keyword
MENU ▼
Read by QxMD icon Read
search

Degenerative Disk Disease

keyword
https://www.readbyqxmd.com/read/29772868/-significance-of-cell-autophagy-in-resorption-of-lumbar-disc-herniation
#1
REVIEW
Zhi-Jun Diao, Hong Jiang, Jin-Tao Liu
As a self-protective mechanism of cells, autophagy of cells can maintain cell stability by degrading self-aging substances, and it can be highly induced. The ability of autophagy to degraded cells will decrease with age. The resorption phenomenon after lumbar disc herniation is one of the effective mechanisms in conservative treatment of lumbar disc herniation. The degenerative lesion of intervertebral disc is one of the main reasons of lumbar disc herniation. Cell autophagy is extensive participation in the degeneration of lumbar intervertebral disc, delaying the occurrence of degenerative disease...
April 25, 2018: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29702308/unilateral-veral-pedicle-screw-fixation-combined-with-transforaminal-lumbar-interbody-fusion-rsus-bilatefor-the-treatment-of-low-lumbar-degenerative-disc-diseases-analysis-of-clinical-and-radiographic-results
#2
De-Jian Chen, Cong Yao, Quanwei Song, Benyu Tang, Xuqiang Liu, Bin Zhang, Min Dai, Tao Nie, Zongmiao Wan
OBJECTIVE: Our objective was to compare the clinical and radiographic results of unilateral pedicle screw fixation (UPSF) and bilateral pedicle screw fixation (BPSF) after unilateral transforaminal lumbar interbody fusion (TLIF) for the treatment of lumbar degenerative disc diseases (DDD). MATERIALS AND METHODS: 63 patients who underwent UPSF or BPSF combined with unilateral TLIF at L4-L5 or L5-S1 were included in our hospital from 2014-2016. The perioperative outcomes and radiographic results were recorded at preoperative and postoperative follow-up...
April 24, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29671108/comparison-of-pure-lateral-and-oblique-lateral-inter-body-fusion-for-treatment-of-lumbar-degenerative-disk-disease-a-multicentric-cohort-study
#3
Massimo Miscusi, Alessandro Ramieri, Stefano Forcato, Mary Giuffrè, Sokol Trungu, Marco Cimatti, Alessandro Pesce, Pietro Familiari, Amedeo Piazza, Cristina Carnevali, Giuseppe Costanzo, Antonino Raco
PURPOSE: The most effective interbody fusion technique for degenerative disk disease (DDD) is still controversial. The purpose of our study is to compare pure lateral (LLIF) and oblique lateral (OLIF) approaches for the treatment of lumbar DDD from L1-L2 to L4-L5, in terms of clinical and radiological outcomes. MATERIALS AND METHODS: 45 patients underwent lumbar interbody fusion for pure lumbar DDD from  L1-L2 to L4-L5 through LLIF (n = 31, mean age 62.1 years, range 45-78 years) or OLIF (n = 14, mean age 57...
April 18, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29628809/cytokine-involvement-in-biological-inflammation-related-to-degenerative-disorders-of-the-intervertebral-disk-a-narrative-review
#4
REVIEW
Christopher M De Geer
Objective: The purpose of this narrative literature review is to discuss the literature regarding the potential role that cytokines play in degenerative disk disease. Methods: The inclusion criteria were studies that used inflammatory mediators in advancing disk disease processes. Research studies were limited to the last 3 decades that had free full-text available online in English. Exclusion criteria were review articles and articles pertaining to temporomandibular joints and other joints of the body other than the intervertebral disk...
