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Stimulus equivalence

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https://www.readbyqxmd.com/read/29303841/mirror-imaging-of-finger-mechanical-stimulation-affects-secondary-somatosensory-response
#1
Kazuyoshi Nakanishi, Tomoshi Watanabe, Toru Sunagawa, Hiroshi Kurumadani, Hanan Abd El-Rahman, Mitsuo Ochi, Nobuo Adachi
The aim of this study was to investigate the effect of finger-tip touch on the somatosensory cortex under mirror imaging conditions. Magnetoencephalographic recordings of somatosensory-evoked field responses to mechanical tactile stimulation of the index finger in both hands were obtained for the right-handed healthy participants as part of the following mirror or nonmirror tasks. Both hands were screened and mechanical stimuli were delivered to the right index finger pulp. A mirror was placed in front of the patient with the right hand facing the reflective surface, as if it were the left side (mirror task)...
January 4, 2018: Neuroreport
https://www.readbyqxmd.com/read/29289578/developing-a-novel-preparation-to-analyze-the-onset-of-derived-stimulus-relations
#2
Adam H Doughty, Casey M Irwin
The experimental analysis of derived stimulus relations is a critical research area. A training-then-testing preparation nearly always is used to study derived relations. In the training phase, participants learn the relevant baseline discriminations via differential consequences (e.g., AB and AC relations). In the testing phase, they are presented with probe trials in the absence of differential consequences (e.g., BA and CA symmetry trials and BC and CB equivalence trials). High accuracy levels sometimes are observed from the start of testing such that it is unclear whether the participants learned these relations before testing...
December 28, 2017: Behavioural Processes
https://www.readbyqxmd.com/read/29284554/representation-of-time-interval-entrained-by-periodic-stimuli-in-the-visual-thalamus-of-pigeons
#3
Yan Yang, Qian Wang, Shu-Rong Wang, Yi Wang, Qian Xiao
Animals use the temporal information from previously experienced periodic events to instruct their future behaviors. The retina and cortex are involved in such behavior, but it remains largely unknown how the thalamus, transferring visual information from the retina to the cortex, processes the periodic temporal patterns. Here we report that the luminance cells in the nucleus dorsolateralis anterior thalami (DLA) of pigeons exhibited oscillatory activities in a temporal pattern identical to the rhythmic luminance changes of repetitive light/dark (LD) stimuli with durations in the seconds-to-minutes range...
December 29, 2017: ELife
https://www.readbyqxmd.com/read/29283605/cognates-facilitate-switches-and-then-confusion-contrasting-effects-of-cascade-versus-feedback-on-language-selection
#4
Chuchu Li, Tamar H Gollan
The current study investigated the hypothesis that cognates (i.e., translation equivalents that overlap in form, e.g., lemon is limón in Spanish) facilitate language switches. Spanish-English bilinguals were cued to switch languages while repeatedly naming pictures with cognate versus noncognate names in separate (Experiment 1) or mixed (Experiments 2 and 3) blocks. In all 3 experiments, on the first presentation of each picture, cognates elicited significantly smaller switch costs and were produced faster than noncognates only on switch trials...
December 28, 2017: Journal of Experimental Psychology. Learning, Memory, and Cognition
https://www.readbyqxmd.com/read/29248857/catechol-o-methyltransferase-comt-genotype-affects-cognitive-control-during-total-sleep-deprivation
#5
Brieann C Satterfield, John M Hinson, Paul Whitney, Michelle A Schmidt, Jonathan P Wisor, Hans P A Van Dongen
Adaptive decision making is profoundly impaired by total sleep deprivation (TSD). This suggests that TSD impacts fronto-striatal pathways involved in cognitive control, where dopamine is a key neuromodulator. In the prefrontal cortex (PFC), dopamine is catabolized by the enzyme catechol-O-methyltransferase (COMT). A functional polymorphism (Val158Met) influences COMT's enzymatic activity, resulting in markedly different levels of prefrontal dopamine. We investigated the effect of this polymorphism on adaptive decision making during TSD...
