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Reticulated Formation

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https://www.readbyqxmd.com/read/29666579/d-dencichine-regulates-thrombopoiesis-by-promoting-megakaryocyte-adhesion-migration-and-proplatelet-formation
#1
Shilan Ding, Min Wang, Song Fang, Huibo Xu, Huiting Fan, Yu Tian, Yadong Zhai, Shan Lu, Xin Qi, Fei Wei, Guibo Sun, Xiaobo Sun
Life-threatening chemotherapy-induced thrombocytopenia can increase the risk of bleeding due to a dramatic low platelet count, which may limit or delay treatment schedules in cancer patients. The pressing need for the rapid alleviation of the symptoms of thrombocytopenia has prompted us to search for novel highly effective and safe thrombopoietic agents. Pharmacological investigations have indicated that dencichine can prevent and treat blood loss and increase the number of platelets. On the basis of the neurotoxicity of dencichine, D-dencichine is artificially synthesized in the laboratory...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29617560/3d-anionic-silicate-covalent-organic-framework-with-srs-topology
#2
Oussama Yahiaoui, Andrew N Fitch, Frank Hoffmann, Michael Fröba, Arne Thomas, Jerome Roeser
The synthesis of 3D covalent organic frameworks (COFs) adopting novel topologies is challenging and so far 3D COFs were only reported for nets based on building blocks with tetrahedral geometry. We demonstrate the targeted synthesis of an anionic 3D COF crystallizing in the three-coordinated srs net by exploiting a recently developed linkage for the formation of anionic silicate COFs based on hypercoordinate silicon nodes. The framework, named SiCOF-5, was synthesized by reticulating dianionic hexacoordinate [SiO6]2- nodes with triangular triphenylene building blocks and adopts a two-fold interpenetrated srs-c net with an overall composition of Na2[Si(C18H6O6)] (where C18H6O6 is triphenylene-2,3,6,7,10,11-hexakis(olate))...
April 4, 2018: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29584421/benzoxazole-linked-ultrastable-covalent-organic-frameworks-for-photocatalysis
#3
Pi-Feng Wei, Ming-Zhu Qi, Zhi-Peng Wang, San-Yuan Ding, Wei Yu, Qiang Liu, Li-Ke Wang, Huai-Zhen Wang, Wan-Kai An, Wei Wang
The structural uniqueness of covalent organic frameworks (COFs) has brought these new materials great potential for advanced applications. One of the key aspects yet to be developed is how to improve the robustness of covalently linked reticular frameworks. In order to make the best use of π-conjugated structures, we develop herein a "killing two birds with one stone" strategy and construct a series of ultrastable benzoxazole-based COFs (denoted as LZU-190, LZU-191, and LZU-192) as metal-free photocatalysts...
March 27, 2018: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29562303/dating-the-species-network-allopolyploidy-and-repetitive-dna-evolution-in-american-daisies-melampodium-sect-melampodium-asteraceae
#4
Jamie McCann, Tae-Soo Jang, Jiri Macas, Gerald M Schneeweiss, Nicholas J Matzke, Petr Novák, Tod F Stuessy, José L Villaseñor, Hanna Weiss-Schneeweiss
Allopolyploidy has played an important role in the evolution of the flowering plants. Genome mergers are often accompanied by significant and rapid alterations of genome size and structure via chromosomal rearrangements and altered dynamics of tandem and dispersed repetitive DNA families. Recent developments in sequencing technologies and bioinformatic methods allow for a comprehensive investigation of the repetitive component of plant genomes. Interpretation of evolutionary dynamics following allopolyploidization requires both the knowledge of parentage and the age of origin of an allopolyploid...
March 19, 2018: Systematic Biology
https://www.readbyqxmd.com/read/29530649/metaplastic-woven-bone-in-bone-metastases-a-fourier-transform-infrared-analysis-and-imaging-of-bone-quality-ftir
#5
D Chappard, G Mabilleau, C Masson, A Tahla, E Legrand
Most osteolytic tumors are in fact mixed and contain an osteoblastic component associated with the predominant osteolytic areas. This metaplastic woven bone is always evidenced by histological analysis even in the absence of radiological expression. Metaplastic bone formation reflects the activation of new osteoblasts coming from the stimulation of the dormant lining cells. Twelve patients with secondary metastases of the iliac crest evidenced by hot spots on a99 Tc-MBP san were diagnosed by histomorphometry on bone biopsies...
