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https://www.readbyqxmd.com/read/29458151/endoscopic-management-of-pancreatobiliary-neoplasms
#1
Andrew Y Wang, Patrick S Yachimski
Endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) are the mainstays of interventional endoscopic practice. EUS occupies a central role in the diagnosis of pancreatobiliary neoplasms and offers a platform for a wide range of direct tumor therapies. Initial steps have demonstrated the feasibility of such applications in animal models and pilot studies. Larger clinical trials and incorporation of EUS-based therapies into cooperative cancer studies might demonstrate an impact in the clinical prognosis of patients with pancreatic cancer...
February 16, 2018: Gastroenterology
https://www.readbyqxmd.com/read/29457050/pelvic-catastrophe-after-elastic-band-ligation-in-an-irradiated-rectum
#2
Inês Pita, Pedro Bastos, Mário Dinis-Ribeiro
Chronic radiation proctopathy is a frequent complication after both pelvic external radiation therapy and brachytherapy and most commonly presents as rectal bleeding. Deep rectal ulcers and fistulae are much rarer and more clinically challenging consequences. We present the case of a 72-year-old male with a history of prostate adenocarcinoma treated with brachytherapy, who was referred to our institution due to a deep painful rectal ulcer refractory to medical treatment. The ulcer presented shortly after a haemorrhoid elastic band ligation and progressed to rectourethral fistulisation despite both faecal and urinary diversion...
January 2018: GE Portuguese Journal of Gastroenterology
https://www.readbyqxmd.com/read/29455924/gec-estro-acrop-recommendations-in-skin-brachytherapy
#3
Jose L Guinot, Agata Rembielak, Jose Perez-Calatayud, Silvia Rodríguez-Villalba, Janusz Skowronek, Luca Tagliaferri, Benjamin Guix, Victor Gonzalez-Perez, Vincenzo Valentini, György Kovacs
PURPOSE: The aim of this publication is to compile available literature data and expert experience regarding skin brachytherapy (BT) in order to produce general recommendations on behalf of the GEC-ESTRO Group. METHODS: We have done an exhaustive review of published articles to look for general recommendations. RESULTS: Randomized controlled trials, systemic reviews and meta-analysis are lacking in literature and there is wide variety of prescription techniques successfully used across the radiotherapy centers...
February 15, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29452902/retina-dose-as-a-predictor-for-visual-acuity-loss-in-106-ru-eye-plaque-brachytherapy-of-uveal-melanomas
#4
Gerd Heilemann, Lukas Fetty, Matthias Blaickner, Nicole Nesvacil, Martin Zehetmayer, Dietmar Georg, Roman Dunavoelgyi
BACKGROUND AND PURPOSE: To evaluate the retina dose as a risk factor associated with loss of visual acuity (VA) in 106 Ru plaque brachytherapy. MATERIAL/METHODS: 45 patients receiving 106 Ru plaques brachytherapy (median follow-up 29.5 months) were included in this study. An in-house developed treatment planning system with Monte Carlo based dose calculation was used to perform treatment planning and dose calculation. Risk factors associated with loss of VA were evaluated using the Cox proportional hazards models, Kaplan-Meier estimates and Pearson correlation coefficients...
February 13, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29452837/dramatically-polarized-opinion-on-the-role-of-brachytherapy-boost-in-management-of-high-risk-prostate-cancer-a-survey-of-north-american-genitourinary-expert-radiation-oncologists
#5
Shearwood McClelland, Kiri A Sandler, Catherine Degnin, Yiyi Chen, Timur Mitin
INTRODUCTION: Three randomized clinical trials have established brachytherapy (BT) boost in combination with external beam radiation therapy (EBRT) and androgen deprivation therapy (ADT) as superior to definitive EBRT and ADT alone in terms of biochemical control (but not overall survival) at the expense of increased toxicity in men with high-risk (HR) prostate cancer (PCa). The current view regarding these 2 treatment algorithms among North American genitourinary (GU) experts is not known...
