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https://www.readbyqxmd.com/read/29139570/distribution-of-segmental-foot-kinematics-in-patients-with-degenerative-joint-disease-of-the-ankle
#1
Karl Canseco, Karen M Kruger, Jessica M Fritz, Katherine A Konop, Sergey Tarima, Richard M Marks, Gerald F Harris
Degenerative joint disease (DJD) of the ankle is a debilitating chronic disease associated with severe pain and dysfunction resulting in antalgic gait alteration. Little information is available about segmental foot and ankle motion distribution during gait in ankle osteoarthritis. The aim of the current study was to dynamically characterize segmental foot and ankle kinematics of patients with severe ankle arthrosis requiring total ankle replacement. This was a prospective study involving 36 (19 M, 17 F) adult patients with a clinical diagnosis of ankle arthrosis ("DJD" group) and 36 (23 M, 13 F) healthy subjects ("Control" group)...
November 15, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29124354/parathyroid-thyroid-and-recurrent-laryngeal-nerve-anatomy-in-an-indian-rhinoceros-rhinoceros-unicornis
#2
R Udelsman, S B Citino, M Prasad, P I Donovan, D V Fredholm
INTRODUCTION: The parathyroid gland was first identified in the Indian rhinoceros in 1849 by Sir Richard Owen. We performed a necropsy in an Indian rhinoceros, recapitulating Owen's dissection and display what appear to be the initial identification of the recurrent laryngeal nerve in situ and the anatomy and histology of the largest rhinoceros parathyroid glands yet identified. MATERIALS AND METHODS: Patrick T. Rhino, a 41-year-old Indian rhinoceros was born in 1974...
November 9, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28877607/levels-of-matrix-degrading-enzymes-and-lubricin-in-patients-with-degenerative-joint-disease-requiring-arthroplasty
#3
Christopher Wanderling, Jeffrey Liles, Elissa Davis, Daniel Schmitt, Stephen Statz, Nil Guler, Debra Hoppensteadt, Jawed Fareed, William Hopkinson
Total joint arthroplasty (TJA) of the hip or knee (THA and TKA) is the primary surgical intervention for individuals with degenerative joint disease (DJD). Although it is commonly thought that shear force on the joint causes the degradation of articular cartilage, it is possible that there are other factors that contribute to the progression of DJD. It is plausible that specific enzymes that degrade the joint are upregulated, or conversely, there is downregulation of enzymes critical for joint lubrication. The aim of this study is to profile collagenase-1, elastase, heparanase, and lubricin levels in patients undergoing TJA in order to determine potential preexisting dysregulation that contributes to the pathogenesis of DJD...
January 1, 2017: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/28764702/characterisation-of-the-correlation-between-standing-lordosis-and-degenerative-joint-disease-in-the-lower-lumbar-spine-in-women-and-men-a-radiographic-study
#4
Kelvin J Murray, Michael R Le Grande, Arantxa Ortega de Mues, Michael F Azari
BACKGROUND: Degenerative joint disease (DJD) in the lumbar spine is a common condition that is associated with chronic low back pain. Excessive loading of lumbar joints is a risk factor for DJD. Changes in lumbar lordosis significantly redistribute the forces of weight-bearing on the facet joints and the intervertebral discs. However, the relationship between lumbar lordosis and DJD has not been characterized in men and women. METHODS: We characterised the correlation between standing lumbar lordosis and DJD in standing radiographic images from 301 adult female and male chiropractic patients...
August 1, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28730147/correlation-between-pain-and-degenerative-bony-changes-on-cone-beam-computed-tomography-images-of-temporomandibular-joints
#5
SunMee Bae, Moon-Soo Park, Jin-Woo Han, Young-Jun Kim
BACKGROUND: The aim of this study was to assess correlation between pain and degenerative bony changes on cone-beam computed tomography (CBCT) images of temporomandibular joints (TMJs). METHODS: Two hundred eighty-three temporomandibular joints with degenerative bony changes were evaluated. Pain intensity (numeric rating scale, NRS) and pain duration in patients with degenerative joint disease (DJD) were also analyzed. We classified condylar bony changes on CBCT into five types: osteophyte (Osp), erosion (Ero), flattening (Fla), subchondral sclerosis (Scl), and pseudocyst (Pse)...
