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blood investigations post op patients

S Samaneh Lashkarinia, Senol Piskin, Tijen A Bozkaya, Ece Salihoglu, Can Yerebakan, Kerem Pekkan
Surgical treatment of congenital heart disease (CHD) involves complex vascular reconstructions utilizing artificial and native surgical materials. A successful surgical reconstruction achieves an optimal hemodynamic profile through the graft in spite of the complex post-operative vessel growth pattern and the altered pressure loading. This paper proposes a new in silico patient-specific pre-surgical planning framework for patch reconstruction and investigates its computational feasibility. The proposed protocol is applied to the patch repair of main pulmonary artery (MPA) stenosis in the Tetralogy of Fallot CHD template...
May 14, 2018: Annals of Biomedical Engineering
B Ö Malekzadeh, M C Erlandsson, P Tengvall, A Palmquist, M Ransjo, M I Bokarewa, A Westerlund
Osteoporosis is a major cause of age-related fractures. Healing complications in osteoporotic patients are often associated with increased mortality and morbidity. Stimulation of the implant-adjacent bone could be beneficial in terms of the surgical outcome. Over the past decade, numerous investigations have implicated insulin in normal bone growth, and recent studies have described the advantages of administering insulin locally to increase bone formation. Therefore, we hypothesized that insulin-coated titanium implants would increase bone formation in osteoporotic animals...
April 19, 2018: Journal of Biomedical Materials Research. Part A
Rafael De la Garza Ramos, C Rory Goodwin, Amit Jain, Daniel Martinez-Ramirez, Isaac O Karikari, Daniel M Sciubba
Background: To investigate the inpatient perioperative morbidity rate of patients with movement disorders (MD) after spinal deformity surgery. Methods: The Nationwide Inpatient Sample database from 2002 to 2011 was queried to identify adult patients with MD who underwent spinal deformity surgery. Complication rates were compared between patients with MD and controls. A multiple logistic regression analysis was conducted to assess the effect of MD on outcome. Results: A total of 365 patients with MD (3...
December 2017: Journal of Spine Surgery (Hong Kong)
Jerry Y Du, Paul D Kiely, Motasem Al Maaieh, Alexander Aichmair, Russel C Huang
BACKGROUND: To assess the clinical outcomes of 20 patients who underwent single level unilateral pedicle screw fixation following lateral lumbar interbody fusion (LLIF) for treatment of lumbar adjacent segment disease (ASD). METHODS: Demographic, comorbidity, clinical assessment, peri-operative, and complication data were assessed. Visual analog scale (VAS), Oswestry disability index (ODI), and short form-12 (SF-12) were used to assess clinical outcomes. Post-operative radiographs were assessed for subsidence, cage migration, and fusion...
September 2017: Journal of Spine Surgery (Hong Kong)
Haiqing Li, Zhize Yuan, Sen Li, Quan Qi, Jun Liu, Mi Zhou, Junfeng Cai, Anqing Chen, Zhe Wang, Xiaofeng Ye, Qiang Zhao
BACKGROUND: Matrix metalloproteinase 9 (MMP9) has recently emerged as a risk predictor in patients with cardiovascular diseases. However, little is known about the significance of increased plasma MMP9 in patients with perioperative myocardial injury. We aimed to investigate the role of MMP9 in the occurrence of myocardial injury during off-pump coronary artery bypass grafting (OPCAB). METHODS: A total of 34 consecutive patients with coronary artery diseases (CAD) were recruited in this prospective, observational study...
April 2017: Journal of Thoracic Disease
Iren Borgen, Lisa Maria Garnweidner-Holme, Anne Flem Jacobsen, Kirsti Bjerkan, Seraj Fayyad, Pål Joranger, Anne Marie Lilleengen, Annhild Mosdøl, Josef Noll, Milada Cvancarova Småstuen, Laura Terragni, Liv Elin Torheim, Mirjam Lukasse
INTRODUCTION: The promotion of a healthy diet, physical activity and measurement of blood glucose levels are essential components in the care for women with gestational diabetes mellitus (GDM). Smartphones offer a new way to promote health behaviour. The main aim is to investigate if the use of the Pregnant+ app, in addition to standard care, results in better blood glucose levels compared with current standard care only, for women with GDM. METHODS AND ANALYSIS: This randomised controlled trial will include 230 pregnant women with GDM followed up at 5 outpatient departments (OPD) in the greater Oslo Region...
March 27, 2017: BMJ Open
Rachel A Moses, Deepak Agarwal, Eric P Raffin, Boyd R Viers, Vidit Sharma, Amy E Krambeck, Vernon M Pais
OBJECTIVE: To investigate the incidence of systemic inflammatory response syndrome (SIRS) following percutaneous nephrolithotomy (PCNL) and evaluate any association with unplanned 90-day readmission. METHODS: We retrospectively reviewed consecutive patients undergoing PCNL in 2 dedicated endourologic practices between 2009 and 2013. We collected patient demographics, perioperative culture data, and operative characteristics. SIRS was defined as having 2 or more of the following: maximum white blood cell count >12,000 or <4000, temperature >38 or <34°C, heart rate >90, and respiratory rate >20 within the first 24 hours following PCNL...
