keyword
MENU ▼
Read by QxMD icon Read
search

B17

keyword
https://www.readbyqxmd.com/read/28760138/age-standardized-mortality-rates-related-to-viral-hepatitis-in-brazil
#1
Hugo Perazzo, Antonio G Pacheco, Paula M Luz, Rodolfo Castro, Chris Hyde, Juliana Fittipaldi, Caroline Rigolon, Sandra W Cardoso, Beatriz Grinsztejn, Valdiléa G Veloso
BACKGROUND: Liver-related mortality has been increasing worldwide. We aimed to estimate the age-standardized mortality rates from viral hepatitis in Brazil. METHODS: The Brazilian National Death Registry was analyzed from 2008 to 2014. Viral hepatitis deaths were defined by the following ICD-10 codes in the death certificate: hepatitis A [B15.0; B15.9]; hepatitis B [B16.2; B16.9; B18.1]; hepatitis C [B17.1; B18.2]; hepatitis Delta [B16.0; B16.1; B18.0; B17.0] and other viral hepatitis [B17...
July 31, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28748842/separation-quantification-and-mosquito-larvicidal-activity-of-insecticidal-crystal-proteins-of-bacillus-thuringiensis-var-israelensis-vcrc-b17-mtcc-5596
#2
I Geetha, P Regnakumari, A M Manonmani
No abstract text is available yet for this article.
April 2017: Journal of Vector Borne Diseases
https://www.readbyqxmd.com/read/28732522/the-excretory-secretory-products-of-echinococcus-granulosus-protoscoleces-directly-regulate-the-differentiation-of-b10-b17-and-th17-cells
#3
Wei Pan, Wen-Ting Hao, Yu-Juan Shen, Xiang-Yang Li, Yan-Juan Wang, Fen-Fen Sun, Jian-Hai Yin, Jing Zhang, Ren-Xian Tang, Jian-Ping Cao, Kui-Yang Zheng
BACKGROUND: Excretory-secretory products (ESPs) released by helminths are well-known to regulate T cell responses in the host. However, their direct influence in the differentiation of naïve T cells, and especially B cells, remains largely unknown. This study investigated the effects of Echinococcus granulosus protoscoleces ESPs (EgPSC-ESPs) on the differentiation of IL-10-producing B cells (B10), IL-17A-producing B cells (B17) and Th17 cells. METHODS: BALB/c mice injected with EgPSC were used to evaluate the in vivo profiles of B10, B17 and Th17 cells...
July 21, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28566747/novel-locally-active-estrogens-accelerate-cutaneous-wound-healing-part-2
#4
Mario Brufani, Nicoletta Rizzi, Clara Meda, Luigi Filocamo, Francesca Ceccacci, Virginia D'Aiuto, Gabriele Bartoli, Angela La Bella, Luisa M Migneco, Rinaldo Marini Bettolo, Francesca Leonelli, Paolo Ciana, Adriana Maggi
Estrogen deprivation is associated with delayed healing, while estrogen replacement therapy (ERT) accelerates acute wound healing and protects against development of chronic wounds. However, current estrogenic molecules have undesired systemic effects, thus the aim of our studies is to generate new molecules for topic administration that are devoid of systemic effects. Following a preliminary study, the new 17β-estradiol derivatives 1 were synthesized. The estrogenic activity of these novel compounds was evaluated in vitro using the cell line ERE-Luc B17 stably transfected with an ERE-Luc reporter...
May 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28444425/pharmacogenetic-markers-to-predict-the-clinical-response-to-methotrexate-in-south-indian-tamil-patients-with-psoriasis
#5
S Indhumathi, Medha Rajappa, Laxmisha Chandrashekar, P H Ananthanarayanan, D M Thappa, V S Negi
INTRODUCTION: Despite the advent of several new systemic therapies, methotrexate remains the gold standard for the treatment of moderate to severe psoriasis. However, there exists a significant heterogeneity in individual response to methotrexate. There are no consistently reliable markers to predict methotrexate treatment response till date. OBJECTIVES: We aimed to demonstrate the association of certain genetic variants in the HLA (HLA-A2, HLA-B17, and HLA-Cw6) and the non-HLA genes including T-helper (Th)-1, Th-2, Th-17 cytokine genes (IFN-γ, IL-2, IL-4, IL-10, IL-12B, and IL-23R), and T-regulatory gene (FOXP3) with the methotrexate treatment response in South Indian Tamil patients with psoriasis...