December 2017: Maxillofacial Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28676150/volar-radioscapholunate-arthrodesis-and-distal-scaphoidectomy-after-malunited-distal-radius-fractures
#6
Stefan Quadlbauer, Martin Leixnering, Josef Jurkowitsch, Thomas Hausner, Christoph Pezzei
PURPOSE: The purpose of this study was to assess range of motion (ROM), pain, and incidence of radiographic degenerative joint disease (DJD) after volar radioscapholunate (RSL) arthrodesis and distal scaphoidectomy (DSE) following malunited distal radius fractures (DRF). METHODS: Fourteen patients with malunited DRF and DJD limited to the radiocarpal joint underwent RSL arthrodesis and DSE between 2006 and 2014. These were retrospectively analyzed both clinically and radiologically...
September 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28427725/association-of-mild-leg-length-discrepancy-and-degenerative-changes-in-the-hip-joint-and-lumbar-spine
#7
Kelvin J Murray, Tom Molyneux, Michael R Le Grande, Aurora Castro Mendez, Franz K Fuss, Michael F Azari
OBJECTIVE: The purpose of this study was to evaluate the correlation between mild leg length discrepancy (LLD) and degenerative joint disease (DJD) or osteoarthritis. METHODS: We evaluated standard postural lumbopelvic radiographs from 255 adults (121 women and 134 men) who had presented with spinal pain for chiropractic care. Symmetry of femoral head diameters was used to exclude magnification errors. Pearson's partial correlation was used to control for age and derive effect sizes for LLD on DJD in the hip and lower lumbar motion segments...
June 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28203357/wrist-bone-mineral-density-utility-in-diagnosing-hip-osteoporosis-in-postmenopausal-women
#8
Bina Eftekhar-Sadat, Mostafa Ghavami, Vahideh Toopchizadeh, Masood Ghahvechi Akbari
BACKGROUND: Osteoporosis is a common bone disease that increases with age. Wrist bone mineral density (BMD) has significant correlation with other skeletal sites and it could be used as a diagnostic method for osteoporosis. The purpose of this study was to evaluate the role of wrist BMD in diagnosing osteoporosis in postmenopausal women. METHODS: In this cross-sectional study, 99 postmenopausal women with mean age of 57 ± 6.9 (range 50-76) years were evaluated...
December 2016: Therapeutic Advances in Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28099449/the-use-of-functional-data-analysis-to-evaluate-activity-in-a-spontaneous-model-of-degenerative-joint-disease-associated-pain-in-cats
#9
COMPARATIVE STUDY
Margaret E Gruen, Marcela Alfaro-Córdoba, Andrea E Thomson, Alicia C Worth, Ana-Maria Staicu, B Duncan X Lascelles
INTRODUCTION AND OBJECTIVES: Accelerometry is used as an objective measure of physical activity in humans and veterinary species. In cats, one important use of accelerometry is in the study of therapeutics designed to treat degenerative joint disease (DJD) associated pain, where it serves as the most widely applied objective outcome measure. These analyses have commonly used summary measures, calculating the mean activity per-minute over days and comparing between treatment periods. While this technique has been effective, information about the pattern of activity in cats is lost...
2017: PloS One
https://www.readbyqxmd.com/read/27929228/all-analgesics-are-better-than-placebo-in-patients-with-knee-or-hip-djd
#10
Henry C Barry
No abstract text is available yet for this article.