March 2018: Journal of Chiropractic Medicine
https://www.readbyqxmd.com/read/29619122/cervicothoracic-lordosis-can-influence-outcome-after-posterior-cervical-spine-surgery
#5
Albert Vincent Berthier Brasil, Pablo Ramon Fruett da Costa, Antonio Delacy Martini Vial, Gabriel da Costa Barcellos, Eduardo Balverdu Zauk, Paulo Valdeci Worm, Marcelo Paglioli Ferreira, Nelson Pires Ferreira
Background: Previous studies on the correlation between cervical sagittal balance with improvement in quality of life showed significant results only for parameters of the anterior translation of the cervical spine (such as C2-C7 SVA). Objective: We test whether a new parameter, cervicothoracic lordosis , can predict clinical success in this type of surgery. Methods: The focused group involved patients who underwent surgical treatment of cervical degenerative disk disease by the posterior approach, due to myelopathy, radiculopathy or a combination of both...
2018: Open Orthopaedics Journal
https://www.readbyqxmd.com/read/29593901/frequent-benign-nontraumatic-noninflammatory-causes-of-low-back-pain-in-adolescents-mri-findings
#6
Aikaterini Solomou, Pantelis Kraniotis, Aspasia Rigopoulou, Theodore Petsas
Introduction: Low back pain (LBP) is common in children and adolescents. There are many factors that cause LBP, including structural disorders, degenerative changes, Scheuermann's disease, fractures, inflammation, and tumors. Magnetic Resonance Imaging is the gold standard for diagnosing spinal abnormalities and is mandatory when neurological symptoms exist. The study focuses on common MRI findings in adolescents with persistent LBP, without history of acute trauma or evidence of either inflammatory or rheumatic disease...
2018: Radiology Research and Practice
https://www.readbyqxmd.com/read/29573581/automatic-segmentation-of-pigment-deposits-in-retinal-fundus-images-of-retinitis-pigmentosa
#7
Nadia Brancati, Maria Frucci, Diego Gragnaniello, Daniel Riccio, Valentina Di Iorio, Luigi Di Perna
Retinitis Pigmentosa is an eye disease that presents with a slow loss of vision and then evolves until blindness results. The automatic detection of the early signs of retinitis pigmentosa acts as a great support to ophthalmologists in the diagnosis and monitoring of the disease in order to slow down the degenerative process. A large body of literature is devoted to the analysis of Retinitis Pigmentosa. However, all the existing approaches work on Optical Coherence Tomography (OCT) data, while hardly any attempts have been made working on fundus images...
March 17, 2018: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
https://www.readbyqxmd.com/read/29569159/percutaneous-cement-discoplasty-for-the-treatment-of-advanced-degenerative-disk-disease-in-elderly-patients
#8
Carlos Sola, Gaston Camino Willhuber, Gonzalo Kido, Matias Pereira Duarte, Mariana Bendersky, Maximiliano Mereles, Matias Petracchi, Marcelo Gruenberg
PURPOSE: The authors describe a percutaneous technique to treat advanced degenerative disk disease in elderly patients. METHOD: A step-by-step technical description based on our experience in selected cases. RESULT: Postoperative imaging results are presented as well as indications and recommendations. CONCLUSION: Percutaneous discoplasty can result as an alternative minimal invasive strategy for the treatment of advanced degenerative disk disease...
March 23, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29430605/analysis-of-single-cage-position-in-transforaminal-lumbar-interbody-fusion-through-digital-images
#9
Xin Zhao, Chen Chen, Tangjun Zhou, Jie Mi, Lin Du, Zhanrong Kang, Jianming Huang, Kai Zhang, Xiaojiang Sun, Jie Zhao
PURPOSE: The purpose of this study was to investigate the position of single cage inserted using oblique-oriented technique in transforaminal lumbar interbody fusion (TLIF) on digital images of computed tomography (CT). METHODS: From January to August 2015, 44 consecutive patients with degenerative lumbar disease who underwent TLIF in the L4/5 level were retrospectively studied in our department. The single cage was inserted using the oblique-oriented technique; as the main purpose of the study, its position was analyzed using post-operative digital computed tomography images...
May 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29369138/lumbar-degenerative-disease-with-intervertebral-disk-herniation
#10
(no author information available yet)
No abstract text is available yet for this article.
January 2018: Orthopaedic Nursing
https://www.readbyqxmd.com/read/29369137/lumbar-degenerative-disease-with-intervertebral-disk-herniation
#11
Patrick Graham
No abstract text is available yet for this article.
