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Global longitudinal strain

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https://www.readbyqxmd.com/read/28728485/factors-associated-with-global-longitudinal-strain-decline-in-hypertensive-patients-with-normal-left-ventricular-ejection-fraction
#1
Nabila Soufi Taleb Bendiab, Abderrahim Meziane-Tani, Souhila Ouabdesselam, Nadera Methia, Samia Latreche, Latefa Henaoui, Jean-Jacques Monsuez, Salim Benkhedda
Background Early detection of risk factors for left ventricular (LV) dysfunction may be useful in patients with high blood pressure (HBP). Methods Patient from an outpatient HBP clinic underwent a two-dimensional Doppler-coupled echocardiography with determination of LV global longitudinal strain (GLS) by speckle-tracking. Results Among 200 patients (mean age 61.7 ± 9.7 years), 155 were overweight, 93 had diabetes, 83 had dyslipidemia, and 109 had uncontrolled HBP. LV hypertrophy (LVH) was found in 136 patients (68%), including concentric ( n = 106) and eccentric ( n = 30) LVH...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28716430/non-invasive-evaluation-of-right-ventricular-function-with-real-time-3-d-echocardiography
#2
Ran Chen, Meihua Zhu, Kacie Amacher, Xia Wu, David J Sahn, Muhammad Ashraf
The aim of this study was to evaluate the accuracy and feasibility of real-time 3-D echocardiography (3-DE) in assessing right ventricular (RV) systolic function. A latex balloon was inserted into the right ventricle of 20 freshly harvested pig hearts which were then passively driven by a pulsatile pump apparatus. The RV global longitudinal strain (GLS), global circumferential strain (GCS), global area strain (GAS) and RV ejection fraction (RVEF), derived from 3-DE, as well as the RVEF obtained from 2-D echocardiography (2-DE) were quantified at different stroke volumes (30-70 mL) and compared with sonomicrometry data...
July 14, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28715068/severe-mitral-regurgitation-is-associated-with-increased-copeptin-levels-in-heart-failure-with-reduced-ejection-fraction
#3
Alven Kılıcgedık, Elıf Eroglu, Gokhan Kahvecı, Khaganı Isgandarov, Emrah Acar, Semi Ozturk, Regayip Zehir, Seyhmus Kulahcıoglu, Cuneyt Toprak, Ali Yaman, Ibrahım Akın Izgı, Cevat Kirma
BACKGROUND AND AIM: The objective of this study was to assess the potential role of mitral regurgitation (MR) in the release of copeptin in HF patients with reduced ejection fraction (HFREF). METHODS: The study included 63 patients of whom 33 had functional mild MR (Group 1) and 30 had functional severe MR (Group 2).The functional classes of the groups were both NYHA Class III. Blood samples for the determination of plasma copeptin and B-type natriuretic peptide (BNP) levels were obtained at the same day with the echocardiographic examination...
July 17, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28714947/long-term-systolic-function-in-children-and-young-adults-after-hematopoietic-stem-cell-transplant
#4
S J Rotz, C E Dandoy, M D Taylor, S Jodele, J L Jefferies, A Lane, J A El-Bietar, A W Powell, S M Davies, T D Ryan
Congestive heart failure and subclinical left ventricular systolic dysfunction (LVSD) affect long-term survivors of hematopoietic stem cell transplant (HSCT). Echocardiographic measurements of global longitudinal and circumferential strain have shown promise in identifying subclinical LVSD in cancer survivors. We analyzed echocardiograms in 95 children and young adults with malignancies or bone marrow failure syndromes performed before HSCT and 1-6 years after HSCT. We additionally measured the biomarkers soluble suppression of tumorigenicity-2 (sST-2) and cardiac troponin-I (cTn-I) in the same children through 49 days post HSCT...
July 17, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28710271/novel-alphacoronaviruses-and-paramyxoviruses-co-circulate-with-type-1-and-sars-related-betacoronaviruses-in-synanthropic-bats-in-luxembourg
#5
Maude Pauly, Jacques B Pir, Catherine Loesch, Aurélie Sausy, Chantal J Snoeck, Judith M Hübschen, Claude P Muller
Several infectious disease outbreaks with high mortality in humans have been attributed to viruses that are thought to have evolved from bat viruses. In this study from Luxembourg, the genetic diversity and epidemiology of paramyxoviruses and coronaviruses shed by the bat species Rhinolophus ferrumequinum and Myotis emarginatus was evaluated. Faeces collection (n= 624) was performed longitudinally in a mixed-species colony in 2015 and 2016. In addition, faeces (n= 254) were collected cross-sectionally from six Myotis emarginatus colonies in 2016...
