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Pelvic chronic pain

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https://www.readbyqxmd.com/read/29218704/sacral-neuromodulation-for-pelvic-pain-and-pelvic-organ-dysfunction-a-case-series
#1
Thierry Vancaillie, Lauren Kite, Elizabeth Howard, Jason Chow
BACKGROUND: The use of neuromodulation is growing and it is an established therapy for conditions such as bladder dysfunction. It is an increasingly used therapy for the management of chronic perineal pain but little research is currently available looking at its efficacy. AIM: We present a series of 52 patients who underwent placement of a neuromodulator, the majority of whom suffered from perineal pain, with most placements via the sacral hiatus. METHOD: Patients were asked to complete a survey recalling their symptoms prior to implantation and describing their symptoms and experience after...
December 8, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29218074/autophagy-in-endometriosis
#2
REVIEW
Hui-Li Yang, Jie Mei, Kai-Kai Chang, Wen-Jie Zhou, Li-Qing Huang, Ming-Qing Li
Endometriosis (EMS) is a common gynecologic disease that causes chronic pelvic pain, dysmenorrhea, and infertility in women. The doctrine of menstruation back flow planting and defects in the immune system are well known and widely accepted. In recent years, increasing studies have been focused on the role of autophagy in EMS, and have shown that autophagy plays a vital role in EMS. Autophagy, which is known as the non-apoptotic form of programmed cell death induced by a large number of intracellular/extracellular stimuli, is the major cellular pathway for the degradation of long-lived proteins and cytoplasmic organelles in eukaryotic cells...
2017: American Journal of Translational Research
https://www.readbyqxmd.com/read/29215841/-histamine-metabolism-disorder-in-pathogenesis-of-chronic-pelvic-pain-in-patients-with-external-genital-endometriosis
#3
M R Orazov, V Y Radzinskiy, M B Khamoshina, E N Nosenko, E S Tokaeva, L K Barsegyan, Y R Zakirova
Objective. To study features of histamine metabolism in patients with chronic pelvic pain associated with external genital endometriosis. Methods. For quantitative assessment of histamine level in peripheral blood was taken from 100 patients which than was centrifuged. In blood serum histamine concentration was determined by enzyme-linked immunosorbent assay method with reagents «Histamine ЕLISA» on the machine BAE-1000 Histamine (Labor Diagnostika Nord - LDN, Hermany). A pain syndrome was assessed by Visual Analog Scale (VAS), quality of life assessment - by Endometriosis Health Profile Questionnaire (EHR-30), level of anxiety was determined by Spielberger-Khanin questionnaire...
April 2017: Patologicheskaia Fiziologiia i èksperimental'naia Terapiia
https://www.readbyqxmd.com/read/29215508/opioid-knowledge-and-prescribing-practices-among-obstetrician-gynecologists
#4
Annetta M Madsen, Lauren M Stark, Phinnara Has, Jenna B Emerson, Jay Schulkin, Kristen A Matteson
OBJECTIVE: To describe obstetrician-gynecologists' (ob-gyns) knowledge and prescribing practices regarding opioid analgesics. METHODS: We conducted a cross-sectional survey of a national sample of American College of Obstetricians and Gynecologists Fellows and Junior Fellows who are part of the Collaborative Ambulatory Research Network. We used a sequential mixed-method approach. We collected data on opioid knowledge and typical prescribing practices, including number, type, and indication for prescriptions...
December 4, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29213359/influence-of-radiation-treatment-technique-on-outcome-and-toxicity-in-anal-cancer
#5
Elisha T Fredman, May Abdel-Wahab, Aryavarta M S Kumar
Objective: Intensity-modulated radiation therapy (IMRT) has largely supplanted three-dimensional conformal radiation (3D-CRT) for definitive anal cancer treatment due to decreased toxicity and potentially improved outcomes. Convincing data demonstrating its advantages, however, remain limited. We compared outcomes and toxicity with concurrent chemotherapy and IMRT vs 3D-CRT for anal cancer. Methods: We performed a single-institution retrospective review of patients treated with IMRT or 3D-CRT as part of definitive mitomycin-C/5-fluorouricil-based chemoradiation for anal cancer from January 2003 to December 2012...
2017: Journal of Radiation Oncology
https://www.readbyqxmd.com/read/29205996/current-management-of-ovarian-endometriomas
#6
Ludovico Muzii, Chiara DI Tucci, Daniele DI Mascio, Mara DI Feliciantonio, Oriana Capri, Daniela Pietrangeli, Francesco Rech, Pierluigi Benedetti Panici
The choice of treatment in case of ovarian endometriomas is one of the most discussed topics in Reproductive Medicine. Management options include expectancy, medical treatment, surgery, in-vitro fertilization (IVF), or a combination of the above. The main presenting symptom, i.e. pain or infertility, usually guide the choice of treatment. Medical treatment is usually preferred as the first line option when pain is the associated symptom, whereas surgery or IVF are preferred in case of associated infertility...
