keyword
https://read.qxmd.com/read/38493444/integrative-regulation-of-hlmr1-by-dietary-and-genetic-factors-in-nonalcoholic-fatty-liver-disease-and-hyperlipidemia
#1
JOURNAL ARTICLE
Marcos E Jaso-Vera, Shohei Takaoka, Ishika Patel, Xiangbo Ruan
Long non-coding RNA (lncRNA) genes represent a large class of transcripts that are widely expressed across species. As most human lncRNAs are non-conserved, we recently employed a unique humanized liver mouse model to study lncRNAs expressed in human livers. We identified a human hepatocyte-specific lncRNA, hLMR1 (human lncRNA metabolic regulator 1), which is induced by feeding and promotes hepatic cholesterol synthesis. Recent genome-wide association studies (GWAS) found that several single-nucleotide polymorphisms (SNPs) from the hLMR1 gene locus are associated with blood lipids and markers of liver damage...
March 17, 2024: Human Genetics
https://read.qxmd.com/read/38492895/olfactory-ensheathing-cells-as-candidate-cells-for-chronic-pain-treatment
#2
REVIEW
Mei-Chen Liu, Qing-Fa Guo, Wei-Wei Zhang, Hong-Liang Luo, Wen-Jun Zhang, Hai-Jun Hu
Chronic pain is often accompanied by tissue damage and pain hypersensitivity. It easily relapses and is challenging to cure, which seriously affects the patients' quality of life and is an urgent problem to be solved. Current treatment methods primarily rely on morphine drugs, which do not address the underlying nerve injury and may cause adverse reactions. Therefore, in recent years, scientists have shifted their focus from chronic pain treatment to cell transplantation. This review describes the classification and mechanism of chronic pain through the introduction of the characteristics of olfactory ensheathing cells (OECs), an in-depth discussion of special glial cells through the phagocytosis of nerve debris, receptor-ligand interactions, providing nutrition, and other inhibition of neuroinflammation, and ultimately supporting axon regeneration and mitigation of chronic pain...
March 14, 2024: Journal of Chemical Neuroanatomy
https://read.qxmd.com/read/38492553/guidelines-to-restrict-consumption-of-red-meat-to-under-350-g-wk-based-on-colorectal-cancer-risk-are-not-consistent-with-health-evidence
#3
JOURNAL ARTICLE
Jane G Pouzou, Francisco J Zagmutt
BACKGROUND: The Nordic Nutrition Recommendations of 2023 (NNR2023) incorporate sustainability, health, and nutrition in their food-based dietary guidelines (FBDGs). NNR2023 recommends a consumption of ≤350 g/wk of unprocessed red meat (RM) based on association with colorectal cancer (CRC). This recommendation is lower than other FBDGs such as the World Cancer Research Fund (WCRF) recommendation it is based on (350-500 g/wk). OBJECTIVE: To evaluate the empirical evidence and models cited by the NNR2023 to support the RM guidance...
February 15, 2024: Nutrition
https://read.qxmd.com/read/38491970/assessment-of-the-risk-of-contamination-of-enteral-nutrition-bottles-based-on-the-simulation-of-home-use-conditions-and-hygiene-procedures
#4
JOURNAL ARTICLE
Isabela T F da Silva, Caroline O Medeiros, Jaqueline Leobet, Márcia R Beux, Estela I Rabito, Schaina A P Etgeton, Lize S Fiori
BACKGROUND: Home-prepared enteral formulations are supplied to patients through enteral nutrition bottles, via a gravity bag or other container, which may be inadequately sanitized and reused more times than recommended by the manufacturer. Such procedures increase the risk of contamination and can compromise the patient's clinical outcome. In light of this, the present study aimed to assess the risk of contamination of enteral nutrition bottles by simulating home use conditions and hygiene procedures...
March 16, 2024: Nutrition in Clinical Practice
https://read.qxmd.com/read/38491440/power-imbalances-and-equity-in-the-day-to-day-functioning-of-a-north-plus-multi-south-higher-education-institutions-partnership-a-case-study
#5
JOURNAL ARTICLE
Silondile Luthuli, Marguerite Daniel, J Hope Corbin
BACKGROUND: Partnerships between Higher Education Institutions (HEIs) in the global north and south have commonly been used as a vehicle to drive global health research and initiatives. Among these initiatives, include health system strengthening, research capacity building, and human resource training in developing countries. However, the partnership functioning of many global north-south partnerships still carry legacies of colonialism through unrecognized behavior patterns, attitudes, and belief systems in how they function...