July 14, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28701527/relationship-between-myocardial-function-body-mass-index-and-outcome-after-st-segment-elevation-myocardial-infarction
#6
Emer Joyce, Georgette E Hoogslag, Vasileios Kamperidis, Philippe Debonnaire, Spyridon Katsanos, Bart Mertens, Nina Ajmone Marsan, Jeroen J Bax, Victoria Delgado
BACKGROUND: Better survival for overweight and obese patients after ST-segment-elevation myocardial infarction (STEMI) has been demonstrated. The association between body mass index (BMI), outcome, and left ventricular (LV) structure and function after STEMI, including LV longitudinal strain (global longitudinal strain), was evaluated. METHODS AND RESULTS: First patients with STEMI undergoing primary percutaneous coronary intervention (n=1604; mean age, 61±12 years; 75% men) had BMI measured on admission, and 2-dimensional transthoracic echocardiography performed within 48 hours...
July 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28698259/reversibility-of-cardiac-function-predicts-outcome-after-transcatheter-aortic-valve-replacement-in-patients-with-severe-aortic-stenosis
#7
Kimi Sato, Arnav Kumar, Brandon M Jones, Stephanie L Mick, Amar Krishnaswamy, Richard A Grimm, Milind Y Desai, Brian P Griffin, L Leonardo Rodriguez, Samir R Kapadia, Nancy A Obuchowski, Zoran B Popović
BACKGROUND: Reversibility of left ventricular (LV) dysfunction in high-risk aortic stenosis patient and its impact on survival after transcatheter aortic valve replacement (TAVR) are unclear. We aimed to evaluate longitudinal changes of LV structure and function after TAVR and their impact on survival. METHODS AND RESULTS: We studied 209 patients with aortic stenosis who underwent TAVR from May 2006 to December 2012. Echocardiograms were used to calculate LV end-diastolic volume index (LVEDVi), LV ejection fraction, LV mass index (LVMi), and global longitudinal strain before, immediately (<10 days), late (1-3 months), and yearly after TAVR...
July 11, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28691201/combined-myocardial-deformation-to-predict-cardiac-resynchronization-therapy-response-in-non-ischemic-cardiomyopathy
#8
Ning Yang, Zhao-Guang Liang, Zhao-Jun Wang, Hui Liu, Chao Chi, Yan-Feng Tian, Shu-Han Qi, Bi-Yu Wang, Wei Han
BACKGROUND: 20-30% of patients do not benefit from CRT when the established selection criteria were applied. We hypothesized that a combined assessment of mechanical dyssynchrony, myocardial deformation and diastolic function would identify patients who would benefit most from CRT. METHOD: In 36 CRT patients, clinical evaluation and echocardiography were performed before and after CRT. Patients were classified into 3 subgroups according to their amount of response: echocardiographic responders, clinical responders, and nonresponders...
July 10, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28689753/comparison-of-left-ventricular-function-and-myocardial-infarct-size-determined-by-2-dimensional-speckle-tracking-echocardiography-in-patients-with-and-without-chronic-obstructive-pulmonary-disease-after-st-segment-elevation-myocardial-infarction
#9
Laurien Goedemans, Rachid Abou, Georgette E Hoogslag, Nina Ajmone Marsan, Christian Taube, Victoria Delgado, Jeroen J Bax
Patients with chronic obstructive pulmonary disease (COPD) have a high risk of mortality after acute ST-segment elevation myocardial infarction (STEMI). We compared STEMI patients with versus without COPD in terms of infarct size and left ventricular (LV) systolic function using advanced 2-dimensional speckle tracking echocardiography. Of 1,750 patients with STEMI (mean age 61 ± 12 years, 76% male), 133 (7.6%) had COPD. With transthoracic echocardiography, left ventricular ejection fraction (LVEF) and wall motion score index were measured...
June 15, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28688952/left-ventricular-mechanics-in-children-with-hypertrophic-cardiomyopathy-cmr-study
#10
Łukasz Mazurkiewicz, Lidia Ziółkowska, Joanna Petryka, Mateusz Śpiewak, Łukasz Małek, Agata Kubik, Magdalena Marczak, Jolanta Misko, Grażyna Brzezińska-Rajszys
OBJECTIVES: To assess the magnitude of myocardial displacement abnormalities and their alterations with the fibrosis, left-ventricular (LV) outflow tract obstruction (LVOTO) and hypertrophy in juveniles with hypertrophic cardiomyopathy (HCM). STUDY DESIGN: Fifty-five children [age 12,5±4.6years, 38 (69,1%) males, 19 (34,5%) with LVOTO] with HCM and 20 controls underwent cardiovascular magnetic resonance. The LV feature tracking (FT) derived strain and strain rates were quantified...
