keyword
MENU ▼
Read by QxMD icon Read
search

co-twin

keyword
https://www.readbyqxmd.com/read/27906038/craniopagus-parasiticus-a-parasitic-head-protruding-from-temporal-area-of-cranium-a-case-report
#1
Wassihun Nega, Meku Damte, Yonas Girma, Getachew Desta, Mengistu Hailemariam
BACKGROUND: Craniopagus parasiticus is rare with an incidence of approximately four to six cases in 10,000,000 births. In our case, the head of the parasitic twin protruded from the temporal area of the normal twin's cranium. The parasitic twin had two deformed lower limbs, of which one was rudimentary, and long bones of the bilateral lower limbs and some pelvic bone. Dissection of the mass of the parasitic twin's body revealed the intestine but no chest organs or abdominal organs. There was a rudimentary labium but no vaginal opening...
December 1, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27898952/frequency-of-leukochimerism-in-holstein-and-jersey-twinsets
#2
A S Young, B W Kirkpatrick
The current study was conducted to test breed difference in the frequency of leukochimerism. This study used leukochimerism as evidence of placental vascular anastomosis formation and compared its frequency in the Holstein and Jersey breeds. We test the null hypothesis that there is no difference in incidence of leukochimerism in the Holstein and Jersey breeds. Hair and blood samples were collected from 85 Jersey twinsets and 80 Holstein twinsets, ranging in age from 1 d to 8 yr. An additional 7 Holstein twinsets (6 complete and 1 partial where 1 twin died) were sampled originally 48 to 72 h after birth and resampled at 5 to 10 mo of age to provide an assessment of whether leukochimerism changed with age...
November 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27898055/increased-dna-methylation-variability-in-type-1-diabetes-across-three-immune-effector-cell-types
#3
Dirk S Paul, Andrew E Teschendorff, Mary A N Dang, Robert Lowe, Mohammed I Hawa, Simone Ecker, Huriya Beyan, Stephanie Cunningham, Alexandra R Fouts, Anita Ramelius, Frances Burden, Samantha Farrow, Sophia Rowlston, Karola Rehnstrom, Mattia Frontini, Kate Downes, Stephan Busche, Warren A Cheung, Bing Ge, Marie-Michelle Simon, David Bujold, Tony Kwan, Guillaume Bourque, Avik Datta, Ernesto Lowy, Laura Clarke, Paul Flicek, Emanuele Libertini, Simon Heath, Marta Gut, Ivo G Gut, Willem H Ouwehand, Tomi Pastinen, Nicole Soranzo, Sabine E Hofer, Beate Karges, Thomas Meissner, Bernhard O Boehm, Corrado Cilio, Helena Elding Larsson, Åke Lernmark, Andrea K Steck, Vardhman K Rakyan, Stephan Beck, R David Leslie
The incidence of type 1 diabetes (T1D) has substantially increased over the past decade, suggesting a role for non-genetic factors such as epigenetic mechanisms in disease development. Here we present an epigenome-wide association study across 406,365 CpGs in 52 monozygotic twin pairs discordant for T1D in three immune effector cell types. We observe a substantial enrichment of differentially variable CpG positions (DVPs) in T1D twins when compared with their healthy co-twins and when compared with healthy, unrelated individuals...
November 29, 2016: Nature Communications
https://www.readbyqxmd.com/read/27889677/blood-dna-methylation-age-is-not-associated-with-cognitive-functioning-in-middle-aged-monozygotic-twins
#4
A Starnawska, Q Tan, A Lenart, M McGue, O Mors, A D Børglum, K Christensen, M Nyegaard, L Christiansen
The epigenetic clock, also known as DNA methylation age (DNAmAge), represents age-related changes of DNA methylation at multiple sites of the genome and is suggested to be a biomarker for biological age. Elevated blood DNAmAge is associated with all-cause mortality, with the strongest effects reported in a recent intrapair twin study where epigenetically older twins had increased mortality risk in comparison to their co-twins. In the study presented here, we hypothesize that DNAmAge in blood is associated with cross-sectional and longitudinal cognitive abilities in middle-aged individuals...
