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https://www.readbyqxmd.com/read/29684157/effects-of-white-mulberry-morus-alba-heartwood-extract-against-reticulitermes-flavipes-blattodea-rhinotermitidae
#1
B Hassan, M E Mankowski, G T Kirker, C A Clausen, S Ahmed
Heartwood extract from white mulberry (Morus alba L.) (Rosales: Moraceae) were investigated for antitermitic activity against Reticulitermes flavipes (Kollar) (Blattodea: Rhinotermitidae) in laboratory experiments. An ethanol:toluene (2:1) solvent system was used to remove extract from heartwood shavings. A concentration-dependent feeding response and mortality were observed for termites exposed to a concentration series range of 1.25 to 10 mg/ml of extract based on their dry weight. Results showed that maximum termite mortality occurred at 10 mg/ml...
April 19, 2018: Journal of Economic Entomology
https://www.readbyqxmd.com/read/29684150/prevalence-and-characterization-of-azole-resistant-aspergillus-fumigatus-in-patients-with-cystic-fibrosis-a-prospective-multicentre-study-in-germany
#2
R Seufert, L Sedlacek, B Kahl, M Hogardt, A Hamprecht, G Haase, F Gunzer, A Haas, S Grauling-Halama, C R MacKenzie, A Essig, F Stehling, S Sutharsan, S Dittmer, D Killengray, D Schmidt, N Eskandarian, E Steinmann, J Buer, F Hagen, J F Meis, P-M Rath, J Steinmann
Objectives: Aspergillus fumigatus is the most prevalent filamentous fungus in the respiratory tract of patients with cystic fibrosis (CF). The aim of this prospective multicentre study was to investigate the prevalence of azole-resistant A. fumigatus (ARAF) in respiratory secretions from CF patients across Germany and to characterize ARAF isolates by phenotypic and molecular methods. Methods: Twelve tertiary care centres from Germany participated in the study. In total, 2888 A...
April 19, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29681401/capacity-control-and-responsibility-in-parkinson-s-disease-patients-with-impulse-control-disorders-views-of-neurological-and-psychiatric-experts
#3
Andrew Dawson, Jordie Michael, Ella Dilkes-Frayne, Wayne Hall, Nadeeka N Dissanayaka, Adrian Carter
Dopamine replacement therapy can induce impulse control disorders (ICDs) (e.g., hypersexuality) in susceptible Parkinson's disease patients. ICDs can sometimes result in criminal offending. In a number of past Commonwealth cases, it appears offending ICD patients have been considered to be suffering from 'irresistible impulses' such that their decision-making capacity, behavioural control and responsibility were totally compromised. This contrasts with courts' general scepticism of drug-induced 'compulsion' in cases of addiction-related offending...
April 19, 2018: International Journal of Law and Psychiatry
https://www.readbyqxmd.com/read/29680975/increased-fibulin-1-plasma-levels-in-polycystic-ovary-syndrome-pcos-patients-possible-contribution-to-the-link-between-pcos-and-cardiovascular-risk
#4
E Scarinci, A Tropea, G Russo, G Notaristefano, C Messana, O Alesiani, S M Fabozzi, A Lanzone, R Apa
PURPOSE: To investigate a possible relation between fibulin-1 plasma levels and PCOS. DESIGN: ELISA quantitative determination of human fibulin-1. METHODS: 50 women with PCOS and 40 control patients who attended the Unit of Human Reproductive Pathophysiology, Università Cattolica del Sacro Cuore, Rome, were enrolled. Ultrasonographic pelvic examinations, hormonal profile assays, oral tolerance test OGTT, lipid profile and ELISA quantitative determination of human fibulin-1 were performed...
April 21, 2018: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29680397/effect-of-kibble-and-raw-meat-diets-on-peripheral-blood-mononuclear-cell-gene-expression-profile-in-dogs
#5
R C Anderson, K M Armstrong, W Young, P Maclean, D G Thomas, E N Bermingham
Peripheral blood mononuclear cell (PBMC) gene expression microarray profiling is a minimally invasive tool used in human diet intervention studies. In this study, PBMC gene expression was determined in dogs fed kibble or raw red meat diets for 9 weeks to test the hypothesis that diet influences canine immune cell gene expression profiles. The two diets were associated with differences in PBMC gene expression profiles, which corresponded with changes in plasma IgA concentrations. Analysis of PBMC gene expression profiles might provide useful insights into the long term effects of diet on health outcomes in dogs...