March 15, 2024: International Journal for Equity in Health
https://read.qxmd.com/read/38490662/exploration-of-latina-hispanic-women-s-experiences-living-with-non-alcoholic-fatty-liver-disease-a-qualitative-study-with-patients-in-houston
#6
JOURNAL ARTICLE
Natalia I Heredia, Erika Mendoza Duque, Sylvia Ayieko, Amelia Averyt, Lorna H McNeill, Jessica P Hwang, Maria E Fernandez
OBJECTIVES: A deeper understanding of the lived experiences of Hispanic patients with non-alcoholic fatty liver disease (NAFLD) can help guide the development of behavioural programmes that facilitate NAFLD management. This paper explores Hispanic women's experiences living with NAFLD. DESIGN, SETTING, PARTICIPANTS: We collected brief sociodemographic questionnaires and conducted in-depth interviews with 12 low-income (all had household income ≤USD$55 000 per year) Hispanic women with NAFLD from the Houston area...
March 15, 2024: BMJ Open
https://read.qxmd.com/read/38490629/vegetable-and-fruit-wastes-valuable-source-for-organic-fertilizer-for-effective-growth-of-short-term-crops-solanum-lycopersicum-and-capsicum-annum
#7
JOURNAL ARTICLE
R Kavitha, Rajesh Dhanraj, Vijayakumar Natesan, Ying Ma, Sami Al Obaid, Mathiyazhagan Narayanan
Agriculture plays a vital role in the food security and economies of Asian countries. Annually, numerous metric tons of vegetable and fruit wastes are disposed of. This research aimed to convert the food wastes encompassing the vegetable and fruit wastes into solid and liquid organic fertilizer and to evaluate their influence on the growth (germination, phytochemicals, and biomolecules) of Solanum lycopersicum and Capsicum annum. Solanum lycopersicum, known as tomato, and Capsicum annum, known as bell pepper or chili pepper, are globally significant crops valued for their medicinal properties and economic importance...
March 13, 2024: Environmental Research
https://read.qxmd.com/read/38490385/stabilizing-effect-of-silver-carp-myofibrillar-protein-modified-by-high-intensity-ultrasound-on-high-internal-phase-emulsions-protein-denaturation-interfacial-adsorption-and-reconfiguration
#8
JOURNAL ARTICLE
Zehan Hong, Yaqiu Kong, Ruotong Guo, Qilin Huang
This study evaluated the impact of high intensity ultrasound (HIU) on myofibrillar proteins (MP) from silver carp, and investigated the stabilizing effect of HIU-treated MP (UMP) on high internal phase emulsions (HIPEs). Ultrasonic cavitation induced protein denaturation by decreasing size and unfolding conformation, to expose more hydrophobic groups, particularly UMP at 390 W, showing the smallest particle size (181.71 nm) and most uniform distribution. These structural changes caused that UMP under 390 W exhibited the highest surface hydrophobicity, solubility (92...
March 13, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38489991/longitudinal-change-of-intrinsic-capacity-and-associated-factors-in-older-chinese-adults-china-health-and-retirement-longitudinal-study
#9
JOURNAL ARTICLE
Fang Yang, Qin Su, Qin Ran, Yaoyue Hu
BACKGROUND: Although intrinsic capacity (IC) has been constructed in older populations, whether IC retains the same structure over time has not been formally examined, nor have the factors associated with the changes in IC over time been thoroughly investigated. This study aimed to establish that the structure of IC remains unchanged over time by testing its longitudinal measurement invariance and to investigate factors that influence the longitudinal change of IC over time. METHODS: Data came from 7,271 participants aged 60 and older from the China Health and Retirement Longitudinal Study in 2011 (Wave 1) and 2015 (Wave 3)...
March 14, 2024: Journal of Nutrition, Health & Aging
https://read.qxmd.com/read/38489716/prognostic-factors-for-surgical-site-infection-in-patients-with-spinal-metastases-and-following-surgical-treatment
#10
JOURNAL ARTICLE
Chen Song, Wanxi Zhang, Cheng Luo, Xiaoyong Zhao
There were few articles reviewed prognostic factors of surgical site infection (SSI) in patients with spinal metastases following surgery. The purpose of the present study was to systematically: (1) investigate the incidence rates of SSI following spinal metastases surgery; (2) identify the factors which were independently associated with postoperative wound infection. One hundred sixty-seven consecutive adult patients with spinal metastases and underwent surgical treatment were retrospectively enrolled from January 2011 to February 2022...