March 9, 2018: Morphologie: Bulletin de L'Association des Anatomistes
https://www.readbyqxmd.com/read/29514307/inferring-phylogenetic-networks-using-phylonet
#6
Dingqiao Wen, Yun Yu, Jiafan Zhu, Luay Nakhleh
PhyloNet was released in 2008 as a software package for representing and analyzing phylogenetic networks. At the time of its release, the main functionalities in PhyloNet consisted of measures for comparing network topologies and a single heuristic for reconciling gene trees with a species tree. Since then, PhyloNet has grown significantly. The software package now includes a wide array of methods for inferring phylogenetic networks from data sets of unlinked loci while accounting for both reticulation (e.g...
March 5, 2018: Systematic Biology
https://www.readbyqxmd.com/read/29384268/dating-phototropic-microbial-lineages-with-reticulate-gene-histories
#7
C Magnabosco, K R Moore, J M Wolfe, G P Fournier
Phototrophic bacteria are among the most biogeochemically significant organisms on Earth and are physiologically related through the use of reaction centers to collect photons for energy metabolism. However, the major phototrophic lineages are not closely related to one another in bacterial phylogeny, and the origins of their respective photosynthetic machinery remain obscured by time and low sequence similarity. To better understand the co-evolution of Cyanobacteria and other ancient anoxygenic phototrophic lineages with respect to geologic time, we designed and implemented a variety of molecular clocks that use horizontal gene transfer (HGT) as additional, relative constraints...
January 31, 2018: Geobiology
https://www.readbyqxmd.com/read/29377394/platelet-predominate-gene-expression-and-reticulated-platelets-in-non-valvular-atrial-fibrillation-effect-of-pulmonary-veins-isolation
#8
Waldemar E Wysokinski, Alfonso Tafur, Yanhong Wu, Naser Ammash, Samuel J Asirvatham, Izabela Gosk-Bierska, Diane E Grill, Joshua P Slusser, Jozef Mruk, Robert D McBane
INTRODUCTION: Reticulated platelet (RP) content is increased in non-valvular atrial fibrillation (NVAF). The purpose of this study was to determine if platelet content, morphology and RP proportion are modulated by platelet genes. METHODS AND RESULTS: Expression of 6 platelet-predominate genes impacting platelet formation and release, platelet count and RP content were assessed in NVAF patients before and 3-4 months after pulmonary veins isolation (PVI) and compared to normal sinus rhythm (NSR) controls...
January 29, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29259611/a-structurally-specialized-uniform-wall-layer-is-essential-for-constructing-wall-ingrowth-papillae-in-transfer-cells
#9
Xue Xia, Hui-Ming Zhang, Christina E Offler, John W Patrick
Transfer cells are characterized by wall labyrinths with either a flange or reticulate architecture. A literature survey established that reticulate wall ingrowth papillae ubiquitously arise from a modified component of their wall labyrinth, termed the uniform wall layer; a structure absent from flange transfer cells. This finding sparked an investigation of the deposition characteristics and role of the uniform wall layer using a Vicia faba cotyledon culture system. On transfer of cotyledons to culture, their adaxial epidermal cells spontaneously trans -differentiate to a reticulate architecture comparable to their abaxial epidermal transfer cell counterparts formed in planta ...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29194636/benthic-flattened-cells-of-the-phylogenetically-related-marine-dinoflagellates-protoceratium-reticulatum-and-ceratocorys-mariaovidiorum-gonyaulacales-a-new-type-of-cyst
#10
Pablo Salgado, Santiago Fraga, Francisco Rodríguez, Isabel Bravo
A planktonic-benthic relationship has been described for many dinoflagellate species as part of their ecological strategy to overcome highly variable aquatic environments. Here, the phylogenetically and morphologically related marine dinoflagellates Protoceratium reticulatum and Ceratocorys mariaovidiorum were studied in relation to an unknown benthic life form. In vivo and fixed samples from cultures were analyzed in detail by light and scanning electron microscopy. In both species, a cell type with a morphology different from that of vegetative cells was observed in cultures grown until stationary phase...