January 2018: Orthopaedic Nursing
https://www.readbyqxmd.com/read/29315121/cervical-total-disk-arthroplasty
#12
Timothy T Roberts, Ryan J Filler, Jason W Savage, Edward C Benzel
In the United States, cervical total disk arthroplasty (TDA) is US Federal Drug Administration (FDA) approved for use in both 1 and 2-level constructions for cervical disk disease resulting in myelopathy and/or radiculopathy. TDA designs vary in form, function, material composition, and even performance in?vivo. However, the therapeutic goals are the same: to remove the painful degenerative/damaged elements of the intervertebral discoligamenous joint complex, to preserve or restore the natural range of spinal motion, and to mitigate stresses on adjacent spinal segments, thereby theoretically limiting adjacent segment disease (ASDis)...
February 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29284234/chemometric-evaluation-of-concentrations-of-trace-elements-in-intervertebral-disc-tissue-in-patient-with-degenerative-disc-disease
#13
Łukasz Kubaszewski, Anetta Zioła-Frankowska, Zuzanna Gasik, Marcin Frankowski, Mikołaj Dąbrowski, Bartłomiej Molisak, Jacek Kaczmarczyk, Robert Gasik
BACKGROUND: The work is designed to uncover the pattern of mutual relation among trace elements and epidemiological data in the degenerated intervertebral disk tissue in humans. Hitherto the reason of the degenerative process is not fully understood. Trace elements are the basic components of the biological compound related both its metabolism as well as environmental exposure. The relation pattern among elements occurs gives new perspective in solving the cause of the disease. MATERIAL AND METHODS: We have analysed trace elements content in the 30 intervertebral disc from 22 patients with degenerative disc disease...
December 23, 2017: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/29283093/anterior-cervical-disc-fusion-does-not-affect-the-presence-of-cervical-vestibular-evoked-myogenic-potential
#14
Ioannis Kastanioudakis, Panagiotis Saravakos, Andreas Zigouris, Vasileios Ragos, Oliver Reichel, Nafsika Ziavra
OBJECTIVE: Cervical spondylosis and cervical disk herniation are the most frequent forms of degenerative disease in the cervical spine. Surgical treatment mainly includes anterior cervical disk fusion. However, information concerning vestibular-evoked myogenic potential (VEMP) recording in patients undergoing cervical spine surgery is limited. The present prospective study aimed to investigate the effect of anterior disk fusion surgery on cervical VEMP (cVEMP) parameters. MATERIALS AND METHODS: Twenty-five patients were enrolled in this study, and 20 patients (10 men and 10 women) completed cVEMP testing...
December 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29227558/rna-sequencing-identifies-gene-regulatory-networks-controlling-extracellular-matrix-synthesis-in-intervertebral-disk-tissues
#15
Scott M Riester, Yang Lin, Wei Wang, Lin Cong, Abdel-Moneim Mohamed Ali, Sun H Peck, Lachlan J Smith, Bradford L Currier, Michelle Clark, Paul Huddleston, William Krauss, Michael J Yaszemski, Mark E Morrey, Matthew P Abdel, Mohamad Bydon, Wenchun Qu, Annalise N Larson, Andre J van Wijnen, Ahmad Nassr
Degenerative disk disease of the spine is a major cause of back pain and disability. Optimization of regenerative medical therapies for degenerative disk disease requires a deep mechanistic understanding of the factors controlling the structural integrity of spinal tissues. In this investigation, we sought to identify candidate regulatory genes controlling extracellular matrix synthesis in spinal tissues. To achieve this goal we performed high throughput next generation RNA sequencing on 39 annulus fibrosus and 21 nucleus pulposus human tissue samples...