October 15, 2016: American Family Physician
https://www.readbyqxmd.com/read/27900293/combined-use-of-platelet-rich-plasma-micro-fat-in-sport-and-race-horses-with-degenerative-joint-disease-preliminary-clinical-study-in-eight-horses
#11
Fabrizio Bembo, Julia Eraud, Cecile Philandrianos, Baptiste Bertrand, Alain Silvestre, Julie Veran, Florence Sabatier, Guy Magalon, Jeremy Magalon
BACKGROUND: To assess the safety and potential efficacy of a standardized technique consisting of intra-articular injection of 10 cc of a homogeneous mixed product using autologous micro-fat and platelet rich plasma (PRP) (ratio 1:1) in the carpus or the fetlock joint of sport horses presenting degenerative joint disease (DJD). METHODS: Eight sport horses with DJD confirmed by radiography and ultrasonography and causing lameness and the impossibility to compete were treated...
April 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/27863553/a-comparison-of-serum-and-plasma-cytokine-values-using-a-multiplexed-assay-in-cats
#12
COMPARATIVE STUDY
Margaret E Gruen, Kristen M Messenger, Andrea E Thomson, Emily H Griffith, Hayley Paradise, Shelly Vaden, B D X Lascelles
BACKGROUND: Degenerative joint disease (DJD) is highly prevalent in cats, and pain contributes to morbidity. In humans, alterations of cytokine concentrations have been associated with joint deterioration and pain. Similar changes have not been investigated in cats. Cytokine concentrations can be measured using multiplex technology with small samples of serum or plasma, however, serum and plasma are not interchangeable for most bioassays. Correlations for cytokine concentrations between serum and plasma have not been evaluated in cats...
December 2016: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/27856966/longitudinal-stability-of-common-tmj-structural-disorders
#13
MULTICENTER STUDY
E L Schiffman, M Ahmad, L Hollender, K Kartha, R Ohrbach, E L Truelove, L Zhang, J S Hodges, E Sommers, G C Anderson, Y M Gonzalez, X Guo, J O Look
The longitudinal course of temporomandibular joint (TMJ) disc displacement (DD) and degenerative joint disease (DJD) has never been conclusively described with magnetic resonance imaging and computed tomography, respectively. This 8-y observational study's objective was to assess the longitudinal stability of DD and DJD among 401 subjects. The Validation Project provided baseline measures; follow-up was performed in the TMJ Impact Project. With magnetic resonance imaging, 2 radiologists rendered a consensus diagnosis of normal/indeterminate, DD with reduction, or DD without reduction...
March 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/27814744/hyaluronic-acid-injection-therapy-for-osteoarthritis-of-the-knee-concordant-efficacy-and-conflicting-serious-adverse-events-in-two-systematic-reviews
#14
Claire E O'Hanlon, Sydne J Newberry, Marika Booth, Sean Grant, Aneesa Motala, Margaret A Maglione, John D FitzGerald, Paul G Shekelle
BACKGROUND: The prevalence of knee osteoarthritis (OA)/degenerative joint disease (DJD) is increasing in the USA. Systematic reviews of treatment efficacy and adverse events (AEs) of hyaluronic acid (HA) injections report conflicting evidence about the balance of benefits and harms. We review evidence on efficacy and AEs of intraarticular viscosupplementation with HA in older individuals with knee osteoarthritis and account for differences in these conclusions from another systematic review...
November 4, 2016: Systematic Reviews
https://www.readbyqxmd.com/read/27756494/hip-related-toxicity-after-prostate-radiotherapy-treatment-related-or-coincidental
#15
Michael J Zelefsky, Marisa A Kollmeier, Elan Gorshein, Xin Pei, Marina Torres, Sean McBride, Laura Happersett, Gil'ad N Cohen, Yoshiya Yamada
BACKGROUND AND PURPOSE: To evaluate the incidence and predictors of hip toxicity postradiotherapy for localized prostate cancer. METHODS AND MATERIALS: 4067 prostate cancer patients were treated with external beam radiotherapy (EBRT; n=2569; 63%) or brachytherapy with or without supplemental EBRT (n=1508; 27%). 43% (n=1738) were treated with neo-adjuvant and concurrent ADT and 57% (n=2329) with radiotherapy alone. Hip toxicity was defined as moderate or severe pain upon ambulation with or without the need for hip-revision surgery...
