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Effectiveness of applied behavior analysis

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https://www.readbyqxmd.com/read/28435033/could-reduced-fluid-intake-cause-the-placebo-effect-seen-in-overactive-bladder-clinical-trials-analysis-of-a-large-solifenacin-integrated-database
#1
Sender Herschorn, Christopher R Chapple, Robert Snijder, Emad Siddiqui, Linda Cardozo
OBJECTIVE To assess the hypothesis that patients receiving placebo in overactive bladder (OAB) trials who experience less benefit from 'treatment' continue with behavioral modifications such as fluid restriction, whereas those on active treatment adopt more normal drinking patterns. This may manifest itself as a reduction in micturition frequency (MF). MATERIALS AND METHODS We interrogated a large integrated database containing pooled patient data from 4 randomized, placebo-controlled phase III OAB solifenacin studies...
April 20, 2017: Urology
https://www.readbyqxmd.com/read/28431305/cognitive-behavioral-high-parental-involvement-treatments-for-pediatric-obsessive-compulsive-disorder-a-meta-analysis
#2
REVIEW
Marina Iniesta-Sepúlveda, Ana I Rosa-Alcázar, Julio Sánchez-Meca, José L Parada-Navas, Ángel Rosa-Alcázar
A meta-analysis on the efficacy of cognitive-behavior-family treatment (CBFT) on children and adolescents with obsessive-compulsive disorder (OCD) was accomplished. The purposes of the study were: (a) to estimate the effect magnitude of CBFT in ameliorating obsessive-compulsive symptoms and reducing family accommodation on pediatric OCD and (b) to identify potential moderator variables of the effect sizes. A literature search enabled us to identify 27 studies that fulfilled our selection criteria. The effect size index was the standardized pretest-postest mean change index...
April 4, 2017: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/28429592/peptide-retention-time-prediction-in-hydrophilic-interaction-liquid-chromatography-data-collection-methods-and-features-of-additive-and-sequence-specific-models
#3
Oleg V Krokhin, Peyman Ezzati, Vic Spicer
The development of a peptide retention prediction model for hydrophilic interaction liquid chromatography (XBridge Amide column) is described for a collection of ~40,000 tryptic peptides. Off-line 2D LC-MS/MS analysis (HILIC-RPLC) of S. cerevisiae whole cell lysate has been used to acquire retention information for a HILIC separation. The large size of the optimization dataset (more than two orders of magnitude compared to previous reports) permits the accurate assignment of hydrophilic retention coefficients of individual amino acids, establishing both, the effects of amino-acid position relative to peptide termini and the influence of peptide secondary structure in HILIC...
April 21, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28427363/a-spatio-temporal-analysis-of-suicide-in-el-salvador
#4
Carlos Carcach
BACKGROUND: In 2012, international statistics showed El Salvador's suicide rate as 40th in the world and the highest in Latin America. Over the last 15 years, national statistics show the suicide death rate declining as opposed to an increasing rate of homicide. Though completed suicide is an important social and health issue, little is known about its prevalence, incidence, etiology and spatio-temporal behavior. The primary objective of this study was to examine completed suicide and homicide using the stream analogy to lethal violence within a spatio-temporal framework...
April 20, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28424638/the-acquisition-of-orthographic-knowledge-evidence-from-the-lexicality-effects-on-n400
#5
Yu-Lin Tzeng, Chun-Hsien Hsu, Yu-Chen Huang, Chia-Ying Lee
This study aimed to understand how reading ability shapes the lexicality effects on N400. Fifty-three typical developing children from the second to the sixth grades were asked to perform the pronounceability judgment task on a set of Chinese real characters (RC), pseudocharacters (PC) and non-characters (NC), as ERPs were recorded. The cluster-based permutation analysis revealed that children with low- to medium-reading ability showed greater negativity to NCs than to RCs and PCs in frontal sites from 300 to 450 ms, while children with high ability group showed a greater positivity to NCs than both RCs and PCs at central to posterior sites...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28422667/modeling-and-analysis-of-beta-oscillations-in-the-basal-ganglia
#6
Chen Liu, Jiang Wang, Huiyan Li, Chris Fietkiewicz, Kenneth A Loparo
Enhanced beta (12-30 Hz) oscillatory activity in the basal ganglia (BG) is a prominent feature of the Parkinsonian state in animal models and in patients with Parkinson's disease. Increased beta oscillations are associated with severe dopaminergic striatal depletion. However, the mechanisms underlying these pathological beta oscillations remain elusive. Inspired by the experimental observation that only subsets of neurons within each nucleus in the BG exhibit oscillatory activities, a computational model of the BG-thalamus neuronal network is proposed, which is characterized by subdivided nuclei within the BG...
