keyword
https://read.qxmd.com/read/36927072/computational-modeling-of-the-chlamydial-developmental-cycle-reveals-a-potential-role-for-asymmetric-division
#21
JOURNAL ARTICLE
Travis J Chiarelli, Nicole A Grieshaber, Cody Appa, Scott S Grieshaber
Chlamydia trachomatis is an obligate intracellular bacterium that progresses through an essential multicell form developmental cycle. Infection of the host is initiated by the elementary body (EB). Once in the host, the EB cell differentiates into the noninfectious, but replication-competent, reticulate body, or RB. After multiple rounds of replication, RBs undergo secondary differentiation, eventually producing newly infectious EBs. Here, we generated paired cell-type promoter reporter constructs and determined the kinetics of the activities of the euo , hctA , and hctB promoters...
March 16, 2023: MSystems
https://read.qxmd.com/read/36919394/dowling-degos-disease-in-the-anogenital-region
#22
JOURNAL ARTICLE
Marko Belamarić, Suzana Ljubojević Hadžavdić
Dowling-Degos disease (DDD) is a benign, rare genodermatosis (reticulate pigmented anomaly) of flexure sites with autosomal dominant inheritance (1,2).The disease is caused by a loss-of-function mutation of keratin 5 (KRT5) present on the chromosome 12q gene (3). It usually affects the younger population, most commonly 20-30 years of age, with some patients being older and with a predominance in the female population (4). The disease is characterized by formation of dark, hyperpigmented macules which are confined to the flexure sites, most commonly over the axillae, groin area, and neck, along with scattered, comedo-like lesions and pitted acneiform scars (3,5)...
December 2022: Acta Dermatovenerologica Croatica: ADC
https://read.qxmd.com/read/36917122/coordinatively-cross-linked-binders-for-silicon-based-electrodes-for-li-ion-batteries-beneficial-impact-on-mechanical-properties-and-electrochemical-performance
#23
JOURNAL ARTICLE
Lucas Huet, Driss Mazouzi, Philippe Moreau, Nicolas Dupré, Michael Paris, Sébastien Mittelette, Danielle Laurencin, Thomas Devic, Lionel Roué, Bernard Lestriez
A simple and versatile preparation of Zn(II)-poly(carboxylates) reticulated binders by the addition of Zn(II) precursors (ZnSO4 , ZnO, or Zn(NO3 )2 ) into a preoptimized poly(carboxylic acids) binder solution is proposed. These binders lead systematically to a significantly improved electrochemical performance when used for the formulation of silicon-based negative electrodes. The formation of carboxylate-Zn(II) coordination bonds formation is investigated by rheology and FTIR and NMR spectroscopies. Mechanical characterizations reveal that the coordinated binder offers a better electrode coating cohesion and adhesion to the current collector, as well as higher hardness and elastic modulus, which are even preserved in the presence of a carbonate solvent (i...
March 14, 2023: ACS Applied Materials & Interfaces
https://read.qxmd.com/read/36881620/tsks-localizes-to-nuage-in-spermatids-and-regulates-cytoplasmic-elimination-during-spermiation
#24
JOURNAL ARTICLE
Keisuke Shimada, Soojin Park, Seiya Oura, Taichi Noda, Akane Morohoshi, Martin M Matzuk, Masahito Ikawa
Spermatozoa have a streamlined shape to swim through the oviduct to fertilize oocytes. To become svelte spermatozoa, spermatid cytoplasm must be eliminated in several steps including sperm release, which is part of spermiation. Although this process has been well observed, the molecular mechanisms that underlie it remain unclear. In male germ cells, there are membraneless organelles called nuage, which are observed by electron microscopy in various forms of dense material. Reticulated body (RB) and chromatoid body remnant (CR) are two types of nuage in spermatids, but the functions of both are unknown...
March 14, 2023: Proceedings of the National Academy of Sciences of the United States of America
https://read.qxmd.com/read/36842731/phylogenomic-analyses-of-camellia-support-reticulate-evolution-among-major-clades
#25
JOURNAL ARTICLE
Ting Zan, Yi-Tao He, Min Zhang, Takahiro Yonezawa, Hong Ma, Qiangmin Zhao, Wenyu Kuo, Wen-Ju Zhang, Chien-Hsun Huang
Camellia (Theaceae) is a morphologically highly diverse genus of flowering plants and includes many famous species with high economic value, and the phylogeny of this genus is not fully resolved. We used 98 transcriptomes from 90 Camellia species and identified 1481 low-copy genes to conduct a detailed analysis of the phylogeny of this genus according to various data-screening criteria. The results show that, very different from the two existing classification systems of Camellia, 90 species are grouped into 8 main clades and two independent species, and that all 8 clades except Clade 8 were strongly supported by almost all the coalescent or concatenated trees using different gene subsets...
