGROUND: The purpose of this study was to assess the prevalence and associated factors of generalized anxiety disorder (GAD) in adults using the seven-item GAD scale (GAD-7) and to evaluate the properties of the two-item (GAD-2) as a population screening tool. METHODS: We carried out a cross-sectional population-based study in the Manaus Metropolitan Region in 2015, Brazil. Adults aged 18 years or more were eligible to participate. We performed probabilistic three-phase sampling and collected sociodemographic and clinical variables...
April 22, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29745910/misdiagnosed-patient-with-latent-autoimmune-diabetes-in-adults-case-report
#11
H Petreski
Latent Autoimmune Diabetes in Adults (LADA) is often misdiagnosed because it lacks both awareness and standardized diagnostic criteria. A 30-year-old patient with high blood glucose, HbA1c level 10.1% and positive GAD antibodies was diagnosed with type 1 diabetes but LADA was not ruled out. Patient refused to receive insulin therapy. He chose to follow the dietary restrictions and therapy with sulfonylurea, initiated by another physician. Following 7 months the patient's HbA1c values decreased, but never achieved the goal...
April 2018: Georgian Medical News
https://www.readbyqxmd.com/read/29744618/association-between-central-venous-pressure-as-assessed-by-echocardiography-left-ventricular-function-and-acute-cardio-renal-syndrome-in-patients-with-st-segment-elevation-myocardial-infarction
#12
Shafik Khoury, Arie Steinvil, Amir Gal-Oz, Gilad Margolis, Aviram Hochstatd, Yan Topilsky, Gad Keren, Yacov Shacham
BACKGROUND: Recent reports have demonstrated the adverse effects of venous congestion on renal function in patients with heart failure. None of these trials, however, has evaluated the effect of acute myocardial ischemia on the occurrence of acute kidney injury (AKI). METHODS: We conducted a retrospective study of 1336 ST segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) between June 2012 and June 2016...
May 9, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29739481/ventromedial-prefrontal-cortex-activity-and-pathological-worry-in-generalised-anxiety-disorder
#13
E Via, M A Fullana, X Goldberg, D Tinoco-González, I Martínez-Zalacaín, C Soriano-Mas, C G Davey, J M Menchón, B Straube, T Kircher, J Pujol, N Cardoner, B J Harrison
BACKGROUND: Pathological worry is a hallmark feature of generalised anxiety disorder (GAD), associated with dysfunctional emotional processing. The ventromedial prefrontal cortex (vmPFC) is involved in the regulation of such processes, but the link between vmPFC emotional responses and pathological v. adaptive worry has not yet been examined.AimsTo study the association between worry and vmPFC activity evoked by the processing of learned safety and threat signals. METHOD: In total, 27 unmedicated patients with GAD and 56 healthy controls (HC) underwent a differential fear conditioning paradigm during functional magnetic resonance imaging...
May 9, 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29738952/changing-patterns-in-the-prevalence-of-posttraumatic-stress-disorder-major-depressive-episode-and-generalized-anxiety-disorder-over-24-months-following-a-road-traffic-crash-results-from-the-uq-support-study
#14
Justin Kenardy, Shannon L Edmed, Swati Shourie, Jacelle Warren, Anna Crothers, Erin A Brown, Cate M Cameron, Michelle Heron-Delaney
OBJECTIVE: To examine the prevalence and changing patterns of PTSD, major depressive episode (MDE), and generalized anxiety disorder (GAD) in adult claimants who sustained a non-catastrophic injury in a road traffic crash (RTC) in Queensland, Australia. METHOD: Participants (N = 284) were assessed at approximately 6, 12, and 24 months post-RTC using the composite international diagnostic interview (CIDI) modules for PTSD, and CIDI-short form for MDE, and GAD...
April 21, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29738944/sex-differences-in-traumatic-events-and-psychiatric-morbidity-associated-to-probable-posttraumatic-stress-disorder-among-latino-prisoners
#15
Coralee Pérez-Pedrogo, Alfonso Martínez-Taboas, Rafael A González, José N Caraballo, Carmen E Albizu-García
Latinos comprised 17.1% of the U.S. population and 33.1% of US prisoners, yet they are underrepresented in the psychopathology literature. Despite higher rates of trauma among incarcerated individuals than in the general population, most of the previous research in this area focused primarily on women samples, and very few studies examined sex differences in PTSD and traumatic experiences. In addition, there is a need for research assessing traumatic experiences and probable PTSD in men and women Latino inmates to inform culturally competent care and sex sensitive care for this vulnerable and underserved population...