April 12, 2017: IEEE Transactions on Neural Networks and Learning Systems
https://www.readbyqxmd.com/read/28419951/can-fractal-methods-applied-to-video-tracking-detect-the-effects-of-deltamethrin-pesticide-or-mercury-on-the-locomotion-behavior-of-shrimps
#7
Bruno Mendes Tenorio, Eurípedes Alves da Silva Filho, Gentileza Santos Martins Neiva, Valdemiro Amaro da Silva, Fernanda das Chagas Angelo Mendes Tenorio, Themis de Jesus da Silva, Emerson Carlos Soares E Silva, Romildo de Albuquerque Nogueira
Shrimps can accumulate environmental toxicants and suffer behavioral changes. However, methods to quantitatively detect changes in the behavior of these shrimps are still needed. The present study aims to verify whether mathematical and fractal methods applied to video tracking can adequately describe changes in the locomotion behavior of shrimps exposed to low concentrations of toxic chemicals, such as 0.15µgL(-1) deltamethrin pesticide or 10µgL(-1) mercuric chloride. Results showed no change after 1min, 4, 24, and 48h of treatment...
April 15, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28419471/spectral-analysis-of-the-stick-slip-phenomenon-in-oral-tribological-texture-evaluation
#8
Solange Sanahuja, Rutuja Upadhyay, Heiko Briesen, Jianshe Chen
"Oral" tribology has become a new paradigm in food texture studies to understand complex texture attributes, such as creaminess, oiliness, and astringency, which could not be successfully characterized by traditional texture analysis nor by rheology. Stick-slip effects resulting from intermittent sliding motion during kinetic friction of oral mucosa could constitute an additional determining factor of sensory perception where traditional friction coefficient values and their Stribeck regimes fail in predicting different lubricant (food bolus and saliva) behaviors...
March 28, 2017: Journal of Texture Studies
https://www.readbyqxmd.com/read/28418398/intranasal-oxytocin-enhances-intrinsic-corticostriatal-functional-connectivity-in-women
#9
R A I Bethlehem, M V Lombardo, M-C Lai, B Auyeung, S K Crockford, J Deakin, S Soubramanian, A Sule, P Kundu, V Voon, S Baron-Cohen
Oxytocin may influence various human behaviors and the connectivity across subcortical and cortical networks. Previous oxytocin studies are male biased and often constrained by task-based inferences. Here, we investigate the impact of oxytocin on resting-state connectivity between subcortical and cortical networks in women. We collected resting-state functional magnetic resonance imaging (fMRI) data on 26 typically developing women 40 min following intranasal oxytocin administration using a double-blind placebo-controlled crossover design...
April 18, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28413061/mechanical-behavior-of-bulk-direct-composite-versus-block-composite-and-lithium-disilicate-indirect-class-ii-restorations-by-cad-fem-modeling
#10
Pietro Ausiello, Stefano Ciaramella, Andrea Fabianelli, Antonio Gloria, Massimo Martorelli, Antonio Lanzotti, David C Watts
OBJECTIVES: To study the influence of resin based and lithium disilicate materials on the stress and strain distributions in adhesive class II mesio-occlusal-distal (MOD) restorations using numerical finite element analysis (FEA). To investigate the materials combinations in the restored teeth during mastication and their ability to relieve stresses. METHODS: One 3D model of a sound lower molar and three 3D class II MOD cavity models with 95° cavity-margin-angle shapes were modelled...