February 24, 2023: Molecular Phylogenetics and Evolution
https://read.qxmd.com/read/36688253/record-ultralarge-pores-low-density-three-dimensional-covalent-organic-framework-for-controlled-drug-delivery
#26
JOURNAL ARTICLE
Yu Zhao, Saikat Das, Taishu Sekine, Haruna Mabuchi, Tsukasa Irie, Jin Sakai, Dan Wen, Weidong Zhu, Teng Ben, Yuichi Negishi
The unique structural characteristics of three-dimensional (3D) covalent organic frameworks (COFs) like high surface areas, interconnected pore system and readily accessible active sites render them promising platforms for a wide set of functional applications. Albeit promising, the reticular construction of 3D COFs with large pores is a very demanding task owing to the formation of interpenetrated frameworks. Herein we report the designed synthesis of a 3D non-interpenetrated stp net COF, namely TUS-64, with the largest pore size of all 3D COFs (47 Å) and record-low density (0...
January 23, 2023: Angewandte Chemie
https://read.qxmd.com/read/36622169/comparison-of-rhizospheric-and-endophytic-bacterial-compositions-between-netted-and-oriental-melons
#27
JOURNAL ARTICLE
Jian Xiao, Yan Sun, Yi He, Xiaofu Tang, Shangdong Yang, Jinyan Huang
To elucidate the biological mechanism of formation of the netted pattern in melons, the characteristics of the soil bacterial community structure in the rhizosphere and of the endophytic bacteria in the stems of netted melons were analyzed. High-throughput sequencing technology was used for the analysis of plant stem and soil samples collected from netted melons (NM) and oriental melons (OM). At the phylum level, Acidobacteria, Dependentiae, and Chloroflexi were the dominant endophytic bacteria in the stems of NM only...
January 9, 2023: Microbiology Spectrum
https://read.qxmd.com/read/36462131/characterization-of-the-multiple-domains-of-pex30-involved-in-subcellular-localization-of-the-protein-and-regulation-of-peroxisome-number
#28
JOURNAL ARTICLE
Nayan Moni Deori, Terence Infant, Rajkumar P Thummer, Shirisha Nagotu
Pex30 is a peroxisomal protein whose role in peroxisome biogenesis via the endoplasmic reticulum has been established. It is a 58 KDa multi-domain protein that facilitates contact site formation between various organelles. The present study aimed to investigate the role of various domains of the protein in its sub-cellular localization and regulation of peroxisome number. For this, we created six truncations of the protein (1-87, 1-250, 1-352, 88-523, 251-523 and 353-523) and tagged GFP at the C-terminus. Biochemical methods and fluorescence microscopy were used to characterize the effect of truncation on expression and localization of the protein...
December 3, 2022: Cell Biochemistry and Biophysics
https://read.qxmd.com/read/36272416/neutrophil-plucking-on-megakaryocytes-drives-platelet-production-and-boosts-cardiovascular-disease
#29
JOURNAL ARTICLE
Tobias Petzold, Zhe Zhang, Iván Ballesteros, Inas Saleh, Amin Polzin, Manuela Thienel, Lulu Liu, Qurrat Ul Ain, Vincent Ehreiser, Christian Weber, Badr Kilani, Pontus Mertsch, Jeremias Götschke, Sophie Cremer, Wenwen Fu, Michael Lorenz, Hellen Ishikawa-Ankerhold, Elisabeth Raatz, Shaza El-Nemr, Agnes Görlach, Esther Marhuenda, Konstantin Stark, Joachim Pircher, David Stegner, Christian Gieger, Marc Schmidt-Supprian, Florian Gaertner, Isaac Almendros, Malte Kelm, Christian Schulz, Andrés Hidalgo, Steffen Massberg
Intravascular neutrophils and platelets collaborate in maintaining host integrity, but their interaction can also trigger thrombotic complications. We report here that cooperation between neutrophil and platelet lineages extends to the earliest stages of platelet formation by megakaryocytes in the bone marrow. Using intravital microscopy, we show that neutrophils "plucked" intravascular megakaryocyte extensions, termed proplatelets, to control platelet production. Following CXCR4-CXCL12-dependent migration towards perisinusoidal megakaryocytes, plucking neutrophils actively pulled on proplatelets and triggered myosin light chain and extracellular-signal-regulated kinase activation through reactive oxygen species...