April 14, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29738424/effects-of-vaginal-estradiol-tablets-and-moisturizer-on-menopause-specific-quality-of-life-and-mood-in-healthy-postmenopausal-women-with-vaginal-symptoms-a-randomized-clinical-trial
#16
Susan J Diem, Katherine A Guthrie, Caroline M Mitchell, Susan D Reed, Joseph C Larson, Kristine E Ensrud, Andrea Z LaCroix
OBJECTIVE: Compare the effects of a vaginal estradiol tablet and a vaginal moisturizer, each to placebo, on menopause-related quality of life and mood in postmenopausal women with moderate-severe vulvovaginal symptoms. METHODS: A total of 302 postmenopausal women enrolled in a 12-week, double-blind, placebo-controlled randomized trial were assigned to vaginal 10 μg estradiol tablet plus placebo gel (n = 102), vaginal moisturizer plus placebo tablet (n = 100), or dual placebo (n = 100)...
May 7, 2018: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29736827/generalized-anxiety-disorder-gad-and-comorbid-major-depression-with-gad-are-characterized-by-enhanced-nitro-oxidative-stress-increased-lipid-peroxidation-and-lowered-lipid-associated-antioxidant-defenses
#17
Michael Maes, Kamila Landucci Bonifacio, Nayara Rampazzo Morelli, Heber Odebrecht Vargas, Estefânia Gastaldello Moreira, Drozdstoy St Stoyanov, Décio Sabbatini Barbosa, André F Carvalho, Sandra Odebrecht Vargas Nunes
Accumulating evidence shows that nitro-oxidative pathways play an important role in the pathophysiology of major depressive disorder (MDD) and bipolar disorder (BD) and maybe anxiety disorders. The current study aims to examine superoxide dismutase (SOD1), catalase, lipid hydroperoxides (LOOH), nitric oxide metabolites (NOx), advanced oxidation protein products (AOPP), malondialdehyde (MDA), glutathione (GSH), paraoxonase 1 (PON1), high-density lipoprotein cholesterol (HDL), and uric acid (UA) in participants with and without generalized anxiety disorder (GAD) co-occurring or not with BD, MDD, or tobacco use disorder...
May 7, 2018: Neurotoxicity Research
https://www.readbyqxmd.com/read/29736130/applicability-evaluation-of-simplified-cognitive-behavioral-therapy
#18
Li Zhang, Zhipei Zhu, Fang Fang, Yuan Shen, Na Liu, Chunbo Li
Background: We have developed a structured cognitive behavioral therapy manual for anxiety disorder in China, and the present study evaluated the applicability of simplified cognitive behavioral therapy based on our previous research. Aims: To evaluate the applicability of simplified cognitive behavioral therapy (SCBT) on generalized anxiety disorder (GAD) by conducting a multi-center controlled clinical trial. Methods: A multi-center controlled clinical trial of SCBT was conducted on patients with GAD, including institutions specializing in mental health and psychiatry units in general hospitals...
April 25, 2018: Shanghai Archives of Psychiatry
https://www.readbyqxmd.com/read/29732161/rapid-onset-diabetic-ketoacidosis-secondary-to-nivolumab-therapy
#19
Senhong Lee, Aparna Morgan, Sonali Shah, Peter R Ebeling
We report a case of a 67-year-old man with type 2 diabetes presented with diabetic ketoacidosis, two weeks after his first dose of nivolumab therapy for non-small-cell lung carcinoma. He was started on empagliflozin two days prior in the setting of hyperglycaemia after the initiation of nivolumab therapy. Laboratory evaluation revealed an undetectable C-peptide and a positive anti-glutamic acid decarboxylase (GAD) antibody. He was treated with intravenous fluids and insulin infusion and was subsequently transitioned to subcutaneous insulin and discharged home...
2018: Endocrinology, Diabetes & Metabolism Case Reports
https://www.readbyqxmd.com/read/29731677/aucubin-promotes-differentiation-of-neural-precursor-cells-into-gabaergic-neurons
#20
Miyeoun Song, Hyomin Kim, Sujin Park, Hyockman Kwon, Insil Joung, Yunhee Kim Kwon
Aucubin is a small compound naturally found in traditional medicinal herbs with primarily anti-inflammatory and protective effects. In the nervous system, aucubin is reported to be neuroprotective by enhancing neuronal survival and inhibiting apoptotic cell death in cultures and disease models. Our previous data, however, suggest that aucubin facilitates neurite elongation in cultured hippocampal neurons and axonal regrowth in regenerating sciatic nerves. Here, we investigated whether aucubin facilitates the differentiation of neural precursor cells (NPCs) into specific types of neurons...
April 2018: Experimental Neurobiology
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