April 13, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28412561/metastatic-human-breast-cancer-to-the-spine-produces-mechanical-hyperalgesia-and-gait-deficits-in-rodents
#11
Rachel Sarabia-Estrada, Alejandro Ruiz-Valls, Hugo Guerrero-Cazares, Ana M Ampuero, Ismael Jimenez-Estrada, Samantha De Silva, Lydia J Bernhardt, C Rory Goodwin, A Karim Ahmed, Yuxin Li, Neil A Phillips, Ziya L Gokaslan, Alfredo Quiñones-Hinojosa, Daniel M Sciubba
BACKGROUND CONTEXT: Metastases to the spine are a common source of severe pain in cancer patients. The secondary effects of spinal metastases include pain, bone fractures, hypercalcemia, and neurological deficits. As the disease progresses, pain severity can increase until it becomes refractory to medical treatments and leads to a decreased quality of life for patients. A key obstacle in the study of pain-induced spinal cancer is the lack of reliable and reproducible spine cancer animal models...
April 13, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28406228/electrokinetic-instability-in-microchannel-ferrofluid-water-co-flows
#12
Le Song, Liandong Yu, Yilong Zhou, Asher Reginald Antao, Rama Aravind Prabhakaran, Xiangchun Xuan
Electrokinetic instability refers to unstable electric field-driven disturbance to fluid flows, which can be harnessed to promote mixing for various electrokinetic microfluidic applications. This work presents a combined numerical and experimental study of electrokinetic ferrofluid/water co-flows in microchannels of various depths. Instability waves are observed at the ferrofluid and water interface when the applied DC electric field is beyond a threshold value. They are generated by the electric body force that acts on the free charge induced by the mismatch of ferrofluid and water electric conductivities...
April 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28404688/brain-disposition-of-cis-para-methyl-4-methylaminorex-cis-4-4-dmar-and-its-potential-metabolites-after-acute-and-chronic-treatment-in-rats-correlation-with-central-behavioral-effects
#13
Jacopo Lucchetti, Claudio Marcello Marzo, Alice Passoni, Angelo Di Clemente, Federico Moro, Renzo Bagnati, Marco Gobbi, Luigi Cervo
Para-methyl-4-methylaminorex (4,4'-DMAR) is a phenethylamine derivative with psychostimulant activity, whose abuse has been associated with several deaths and a wide range of adverse effects. We recently validated an HPLC-MS/MS method to measure the compound's concentrations in plasma, and applied it to describe the pharmacokinetic properties after single dose in rats. In this study we investigated the brain disposition and metabolism of cis-4,4'-DMAR after intraperitoneal injection, and its central behavioral effects...
April 12, 2017: Journal of Pharmacology and Experimental Therapeutics
https://www.readbyqxmd.com/read/28402208/a-dynamic-approach-for-outpatient-scheduling
#14
James Creps, Vahid Lotfi
AIMS: Patient no-show is a recurrent problem in medical centers and, in conjunction with cancellation of appointments, often results in loss of productivity and excessive patient time to appointment. The purpose of this study was to develop a dynamic procedure for scheduling patients within an outpatient clinic where patients are expected to have multiple appointments, such as physical therapy, occupational therapy, primary care, and dentistry. METHODS: This retrospective study involved the year 2014 de-identified patient records from an outpatient clinic affiliated with a large university hospital...
April 12, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28398986/living-with-symptoms-of-attention-deficit-hyperactivity-disorder-in-adulthood-a-systematic-review-of-qualitative-evidence
#15
Merete B Bjerrum, Preben U Pedersen, Palle Larsen
BACKGROUND: Attention deficit hyperactivity disorder (ADHD) relates to four dimensions of behavior: inattentiveness, restlessness, impulsiveness and hyperactivity. Symptoms affect multiple areas of daily life such as academic performance and social functioning. Despite the negative effects of ADHD, people diagnosed with ADHD do not necessarily regard themselves as being impaired. However, it is unclear how adults with ADHD experience and manage their symptoms. OBJECTIVES: To identify and synthesize the best available evidence on how adults experience living with ADHD...