November 4, 2016: Neurobiology of Aging
https://www.readbyqxmd.com/read/27886578/kynurenic-acid-and-psychotic-symptoms-and-personality-traits-in-twins-with-psychiatric-morbidity
#5
Magdalena E Kegel, Viktoria Johansson, Lennart Wetterberg, Maria Bhat, Lilly Schwieler, Tyrone D Cannon, Ina Schuppe-Koistinen, Göran Engberg, Mikael Landén, Christina M Hultman, Sophie Erhardt
Increased cytokines and kynurenic acid (KYNA) levels in cerebrospinal fluid (CSF) have been reported in patients with schizophrenia and bipolar disorder. The aim of the present study was to investigate cytokines and kynurenines in the CSF of twin pairs discordant for schizophrenia or bipolar disorder and to study these CSF markers in relation to psychotic symptoms and personality traits. CSF levels of tryptophan (TRP), KYNA, quinolinic acid (QUIN), interleukin (IL)-6, IL-8 and tumor necrosis factor-alpha (TNF-α) were analyzed in 23 twins with schizophrenia or bipolar disorder, and in their not affected co-twins...
November 16, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27872260/familial-aggregation-and-heritability-of-schizophrenia-and-co-aggregation-of-psychiatric-illnesses-in-affected-families
#6
I-Jun Chou, Chang-Fu Kuo, Yu-Shu Huang, Matthew J Grainge, Ana M Valdes, Lai-Chu See, Kuang-Hui Yu, Shue-Fen Luo, Lu-Shuang Huang, Wen-Yi Tseng, Weiya Zhang, Michael Doherty
Strong familial aggregation of schizophrenia has been reported but there is uncertainty concerning the degree of genetic contribution to the phenotypic variance of the disease. This study aimed to examine the familial aggregation and heritability of schizophrenia, and the relative risks (RRs) of other psychiatric diseases, in relatives of people with schizophrenia using the Taiwan National Health Insurance Database. The study population included individuals with affected first-degree or second-degree relatives identified from all beneficiaries (n = 23 422 955) registered in 2013...
November 21, 2016: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/27852351/remembering-irving-i-gottesman-twin-research-colleague-and-friend-extraordinaire-research-studies-face-lift-technique-comparison-in-identical-twins-raising-preterm-twins-fetal-behavior-in-dichorionic-twin-pregnancies-co-bedding-and-stress-reduction-in-twins
#7
Nancy L Segal
Dr Irving I. Gottesman, a colleague, friend, and long-time member of the International Society of Twin Studies passed away on June 29, 2016. His contributions to twin research and some personal reflections are presented to honor both the man and the memory. This tribute is followed by short reviews of twin research concerning differences between cosmetic surgical techniques, the rearing of preterm twins, behavioral observations of dichorionic fetal twins, and the outcomes of co-bedding twins with reference to stress reduction...
December 2016: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/27814340/childhood-bullying-victimization-and-overweight-in-young-adulthood-a-cohort-study
#8
Jessie R Baldwin, Louise Arseneault, Candice Odgers, Daniel W Belsky, Timothy Matthews, Antony Ambler, Avshalom Caspi, Terrie E Moffitt, Andrea Danese
OBJECTIVE: To test whether bullied children have an elevated risk of being overweight in young adulthood and whether this association is: (1) consistent with a dose-response relationship, namely, its strength increases with the chronicity of victimization; (2) consistent across different measures of overweight; (3) specific to bullying and not explained by co-occurring maltreatment; (4) independent of key potential confounders; and (5) consistent with the temporal sequence of bullying preceding overweight...
November 2016: Psychosomatic Medicine
https://www.readbyqxmd.com/read/27809652/liver-fat-and-insulin-sensitivity-define-metabolite-profiles-during-a-glucose-tolerance-test-in-young-adult-twins
#9
Joel T Rämö, Sanna M Kaye, Sakari Jukarainen, Leonie H Bogl, Antti Hakkarainen, Jesper Lundbom, Nina Lundbom, Aila Rissanen, Jaakko Kaprio, Niina Matikainen, Kirsi H Pietiläinen
CONTEXT: The associations of BMI and liver fat (LF) with circulating prandial metabolomic markers are incompletely understood. OBJECTIVE: To characterize circulating metabolite excursions during an oral glucose tolerance test (OGTT), and evaluate whether the metabolomic signatures of BMI-discordance co-associate with LF content. DESIGN, SETTING AND PARTICIPANTS: We measured 80 metabolite parameters by nuclear magnetic resonance, together with glucose and insulin, during a 2-hour OGTT in 64 monozygotic and 73 dizygotic twin pairs (aged 22...