July 5, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28687124/role-of-global-longitudinal-strain-in-predicting-outcomes-in-hypertrophic-cardiomyopathy
#11
Hongyun Liu, Iraklis Pozios, Bereketeab Haileselassie, Alexandra Nowbar, Lars L Sorensen, Susan Phillip, Dai-Yin Lu, Ioannis Ventoulis, Hongchang Luo, M Roselle Abraham, Theodore P Abraham
Global longitudinal strain (GLS) is a sensitive indicator of global left ventricular function particularly in those with normal ejection fraction. We examined the potential value of GLS in predicting outcomes in hypertrophic cardiomyopathy (HC). Conventional and strain echocardiography was performed in 400 patients with HC followed for a median 3.1 years (interquartile range 1.2 to 5.6). Peak systolic strain from 3 apical views was averaged to calculate GLS. Patients were divided based on a previously published cutoff value of -16%...
May 30, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28685602/relationship-of-biomarkers-of-extracellular-matrix-with-myocardial-function-in-type-2-diabetes-mellitus
#12
Ju-Hua Liu, Yan Chen, Zhe Zhen, Lai-Ming Ho, Anita Tsang, Michele Yuen, Karen Lam, Hung-Fat Tse, Kai-Hang Yiu
AIM: The study evaluated the relationship of extracellular matrix and renin angiotensin system with myocardial dysfunction in Type 2 diabetes mellitus. METHODS: All patients underwent resting and exercise echocardiography, including conventional parameters, E/E' ratio, global longitudinal strain and diastolic function reserve index. Plasma matrix metalloproteinase-1, TIMP-1, amino-terminal propeptide of type I and type III procollagen and renin angiotensin system activity were measured...
July 7, 2017: Biomarkers in Medicine
https://www.readbyqxmd.com/read/28684639/comparative-effects-of-glucose-and-water-drinks-on-blood-pressure-and-cardiac-function-in-older-subjects-with-and-without-postprandial-hypotension
#13
Laurence G Trahair, Sharmalar Rajendran, Renuka Visvanathan, Matthew Chapman, Daniel Stadler, Michael Horowitz, Karen L Jones
Postprandial hypotension (PPH) occurs frequently and is thought to reflect an inadequate increase in cardiac output to compensate for the rise in splanchnic blood flow after a meal. Gastric distension by water attenuates the postprandial fall in blood pressure (BP). Cardiac hemodynamics (stroke volume (SV), cardiac output (CO), and global longitudinal strain (GLS)) have hitherto not been measured in PPH We sought to determine the comparative effects of water and glucose drinks on cardiac hemodynamics in healthy older subjects and individuals with PPH Eight healthy older subjects (age 71...
July 2017: Physiological Reports
https://www.readbyqxmd.com/read/28679523/global-longitudinal-strain-and-left-atrial-volume-index-provide-incremental-prognostic-value-in-patients-with-hypertrophic-cardiomyopathy
#14
Yasmine L Hiemstra, Philippe Debonnaire, Marianne Bootsma, Erik W van Zwet, Victoria Delgado, Martin J Schalij, Douwe E Atsma, Jeroen J Bax, Nina Ajmone Marsan
BACKGROUND: Current methods for predicting adverse events in patients with hypertrophic cardiomyopathy are still limited. Left ventricular global longitudinal strain (GLS) and left atrial volume index (LAVI) have been recently proposed as novel prognostic factors in several cardiovascular diseases. The objective of this study was to evaluate the prognostic value of GLS and LAVI in patients with hypertrophic cardiomyopathy. METHODS AND RESULTS: Two-dimensional echocardiography was performed in 427 patients with hypertrophic cardiomyopathy (66% men, age 52±15 years), and LAVI and GLS were assessed...
July 2017: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28678927/global-longitudinal-strain-or-left-ventricular-twist-and-torsion-which-correlates-best-with-ejection-fraction
#15
Marcio Silva Miguel Lima, Hector R Villarraga, Maria Cristina Donadio Abduch, Marta Fernandes Lima, Cecilia Beatriz Bittencourt Viana Cruz, João Cesar Nunes Sbano, Mariana Callil Voos, Wilson Mathias, Jeane Mike Tsutsui
Background: Estimative of left ventricular ejection fraction (LVEF) is a major indication for echocardiography. Speckle tracking echocardiography (STE) allows analysis of LV contraction mechanics which includes global longitudinal strain (GLS) and twist/torsion, both the most widely used. Direct comparison of correlations between these novel parameters and LVEF has never been done before. Objective: This study aims to check which one has the highest correlation with LVEF...