April 2018: Veterinary Journal
https://www.readbyqxmd.com/read/29680290/estrogen-receptor-beta-signaling-inhibits-pdgf-induced-human-airway-smooth-muscle-proliferation
#6
Nilesh Sudhakar Ambhore, Rathnavali Katragadda, Rama Satyanarayana Raju Kalidhindi, Michael A Thompson, Christina M Pabelick, Y S Prakash, Sathish Venkatachalem
Airway smooth muscle (ASM) cell hyperplasia driven by persistent inflammation is a hallmark feature of remodeling in asthma. Sex steroid signaling in the lungs is of considerable interest, given epidemiological data showing more asthma in pre-menopausal women and aging men. Our previous studies demonstrated that estrogen receptor (ER) expression increases in asthmatic human ASM; however, very limited data are available regarding differential roles of ERα vs. ERβ isoforms in human ASM cell proliferation. In this study, we evaluated the effect of selective ERα and ERβ modulators on platelet-derived growth factor (PDGF)-stimulated ASM proliferation and the mechanisms involved...
April 19, 2018: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/29680062/use-of-biopolymeric-coating-hydrophobized-with-beeswax-in-post-harvest-conservation-of-guavas
#7
V R L Oliveira, F K G Santos, R H L Leite, E M M Aroucha, K N O Silva
Biopolymeric coatings are effective in maintaining the chemical and sensory characteristics of fruits and vegetables because they preserve innumerable nutrients effectively for long periods of storage. Coatings based on cornstarch (3%), cassava starch (2%) and gelatin (5%) were synthesized. Beeswax (BW) was added as a hydrophobic agent in the polymeric network at different concentrations relative to the dry base of biopolymer. The biofilm containing 10% BW presented the best results in the water vapor transmission rate (WVTR) and the effect of the BW incorporation was also evaluated from surface roughness and SEM...
September 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29679940/nmr-based-metabolic-toxicity-of-low-level-hg-exposure-to-earthworms
#8
Ronggui Tang, Changfeng Ding, Fei Dang, Yibing Ma, Junsong Wang, Taolin Zhang, Xingxiang Wang
Mercury is a globally distributed toxicant to aquatic animals and mammals. However, the potential risks of environmental relevant mercury in terrestrial systems remain largely unclear. The metabolic profiles of the earthworm Eisenia fetida after exposure to soil contaminated with mercury at 0.77 ± 0.09 mg/kg for 2 weeks were investigated using a two-dimensional nuclear magnetic resonance-based (1 H-13 C NMR) metabolomics approach. The results revealed that traditional endpoints (e.g., mortality and weight loss) did not differ significantly after exposure...
April 18, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29679833/the-contribution-of-cattle-urine-and-dung-to-nitrous-oxide-emissions-quantification-of-country-specific-emission-factors-and-implications-for-national-inventories
#9
D R Chadwick, L M Cardenas, M S Dhanoa, N Donovan, T Misselbrook, J R Williams, R E Thorman, K L McGeough, C J Watson, M Bell, S G Anthony, R M Rees
Urine patches and dung pats from grazing livestock create hotspots for production and emission of the greenhouse gas, nitrous oxide (N2 O), and represent a large proportion of total N2 O emissions in many national agricultural greenhouse gas inventories. As such, there is much interest in developing country specific N2 O emission factors (EFs) for excretal nitrogen (EF3, pasture, range and paddock) deposited during gazing. The aims of this study were to generate separate N2 O emissions data for cattle derived urine and dung, to provide an evidence base for the generation of a country specific EF for the UK from this nitrogen source...