November 3, 2016: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27794503/modifiable-risk-factors-for-chronic-back-pain-insights-using-the-co-twin-control-design
#10
Pradeep Suri, Edward J Boyko, Nicholas L Smith, Jeffrey G Jarvik, Frances M K Williams, Gail P Jarvik, Jack Goldberg
BACKGROUND: Inconsistent associations between modifiable risk factors and chronic back pain (CBP) may be due to the inability of traditional epidemiologic study designs to properly account for an array of potential genetic and environmental confounding factors. The co-twin control research design, comparing modifiable risk factors in twins discordant for CBP, offers a unique way to remove numerous confounding factors. PURPOSE: The study aimed to examine the association of modifiable lifestyle and psychological factors with lifetime CBP...
October 26, 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/27761665/somatosensory-brain-function-and-gray-matter-regional-volumes-differ-according-to-exercise-history-evidence-from-monozygotic-twins
#11
Pekka Hautasaari, Andrej M Savić, Otto Loberg, Eini Niskanen, Jaakko Kaprio, Urho M Kujala, Ina M Tarkka
Associations between long-term physical activity and cortical function and brain structure are poorly known. Our aim was to assess whether brain functional and/or structural modulation associated with long-term physical activity is detectable using a discordant monozygotic male twin pair design. Nine monozygotic male twin pairs were carefully selected for an intrapair difference in their leisure-time physical activity of at least three years duration (mean age 34 ± 1 years). We registered somatosensory mismatch response (SMMR) in EEG to electrical stimulation of fingers and whole brain MR images...
October 19, 2016: Brain Topography
https://www.readbyqxmd.com/read/27760663/-the-prognosis-of-monochorionic-co-twin-after-single-intrauterine-fetal-demise
#12
Y Wang, Y Wei, P B Yuan, X J Wang, Y Y Zhao
Objective: To analyze the prognosis of surviving monochorionic co-twin after single intrauterine fetal demise (sIUFD). Methods: Retrospectively analyzed the twin pregnancy cases admitted in Peking University Third Hospital between Jan 2008 and Feb 2015. We recorded perinatal characteristics, neuroimage in co-twin, and followed up the neonatal outcome. Results: 47 cases were found, including 45 cases of monochorionic diamniotic (MCDA) and 2 cases of monochorionic monoamniotic (MCMA). Median gestational age at sIUFD was 27 weeks...
October 11, 2016: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/27734240/sleep-disruption-chronotype-shift-work-and-prostate-cancer-risk-and-mortality-a-30-year-prospective-cohort-study-of-finnish-twins
#13
Barbra A Dickerman, Sarah C Markt, Markku Koskenvuo, Christer Hublin, Eero Pukkala, Lorelei A Mucci, Jaakko Kaprio
PURPOSE: Sleep disruption and shift work have been associated with cancer risk, but epidemiologic evidence for prostate cancer remains limited. We aimed to prospectively investigate the association between midlife sleep- and circadian-related parameters and later prostate cancer risk and mortality in a population-based cohort of Finnish twins. METHODS: Data were drawn from the Older Finnish Twin Cohort and included 11,370 twins followed from 1981 to 2012. Over the study period, 602 incident cases of prostate cancer and 110 deaths from prostate cancer occurred...
November 2016: Cancer Causes & Control: CCC
https://www.readbyqxmd.com/read/27734103/mitochondria-related-transcriptional-signature-is-downregulated-in-adipocytes-in-obesity-a-study-of-young-healthy-mz-twins
#14
Sini Heinonen, Maheswary Muniandy, Jana Buzkova, Adil Mardinoglu, Amaia Rodríguez, Gema Frühbeck, Antti Hakkarainen, Jesper Lundbom, Nina Lundbom, Jaakko Kaprio, Aila Rissanen, Kirsi H Pietiläinen
AIMS/HYPOTHESIS: Low mitochondrial activity in adipose tissue is suggested to be an underlying factor in obesity and its metabolic complications. We aimed to find out whether mitochondrial measures are downregulated in obesity also in isolated adipocytes. METHODS: We studied young adult monozygotic (MZ) twin pairs discordant (n = 14, intrapair difference ΔBMI ≥ 3 kg/m(2)) and concordant (n = 5, ΔBMI < 3 kg/m(2)) for BMI, identified from ten birth cohorts of 22- to 36-year-old Finnish twins...