February 2017: Urology
Nannan Guo, Feng Lou, Yongfu Ma, Jie Li, Bo Yang, Wei Chen, Hua Ye, Jing-Bo Zhang, Ming-Yu Zhao, Wen-Jun Wu, Rong Shi, Lindsey Jones, Katherine S Chen, Xue F Huang, Si-Yi Chen, Yang Liu
Circulating tumor DNA (ctDNA) in peripheral blood is a "liquid biopsy" that contains representative tumor information including gene mutations. Additionally, repeated ctDNA samples can be easily obtained to monitor response to treatment and disease progression, which may be especially valuable to lung cancer patients with tumors that cannot be easily biopsied or removed. To investigate the changes in ctDNA after surgical tumor resection, tumor and blood samples obtained before and after surgery were collected prospectively from 41 non-small lung cancer (NSCLC) patients...
September 19, 2016: Scientific Reports
C Tsioufis, K Dimitriadis, A Kasiakogias, T Kalos, I Liatakis, E Koutra, L Nikolopoulou, E Lau, V Papademetriou, D Tousoulis
OBJECTIVE: This study aimed to investigate the effects of renal denervation (RDN) on sympathetic nerve activity and insulin resistance in patients with metabolic syndrome at 3 months post-RDN. DESIGN AND METHOD: Seventeen patients fulfilled 4/5 criteria for metabolic syndrome and under stable use of at least two anti-hypertensive drugs at maximum tolerated doses for at least 4 weeks were enrolled and randomized in 3:1 ratio to RDN [n = 13, 12 males, age: 58 ± 7 years] and Control groups [n = 4, 3 males, age: 60 ± 5 years]...
September 2016: Journal of Hypertension
F Wei, Z Y Zhang, L Thijs, W Y Yang, L Jacobs, N Cauwenberghs, Y M Gu, T Kuznetsova, K Allegaert, P Verhamme, Y Li, H A J Struijker-Boudier, J A Staessen
OBJECTIVE: To investigate to what extent conventional (CBP) and daytime ambulatory (ABP) blood pressure predict narrowing of the retinal microvasculature. DESIGN AND METHOD: In a population-based longitudinal study, 783 white Flemish participants (mean age, 38.2 years; 51.3% women) were randomly recruited, whose blood pressure was measured at baseline and follow-up and who underwent retinal photography at follow-up. CBP and ABP were averaged of five consecutive auscultatory readings and ambulatory oscillometric readings (10 AM-8 PM) programmed at 20 minute intervals...
September 2016: Journal of Hypertension
Abhay Kumar Chaudhary, Girish Kumar Aneja, Shubhra Shukla, Syed Mohd Razi
INTRODUCTION: Left ventricular diastolic dysfunction (LVDD) represents the first stage of diabetic cardiomyopathy preceding changes in systolic function, reinforcing the importance of early examination of ventricular function in individuals with diabetes mellitus (DM). This cross-sectional study was conducted to determine the incidence of asymptomatic LVDD in newly diagnosed normotensive cases of type 2 diabetes subjects, and its relation to glycosylated haemoglobin (HbA1C), age at the time of diagnosis, body mass index (BMI) and serum total cholesterol...
August 2015: Journal of Clinical and Diagnostic Research: JCDR
A Soltani, D Reid, K Wills, E H Walters
BACKGROUND AND AIM: To determine predictors of short- and long-term outcomes in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) (AECOPD) presenting to hospital. METHODS: A prospective clinical audit of AECOPD attendances to the only public acute general hospital in Southern Tasmania, Australia. Out of 416 attendances with AECOPD to the emergency department (ED) between November 2006 and July 2008, 150 patients with 218 attendances were followed to March 2009...
September 2015: Internal Medicine Journal
Craig Allen Kuhns, Cristi R Cook, John R Dodam, Stacey Benton Leach, Keiichi Kuroki, Tyler James Jenkins, Anne Marie Tallmage, Daniel Gerard Hoernschemeyer
STUDY DESIGN: Prospective porcine animal model. OBJECTIVE: Determine if injecting FloSeal into pedicles for hemostasis causes emboli. SUMMARY OF BACKGROUND DATA: Bleeding from spinal deformity cases can be substantial, especially when surgical procedures involve bilateral fixation at multiple segments. It is not unusual to observe hemorrhage from vascular pedicles during each step of pedicle screw tract preparation. When multiple fixation points are required, blood loss can be excessive...