February 2, 2018: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/29444756/local-recurrence-on-pet-ct-with-11-c-choline-following-brachytherapy-for-prostate-cancer-tracer-uptake-pattern
#6
J R Garcia, P Bassa, M Soler, F J Alvarez Moro, T Blanch, E Riera
No abstract text is available yet for this article.
February 11, 2018: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/29443851/corr-insights%C3%A2-does-an-algorithmic-approach-to-using-brachytherapy-and-external-beam-radiation-result-in-good-function-local-control-rates-and-low-morbidity-in-patients-with-extremity-soft-tissue-sarcoma
#7
https://www.readbyqxmd.com/read/29443850/does-an-algorithmic-approach-to-using-brachytherapy-and-external-beam-radiation-result-in-good-function-local-control-rates-and-low-morbidity-in-patients-with-extremity-soft-tissue-sarcoma
#8
Jason Klein, Alex Ghasem, Samuel Huntley, Nathan Donaldson, Martin Keisch, Sheila Conway
BACKGROUND: High-dose-rate brachytherapy (HDR-BT) and external-beam radiation therapy (EBRT) are two modalities used in the treatment of soft tissue sarcoma. Previous work at our institution showed early complications and outcomes for patients treated with HDR-BT, EBRT, or a combination of both radiation therapy modalities. As the general indications for each of these approaches to radiation therapy differ, it is important to evaluate the use of each in an algorithmic way, reflecting how they are used in contemporary practice at sites that use these treatments...
March 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29441104/current-status-of-brachytherapy-in-cancer-treatment-short-overview
#9
REVIEW
Janusz Skowronek
Cancer incidence and mortality depend on a number of factors, including age, socio-economic status and geographical location, and its prevalence is growing around the world. Most of cancer treatments include external beam radiotherapy or brachytherapy. Brachytherapy, a type of radiotherapy with energy from radionuclides inserted directly into the tumor, is increasingly used in cancer treatment. For cervical and skin cancers, it has become a standard therapy for more than 100 years as well as an important part of the treatment guidelines for other malignancies, including head and neck, skin, breast, and prostate cancers...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441103/complete-response-in-a-patient-with-gynecological-hidradenocarcinoma-treated-with-exclusive-external-beam-radiotherapy-and-brachytherapy-a-case-report
#10
Flavio Giannelli, Ilaria Chiola, Liliana Belgioia, Stefania Garelli, Alice Pastorino, Michela Marcenaro, Serafina Mammoliti, Sergio Costantini, Nicolò Bizzarri, Valerio Vellone, Salvina Barra, Renzo Corvò
Hidradenocarcinoma (HC) is a very rare disease. This case report illustrates a successful treatment of a 60-year-old woman with vulvo-vaginal localization of hidradenocarcinoma treated with external beam radiotherapy delivered by helical tomotherapy with a simultaneous integrated boost (SIB), followed by brachytherapy. External beam radiotherapy dose prescription was 50.4 Gy in 28 fractions, five fractions per week to whole pelvis (planning target volume 1 - PTV1), 60.2 Gy in 28 fractions to SIB1 (fundus of uterus and right inguinal node), and 58...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441102/dosimetric-analysis-of-rib-interference-of-the-ctv-during-interstitial-brachytherapy-of-lung-tumors
#11
Bo Yang, Xiaoyang Sun, Haowen Pang, Xiangxiang Shi, Tao Tang, Guangpeng Zhang, Renjin Chen, Jing Zhang, Hong Wu, Sheng Lin, Qinglian Wen, Yunwei Han, Jingbo Wu
Purpose: In interstitial brachytherapy for lung tumors, the placement and alignment of the source needles are influenced by the ribs, which can affect the dose distribution. This study evaluated the change in dose to the target by comparing the dose between the actual interstitial brachytherapy plan (AIBP, what is deliverable due to anatomic constraints), and the virtual interstitial brachytherapy plan (VIBP, pretreatment-modified dose distribution). Material and methods: AIBPs and VIBPs were designed for 20 lung tumors...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441101/high-dose-rate-brachytherapy-in-the-treatment-of-skin-kaposi-sarcoma