December 11, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28948122/a-case-of-persistent-low-back-pain-in-a-young-female-caused-by-a-trauma-induced-schmorl-s-node-in-the-lumbar-spine-five-vertebra
#16
Kurt M Mohty, Divneet Mandair, Brent Munroe, Deborah Baldemor
Physicians are often faced with managing difficult conditions such as chronic lower back pain. Intervertebral disk herniation typically occurs horizontally, leading to impingement of the spinal cord which can potentially cause radicular symptoms or other spinal cord pathologies; however, disk herniations can also occur vertically and extend through the endplate of an adjacent cranial or caudal vertebra: a phenomenon known as a Schmorl's node. Although Schmorl's nodes can be seen in many asymptomatic individuals, they can be a cause of degenerative disk disease and low back pain...
July 21, 2017: Curēus
https://www.readbyqxmd.com/read/28945642/clinical-and-radiologic-comparison-of-minimally-invasive-surgery-with-traditional-open-transforaminal-lumbar-interbody-fusion-a-review-of-452-patients-from-a-single-center
#17
Julian P Price, John M Dawson, James D Schwender, Kurt P Schellhas
STUDY DESIGN: Retrospective analysis of prospective data for parallel, consecutive series of patients (Level III). OBJECTIVE: Compare clinical results and radiographic outcomes of minimally invasive surgery (MIS) versus open techniques for transforaminal lumbar interbody fusion (TLIF). SUMMARY OF BACKGROUND DATA: Minimally invasive techniques allow transforaminal exposure with decreased soft tissue disruption, but the question remains whether surgical and functional outcomes are equivalent to open techniques...
March 2018: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28846710/apparent-diffusion-coefficient-maps-in-the-assessment-of-surgical-patients-with-lumbar-spine-degeneration
#18
Evgenii Belykh, Andrey A Kalinin, Arpan A Patel, Eric J Miller, Michael A Bohl, Ivan A Stepanov, Liudmila A Bardonova, Talgat Kerimbaev, Anton O Asantsev, Morgan B Giers, Mark C Preul, Vadim A Byvaltsev
PURPOSE: To assess the utility of apparent diffusion coefficient (ADC) maps for the assessment of patients with advanced degenerative lumbar spine disease and describe characteristic features of ADC maps in various degenerative lumbar spinal conditions. METHODS: T1-weighted, T2-weighted and diffusion weighted (DWI) MR images of 100 consecutive patients admitted to the spinal surgery service were assessed. ADC maps were generated from DWI images using Osyrix software...
2017: PloS One
https://www.readbyqxmd.com/read/28750870/-impact-of-obesity-in-the-pathophysiology-of-degenerative-disk-disease-and-in-the-morbidity-and-outcome-of-lumbar-spine-surgery
#19
Pedro David Delgado-López, José Manuel Castilla-Díez
Obesity (BMI>30Kg/m2 ) is a pandemic with severe medical and financial implications. There is growing evidence that relates certain metabolic processes within the adipose tissue, preferentially abdominal fat, with a low-intensity chronic inflammatory state mediated by adipokines and other substances that favor disk disease and chronic low back pain. Obesity greatly conditions both the preoperative evaluation and the spinal surgical technique itself. Some meta-analyses have confirmed an increase of complications following lumbar spine surgery (mainly infections and venous thrombosis) in obese subjects...
March 2018: Neurocirugía
https://www.readbyqxmd.com/read/28746177/correlation-between-high-intensity-zone-on-mri-and-discography-in-patients-with-low-back-pain
#20
Huadong Wang, Zhonghai Li, Chunli Zhang, Weisheng Zhang, Li Li, Jidong Guo, Wenwen Wu, Shuxun Hou
The aim of this study was to analyze the correlation between high-intensity zone (HIZ) on magnetic resonance imaging (MRI) of a lumbar disc and positive pain response assessed by discography for the diagnosis and treatment of discogenic low back pain (LBP). Thirty-seven patients aged 21 to 59 years with chronic LBP but without any neurological symptoms or lumbar disc herniation who underwent MRI and subsequent discography were included in this study. During discography, concordant pain was regarded as positive, whereas discordant pain and no pain were regarded as negative...
July 2017: Medicine (Baltimore)
keyword
keyword
49010
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"