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https://www.readbyqxmd.com/read/29781422/spirocerca-vulpis-sp-nov-spiruridae-spirocercidae-description-of-a-new-nematode-species-of-the-red-fox-vulpes-vulpes-carnivora-canidae
#1
Alicia Rojas, Gloria Sanchis-Monsonís, Amer Alić, Adnan Hodžić, Domenico Otranto, Daniel Yasur-Landau, Carlos Martínez-Carrasco, Gad Baneth
Previous studies have reported nematodes of the Spirocercidae family in the stomach nodules of red foxes (Vulpes vulpes) described as Spirocerca sp. or Spirocerca lupi (Rudolphi, 1819). We characterized spirurid worms collected from red foxes and compared them to S. lupi from domestic dogs by morphometric and phylogenetic analyses. Nematodes from red foxes differed from S. lupi by the presence of six triangular teeth-like buccal capsule structures, which are absent in the latter. Additionally, in female worms from red foxes, the distance of the vulva opening to the anterior end and the ratio of the glandular-to-muscular oesophagus lengths were larger than those of S...
May 21, 2018: Parasitology
https://www.readbyqxmd.com/read/29752810/a-prospective-study-of-female-genital-chronic-graft-versus-host-disease-symptoms-signs-diagnosis-and-treatment
#2
Eva Smith Knutsson, Yvonne Björk, Anna-Karin Broman, Lotti Helström, Malin Nicklasson, Mats Brune, Karin Sundfeldt
INTRODUCTION: Female genital chronic graft-versus-host disease (cGvHD) is a complication of allogeneic hematopoietic cell transplantation (alloHCT) for blood malignancies. Unattended inflammation and fibrosis in the vulva and vagina may lead to total vaginal stenosis. The course and treatment of genital cGvHD was observed in this population-based prospective study. MATERIAL AND METHODS: Women (n = 41) receiving alloHCT in 2005-2010 were examined before and at 3, 6, 9, 12, 18, 24, 30, and 36 months post-transplant...
May 12, 2018: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29750707/secondary-tumors-of-the-gynecologic-tract-a-clinicopathologic-analysis
#3
Georgia Karpathiou, Celine Chauleur, Sirine Hathroubi, Michel Peoc'h
Although the spread of extragenital tumors to individual female genital tract organs, particularly the ovary, has been much studied, histologic data with regard to secondary tumors involving the whole gynecologic tract are largely lacking. Thus, the aim of the study was to investigate the pathologic and clinical features of these tumors in order to better understand their features. This is a retrospective study of 196 secondary lesions involving the gynecologic tract. The parameters studied were the primary site, its histologic type and grade, the presence of mucous production, the type of secondary involvement, defined as distant metastasis, direct extension or locoregional recurrence, and the time to metastasis...
May 10, 2018: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/29747272/-analysis-of-proliferative-lesions-of-haematopoietic-and-lymphoid-tissue-in-the-female-productive-tract
#4
D B Chen, H Zhang, Y H Zhang, Y Wang, Q J Song, S M Yang, H Cui, Y Zhao, X Z Fang, D H Shen
Objective: To study the clinicopathologic features, diagnosis and differential diagnosis of tumors of haematopoietic and lymphoid tissue in the female productive tract. Methods: Eleven cases of myeloid sarcoma and leukemia, 9 of non Hodgkin lymphoma (NHL) , 13 of cervical lymphoma-like lesions were selected from Peking University People's Hospital from January 2006 to August 2017. According to WHO classification of tumors of haematopoietic and lymphoid tissues (2008) and updated classification(2016), the cases were studied by microscopy, immunohistochemistry and in situ hybridization...
April 25, 2018: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/29745285/p16-expression-in-extramammary-paget-s-disease-of-the-vulva-and-scrotum-is-not-human-papillomavirus-related
#5
Khaleel I Al-Obaidy, Chia-Sui Kao, Muhammad T Idrees
INTRODUCTION: Extramammary Paget disease (EMPD) of the vulva has been shown to express p16 by immunohistochemistry (IHC), however, p16 expression in the vulva and scrotum has not been extensively studied in relation to human papillomavirus (HPV) within EMPD of both the vulva and scrotum. DESIGN: Twenty-two cases of EMPD (vulva, 16; scrotum, 6) were found in our laboratory information system. P16 and HPV IHC were performed. Any p16 reactivity less than 10% was considered negative...