November 26, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29247498/impact-of-high-intensity-interval-training-and-moderate-intensity-continuous-training-on-resting-and-post-exercise-cardiac-troponin-t-concentration
#6
Jinlei Nie, Haifeng Zhang, Zhaowei Kong, Keith George, Jonathan P Little, Tomas K Tong, Feifei Li, Qingde Shi
We evaluated the influence of 12 weeks high-intensity interval training (HIIT, repeated 4-min cycling at 90% V̇O2max interspersed with 3-min rest, 200-300 KJ/session, 3-4 days wk-1 ) and work-equivalent moderate-intensity continuous training (MICT, continuous cycling at 60% V̇O2max ) on resting cardiac troponin T (cTnT) as well as exercise-induced cTnT appearance. Forty-eight sedentary obese young women were randomly assigned to HIIT, MICT, or a control group. V̇O2max and body composition were measured before and after training...
December 16, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/29238967/potent-anti-inflammatory-and-pro-resolving-effects-of-anabasum-in-a-human-model-of-self-resolving-acute-inflammation
#7
Madhur P Motwani, Frances Bennett, Paul C Norris, Alexander A Maini, Marc J George, Justine Newson, Alice Henderson, Adrian J Hobbs, Mark Tepper, Barbara White, Charles N Serhan, Raymond MacAllister, Derek W Gilroy
Anabasum is a synthetic analogue of Δ8 - tetrahydrocannabinol (THC)-11-oic acid that in pre-clinical models of experimental inflammation exerts potent anti-inflammatory actions with minimal CNS cannabimimetic activity. Here we used a novel model of acute inflammation driven by i.d. UV-killed E. coli in healthy humans and found that Anabasum (5mg) exerted a potent anti-inflammatory effect equivalent to that of prednisolone in terms of inhibiting neutrophil infiltration, the hallmark of acute inflammation. These effects arose from the inhibition of the neutrophil chemoattractant LTB4 , while the inhibition of anti-phagocytic prostanoids (PGE2 , TxB2 and PGF2 α) resulted in enhanced clearance of inflammatory stimulus from the injected site...
December 14, 2017: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29222729/coding-of-time-dependent-stimuli-in-homogeneous-and-heterogeneous-neural-populations
#8
Manuel Beiran, Alexandra Kruscha, Jan Benda, Benjamin Lindner
We compare the information transmission of a time-dependent signal by two types of uncoupled neuron populations that differ in their sources of variability: i) a homogeneous population whose units receive independent noise and ii) a deterministic heterogeneous population, where each unit exhibits a different baseline firing rate ('disorder'). Our criterion for making both sources of variability quantitatively comparable is that the interspike-interval distributions are identical for both systems. Numerical simulations using leaky integrate-and-fire neurons unveil that a non-zero amount of both noise or disorder maximizes the encoding efficiency of the homogeneous and heterogeneous system, respectively, as a particular case of suprathreshold stochastic resonance...
December 8, 2017: Journal of Computational Neuroscience
https://www.readbyqxmd.com/read/29182669/nkt-cells-contribute-to-basal-il-4-production-but-are-not-required-to-induce-experimental-asthma
#9
Christopher G McKnight, Suzanne C Morris, Charles Perkins, Zhenqi Zhu, David A Hildeman, Albert Bendelac, Fred D Finkelman
CD1d-deficiency results in a selective deletion of NKT cells in mice that is reported to prevent murine allergic airway disease (AAD). Because we find 2-3 fold lower basal IL-4 production in CD1d- mice than in wild-type (WT) mice, we hypothesized that the contribution made by NKT cells to AAD would depend on the strength of the stimulus used to induce the disease. Consequently, we compared CD1d-deficient mice to WT mice in the development of AAD, using several models of disease induction that differed in the type and dose of allergen, the site of sensitization and the duration of immunization...