October 18, 2022: Immunity
https://read.qxmd.com/read/36219107/-chlamydia-trachomatis-cell-to-cell-spread-through-tunneling-nanotubes
#30
JOURNAL ARTICLE
Rico Jahnke, Svea Matthiesen, Luca M Zaeck, Stefan Finke, Michael R Knittler
Tunneling nanotubes (TNTs) are transient cellular connections that consist of dynamic membrane protrusions. They play an important role in cell-to-cell communication and mediate the intercellular exchanges of molecules and organelles. TNTs can form between different cell types and may contribute to the spread of pathogens by serving as cytoplasmic corridors. We demonstrate that Chlamydia ( C. ) trachomatis-infected human embryonic kidney (HEK) 293 cells and other cells form TNT-like structures through which reticulate bodies (RBs) pass into uninfected cells...
October 11, 2022: Microbiology Spectrum
https://read.qxmd.com/read/36205197/reticulate-evolution-underlies-synergistic-trait-formation-in-human-communities
#31
REVIEW
Nathalie Gontier, Anton Sukhoverkhov
This paper investigates how reticulate evolution contributes to a better understanding of human sociocultural evolution in general, and community formation in particular. Reticulate evolution is evolution as it occurs by means of symbiosis, symbiogenesis, lateral gene transfer, infective heredity, and hybridization. From these mechanisms and processes, we mainly zoom in on symbiosis and we investigate how it underlies the rise of (1) human, plant, animal, and machine interactions typical of agriculture, animal husbandry, farming, and industrialization; (2) diet-microbiome relationships; and (3) host-virome and other pathogen interactions that underlie human health and disease...
October 7, 2022: Evolutionary Anthropology
https://read.qxmd.com/read/36037520/temporal-in-vivo-platelet-labelling-in-mice-reveals-age-dependent-receptor-expression-and-conservation-of-specific-mrnas
#32
JOURNAL ARTICLE
Paul C Armstrong, Harriet E Allan, Nicholas S Kirkby, Clemens Gutmann, Abhishek Joshi, Marilena Crescente, Jane A Mitchell, Manuel Mayr, Timothy D Warner
The proportion of young platelets, also known as newly formed or reticulated, within the overall platelet population has been clinically correlated with adverse cardiovascular outcomes. Our understanding of this is incomplete, however, because of limitations in the technical approaches available to study platelets of different ages. In this study we have developed and validated an in vivo 'temporal labelling' approach using injectable fluorescent anti-platelet antibodies to sub-divide platelets by age and assess differences in functional and molecular characteristics...
August 29, 2022: Blood Advances
https://read.qxmd.com/read/36014568/electrochemical-characteristics-of-shewanella-loihica-pv-4-on-reticulated-vitreous-carbon-rvc-with-different-potentials-applied
#33
JOURNAL ARTICLE
Shixin Wang, Xiaoming Zhang, Enrico Marsili
The current output of an anodic bioelectrochemical system (BES) depends upon the extracellular electron transfer (EET) rate from electricigens to the electrodes. Thus, investigation of EET mechanisms between electricigens and solid electrodes is essential. Here, reticulated vitreous carbon (RVC) electrodes are used to increase the surface available for biofilm formation of the known electricigen Shewanella loihica PV-4, which is limited in conventional flat electrodes. S. loihica PV-4 utilizes flavin-mediated EET at potential lower than the outer membrane cytochromes (OMC), while at higher potential, both direct electron transfer (DET) and mediated electron transfer (MET) contribute to the current output...
August 21, 2022: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://read.qxmd.com/read/35973046/multicomponent-functionalized-hkust-1-analogues-assembled-via-reticulation-of-prefabricated-metal-organic-polyhedral-cavities
#34
JOURNAL ARTICLE
Akim Khobotov-Bakishev, Cornelia von Baeckmann, Borja Ortín-Rubio, Laura Hernández-López, Alba Cortés-Martínez, Jordi Martínez-Esaín, Felipe Gándara, Judith Juanhuix, Ana E Platero-Prats, Jordi Faraudo, Arnau Carné-Sánchez, Daniel Maspoch
Metal-organic frameworks (MOFs) assembled from multiple building blocks exhibit greater chemical complexity and superior functionality in practical applications. Herein, we report a new approach based on using prefabricated cavities to design isoreticular multicomponent MOFs from a known parent MOF. We demonstrate this concept with the formation of multicomponent HKUST-1 analogues, using a prefabricated cavity that comprises a cuboctahedral Rh(II) metal-organic polyhedron functionalized with 24 carboxylic acid groups...