#12
María Ángeles González Ruiz, Juan Quirós Rivero, Julia Luisa Muñoz García, Joaquín José Cabrera Rodríguez, Yesika Ríos Kavadoy, María Francisca Ropero Carmona, Almudena Corbacho Campos, Fernando García Urra, María Cristina Cruz Muñoz, Amanda Ruiz Herrero, Pedro Almendral Manzano
Purpose: The aim of the study is to review our experience in treatment of Kaposi sarcoma (KS) lesions with high-dose-rate (HDR) brachytherapy. Material and methods: We present five new KS lesions (three patients) that were treated in our hospital from May 2016 to February 2017 with HDR brachytherapy using Valencia applicators. The treatment was delivered in 5 Gy fractions over five sessions, on alternate days. Total dose of 25 Gy (EQD2 31.25 Gy) was delivered. All patients were male, Caucasian, without a history of HIV, organ transplantation, or current immunosuppressive therapy...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441100/dose-volume-analysis-of-target-volume-and-critical-structures-in-computed-tomography-image-based-multicatheter-high-dose-rate-interstitial-brachytherapy-for-head-and-neck-cancer
#13
Hironori Akiyama, Tibor Major, Csaba Polgár, Zoltán Takácsi-Nagy
Purpose: To evaluate dose-volume relationships of target volume and critical structures in computed tomography (CT) image-based brachytherapy for head and neck cancer. Material and methods: Thirty-seven patients with mobile tongue, floor of mouth, and base of tongue cancer treated with brachytherapy (post-operative alone and as a boost after external beam radiotherapy [EBRT], or definitive alone or as a boost after EBRT) were selected. Treatment plans were made using post-implant CT images...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441099/ruthenium-brachytherapy-for-uveal-melanoma-single-institution-experience
#14
Iwona Rospond-Kubiak, Marta Wróblewska-Zierhoffer, Hanna Twardosz-Pawlik, Jarosław Kocięcki
Purpose: The aim of this study was to report on results of uveal melanoma treatment with ruthenium-106 ( 106 Ru) brachytherapy with long-term follow-up, in terms of local tumor control, eye retention rate, radiation retinopathy, and patients' survival. Material and methods: Medical records of patients treated with ruthenium plaque due to uveal melanoma at the Department of Ophthalmology, Poznan University of Medical Sciences, Poland, between 1994 and 2014 were retrospectively reviewed...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441098/nomogram-for-predicting-radiation-maculopathy-in-patients-treated-with-ruthenium-106-plaque-brachytherapy-for-uveal-melanoma
#15
Luca Tagliaferri, Monica Maria Pagliara, Carlotta Masciocchi, Andrea Scupola, Luigi Azario, Gabriela Grimaldi, Rosa Autorino, Maria Antonietta Gambacorta, Antonio Laricchiuta, Luca Boldrini, Vincenzo Valentini, Maria Antonietta Blasi
Purpose: To develop a predictive model and nomogram for maculopathy occurrence at 3 years after 106 Ru/ 106 Rh plaque brachytherapy in uveal melanoma. Material and methods: Clinical records of patients affected by choroidal melanoma and treated with 106 Ru/ 106 Rh plaque from December 2006 to December 2014 were retrospectively reviewed. Inclusion criteria were: dome-shaped melanoma, distance to the fovea > 1.5 mm, tumor thickness > 2 mm, and follow-up > 4 months...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441097/the-feasibility-of-using-ultrasound-during-follow-up-for-superficial-non-melanoma-skin-cancers-after-electronic-brachytherapy
#16
Uma Goyal, Justin Suszko, Baldassarre Stea