December 4, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/29205874/establishment-of-experimental-autoimmune-prostatitis-model-by-t2-peptide-in-aluminium-hydroxide-adjuvant
#7
L Zhang, A U Ihsan, Y Cao, Y Cheng, X Zhou
A mouse model was developed to simulate the clinical features of chronic prostatitis/chronic pelvic pain syndrome using peptide (T2 ). Forty C57BL/6 mice were divided into four groups of 10 mice each, averagely and randomly. T2 plus aluminium hydroxide adjuvant group was given subcutaneous injection with the emulsion mixture of T2 and aluminium hydroxide adjuvant, the T2 group with T2 , the aluminium hydroxide adjuvant group with aluminium hydroxide adjuvant and the normal control group with 0.9/% NaCl solution...
December 4, 2017: Andrologia
https://www.readbyqxmd.com/read/29201643/relationships-between-brain-metabolite-levels-functional-connectivity-and-negative-mood-in-urologic-chronic-pelvic-pain-syndrome-patients-compared-to-controls-a-mapp-research-network-study
#8
Daniel E Harper, Eric Ichesco, Andrew Schrepf, Megan Halvorson, Tudor Puiu, Daniel J Clauw, Richard E Harris, Steven E Harte
Until recently, the predominant pathology of chronic pelvic pain conditions was thought to reside in the peripheral tissues. However, mounting evidence from neuroimaging studies suggests an important role of the central nervous system in the pathogenesis of these conditions. In the present cross-sectional study, proton magnetic resonance spectroscopy (1H-MRS) of the brain was conducted in female patients with urologic chronic pelvic pain syndrome (UCPPS) to determine if they exhibit abnormal concentrations of brain metabolites (e...
2018: NeuroImage: Clinical
https://www.readbyqxmd.com/read/29197987/surgery-in-adenomyosis
#9
Marco Aurelio Pinho Oliveira, Claudio Peixoto Crispi, Leila Cristina Brollo, Claudio Peixoto Crispi, Rudy Leon De Wilde
INTRODUCTION: Adenomyosis is defined as the presence of endometrial glands and stroma within the myometrium. The true prevalence is unknown and has been reported to range from 1 to 70%. It has a significantly negative impact on women's quality of life, causing abnormal uterine bleeding, dysmenorrhea, and chronic pelvic pain. The definitive treatment for adenomyosis is hysterectomy, although it does not contemplate patients who wish to preserve their fertility. The aim of this paper is to discuss the latest evidence on the surgical techniques for the treatment of adenomyosis published in medical-scientific databases...
December 2, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29193813/a-case-report-of-brown-tumor-in-a-patient-with-chronic-renal-failure-and-renal-cell-carcinoma
#10
Yong-Jun Liu, Elizabeth E Frauenhoffer, Eric Walker, Nicole C Williams
We report a case of a 72 year old male with hyperparathyroidism secondary to end stage diabetic renal disease and coexisting bilateral chromophobe renal cell carcinomas. The patient presented with back and groin pain, right pelvic hemorrhage, and multiple lytic bone lesions concerning for metastatic renal cell carcinoma. Fine needle aspiration cytology demonstrated benign appearing osteoclasts and spindled cells. A concurrent core biopsy showed foci of spindled cell proliferation populated by osteoclast-like giant cells with stromal hemorrhage without evidence of metastatic carcinoma...
November 29, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29184791/comprehensive-pelvic-floor-physical-therapy-program-for-men-with-idiopathic-chronic-pelvic-pain-syndrome-a-prospective-study
#11
Thomas A Masterson, John M Masterson, Jessica Azzinaro, Lattoya Manderson, Sanjaya Swain, Ranjith Ramasamy
Background: Male chronic pelvic pain syndrome (CPPS) is a heterogeneous constellation of symptoms that causes significant impairment and is often challenging to treat. In this prospective study, we evaluated men with CPPS who underwent comprehensive pelvic floor physical therapy (PFPT) program. We used the previously validated Genitourinary Pain Index (GUPI) to measure outcomes. Methods: We included 14 men who underwent physical therapy for idiopathic CPPS from October 2015 to October 2016...
October 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29184711/adult-sacrococcygeal-teratoma-with-coccygectomy-a-case-report-with-a-review-of-the-literature
#12
Daniel Diaz-Aguilar, Sergei Terterov, Rudi Scharnweber, Catherine Merna, Stephanie Wang, Shayan Rahman
Background: Saccrococcygeal teratomas (SCT) are derived from embryonic germ cell layers. They frequently present at the base of the coccyx within the pelvis. While these tumors are common in children, they are exceedingly rare in adults. In adults, a majority of these tumors are intrapelvic and associated with a low risk of malignant transformation. Therefore, this contributes to a good prognosis following resection of mostly benign lesions. Case Description: An adult female with chronic pelvic pain presented with a sacral teratoma...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/29172883/prevalence-correlates-of-chronic-perinatal-pain-a-study-from-india
#13
Geetha Desai, G Sunil Kumar, L Manoj, G R Gokul, K V Beena, K Thennarasu, T S Jaisoorya
OBJECTIVES: To study the prevalence of chronic perinatal pain among mothers who had infants between the ages of 13-25 months in the State of Kerala, India and to report its correlates in the socio-demographic, obstetric and psychological domains. METHODS: A total of 9305 mothers selected by cluster random sampling were assessed cross-sectionally for chronic perinatal pain using a questionnaire by Junior Public Health Nurses (JPHNs). In addition, information regarding socio-demographic profile, obstetric history, infant details and perinatal depression were collected...