June 29, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28674623/the-systolic-paradox-in-hypertrophic-cardiomyopathy
#16
Trine F Haland, Nina E Hasselberg, Vibeke Marie Almaas, Lars A Dejgaard, Jørg Saberniak, Ida S Leren, Knut Erik Berge, Kristina H Haugaa, Thor Edvardsen
OBJECTIVE: We explored cardiac volumes and the effects on systolic function in hypertrophic cardiomyopathy (HCM) patients with left ventricular hypertrophy (HCM LVH+) and genotype-positive patients without left ventricular hypertrophy (HCM LVH-). METHODS: We included 180 HCM LVH+, 100 HCM LVH- patients and 80 healthy individuals. End-Diastolic Volume Index (EDVI), End-Systolic Volume Index (ESVI) and ejection fraction (EF) were assessed by echocardiography. Left ventricular (LV) global longitudinal strain (GLS) was measured by speckle tracking echocardiography...
2017: Open Heart
https://www.readbyqxmd.com/read/28673476/prediction-for-improvement-and-remodeling-in-first-onset-myocardial-infarction-by-speckle-tracking-echocardiography-is-global-or-regional-selection-better
#17
Bo Hu, Qing Zhou, Jinling Chen, Tuantuan Tan, Xue Yao, Hongning Song, Ruiqiang Guo
Cardiac function improvement and chamber remodeling after the onset of acute myocardial infarction (AMI) is crucial as it is closely related to the outcomes of patients. We sought to investigate the predictive value of left ventricular (LV) global and region of interest (ROI) assessment for prognosis of AMI patients by speckle tracking echocardiography (STE). We prospectively enrolled 81 first-onset AMI patients for baseline and 6-mo follow-up analysis. The echocardiography-derived parameters were compared in receiver operator characteristics (ROC) analysis for prediction of LV remodeling (LVR) (a minimum 20% increase of LV end-diastolic volume) and cardiac function improvement (a minimum 5% increase of LV ejection fraction)...
June 30, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28670832/association-between-left-ventricular-perfusion-defects-and-myocardial-deformation-indexes-in-heart-transplantation-recipients
#18
Antonello D'Andrea, Maria Luisa De Rimini, Raffaella America, Chiara Cirillo, Lucia Riegler, Giuseppe Limongelli, Michele D'Alto, Gemma Salerno, Ciro Maiello, Pietro Muto, Maria Giovanna Russo, Raffaele Calabrò, Eduardo Bossone, Giuseppe Pacileo
The aim of the study was to analyze possible correlations between strain echocardiography (STE) and PET myocardial perfusion in a population of heart transplantation (HTx) recipients showing preserved left ventricular (LV) ejection fraction. By STE, LV global longitudinal strain (LV GLS) was lower in HTx. PET showed no transient or chronic ischemia in 83 of 115 HTx (73%). Fixed perfusion defects were observed in 17% of HTx and reversible ischemia in 10%. Significant coronary stenosis was observed only in 10 cases...
July 3, 2017: Echocardiography
https://www.readbyqxmd.com/read/28664480/usefulness-of-left-ventricular-speckle-tracking-echocardiography-and-novel-measures-of-left-atrial-structure-and-function-in-diagnosing-paroxysmal-atrial-fibrillation-in-ischemic-stroke-and-transient-ischemic-attack-patients
#19
Kristoffer Grundtvig Skaarup, Hanne Christensen, Nis Høst, Masti Mahdy Mahmoud, Christian Ovesen, Flemming Javier Olsen, Jan Skov Jensen, Tor Biering-Sørensen
Asymptomatic paroxysmal atrial fibrillation (PAF) is often assumed to be the cause of cryptogenic ischemic strokes (IS) and transient ischemic attacks (TIA). We examined the usefulness of measures obtained by 2D speckle tracking echocardiography and novel left atrial measurements, in the diagnosis of PAF in patients with IS and TIA. We retrospectively included 205 patients who after acute IS or TIA underwent an echocardiogram in sinus rhythm. Patients were designated as PAF-patients if they had one or more reported incidents of AF before or after their echocardiographic examination...
June 29, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28664478/the-integrated-value-of-sst2-and-global-longitudinal-strain-in-the-early-stratification-of-patients-with-severe-aortic-valve-stenosis-a-translational-imaging-approach
#20
Iacopo Fabiani, Lorenzo Conte, Nicola Riccardo Pugliese, Enrico Calogero, Valentina Barletta, Rossella Di Stefano, Tatiana Santoni, Cristian Scatena, Uberto Bortolotti, Antonio Giuseppe Naccarato, Anna Sonia Petronio, Vitantonio Di Bello
Aortic valve stenosis (AVS) is associated with significant myocardial fibrosis (MF). Global longitudinal strain (GLS) is a sensible indicator of systolic dysfunction. ST2 is a member of the interleukin (IL)-1 receptor family and a modulator of hypertrophic and fibrotic responses. We aimed at assessing: (a) the association between adverse LV remodeling, LV functional parameters (including GLS) and sST2 level. (b) The association between MF (detected by endo-myocardial biopsy) and sST2 in patients with AVS undergoing surgical valve replacement...
June 29, 2017: International Journal of Cardiovascular Imaging
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