February 2018: Journal of Phycology
https://www.readbyqxmd.com/read/28864250/a-straightforward-approach-to-enhance-the-textural-mechanical-and-biological-properties-of-injectable-calcium-phosphate-apatitic-cements-cpcs-cpc-blood-composites-a-comprehensive-study
#11
Charlotte Mellier, François-Xavier Lefèvre, Franck Fayon, Valérie Montouillout, Christelle Despas, Myriam Le Ferrec, Florian Boukhechba, Alain Walcarius, Pascal Janvier, Maeva Dutilleul, Olivier Gauthier, Jean-Michel Bouler, Bruno Bujoli
Two commercial formulations of apatitic calcium phosphate cements (CPCs), Graftys® Quickset (QS) and Graftys® HBS (HBS), similar in composition but with different initial setting time (7 and 15min, respectively), were combined to ovine whole blood. Surprisingly, although a very cohesive paste was obtained after a few minutes, the setting time of the HBS/blood composite dramatically delayed when compared to its QS analogue and the two blood-free references. Using solid state NMR, scanning electron microscopy and high frequency impedance measurements, it was shown that, in the particular case of the HBS/blood composite, formation of a reticulated and porous organic network occurred in the intergranular space, prior to the precipitation of apatite crystals driven by the cement setting process...
August 30, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28835360/chlamydia-trachomatis-the-persistent-pathogen
#12
REVIEW
Steven S Witkin, Evelyn Minis, Aikaterini Athanasiou, Julie Leizer, Iara M Linhares
Chlamydia trachomatis is an obligate intracellular bacterium whose only natural host is humans. Although presenting as asymptomatic in most women, genital tract chlamydial infections are a leading cause of pelvic inflammatory disease, tubal factor infertility, and ectopic pregnancy. C. trachomatis has evolved successful mechanisms to avoid destruction by autophagy and the host immune system and persist within host epithelial cells. The intracellular form of this organism, the reticulate body, can enter into a persistent nonreplicative but viable state under unfavorable conditions...
October 2017: Clinical and Vaccine Immunology: CVI
https://www.readbyqxmd.com/read/28813684/mimicking-mechanical-response-of-natural-tissues-strain-hardening-induced-by-transient-reticulation-in-lactose-modified-chitosan-chitlac
#13
Michela Cok, Pasquale Sacco, Davide Porrelli, Andrea Travan, Massimiliano Borgogna, Eleonora Marsich, Sergio Paoletti, Ivan Donati
The effect of transient cross-links has been explored on a lactose-modified chitosan, which previously had shown interesting biological features. The presence of galactose side chains and of the polyol spacer resulted particularly appealing for the reticulation by borate ions. The interaction between chitlac and borax was investigated by means of11 B NMR while rheology pointed to a marked non-linear behavior depending on the amount of borax added to the system. The presence of limited amount of cross-linking ion led to dilatant behavior when the steady flow curve was measured...
January 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28782926/mesoporous-polymer-frameworks-from-end-reactive-bottlebrush-copolymers
#14
Esra Altay, Dmytro Nykypanchuk, Javid Rzayev
Reticulated nanoporous materials generated by versatile molecular framework approaches are limited to pore dimensions on the scale of the utilized rigid molecular building blocks (<5 nm). The inherent flexibility of linear polymers precludes their utilization as long framework connectors for the extension of this strategy to larger length scales. We report a method for the fabrication of mesoporous frameworks by using bottlebrush copolymers with reactive end blocks serving as rigid macromolecular interconnectors with directional reactivity...
August 22, 2017: ACS Nano
https://www.readbyqxmd.com/read/28749260/pigmented-villonodular-synovitis-in-a-reticulated-giraffe-giraffa-camelopardalis
#15
Elizabeth A Ihms, Anne Rivas, Ellen Bronson, Lisa M Mangus
: A 17-yr-old, female, captive-born reticulated giraffe ( Giraffa camelopardalis ) presented with acute-onset lameness of the right metacarpophalangeal (fetlock) joint. Despite multiple courses of treatment, the lameness and swelling progressively worsened over a 3.5-yr period, and the giraffe was euthanized. At necropsy, gross and microscopic changes in the right, front fetlock and associated flexor tendon sheath included villous synovial hyperplasia and the formation of discrete pigmented nodules within synovial membranes...
June 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28723911/male-reproductive-system-and-spermatogenesis-of-limodromus-assimilis-paykull-1790
#16
Lea F Schubert, Stephanie Krüger, Gerald B Moritz, Veit Schubert
Based on advanced light and electron microscopy, we describe the male reproductive system and sperm development of Limodromus assimilis. The genital tract consists of pairs of uni-follicular testes, spermatic ducts with diverticula regions, seminal vesicles, accessory glands, an unpaired ejaculatory duct and an aedeagus containing an internal sac equipped with sclerotic scales. Based on their morphology, we draw conclusions about their functions. After spermatogenesis within the follicle, the spermatozoa become released from the sperm cysts...