April 18, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29679775/influence-of-side-effects-on-early-therapy-persistence-with-letrozole-in-post-menopausal-patients-with-early-breast-cancer-results-of-the-prospective-evaluate-tm-study
#10
N Nabieva, T Fehm, L Häberle, J de Waal, M Rezai, B Baier, G Baake, H-C Kolberg, M Guggenberger, M Warm, N Harbeck, R Wuerstlein, J-U Deuker, P Dall, B Richter, G Wachsmann, C Brucker, J W Siebers, M Popovic, T Kuhn, C Wolf, H-W Vollert, G-P Breitbach, W Janni, R Landthaler, A Kohls, D Rezek, T Noesselt, G Fischer, S Henschen, T Praetz, V Heyl, T Kühn, T Krauss, C Thomssen, A Hohn, H Tesch, C Mundhenke, A Hein, C C Hack, K Schmidt, E Belleville, S Y Brucker, S Kümmel, M W Beckmann, D Wallwiener, P Hadji, P A Fasching
BACKGROUND: Endocrine treatment (ET) with an aromatase inhibitor (AI) is the treatment of choice in post-menopausal patients with hormone receptor-positive early breast cancer (EBC). However, adverse events (AEs) often lead to treatment discontinuation. This analysis aimed to identify side-effects that lead to patients failing to persist with letrozole treatment. PATIENTS AND METHODS: Post-menopausal hormone receptor-positive EBC patients starting ET with letrozole were enroled in EvAluate-TM, a non-interventional study...
April 18, 2018: European Journal of Cancer
https://www.readbyqxmd.com/read/29679302/association-of-abnormal-serum-potassium-levels-with-arrhythmias-and-cardiovascular-mortality-a-systematic-review-and-meta-analysis-of-observational-studies
#11
REVIEW
Liesa K Hoppe, Dana C Muhlack, Wolfgang Koenig, Prudence R Carr, Hermann Brenner, Ben Schöttker
PURPOSE: To provide the first systematic review and meta-analysis of observational studies on the association of abnormal serum potassium and cardiovascular outcomes. METHODS: Medline and ISI Web of Knowledge were systematically searched from inception until November 24, 2017. Data synthesis of relevant studies was performed using random effects model meta-analyses. RESULTS: Meta-analyses included 310,825 participants from 24 studies. In the older general population, low serum potassium was associated with a 1...
April 20, 2018: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/29678987/protocol-for-a-phase-iii-non-inferiority-randomised-comparison-of-a-new-fibrinogen-concentrate-versus-cryoprecipitate-for-treating-acquired-hypofibrinogenaemia-in-bleeding-cardiac-surgical-patients-the-fibres-trial
#12
Keyvan Karkouti, Jeannie Callum, Vivek Rao, Nancy Heddle, Michael E Farkouh, Mark A Crowther, Damon C Scales
INTRODUCTION: Coagulopathic bleeding is a serious complication of cardiac surgery to which an important contributor is acquired hypofibrinogenaemia (plasma fibrinogen <1.5-2.0 g/L). The standard intervention for acquired hypofibrinogenaemia is cryoprecipitate, but purified fibrinogen concentrates are also available. There is little comparative data between the two therapies and randomised trials are needed. METHODS AND ANALYSIS: FIBrinogen REplenishment in Surgery (FIBRES) is a multicentre, randomised (1:1), active-control, single-blinded, phase III trial in adult cardiac surgical patients experiencing clinically significant bleeding related to acquired hypofibrinogenaemia...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29678813/prognostic-significance-of-nuisance-bleeding-in-anticoagulated-patients-with-atrial-fibrillation
#13
Emily C O'Brien, DaJuanicia N Holmes, Laine E Thomas, Gregg C Fonarow, Larry A Allen, Bernard J Gersh, Peter R Kowey, Daniel E Singer, Michael D Ezekowitz, Gerald V Naccarelli, Jack E Ansell, Paul S Chan, Kenneth W Mahaffey, Alan S Go, James V Freeman, James A Reiffel, Eric D Peterson, Jonathan P Piccini, Elaine M Hylek
Background -Bleeding is commonly cited as a reason for stopping oral anticoagulants (OAC). Whether minor bleeding events ("nuisance bleeding", NB) in patients with atrial fibrillation (AF) on OAC are associated with OAC discontinuation, major bleeding and stroke/systemic embolism (SSE), is unknown. Methods -Within the ORBIT-AF prospective, outpatient registry, we identified 6771 patients ≥18 years of age at 172 sites with AF and eligible followup visits. NB was ascertained from the medical record and was defined as minor bleeding that did not require medical attention (e...