February 15, 2015: Spine
Tom De Beule, Katya Op de Beeck, Gert De Hertogh, Gregory Sergeant, Geert Maleux
A 23-year-old man presented with hypovolemic shock due to a lower gastrointestinal bleeding. Radiological and endoscopic investigation did not reveal the bleeding site. Emergency visceral angiography showed contrast extravasation at a right-sided branch of the superior mesenteric artery (SMA). Embolization of the bleeding point was performed, resulting in bleeding cessation. One week later, the patient presented with a new episode of moderate anal blood loss associated with diffuse abdominal pain. Computed tomography (CT) revealed an ischemic small bowel diverticulum that was treated by a laparoscopically-assisted segmental small bowel resection...
October 2014: Acta Radiologica Short Reports
Vijay Vanam, Priya Debnath, Naga Swetha Bommisetty, Viswanath Vasudevan, Qammar Abbas, Praveen Jinnur, Ameer Rasheed
SESSION TITLE: Quality & Clinical Improvement Posters IISESSION TYPE: Original Investigation PosterPRESENTED ON: Wednesday, October 29, 2014 at 01:30 PM - 02:30 PMPURPOSE: The study was undertaken to ascertain compliance with The Brooklyn Hospital CPAP/NiPPV policy/protocol (adapted from Canadian Medical Association evidence based guideline publication CMAJ 2011, 183(3) & Journalof Respiratory care). Identify opportunities for improvement in safe, effective and cost-efficient utilization of NiPPV/CPAP in acute respiratory failure...
October 1, 2014: Chest
E Iu Maĭchuk, I V Voevodina, T V Mitrokhina, I A Makarova, S V Iureneva
AIM: To study the formation of and trends in risk factors (RFs) for cardiovascular disease (CVD), their influence on the occurrence of early (preclinical) atherosclerotic lesions, a combination of these changes with osteoporosis (OP) in women following bilateral oophorectomy depending on whether hormone replacement therapy (HRT) is performed. SUBJECTS AND METHODS: The investigation enrolled 50 women with surgical menopause after bilateral oophorectomy in combination with hysterectomy who received estrogen monotherapy (a study group) and 37 patients who underwent the same operation, but had no HRT (a control group)...
2014: Terapevticheskiĭ Arkhiv
I Ahmed, S Hashmi, F Tanwir, S Ahmed, M S Khan
BACKGROUND: Tuberculosis is highly prevalent in Pakistan and the numbers are on increase each year. Cervical lymphadenopathy, a common finding in tuberculosis and other inflammatory, infectious and malignant etiologies, is commonly encountered in hospital setting in Karachi, Pakistan. Signs and symptoms of tuberculosis are blood tinged sputum, weight loss, night sweats, loss of appetite and weakness. A through history, complete physical examination and investigations are needed to diagnose tuberculosis...
September 2014: Oral Health and Dental Management
Essam Eldin Mohamed Nour Eldin, Abdullah Almarzouki, Adel Mohamed Assiri, Osman Mohammed Elsheikh, Badreldin Elsonni Abdalla Mohamed, Abdullatif Taha Babakr
BACKGROUND: Oxidative modification of low density lipoproteins (LDL) convert these native particles into pathogenic, immunogenic and atherogenic particles. Factors enhance LDL oxidation are poorly understood, especially in conditions of hyperglycemia. The present study was conducted to investigate which metabolic conditions are associated with the promotion of LDL oxidation in different glycemic situations. METHODS: Adult male participants (274) were selected from patients admitted to the outpatient department of Diabetes Center in Al-Noor Specialized Hospital in Makkah and other citizens and residents in the city...
2014: Diabetology & Metabolic Syndrome
Ricardo Soares, Antonina Di Benedetto, Zach Dovey, Simon Bott, Roy G McGregor, Christopher G Eden
OBJECTIVES: To investigate the long-term outcomes of laparoscopic radical prostatectomy (LRP). PATIENTS AND METHODS: In all, 1138 patients underwent LRP during a 163-month period from 2000 to 2008, of which 51.5%, 30.3% and 18.2% were categorised into D'Amico risk groups of low-, intermediate- and high-risk, respectively. All intermediate- and high-risk patients were staged by preoperative magnetic resonance imaging or computed tomography and isotope bone scanning, and had a pelvic lymph node dissection (PLND), which was extended after April 2008...
April 2015: BJU International
Anandhalakshmi S, Manikandan S, Ganeshkumar P, Ramachandran C
BACKGROUND: The incidence of diabetes is increasing tremendously throughout the world especially in the developing countries. This disease affects various organs like eyes, nerves, kidneys and the heart. In this study, we investigated whether lungs are also one of the target organs of diabetes mellitus or not. AIM: To assess the pulmonary function parameters including alveolar gas exchange in patients with Type 2 Diabetes mellitus and to find the influence of hyperglycaemia and duration of diabetes...
September 2013: Journal of Clinical and Diagnostic Research: JCDR
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