August 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28300751/synthesis-and-evaluation-of-new-pyrazoline-derivatives-as-potential-anticancer-agents-in-hepg-2-cell-line
#6
Weijie Xu, Ying Pan, Hong Wang, Haiyan Li, Qing Peng, Duncan Wei, Cheng Chen, Jinhong Zheng
Cancer is a major public health concern worldwide. Adverse effects of cancer treatments still compromise patients' quality of life. To identify new potential anticancer agents, a series of novel pyrazoline derivatives were synthesized and evaluated for cytotoxic effects on HepG-2 (human liver hepatocellular carcinoma cell line) and primary hepatocytes. Compound structures were confirmed by ¹H-NMR, mass spectrometry, and infrared imaging. An in vitro assay demonstrated that several compounds exerted cytotoxicity in the micromolar range...
March 16, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28268063/human-escherichia-coli-isolates-from-hemocultures-septicemia-linked-to-urogenital-tract-infections-is-caused-by-isolates-harboring-more-virulence-genes-than-bacteraemia-linked-to-other-conditions
#7
COMPARATIVE STUDY
Lenka Micenková, Alžbeta Beňová, Lucia Frankovičová, Juraj Bosák, Martin Vrba, Alena Ševčíková, Marta Kmeťová, David Šmajs
Escherichia coli is the most common cause of bloodstream infections and community-acquired sepsis. The main aim of this study was to determine virulence characteristics of E. coli isolates from hemocultures of patients with a primary disease of urogenital tract, digestive system, a neoplastic blood disease, or other conditions. Results from a set of 314 E. coli isolates from hemocultures were compared to data from a previously published analysis of 1283 fecal commensal E. coli isolates. Genetic profiling of the 314 E...
April 2017: International Journal of Medical Microbiology: IJMM
https://www.readbyqxmd.com/read/28138769/molecular-and-virulence-characterization-of-toxoplasma-gondii-strains-isolated-from-humans-in-portugal
#8
Anabela Vilares, Maria João Gargaté, Idalina Ferreira, Susana Martins, João Paulo Gomes
Toxoplasma gondii is an apicomplexan parasite responsible for toxoplasmosis which infects all warm-blooded vertebrates, including mammals and birds. The majority of studies conducted in Europe have revealed that more than 80 % of strains isolated from human infections belong to genotype II, whereas genotypes I and III are responsible for a small number of cases. Atypical and recombinant strains are generally associated with more severe infections. In Portugal, there is a lack of data concerning genetic diversity as the classical typing studies in humans have never been performed...
March 2017: Parasitology Research
https://www.readbyqxmd.com/read/27807263/symbiodinium-biogeography-tracks-environmental-patterns-rather-than-host-genetics-in-a-key-caribbean-reef-builder-orbicella-annularis
#9
Emma V Kennedy, Linda Tonk, Nicola L Foster, Iliana Chollett, Juan-Carlos Ortiz, Sophie Dove, Ove Hoegh-Guldberg, Peter J Mumby, Jamie R Stevens
The physiological performance of a reef-building coral is a combined outcome of both the coral host and its algal endosymbionts, Symbiodinium While Orbicella annularis-a dominant reef-building coral in the Wider Caribbean-is known to be a flexible host in terms of the diversity of Symbiodinium types it can associate with, it is uncertain how this diversity varies across the Caribbean, and whether spatial variability in the symbiont community is related to either O. annularis genotype or environment. Here, we target the Symbiodinium-ITS2 gene to characterize and map dominant Symbiodinium hosted by O...
November 16, 2016: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/27805301/effect-of-ugt2b17-deletion-polymorphism-on-prognosis-in-pediatric-cancer
#10
Sae Ishimaru, Yuki Yuza, Takashi Kaneko, Mitsuyoshi Urashima
BACKGROUND: UDP-glucuronosyltransferase 2 family, polypeptide B17 (UGT2B17) encodes for an enzyme that modifies carcinogens, C19 steroids, xenobiotics, and anticancer chemotherapeutic agents by glucuronidation. Pediatric cancers are much more sensitive to anticancer agents than adult cancers. The aim of this study was therefore to examine the effects of UGT2B17 deletion polymorphism on prognosis in pediatric cancer. METHODS: A total of 145 DNA samples were collected from children with malignant disease...