March 15, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38489525/facilitators-and-barriers-of-wet-nursing-from-antiquity-to-the-present-a-narrative-review-with-implications-for-emergencies
#11
REVIEW
Khadija Abdelrahmman, Bindi Borg, Seema Mihrshahi, Karleen Gribble
Background: If maternal breastfeeding is not possible, wet nursing allows infants to receive the nutrition and protection against disease that breastfeeding provides. Such protection may be particularly valuable in emergencies. However, while wet nursing is recommended in the Operational Guidance on Infant and Young Child Feeding in Emergencies it is underutilized. This narrative review aimed to develop an understanding of wet nursing practice across time and location, and why wet nursing is currently so little supported to inform interventions to support wet nursing in emergencies...
March 2024: Breastfeeding Medicine
https://read.qxmd.com/read/38489346/care-groups-in-an-integrated-nutrition-education-intervention-improved-infant-growth-among-south-sudanese-refugees-in-uganda-s-west-nile-post-emergency-settlements-a-cluster-randomized-trial
#12
JOURNAL ARTICLE
Joel J Komakech, Sam R Emerson, Ki L Cole, Christine N Walters, Hasina Rakotomanana, Margaret K Kabahenda, Deana A Hildebrand, Barbara J Stoecker
OBJECTIVE: This study examined the effects of a peer-led integrated nutrition education intervention with maternal social support using Care Groups on infant growth among South Sudanese refugees in Uganda. METHODS: A community-based cluster-randomized trial (RCT) was conducted among 390 pregnant women (third trimester). Two intervention study arms were Mothers-only(n = 131) and Parents-combined (n = 142) with a Control (n = 117). WHO infant growth standards defined length-for-age z-scores (LAZ) for stunting, weight-for-age z-scores (WAZ) for underweight and weight-for-length z-scores (WLZ) for wasting...
2024: PloS One
https://read.qxmd.com/read/38489293/multidimensional-evaluation-of-the-early-emergence-of-executive-function-and-development-in-bangladeshi-children-using-nutritional-and-psychosocial-intervention-a-randomized-controlled-trial-protocol
#13
JOURNAL ARTICLE
Talat Shama, Justin M O'Sullivan, Navin Rahman, Shahria H Kakon, Fahmida Tofail, Md Iqbal Hossain, Mamane Zeilani, Rashidul Haque, Peter Gluckman, Terrence Forrester, Charles A Nelson
INTRODUCTION: Reversing malnutrition-induced impairment of cognition and emotional regulation is a critical global gap. We hypothesize that brain-targeted micronutrient supplemented nutritional rehabilitation in children with moderate acute malnutrition, followed by 2 years micronutrient supplementation will impact on the cognition and emotion regulation of these children. METHODS: The primary outcome of this prospective, randomized controlled trial is to study the development of executive functions (EFs) and emotion regulation (ER) in this cohort...
2024: PloS One
https://read.qxmd.com/read/38488556/unraveling-the-gut-brain-axis-the-impact-of-steroid-hormones-and-nutrition-on-parkinson-s-disease
#14
JOURNAL ARTICLE
Paula Maria Neufeld, Ralf A Nettersheim, Veronika Matschke, Matthias Vorgerd, Sarah Stahlke, Carsten Theiss
This comprehensive review explores the intricate relationship between nutrition, the gut microbiome, steroid hormones, and Parkinson's disease within the context of the gut-brain axis. The gut-brain axis plays a pivotal role in neurodegenerative diseases like Parkinson's disease, encompassing diverse components such as the gut microbiota, immune system, metabolism, and neural pathways. The gut microbiome, profoundly influenced by dietary factors, emerges as a key player. Nutrition during the first 1000 days of life shapes the gut microbiota composition, influencing immune responses and impacting both child development and adult health...
October 1, 2024: Neural Regeneration Research
https://read.qxmd.com/read/38488242/age-related-and-cancer-related-sarcopenia-is-there-a-difference
#15
JOURNAL ARTICLE
Federico Bozzetti
PURPOSE: The aim of this review is the attempt to differentiating the pathophysiologic and clinical features of the aging-related sarcopenia from cancer-related sarcopenia. In fact, there is some controversy among the experts mainly regarding two points: is always sarcopenia, even that aging-related one, the expression of a generalized disease or may exist independently and without major alteration of the muscle function? Are always aging-related and cancer-related sarcopenia completely separated entities? RECENT FINDINGS: Literature shows that sarcopenia, defined as simple skeletal muscle mass loss, may range from a mainly focal problem which is common in many healthy elderly people, to a component of a complex multiorgan syndrome as cancer cachexia...