Purpose: Non-melanoma skin cancers (NMSCs) can be treated with a number of modalities including surgery, topical chemotherapy, or radiotherapy. Amongst the radiotherapeutic options, electronic brachytherapy (eBT) is an appealing treatment as it is usually given in a few fractions, it leads to good outcomes, and is increasingly being used. However, currently no follow-up imaging is routinely used or recommended to evaluate treatment response of NMSC. We aimed to use ultrasound (US) in follow-up after eBT for superficial NMSC to assess its feasibility in detecting possible tumor response...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441095/off-line-magnetic-resonance-imaging-navigation-of-cervix-cancer-brachytherapy-in-patients-with-risk-factors-for-uterine-perforation
#17
Noora Mohammed Al-Hammadi, Suparna Halsnad Chandramouli, Rabih Hammoud, Primoz Petric
Purpose: There are no reports on pre-insertion identification of cervix cancer patients at risk for uterine perforation during brachytherapy (BT). Our aim was to assess the incidence of risk factors in our patient cohort, and assess feasibility of a novel technique of magnetic resonance imaging (MRI)-guided navigation for applicator insertion (NAI) in high-risk cases. Material and methods: All patients with locally advanced cervical cancer, treated with image guided adaptive BT at our department between October 2013 and June 2017 were considered for analysis...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441094/artificial-neural-network-based-gynaecological-image-guided-adaptive-brachytherapy-treatment-planning-correction-of-intra-fractional-organs-at-risk-dose-variation
#18
Ramin Jaberi, Zahra Siavashpour, Mahmoud Reza Aghamiri, Christian Kirisits, Reza Ghaderi
Purpose: Intra-fractional organs at risk (OARs) deformations can lead to dose variation during image-guided adaptive brachytherapy (IGABT). The aim of this study was to modify the final accepted brachytherapy treatment plan to dosimetrically compensate for these intra-fractional organs-applicators position variations and, at the same time, fulfilling the dosimetric criteria. Material and methods: Thirty patients with locally advanced cervical cancer, after external beam radiotherapy (EBRT) of 45-50 Gy over five to six weeks with concomitant weekly chemotherapy, and qualified for intracavitary high-dose-rate (HDR) brachytherapy with tandem-ovoid applicators were selected for this study...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29441093/correlations-of-post-implant-regional-dosimetric-parameters-at-24-hours-and-one-month-with-clinical-results-of-low-dose-rate-brachytherapy-for-localized-prostate-cancer
#19
Eiichiro Okazaki, Katsuyuki Kuratsukuri, Kentaro Ishii, Tomoaki Tanaka, Ryo Ogino, Tomohiro Nishikawa, Hideyuki Morimoto, Masako Hosono, Yukio Miki
Purpose: To evaluate the correlations of post-implant regional dosimetrics at 24 hours (24 h) and 1 month after implant procedures, with clinical outcomes of low-dose-rate (LDR) brachytherapy for localized prostate cancer. Material and methods: Between January 2008 and December 2014, 130 consecutive patients treated for localized prostate cancer, receiving definitive iodine-125 ( 125 I) brachytherapy treatment were retrospectively analyzed. All patients underwent post-implant CT imaging for dosimetric analysis at 24 h and 1 month after implantation procedure...
December 2017: Journal of Contemporary Brachytherapy
https://www.readbyqxmd.com/read/29435083/evaluation-of-therapeutic-effects-of-125-i-particles-brachytherapy-for-recurrent-bladder-cancer
#20
Yu-Ming Zhou, Xiao Feng, Bing-Cheng Zhou, Yue-Feng Fan, Yuan-Liang Huang
The aim of the present study was to evaluate the clinical value of 125 I particles implantation in the treatment of recurrent bladder cancer. The study is a retrospective analysis of 32 patients with recurrent bladder cancer treated between May 2010 and January 2010. Of these, 16 cases (chemotherapy group) received conventional chemotherapy. A total of 16 patients ( 125 I group) received radiotherapy with 125 I particles, followed by conventional chemotherapy. By guidance of B ultrasound, 125 I radioactive particles were implanted...
March 2018: Oncology Letters
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