April 20, 2018: Circulation
https://www.readbyqxmd.com/read/29678770/self-reported-pain-in-patients-with-schizophrenia-results-from-the-national-first-step-face-sz-cohort
#14
Guillaume Fond, Laurent Boyer, Meja Andrianarisoa, Ophelia Godin, Ewa Bulzacka, Fabrice Berna, Lore Brunel, Nathalie Coulon, Bruno Aouizerate, Delphine Capdevielle, Isabelle Chereau, Thierry D'amato, Hélène Denizot, Caroline Dubertret, Julien Dubreucq, Catherine Faget, Sylvain Leignier, Jasmina Mallet, David Misdrahi, Romain Rey, Christophe Lancon, Christine Passerieux, Aurélie Schandrin, Mathieu Urbach, Pierre Vidailhet, Marion Leboyer, Franck Schurhoff, Pierre-Michel Llorca, M Andrianarisoa, B Aouizerate, F Berna, O Blanc, L Brunel, E Bulzacka, D Capdevielle, I Chereau-Boudet, G Chesnoy-Servanin, Danion Jm, T D'Amato, A Deloge, C Delorme, H Denizot, J M Dorey, C Dubertret, J Dubreucq, C Faget, C Fluttaz, G Fond, S Fonteneau, F Gabayet, E Giraud-Baro, R M Honciuc, D Lacelle, C Lançon, H Laouamri, M Leboyer, T Le Gloahec, Y Le Strat, Llorca, J Mallet, E Metairie, D Misdrahi, I Offerlin-Meyer, C Passerieux, P Peri, S Pires, C Portalier, R Rey, C Roman, M Sebilleau, A Schandrin, F Schurhoff, A Tessier, Tronche Am, M Urbach, F Vaillant, A Vehier, P Vidailhet, E Vilà, H Yazbek, A Zinetti-Bertschy
INTRODUCTION: Little is known about perception of physical pain in schizophrenia (SZ). Some studies have suggested that patients with SZ may have an increased pain threshold, while others have suggested that patients with SZ may suffer from undetected and untreated high physical pain levels. The objectives of this study were (i) to investigate the prevalence of self-reported physical pain in stabilized SZ subjects, and (ii) to determine whether physical pain was associated with psychiatric characteristics and somatic comorbidities (iii) to determine whether antidepressants and benzodiazepine administration were associated with lower self-reported pain...
April 17, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29678160/the-increasing-burden-and-complexity-of-multi-morbidity-and-polypharmacy-in-geriatric-hiv-patients-a-cross-sectional-study-of-people-aged-65-74-years-and-more-than-75-years
#15
G Guaraldi, A Malagoli, A Calcagno, C Mussi, B M Celesia, F Carli, S Piconi, G V De Socio, A M Cattelan, G Orofino, A Riva, E Focà, S Nozza, G Di Perri
BACKGROUND: Geriatric Patients Living with HIV/AIDS (GEPPO) is a new prospective observational multicentre cohort consisting of all the HIV-positive geriatric patients being treated at 10 clinics in Italy, and HIV-negative controls attending a single geriatric clinic. The aim of this analysis of the GEPPO cohort was to compare prevalence and risk factors of individual non-communicable diseases (NCD), multi-morbidity (MM) and polypharmacy (PP) amongst HIV positive and HIV negative controls at enrolment into the GEPPO cohort...
April 20, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29676982/bond-stability-of-a-universal-adhesive-system-to-eroded-abraded-dentin-after-deproteinization
#16
M G Augusto, Crg Torres, C R Pucci, N Schlueter, A B Borges
OBJECTIVE: Erosive/abrasive challenges can potentially compromise bonding to dentin. Aiming to improve the quality and stability of bonding to this substrate, this study investigated the combined effect of erosion and toothbrush abrasion on the microtensile bond strength (μTBS) stability to dentin using a universal adhesive system in total and self-etching modes, associated or not associated with deproteinization. METHODS: Bovine dentin specimens were divided into five groups according to the organic matrix condition (n=20): control (C); erosion (E); erosion + abrasion (EA); erosion + sodium hypochlorite (EH); erosion + abrasion + sodium hypochlorite (EAH)...