November 2, 2016: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/27678116/cellulose-synthesis-by-komagataeibacter-rhaeticus-strain-p-1463-isolated-from-kombucha
#11
Pavels Semjonovs, Maija Ruklisha, Longina Paegle, Madara Saka, Rita Treimane, Marite Skute, Linda Rozenberga, Laura Vikele, Martins Sabovics, Ilse Cleenwerck
Isolate B17 from Kombucha was estimated to be an efficient producer of bacterial cellulose (BC). The isolate was deposited under the number P 1463 and identified as Komagataeibacter rhaeticus by comparing a generated amplified fragment length polymorphism (AFLP™) DNA fingerprint against a reference database. Static cultivation of the K. rhaeticus strain P 1463 in Hestrin and Schramm (HS) medium resulted in 4.40 ± 0.22 g/L BC being produced, corresponding to a BC yield from glucose of 25.30 ± 1.78 %, when the inoculum was made with a modified HS medium containing 10 g/L glucose...
February 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/27646192/human-extraintestinal-pathogenic-escherichia-coli-strains-differ-in-prevalence-of-virulence-factors-phylogroups-and-bacteriocin-determinants
#12
Lenka Micenková, Juraj Bosák, Martin Vrba, Alena Ševčíková, David Šmajs
BACKGROUND: The study used a set of 407 human extraintestinal pathogenic E. coli strains (ExPEC) isolated from (1) skin and soft tissue infections, (2) respiratory infections, (3) intra-abdominal infections, and (4) genital smears. The set was tested for bacteriocin production, for prevalence of bacteriocin and virulence determinants, and for phylogenetic typing. Results obtained from the group of ExPEC strains were compared to data from our previously published analyses of 1283 fecal commensal E...
2016: BMC Microbiology
https://www.readbyqxmd.com/read/27463367/the-quest-for-the-shortest-fragments-of-a-13-19-and-b-12-17-responsible-for-the-aggregation-of-human-insulin
#13
Monika Swiontek, Kamil Rozniakowski, Justyna Fraczyk, Wojciech Lipinski, Krystian Galecki, Stanislaw Wysocki, Bertrand G R Dupont, Zbigniew J Kaminski, Beata Kolesinska
AIM: To identify the shortest components of A13-A19, B12-B17 fragments capable for fibrillation and to validate the dependability of aggregation on the presence of hydroxyl group engaged in the 'tyrosine kissing'. MATERIALS & METHODS: Fragments A13-A19 and B12-B17 of insulin and all shortened analogues were obtained by using DMT/NMM/TosO(-) as a coupling reagent. The aggregation was studied by three independent tests. RESULTS: Studies on the susceptibility to aggregation of truncated analogs of insulin amyloidogenic core show three groups of peptides...
August 2016: Nanomedicine
https://www.readbyqxmd.com/read/27272399/polyoxypregnane-glycosides-from-the-roots-of-marsdenia-tenacissima-and-their-anti-hiv-activities
#14
Xu Pang, Li-Ping Kang, Xiao Mei Fang, Yang Zhao, He-Shui Yu, Li-Feng Han, Hai-Tao Li, Li-Xia Zhang, Bao-Lin Guo, Li-Yan Yu, Bai-Ping Ma
A continuous phytochemical study on the roots of Marsdenia tenacissima led to the isolation and identification of 13 new polyoxypregnane glycosides named marstenacissides B10-B17 (1, 2, 4, 7, 8, 11, 12, and 14) and marstenacissides A8-A12 (3, 9, 10, 13, and 15) in addition to two known polyoxypregnane glycosides marsdenosides M and L (5 and 6). Their structures were established by spectroscopic techniques and by comparison with the reported data in the literature. Moreover, the anti-HIV activities of these isolates and the previous isolated marstenacissides A1-A7 and B1-B9 were assessed, some of which exhibited slight or negligible effects against HIV-1...