April 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28394854/a-role-for-nk-1-neurons-in-the-rostral-ventromedial-medulla-in-the-development-of-chronic-post-thoracotomy-pain
#16
Sergey G Khasabov, Jeffrey Chi-Fei Wang, Donald A Simone, Gary R Strichartz
Thoracotomy results in chronic post-operative pain (CPTP) in half of the cases. Earlier findings in rat models of persistent post-surgical pain suggest that spinal pathways are critical for pain onset but not its maintenance. Descending systems from the brain stem modulate nociceptive transmission in the spinal cord and contribute to persistent pain, but their role in chronic postoperative pain has not been studied. Here we ablated pronociceptive neurokinin-1 receptor (NK-1R)-expressing neurons in the rat rostral ventromedial medulla (RVM) to identify their role in CPTP...
April 5, 2017: Pain
https://www.readbyqxmd.com/read/28392141/clinician-parent-discussions-about-influenza-vaccination-of-children-and-their-association-with-vaccine-acceptance
#17
Annika M Hofstetter, Jeffrey D Robinson, Katherine Lepere, Morgan Cunningham, Nicole Etsekson, Douglas J Opel
OBJECTIVE: To examine how clinicians communicate with parents about influenza vaccination and the effect of these communication behaviors on parental vaccine decision-making. STUDY DESIGN: We performed a secondary analysis of data obtained from a cross-sectional observational study in which health supervision visits between pediatric clinicians and English-speaking parents of young children were videotaped. Eligible visits occurred during the 2011-2012 and 2013-2014 influenza seasons, included children ≥6months, and contained an influenza vaccine discussion...
May 9, 2017: Vaccine
https://www.readbyqxmd.com/read/28391964/associations-between-fathers-and-sons-sexual-risk-in-rural-kenya-the-potential-for-intergenerational-transmission
#18
Ali M Giusto, Eric P Green, Eve S Puffer
PURPOSE: Despite high rates of HIV in areas of Sub-Saharan Africa and men's role in driving the epidemic, little is known about whether or how sexual risk-both behaviors and beliefs-may be passed down through generations of males. This study examined associations between sexual risk behaviors and sex-related beliefs of adolescent males and those of their male caregivers in Kenya, as well as the potential moderating effects of parenting characteristics and father-son relationship quality...
April 5, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28391829/electrochemical-behavior-and-voltammetric-detection-of-fenitrothion-based-on-a-pencil-graphite-electrode-modified-with-reduced-graphene-oxide-rgo-poly-e-1-4-4-phenylamino-phenyl-diazenyl-phenyl-ethanone-dpa-composite-film
#19
Ozge Surucu, Gulcin Bolat, Serdar Abaci
A combination of a novel synthesized azo dye (E)-1-(4-((4-(phenylamino)phenyl)diazenyl) phenyl)ethanone and reduced graphene oxide was used to electrochemically modify the surface of a pencil graphite electrode. The surfaces of the modified electrodes were characterized using electrochemical techniques (cyclic voltammetry and electrochemical impedance spectroscopy) and spectroscopic techniques (scanning electron microscopy and attenuated total reflectance). This azo dye/reduced graphene oxide modified electrode was applied first time for the electrochemical detection of an organophosphorus pesticide, fenitrothion...
June 1, 2017: Talanta
https://www.readbyqxmd.com/read/28388519/occurrence-sources-and-human-exposure-assessment-of-sccps-in-indoor-dust-of-northeast-china
#20
Li-Hua Liu, Wan-Li Ma, Li-Yan Liu, Chun-Yan Huo, Wen-Long Li, Chong-Jing Gao, Hai-Ling Li, Yi-Fan Li, Hing Man Chan
Short-chain chlorinated paraffins (SCCPs) are widely used chemicals in household products and might cause adverse human health effects. However, limited information is available on the occurrence of SCCPs in indoor environments and their exposure risks on humans. In this study the concentrations, profiles and human exposure of SCCPs in indoor dust from five different indoor environments, including commercial stores, residential apartments, dormitories, offices and laboratories were characterized. The SCCPs levels ranged from 10...
April 4, 2017: Environmental Pollution
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