August 16, 2022: Journal of the American Chemical Society
https://read.qxmd.com/read/35938973/establishment-of-an-allotetraploid-fern-species-lepisorus-yamaokae-seriz-between-two-highly-niche-differentiated-parental-species
#35
JOURNAL ARTICLE
Tao Fujiwara, Tsubasa Egashira, José Said Gutiérrez-Ortega, Kiyotaka Hori, Atsushi Ebihara, Yasuyuki Watano
PREMISE: The successful establishment of polyploid species is hypothesized to be promoted by niche differentiation from the parental species or by range shifts during climate oscillations. However, few studies have considered both of these factors simultaneously. We resolved the origin of a tetraploid fern, Lepisorus yamaokae, and explored a pattern of niche differentiation among the allotetraploid and parental species in past and current climates. METHODS: We reconstructed phylogenetic trees based on plastid marker and single-copy nuclear genes to resolve the allopolyploid origin of L...
September 2022: American Journal of Botany
https://read.qxmd.com/read/35835404/transcriptome-analyses-reveal-the-potential-mechanisms-for-color-changes-of-a-sweet-orange-peel-induced-by-candidatus-liberibacter-asiaticus
#36
JOURNAL ARTICLE
Li Yuning, Yang Xianmei, Zhang Jingjing, Dai Jinghua, Liu Luyang, Lin Jintian, Shu Benshui
'Shatangju' mandarin (Citrus reticulate Blanco cv. Shatangju) is a Chinese citrus specialty in southern China with a delicious taste and an attractive appearance. Huanglongbing (HLB) caused by Candidatus Liberibacter asiaticus (CLas) threatens the Shatangju industry seriously. Fruits from citrus trees with HLB show 'red nose' peels with a serious reduction in fruit value. Differentially expressed genes (DEGs) have been identified in the leaves of several citrus species with HLB infection. However, similar studies on the fruit peels of citrus trees with HLB infection are very limited...
July 11, 2022: Gene
https://read.qxmd.com/read/35806722/gel-evolution-of-copper-tailing-based-green-geopolymers-in-marine-related-environments
#37
JOURNAL ARTICLE
Jing Li, Lang Yang, Feng Rao, Xiang Tian
Geopolymers have attracted extensive attention in the marine environment because of its special reticulate nanostructure. Gel evolutions of copper tailing-based green geopolymers were studied under air, deionized water, seawater, freeze-thaw cycle and carbonization environments. Their mechanical properties and microstructures were characterized by compressive strength measurement, X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), nuclear magnetic resonance (NMR) and scanning electron microscopy (SEM)...
June 30, 2022: Materials
https://read.qxmd.com/read/35783934/reticulate-evolution-in-the-western-mediterranean-mountain-ranges-the-case-of-the-leucanthemopsis-polyploid-complex
#38
JOURNAL ARTICLE
Salvatore Tomasello, Christoph Oberprieler
Polyploidization is one of the most common speciation mechanisms in plants. This is particularly relevant in high mountain environments and/or in areas heavily affected by climatic oscillations. Although the role of polyploidy and the temporal and geographical frameworks of polyploidization have been intensively investigated in the alpine regions of the temperate and arctic biomes, fewer studies are available with a specific focus on the Mediterranean region. Leucanthemopsis (Asteraceae) consists of six to ten species with several infraspecific entities, mainly distributed in the western Mediterranean Basin...
2022: Frontiers in Plant Science
https://read.qxmd.com/read/35774810/hydroxyproline-o-galactosyltransferases-synthesizing-type-ii-arabinogalactans-are-essential-for-male-gametophytic-development-in-arabidopsis
#39
JOURNAL ARTICLE
Dasmeet Kaur, Diana Moreira, Sílvia Coimbra, Allan M Showalter
In flowering plants, male reproductive function is determined by successful development and performance of stamens, pollen grains, and pollen tubes. Despite the crucial role of highly glycosylated arabinogalactan-proteins (AGPs) in male gamete formation, pollen grain, and pollen tube cell walls, the underlying mechanisms defining these functions of AGPs have remained elusive. Eight partially redundant Hyp-galactosyltransferases (named GALT2-GALT9) genes/enzymes are known to initiate Hyp- O -galactosylation for Hyp-arabinogalactan (AG) production in Arabidopsis thaliana ...
2022: Frontiers in Plant Science
https://read.qxmd.com/read/35713506/netrax-accurate-and-fast-maximum-likelihood-phylogenetic-network-inference
#40
JOURNAL ARTICLE
Sarah Lutteropp, Céline Scornavacca, Alexey M Kozlov, Benoit Morel, Alexandros Stamatakis
MOTIVATION: Phylogenetic networks can represent non-treelike evolutionary scenarios. Current, actively developed approaches for phylogenetic network inference jointly account for non-treelike evolution and incomplete lineage sorting. Unfortunately, this induces a very high computational complexity and current tools can only analyze small data sets. RESULTS: We present NetRAX, a tool for maximum likelihood inference of phylogenetic networks in the absence of incomplete lineage sorting...
June 17, 2022: Bioinformatics
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