November 27, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29166313/the-perineal-turnover-perforator-flap-a-new-and-simple-technique-for-perineal-reconstruction-after-extralevator-abdominoperineal-excision
#14
Maria Chasapi, Mohamed Maher, Peter Mitchell, Milind Dalal
BACKGROUND: Extralevator abdominoperineal excision (ELAPE) is increasingly used to treat locally advanced low rectal cancer as it has been related to superior oncological outcomes than traditional abdominoperineal excision.However, ELAPE also has been associated with high perineal wound morbidity rates as it creates a larger perineal cavity than standard abdominoperineal excision. This greater defect, along with the effects of preoperative chemoradiation on wound healing, makes uneventful perineal reconstruction post-ELAPE a real challenge for the plastic surgeon...
November 21, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29157875/prostatic-calculi-do-they-matter
#15
REVIEW
Jun-Jie Cao, Wei Huang, Hong-Shen Wu, Min Cao, Yan Zhang, Xiao-Dong Jin
INTRODUCTION: Prostatic calculi (PC) are frequently detected at computed tomography or ultrasound in men attending the health center or the urology outpatient department. PC have attracted more attention from urologists, but the clinical significance of PC is unknown. AIM: To review the available literature on the effects of PC on prostatic diseases and sexual function in men. METHODS: Relevant clinical trials were identified by searching the PubMed, Embase, and Cochrane Library databases...
November 17, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29146678/cross-organ-sensitisation-between-the-colon-and-bladder-to-pee-or-not-to-pee
#16
Luke Grundy, Stuart M Brierley
Chronic abdominal and pelvic pain are common, debilitating clinical conditions experienced by millions of patients around the globe. The origin of such pain commonly arises from the intestine and bladder, which share common primary roles; the collection, storage and expulsion of waste. These visceral organs are located in close proximity to one another, and also share common innervation from spinal afferent pathways. Chronic abdominal pain, constipation or diarrhoea are primary symptoms for patients with Irritable Bowel Syndrome (IBS) or Inflammatory Bowel Disease (IBD)...
November 16, 2017: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/29144908/re-prevalence-of-sexual-dysfunction-in-men-with-chronic-prostatitis-chronic-pelvic-pain-syndrome-a-meta-analysis
#17
Edward M Schaeffer
No abstract text is available yet for this article.
December 2017: Journal of Urology
https://www.readbyqxmd.com/read/29138912/long-term-follow-up-after-non-operative-management-of-blunt-splenic-and-liver-injuries-a-questionnaire-based-survey
#18
Peter Moreno, Matthias Von Allmen, Tobias Haltmeier, Daniel Candinas, Beat Schnüriger
BACKGROUND: Non-operative management (NOM) of blunt splenic or liver injuries (solid organ injury, SOI) has become the standard of care in hemodynamically stable patients. However, the incidence of long-term symptoms in these patients is currently not known. The aim of this study was to assess long-term symptoms in patients undergoing successful NOM (sNOM) for SOI. METHODS: Long-term posttraumatic outcomes including chronic abdominal pain, irregular bowel movements, and recurrent infections were assessed using a specifically designed questionnaire and analyzed by univariable analysis...
November 14, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29132932/apoptotic-effect-as-biomarker-of-disease-severity-and-follow-up-in-interstitial-cystitis
#19
C Di Capua-Sacoto, A Sanchez-Llopis, J E Oconnor, A Martinez-Romero, J L Ruiz-Cerdá
OBJECTIVE: To determine whether the apoptotic effect test could serve as a biomarker of severity in bladder pain syndrome/interstitial cystitis. MATERIAL AND METHODS: A prospective study was conducted between January 2010 and January 2015, which included 57 patients diagnosed with interstitial cystitis and 49 diagnosed with chronic pelvic pain of gynaecological origin. The urine was exposed to cell cultures, and the urine's capacity for inducing apoptosis in the cultures was analysed...
November 10, 2017: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/29131768/from-inguinal-hernias-to-spermatic-cord-lipomas-pearls-pitfalls-and-mimics-of-abdominal-and-pelvic-hernias
#20
Miguel C Cabarrus, Benjamin M Yeh, Andrew S Phelps, Jao J Ou, Spencer C Behr
Abdominal and pelvic hernias may be indolent and detected incidentally, manifest acutely with pain and distress, or cause chronic discomfort. Physical examination findings are often ambiguous and insufficient for optimal triage. Therefore, accurate anatomic delineation and identification of complications are critical for effective treatment planning. Imaging, particularly computed tomography, provides a vital understanding of the hernia's location and size, involved viscera, and severity of associated complications...
November 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
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