2017: PloS One
https://www.readbyqxmd.com/read/28603536/molecular-transducers-from-roots-are-triggered-in-arabidopsis-leaves-by-root-knot-nematodes-for-successful-feeding-site-formation-a-conserved-post-embryogenic-de-novo-organogenesis-program
#17
Rocío Olmo, Javier Cabrera, Miguel A Moreno-Risueno, Hidehiro Fukaki, Carmen Fenoll, Carolina Escobar
Root-knot nematodes (RKNs; Meloidogyne spp.) induce feeding cells (giant cells; GCs) inside a pseudo-organ (gall) from still unknown root cells. Understanding GCs ontogeny is essential to the basic knowledge of RKN-plant interaction and to discover novel and effective control strategies. Hence, we report for the first time in a model plant, Arabidopsis, molecular, and cellular features concerning ectopic de novo organogenesis of RKNs GCs in leaves. RKNs induce GCs in leaves with irregular shape, a reticulated cytosol, and fragmented vacuoles as GCs from roots...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28543189/rapid-radiations-of-both-kiwifruit-hybrid-lineages-and-their-parents-shed-light-on-a-two-layer-mode-of-species-diversification
#18
Yifei Liu, Dawei Li, Qiong Zhang, Chi Song, Caihong Zhong, Xudong Zhang, Ying Wang, Xiaohong Yao, Zupeng Wang, Shaohua Zeng, Ying Wang, Yangtao Guo, Shuaibin Wang, Xinwei Li, Li Li, Chunyan Liu, Honour C McCann, Weiming He, Yan Niu, Min Chen, Liuwen Du, Junjie Gong, Paul M Datson, Elena Hilario, Hongwen Huang
Reticulate speciation caused by interspecific hybridization is now recognized as an important mechanism in the creation of biological diversity. However, depicting the patterns of phylogenetic networks for lineages that have undergone interspecific gene flow is challenging. Here we sequenced 25 taxa representing natural diversity in the genus Actinidia with an average mapping depth of 26× on the reference genome to reconstruct their reticulate history. We found evidence, including significant gene tree discordance, cytonuclear conflicts, and changes in genome-wide heterozygosity across taxa, collectively supporting extensive reticulation in the genus...
May 25, 2017: New Phytologist
https://www.readbyqxmd.com/read/28474724/interaction-of-silver-nanoparticles-with-metallothionein-and-ceruloplasmin-impact-on-metal-substitution-by-ag-i-corona-formation-and-enzymatic-activity
#19
Wei Liu, Isabelle A M Worms, Nathalie Herlin-Boime, Delphine Truffier-Boutry, Isabelle Michaud-Soret, Elisabeth Mintz, Claude Vidaud, Françoise Rollin-Genetet
The release of Ag(i) from silver nanoparticles (AgNPs) unintentionally spread in the environment is suspected to impair some key biological functions. In comparison with AgNO3, in-depth investigations were carried out into the interactions between citrate-coated AgNPs (20 nm) and two metalloproteins, intracellular metallothionein 1 (MT1) and plasmatic ceruloplasmin (Cp), both involved in metal homeostasis. These were chosen for their physiological relevance and the diversity of their various native metals bound because of thiol groups and/or their structural differences...
May 18, 2017: Nanoscale
https://www.readbyqxmd.com/read/28438125/chlamydia-spp-development-is-differentially-altered-by-treatment-with-the-lpxc-inhibitor-lpc-011
#20
Erik D Cram, Daniel D Rockey, Brian P Dolan
BACKGROUND: Chlamydia species are obligate intracellular bacteria that infect a broad range of mammalian hosts. Members of related genera are pathogens of a variety of vertebrate and invertebrate species. Despite the diversity of Chlamydia, all species contain an outer membrane lipooligosaccharide (LOS) that is comprised of a genus-conserved, and genus-defining, trisaccharide 3-deoxy-D-manno-oct-2-ulosonic acid Kdo region. Recent studies with lipopolysaccharide inhibitors demonstrate that LOS is important for the C...
April 24, 2017: BMC Microbiology
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