January 2017: Diabetologia
https://www.readbyqxmd.com/read/27726479/death-of-one-twin-during-the-perinatal-period-an-interpretative-phenomenological-analysis
#15
Sarah Meaney, Paul Corcoran, Keelin O'Donoghue
BACKGROUND: Perinatal death is one of the most difficult bereavements due to the shock and profound grief experienced by parents. It has been established that such bereavement has a life-lasting impact. Twin pregnancy is associated with increased perinatal risk, with higher rates of perinatal mortality than in singleton pregnancy. OBJECTIVES: To date, few studies have examined the effect of the loss of one twin diagnosed with a congenital abnormality during pregnancy...
October 11, 2016: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/27723547/smoking-status-as-a-predictor-of-antidepressant-medication-use
#16
Tellervo Korhonen, Anu Ranjit, Annamari Tuulio-Henriksson, Jaakko Kaprio
BACKGROUND: Cigarette smoking and depression are major public health concerns, but longitudinal research on the association between smoking and antidepressant use is scarce. The purpose of this study was to investigate, whether smoking predicts antidepressant medication during a 10-year follow-up. METHODS: A questionnaire was administered to Finnish adult twins in 1990. Antidepressant prescription data during 1995-2004 were obtained from the register of the Finnish Social Insurance Institution and linked to the survey data...
September 27, 2016: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27702415/shared-genetic-factors-in-the-co-occurrence-of-depression-and-fatigue
#17
Elizabeth C Corfield, Nicholas G Martin, Dale R Nyholt
Depression and fatigue have previously been suggested to share an underlying genetic contribution. The present study aims to investigate and characterize the familiality and genetic relationship between depression and fatigue. The familiality of depression and fatigue was assessed by calculating relative risks, measured by the prevalence ratio, within 643 monozygotic (MZ) and 577 dizygotic (DZ) twin pairs. Bivariate twin modeling was utilized to assess the magnitude of shared heritability between depression and fatigue...
December 2016: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/27697135/risk-impact-of-having-a-first-degree-relative-with-affective-disorder-a-7-year-follow-up-study
#18
Maj Vinberg
This study investigated a high-risk sample in order to elucidate risk factors for affective disorder. Healthy monozygotic (MZ) and dizygotic (DZ) twins with and without a co-twin with a history of affective disorder were identified through nationwide registers. Two risk groups were identified: the high-risk group comprised twins at risk of developing affective disorder (DZ or MZ twin; index co-twin affected); the low risk group (control group) comprised twins at low risk of developing affective disorder (DZ or MZ twin; index co-twin not affected)...
October 2016: Danish Medical Journal
https://www.readbyqxmd.com/read/27641241/twin-studies-for-the-investigation-of-the-relationships-between-genetic-factors-and-brain-abnormalities-in-bipolar-disorder
#19
L Squarcina, C Fagnani, M Bellani, C A Altamura, P Brambilla
The pathogenesis of bipolar disorder (BD) is to date not entirely clear. Classical genetic research showed that there is a contribution of genetic factors in BD, with high heritability. Twin studies, thanks to the fact that confounding factors as genetic background or family environment are shared, allow etiological inferences. In this work, we selected twin studies, which focus on the relationship between BD, genetic factors and brain structure, evaluated with magnetic resonance imaging. All the studies found differences in brain structure between BD patients and their co-twins, and also in respect to healthy controls...
September 19, 2016: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/27634804/transcriptional-signatures-of-sleep-duration-discordance-in-monozygotic-twins
#20
Nathaniel F Watson, Dedra Buchwald, Jeff J Delrow, Willian A Altemeier, Michael V Vitiello, Allan I Pack, Mike Bamshad, Carolyn Noonan, Sina Gharib
INTRODUCTION: Habitual short sleep duration is associated with adverse metabolic, cardiovascular, and inflammatory effects. Co-twin study methodologies account for familial (e.g., genetics and shared environmental) confounding, allowing assessment of subtle environmental effects, such as the effect of habitual short sleep duration on gene expression. Therefore, we investigated gene expression in monozygotic twins discordant for actigraphically phenotyped habitual sleep duration. METHODS: Eleven healthy monozygotic twin pairs (82% female; mean age 42...
September 9, 2016: Sleep
keyword
keyword
49077
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"