January 2017: Planta Medica
https://www.readbyqxmd.com/read/27066039/genomic-analysis-of-storage-protein-deficiency-in-genetically-related-lines-of-common-bean-phaseolus-vulgaris
#15
Sudhakar Pandurangan, Marwan Diapari, Fuqiang Yin, Seth Munholland, Gregory E Perry, B Patrick Chapman, Shangzhi Huang, Francesca Sparvoli, Roberto Bollini, William L Crosby, Karl P Pauls, Frédéric Marsolais
A series of genetically related lines of common bean (Phaseolus vulgaris L.) integrate a progressive deficiency in major storage proteins, the 7S globulin phaseolin and lectins. SARC1 integrates a lectin-like protein, arcelin-1 from a wild common bean accession. SMARC1N-PN1 is deficient in major lectins, including erythroagglutinating phytohemagglutinin (PHA-E) but not α-amylase inhibitor, and incorporates also a deficiency in phaseolin. SMARC1-PN1 is intermediate and shares the phaseolin deficiency. Sanilac is the parental background...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/26882892/analysis-of-root-knot-nematode-and-fusarium-wilt-disease-resistance-in-cotton-gossypium-spp-using-chromosome-substitution-lines-from-two-alien-species
#16
M Ulloa, C Wang, S Saha, R B Hutmacher, D M Stelly, J N Jenkins, J Burke, P A Roberts
Chromosome substitution (CS) lines in plants are a powerful genetic resource for analyzing the contribution of chromosome segments to phenotypic variance. In this study, a series of interspecific cotton (Gossypium spp.) CS lines were used to identify a new germplasm resource, and to validate chromosomal regions and favorable alleles associated with nematode or fungal disease resistance traits. The CS lines were developed in the G. hirsutum L. TM-1 background with chromosome or chromosome segment substitutions from G...
April 2016: Genetica
https://www.readbyqxmd.com/read/26809981/brucella-pinnipedialis-in-hooded-seal-cystophora-cristata-primary-epithelial-cells
#17
Anett Kristin Larsen, Jacques Godfroid, Ingebjørg Helena Nymo
BACKGROUND: Marine Brucella spp. have been isolated from numerous pinniped and cetacean species, but pathological findings in association with infection with Brucella pinnipedialis in pinnipeds have been sparse. The capacity of brucellae to survive and replicate within host macrophages underlies their important ability to produce chronic infections, but previous work has shown that B. pinnipedialis spp. are rapidly eliminated from hooded seal (Cystophora cristata) alveolar macrophages...
January 25, 2016: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/26526977/comparison-and-analysis-of-the-prevalence-of-hepatitis-c-virus-infection-by-region-in-the-republic-of-korea-during-2005-2012
#18
COMPARATIVE STUDY
Hae-Sook Shon, Hwa Young Choi, Jang Rak Kim, So Yeon Ryu, Youn-Jae Lee, Myeong Jin Lee, Hyun Ju Min, Jun Lee, Yeong Jun Song, Moran Ki
BACKGROUND/AIMS: This study compared the prevalence of hepatitis C virus (HCV) infection in the Republic of Korea and estimated the high-risk regions and towns. METHODS: National Health Insurance Service data for 8 years from 2005 to 2012 were used. The subjects of the study had visited medical facilities and been diagnosed with or received treatment for acute or chronic HCV as a primary or secondary disease according to ICD-10 codes of B17.1 or B18.2, respectively...
September 2015: Clinical and Molecular Hepatology
https://www.readbyqxmd.com/read/26462797/the-genomic-landscape-of-ribosomal-peptides-containing-thiazole-and-oxazole-heterocycles
#19
Courtney L Cox, James R Doroghazi, Douglas A Mitchell
BACKGROUND: Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a burgeoning class of natural products with diverse activity that share a similar origin and common features in their biosynthetic pathways. The precursor peptides of these natural products are ribosomally produced, upon which a combination of modification enzymes installs diverse functional groups. This genetically encoded peptide-based strategy allows for rapid diversification of these natural products by mutation in the precursor genes merged with unique combinations of modification enzymes...
October 13, 2015: BMC Genomics
https://www.readbyqxmd.com/read/26418648/fly-ash-based-bacillus-thuringiensis-var-israelensis-formulation-for-use-against-culex-quinquefasciatus-the-vector-of-filariasis-in-natural-ecosystems
#20
S Tamilselvan, P Jambulingam, V Manoharan, R Shanmugasundaram, G Vivekanandan, A M Manonmani
BACKGROUND & OBJECTIVES: Fly ash is produced in huge quantities by the various thermal power stations in India. This thermal waste has been employed as a carrier material in the preparation of a biopesticidal water dispersible powder (WDP) formulation for use against mosquitoes. In the present investigation, this newly developed fly ash based WDP formulation was evaluated in natural breeding habitats of mosquito. METHODS: Fly ash based WDP formulation of Bacillus thuringiensis var...
September 2015: Journal of Vector Borne Diseases
keyword
keyword
49063
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"