October 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/27405308/radiographic-evaluation-of-intermetatarsal-angle-correction-following-first-mtp-joint-arthrodesis-for-severe-hallux-valgus
#16
R Matthew McKean, Patrick F Bergin, Geoffrey Watson, Siddhant K Mehta, Thom A Tarquinio
BACKGROUND: Arthrodesis is a standard operative treatment for symptomatic arthritis of the first metatarsophalangeal (MTP) joint. Patients with degenerative joint disease (DJD), severe hallux valgus, and metatarsus primus varus may also require fusion of the first MTP joint. An important question in the latter group of patients is whether a proximal first metatarsal osteotomy is required, in addition to the first MTP joint fusion. Our hypothesis was that patients with severe hallux valgus and metatarsus primus varus, treated with first MTP joint arthrodesis alone, would have correction of the first-to-second intermetatarsal angle (1-2 IMA) and hallux valgus angle (HVA) to near population norms, without the addition of a proximal first metatarsal osteotomy...
November 2016: Foot & Ankle International
https://www.readbyqxmd.com/read/27334504/a-feline-specific-anti-nerve-growth-factor-antibody-improves-mobility-in-cats-with-degenerative-joint-disease-associated-pain-a-pilot-proof-of-concept-study
#17
RANDOMIZED CONTROLLED TRIAL
M E Gruen, A E Thomson, E H Griffith, H Paradise, D P Gearing, B D X Lascelles
BACKGROUND: Neutralizing antibodies against nerve growth factor (NGF) are analgesic in rodent models, naturally occurring degenerative joint disease (DJD) pain in dogs, and chronic pain in humans. OBJECTIVES: To evaluate the efficacy of a fully felinized anti-NGF antibody (NV-02) for the treatment of DJD pain and mobility impairment in cats. ANIMALS: Thirty-four client-owned cats with DJD-associated pain and mobility impairment. METHODS: In a placebo-controlled, pilot, masked clinical study, cats were randomized to a single treatment with NV-02 (0...
July 2016: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/27175844/hyaluronic-acid-equivalent-to-sham-injections-in-patients-with-knee-djd
#18
Henry C Barry
No abstract text is available yet for this article.
April 15, 2016: American Family Physician
https://www.readbyqxmd.com/read/27134560/-18-f-sodium-fluoride-pet-ct-in-patients-with-prostate-cancer-quantification-of-normal-tissues-benign-degenerative-lesions-and-malignant-lesions
#19
Jorge D Oldan, A Stewart Hawkins, Bennett B Chin
Understanding the range and variability of normal, benign degenerative, and malignant (18)F sodium fluoride ((18)F NaF) positron emission tomography/computed tomography (PET/CT) uptake is important in influencing clinical interpretation. Further, it is essential for the development of realistic semiautomated quantification techniques and simulation models. The purpose of this study is to determine the range of these values in a clinically relevant patient population with prostate cancer. (18)F NaF PET/CT scans were analyzed in patients with prostate cancer (n = 47) referred for evaluation of bone metastases...
May 2016: World Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/27122123/variation-of-skeletal-degenerative-joint-disease-features-in-an-identified-italian-modern-skeletal-collection
#20
Stefania Zampetti, Valentina Mariotti, Nico Radi, Maria Giovanna Belcastro
OBJECTIVES: The objective of this study was to investigate the relationship of degenerative joint disease (DJD) features (marginal lipping, porosity, surface osteophytes, eburnation, and loss of joint morphology) with sex, age, and occupation. MATERIALS AND METHODS: We devised a recording method for scoring the single features in the shoulder, elbow, wrist, hip, knee, and ankle of an Italian skeletal sample of 332 individuals (males = 161, females = 171) of known sex, age, and occupation from the Frassetto collection (Sassari, Sardinia, 19th-20th century)...
August 2016: American Journal of Physical Anthropology
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