2017: PloS One
https://www.readbyqxmd.com/read/29162458/electrophysiological-impact-of-multiple-concussions-in-asymptomatic-athletes-a-re-analysis-based-on-alpha-activity-during-a-visual-spatial-attention-task
#10
Samuel Guay, Louis De Beaumont, Brandi Lee Drisdelle, Jean-Marc Lina, Pierre Jolicoeur
Most EEG studies used event-related potentials to assess long-term and cumulative effects of sport-related concussions on brain activity. Time-frequency methods provide another approach that allows the detection of subtle shifts in types and patterns of brain oscillations. We sought to discover whether event-related alpha activity would be significantly affected in asymptomatic multi-concussed athletes. We measured the amplitude of alpha activity (8-12Hz) from the EEG recorded during a visual-spatial attention task to compare event-related alpha perturbations in 13 multi-concussed athletes and 14 age-equivalent, non-concussed teammates...
November 21, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/29156142/cutaneous-vasomotor-adaptation-following-repeated-isothermal-heat-exposures-evidence-of-adaptation-specificity
#11
Sean R Notley, Elizabeth A Taylor, Norikazu Ohnishi, Nigel A S Taylor
Unequivocal enhancement of cutaneous vasomotor function has yet to be demonstrated following heat acclimation, possibly because the adaptation stimulus was not sustained, or because thermoeffector function was not assessed at equivalent deep-body temperatures. Therefore, forearm and local cutaneous vascular conductances were evaluated during exercise eliciting matched deep-body temperatures (37.5oC, 38.5oC), before and after isothermal heat acclimation. Both indices increased (21% and 25%), confirming cutaneous vasomotor adaptation can occur, provided those experimental design specifications are satisfied...
November 20, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29134296/p300-based-acuity-estimation-in-imitated-amblyopia
#12
Marvin L Beusterien, Sven P Heinrich
PURPOSE: A frequent approach to estimating visual acuity objectively is the recording of visual evoked potentials (VEPs) to patterns of different coarseness. This, however, overestimates acuity in patients with fragmented and distorted vision such as in amblyopia. This is likely due to VEP-based techniques using checkerboard or grating stimuli. We hypothesized that no overestimation would occur when the event-related potential P300 in response to optotype stimuli is used for acuity estimation...
November 13, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/29101523/functional-comparison-of-corticostriatal-and-thalamostriatal-postsynaptic-responses-in-striatal-neurons-of-the-mouse
#13
M A Arias-García, D Tapia, J A Laville, V M Calderón, Y Ramiro-Cortés, J Bargas, E Galarraga
Synaptic inputs from cortex and thalamus were compared in electrophysiologically defined striatal cell classes: direct and indirect pathways' striatal projection neurons (dSPNs and iSPNs), fast-spiking interneurons (FS), cholinergic interneurons (ChINs), and low-threshold spiking-like (LTS-like) interneurons. Our purpose was to observe whether stimulus from cortex or thalamus had equivalent synaptic strength to evoke prolonged suprathreshold synaptic responses in these neuron classes. Subthreshold responses showed that inputs from either source functionally mix up in their dendrites at similar electrotonic distances from their somata...
November 3, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/29093696/a-neurocomputational-approach-to-trained-and-transitive-relations-in-equivalence-classes
#14
Ángel E Tovar, Gert Westermann
A stimulus class can be composed of perceptually different but functionally equivalent stimuli. The relations between the stimuli that are grouped in a class can be learned or derived from other stimulus relations. If stimulus A is equivalent to B, and B is equivalent to C, then the equivalence between A and C can be derived without explicit training. In this work we propose, with a neurocomputational model, a basic learning mechanism for the formation of equivalence. We also describe how the relatedness between the members of an equivalence class is developed for both trained and derived stimulus relations...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29092510/switched-ratiometric-lock-in-amplifier-enabling-sub-ppm-measurements-in-a-wide-frequency-range
#15
G Gervasoni, M Carminati, G Ferrari
Lock-in amplifiers (LIAs) are extensively used to perform high-resolution measurements. Ideally, when using LIAs, it would be possible to measure a minimum signal variation limited by the instrument input equivalent noise at the operating frequency and the chosen filtering bandwidth. Instead, digital LIAs show an unforeseen 1/f noise at the instrument demodulated output, proportional to the signal amplitude that poses a fundamental limit to the minimum detectable signal variation using the lock-in technique...