March 14, 2024: Current Opinion in Clinical Nutrition and Metabolic Care
https://read.qxmd.com/read/38488112/microbiome-and-its-impact-on-fetal-and-neonatal-brain-development-current-opinion-in-pediatrics
#16
JOURNAL ARTICLE
Nina M Frerichs, Tim G J de Meij, Hendrik J Niemarkt
PURPOSE OF REVIEW: Emerging evidence suggests that the gut microbiota and its metabolites regulate neurodevelopment and cognitive functioning via a bi-directional communication system known as the microbiota-gut-brain axis (MGBA). RECENT FINDINGS: The MGBA influences brain development and function via the hypothalamic-pituitary axis, the vagal nerve, immune signaling, bacterial production of neurotransmitters, and microbial metabolites like short-chain fatty acids, tryptophan derivatives, and bile acids...
March 11, 2024: Current Opinion in Clinical Nutrition and Metabolic Care
https://read.qxmd.com/read/38487898/breastfeeding-moderates-the-association-of-maternal-pre-pregnancy-nutritional-status-with-offspring-body-composition-at-30-years
#17
JOURNAL ARTICLE
Bernardo L Horta, Kelly P Coca, Mina Desai, Mariane S Dias, Manoella B Jaccottet, Michael G Ross
Maternal pre-pregnancy body mass index is positively associated with offspring obesity, even at adulthood, whereas breastfeeding decreases the risk of obesity. The present study was aimed at assessing whether breastfeeding moderates the association of maternal pre-pregnancy body mass index with offspring body composition at adulthood, using data from 3439 subjects enrolled in a southern Brazilian birth cohort. At 30 years of age, maternal pre-pregnancy body mass index was positively associated with offspring prevalence of obesity, abdominal obesity, as well as body mass index and fat and lean mass index...
March 15, 2024: Journal of Developmental Origins of Health and Disease
https://read.qxmd.com/read/38487629/expert-consensus-on-nutrition-and-lower-carbohydrate-diets-an-evidence-and-equity-based-approach-to-dietary-guidance
#18
REVIEW
Jeff S Volek, William S Yancy, Barbara A Gower, Stephen D Phinney, Joanne Slavin, Andrew P Koutnik, Michelle Hurn, Jovonni Spinner, Mark Cucuzzella, Frederick M Hecht
There is a substantial body of clinical evidence supporting the beneficial effects of lower-carbohydrate dietary patterns on multiple established risk factors associated with insulin resistance and cardiovascular diseases in adult populations. Nutrition and health researchers, clinical practitioners, and stakeholders gathered for, "The Scientific Forum on Nutrition, Wellness, and Lower-Carbohydrate Diets: An Evidence- and Equity-Based Approach to Dietary Guidance" to discuss the evidence base around lower-carbohydrate diets, health outcomes, and dietary guidance...
2024: Frontiers in Nutrition
https://read.qxmd.com/read/38487626/caregiver-self-efficacy-providing-nutritional-support-for-pediatric-patients-undergoing-hematopoietic-stem-cell-transplant-is-associated-with-psychosocial-factors
#19
JOURNAL ARTICLE
Leah LaLonde, Alexandra Neenan, Michelle Byrd, Flora Hoodin, Sandra Bouma, Sung Won Choi
INTRODUCTION: Caregiver self-efficacy in providing nutritional support to pediatric hematopoietic stem cell transplantation (HSCT) patients has been little studied despite the increased risk of these children potentially being over- or under-nourished after HSCT, and nutritional status could possibly affect treatment outcomes. The current study aimed to describe caregiver dietary self-efficacy and its associated psychosocial factors and barriers to following dietary recommendations. METHODS: Caregivers completed questionnaires pre-HSCT and 30 days, 100 days, and one year post-HSCT...
2024: Frontiers in Nutrition
https://read.qxmd.com/read/38487150/bolus-versus-continuous-enteral-feeding-for-critically-ill-patients-a-systematic-review-and-meta-analysis
#20
REVIEW
Ahmed M Abdelbaky, Wael G Elmasry, Ahmed H Awad
Enteral feeding is a crucial aspect of nutritional support for critically ill patients. However, the optimal feeding approach, whether bolus or continuous, remains a subject of debate. This systematic review and meta-analysis aimed to compare the outcomes of bolus feeding and continuous enteral feeding in critically ill patients. A systemic search was carried out in PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL) Ultimate, Web of Science, Scopus, and Google Scholar to identify relevant studies...
February 2024: Curēus
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