May 2018: Operative Dentistry
https://www.readbyqxmd.com/read/29676932/exoplanet-biosignatures-a-framework-for-their-assessment
#17
David C Catling, Joshua Krissansen-Totton, Nancy Y Kiang, David Crisp, Tyler D Robinson, Shiladitya DasSarma, Andrew J Rushby, Anthony Del Genio, William Bains, Shawn Domagal-Goldman
Finding life on exoplanets from telescopic observations is an ultimate goal of exoplanet science. Life produces gases and other substances, such as pigments, which can have distinct spectral or photometric signatures. Whether or not life is found with future data must be expressed with probabilities, requiring a framework of biosignature assessment. We present a framework in which we advocate using biogeochemical "Exo-Earth System" models to simulate potential biosignatures in spectra or photometry...
April 20, 2018: Astrobiology
https://www.readbyqxmd.com/read/29676800/validation-of-an-in-vitro-sun-protection-factor-spf-method-in-blinded-ring-testing
#18
M Pissavini, C Tricaud, G Wiener, A Lauer, M Contier, L Kolbe, C Trullás Cabanas, F Boyer, V Nollent, E Meredith, E Dietrich, P J Matts
OBJECTIVE: The objective of this work was to investigate the utility of a new in vitro SPF test method in blinded ring-testing, against new ISO acceptance criteria. METHODS: 24 blinded, commercial, emulsion-type, primary sunscreen products, covering the full range of labelled SPF in Europe (SPF6 - 50+), were tested by 3 test institutes using the current ISO24444:2010 In Vivo SPF Test Method and simultaneously by 3 separate test laboratories using a new candidate in vitro SPF test method, developed under the leadership of Cosmetics Europe (CE)...
April 20, 2018: International Journal of Cosmetic Science
https://www.readbyqxmd.com/read/29676772/functional-roles-of-eriocalyxin-b-in-zebrafish-revealed-by-transcriptome-analysis
#19
Xunian Zhou, Cyanne Ye Cao, Angel Tsz-Yau Wan, Grace Gar-Lee Yue, Frankie Hin-Fai Kwok, Kwok-Pui Fung, Handong Sun, Clara Bik-San Lau, Pema-Tenzin Puno, Stephen Kwok-Wing Tsui
BACKGROUND: Eriocalyxin B (EriB) is a natural ent-kaurane diterpenoid obtained from Isodon eriocalyx var. laxiflora (family Lamiaceae), which has multiple biological activities (e.g. anti-tumor and anti-inflammatory) via the alteration of gene expression and signaling transduction. Recently, RNA sequencing (RNA-seq) has been developed as a dynamic transcriptome approach to analyze the transcriptional profile and in addition use such gene expression profiles to identify novel candidate genes in a zebrafish model...
April 20, 2018: Molecular omics
https://www.readbyqxmd.com/read/29676723/paraburkholderia-caseinilytica-sp-nov-isolated-from-the-pine-and-broad-leaf-mixed-forest-soil
#20
Zeng-Hong Gao, Shu-Fen Zhong, Zu-Er Lu, Sen-Yang Xiao, Li-Hong Qiu
A novel Gram-stain-negative, aerobic, non-spore-forming, motile and rod-shaped bacterial strain, designated HM451T , was isolated from forest soil sampled at the Dinghushan Biosphere Reserve, Guangdong Province, PR China (112° 31' E 23° 10' N). It grew optimally at 28 °C, pH 5.0-6.0 and in the presence of 0-2.5 % (w/v) NaCl on R2A medium. Strain HM451T was closely related to Paraburkholderia mimosarum NBRC 106338T (98.6 % 16S rRNA gene sequence similarity), Paraburkholderia heleia NBRC 101817T (98...
April 20, 2018: International Journal of Systematic and Evolutionary Microbiology
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