October 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/29058320/the-transfer-of-crel-contextual-control-same-opposite-less-than-more-than-through-equivalence-relations
#16
William F Perez, Roberta Kovac, Yara C Nico, Daniel M Caro, Adriana P Fidalgo, Ila Linares, João Henrique de Almeida, Júlio C de Rose
According to Relational Frame Theory (RFT) Crel denotes a contextual stimulus that controls a particular type of relational response (sameness, opposition, comparative, temporal, hierarchical etc.) in a given situation. Previous studies suggest that contextual functions may be indirectly acquired via transfer of function. The present study investigated the transfer of Crel contextual control through equivalence relations. Experiment 1 evaluated the transfer of Crel contextual functions for relational responses based on sameness and opposition...
October 23, 2017: Journal of the Experimental Analysis of Behavior
https://www.readbyqxmd.com/read/29053832/reward-deficits-in-behavioural-variant-frontotemporal-dementia-include-insensitivity-to-negative-stimuli
#17
David C Perry, Samir Datta, Virginia E Sturm, Kristie A Wood, Jessica Zakrzewski, William W Seeley, Bruce L Miller, Joel H Kramer, Howard J Rosen
During reward processing individuals weigh positive and negative features of a stimulus to determine whether they will pursue or avoid it. Though patients with behavioural variant frontotemporal dementia display changes in their pursuit of rewards, such as food, alcohol, money, and sex, the basis for these shifts is not clearly established. In particular, it is unknown whether patients' behaviour results from excessive focus on rewards, insensitivity to punishment, or to dysfunction in a particular stage of reward processing, such as anticipation, consumption, or action selection...
October 7, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/29041976/human-pupillary-light-reflex-during-successive-irradiation-with-1-ms-blue-and-green-pulsed-light
#18
Soomin Lee, Naoko Muto, Yoshihiro Shimomura, Tetsuo Katsuura
BACKGROUND: In the human retina, the contribution of intrinsically photosensitive retinal ganglion cells (ipRGCs) to the regulation of the pupillary response remains poorly understood. The objective of the current study was to determine the response dynamics of the pupillary light reflex to short, successive pulses of light. In order to better assess the roles of ipRGCs and cones, we used pulses of blue and green light. METHODS: Each participant was exposed to 1-ms blue (466 nm) and/or green (527 nm) light pulses simultaneously or separately, with inter-stimulus intervals (ISIs) of 0, 250, 500, 750, or 1000 ms...
October 17, 2017: Journal of Physiological Anthropology
https://www.readbyqxmd.com/read/29031809/grouping-subjects-based-on-conditioning-criteria-reveals-differences-in-acquisition-rates-and-in-strength-of-conditioning-specific-reflex-modification
#19
Carrie A Smith-Bell, Bernard G Schreurs
Averaging behavioral data such as the nictitating membrane response (NMR) across subjects can conceal important individual and group differences. Analyses were conducted of NMR data from rabbits that were grouped based on the point during NMR conditioning when subjects produced 8 conditioned responses (CR) in a set of 10 trials. This resulted in five groups (Early Day 1, Late Day 1, Early Day 2, Late Day 2, Early Day 3) in which group differences in CR acquisition rates were found. Percent (%) CRs were not found to increase monotonically and between-session differences in % CR were found...
October 13, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28986084/on-the-functional-significance-of-retrieval-mode-task-switching-disrupts-the-recollection-of-conceptual-stimulus-information-from-episodic-memory
#20
Kristina Küper
Episodic memory retrieval is assumed to be associated with the tonic cognitive state of retrieval mode. Despite extensive research into the neurophysiological correlates of retrieval mode, as of yet, relatively little is known about its functional significance. The present event-related potential (ERP) study was aimed at examining the impact of retrieval mode on the specificity of memory content retrieved in the course of familiarity and recollection processes. In two experiments, participants performed a recognition memory inclusion task in which they had to distinguish identically repeated and re-colored versions of study items from new items...
October 3, 2017: Brain Research
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