May 1, 2018: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29743937/epidemiologic-and-economic-burden-of-hpv-diseases-in-spain-implication-of-additional-5-types-from-the-9-valent-vaccine
#6
Noelia López, Aureli Torné, Agustín Franco, María San-Martin, Elisabet Viayna, Carmen Barrull, Nuria Perulero
Background: A new nonavalent human papillomavirus (HPV) vaccine that includes genotypes 6/11/16/18/31/33/45/52/58 has been recently approved in Spain. A previous study has shown that attributable fraction of HPV related diseases in Spain is consistent with that reported in European and global studies. The aim of the present study was to estimate the annual direct costs associated to the following HPV-related diseases: genital warts, high grade precancerous lesions and cancer of cervix, vulva, vagina, anus and penis and head and neck cancer, caused by genotypes included in the nonavalent (9vHPV) and quadrivalent vaccines (4vHPV), in Spanish men and women...
2018: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/29742173/photodynamic-diagnosis-with-methyl-5-aminolevulinate-in-squamous-intraepithelial-lesions-of-the-vulva-experimental-research
#7
Lea Leufflen, Aurelie Francois, Julia Salleron, Catherine Barlier, Gilles Dolivet, Frederic Marchal, Lina Bezdetnaya
The incidence of the High-grade Squamous Intraepithelial Lesion of the vulva, formerly vulvar intra-epithelial neoplasia is progressively increasing. Today, an early detection and a precise localization of vulvar lesions are still problematic issues, due to the lack of accuracy of the available diagnostic tool. A new approach is the photodynamic diagnosis based on the fluorescence detection of protoporphyrin IX (PpIX) in cancer cells after topical application of a cream of methyl amino-levulinic acid. This study aimed to evaluate the effectiveness of photodiagnosis in order to discriminate the intensity of PpIX fluorescence between vulvar tumor and healthy skin...
2018: PloS One
https://www.readbyqxmd.com/read/29737916/malignant-granular-cell-tumors-the-role-of-electron-microscopy-in-the-definitive-diagnosis-of-an-extremely-aggressive-soft-tissue-neoplasm
#8
Kurt J Knowles, Firas Al-Delfi, Jehan Abdulsattar, Robin Lacour, Destin Black, Shabnum Chaudhery, Elba A Turbat-Herrera
Granular cell tumors (GCTs) are rare soft tissue neoplasms which may be multicentric. The vast majority are benign, however approximately 100 malignant GCTs have been reported, with only 8 originating in the vulva. Malignant GCTs are very aggressive with very poor survival rates. As the diagnosis of malignant GCT carries an extremely poor prognosis, the utilization of EM ensures that the most accurate diagnosis possible can be rendered.
May 8, 2018: Ultrastructural Pathology
https://www.readbyqxmd.com/read/29736798/pd-l1-receptor-expression-in-vulvar-carcinomas-is-hpv-independent
#9
M Choschzick, A Gut, D Fink
PD-L1 (programmed cell death 1 ligand) is expressed on many cancer cells and prevents tumor cell death by blocking T cell activity. PD-L1 overexpression has been reported in squamous cell carcinomas of head and neck and lung cancer. To better understand the role of PD-L1 expression in vulvar cancer, we analyzed PD-L1 expression by immunohistochemistry in 55 well-characterized squamous cell carcinomas of vulva. PD-L1 was found in 72.7% of tumors. 27.3% of vulvar carcinomas showed moderate or strong PD-L1 expression...
May 8, 2018: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/29736730/a-scanning-electron-microscopy-study-of-anisakis-physeteris-molecularly-identified-from-third-stage-larvae-from-fish-to-fourth-stage-larvae-obtained-in-vitro
#10
Dolores Molina-Fernández, Francisco Javier Adroher, Rocío Benítez
The development of the fourth larval stage (L4) of Anisakis physeteris was studied using scanning electron microscopy (SEM), comparing it with third larval stage (L3) recently obtained from the host fish, blue whiting (Micromesistius poutassou), from the western Mediterranean Sea (east coast of Spain, zone FAO 37.1.1). After molting to L4, samples of the parasite were examined at different times in order to observe their development. Following collection of the L4, a small portion was taken from the middle of the larva for molecular identification, confirming in all cases that it was A...
May 7, 2018: Parasitology Research
https://www.readbyqxmd.com/read/29728261/melanoma-of-the-lower-genital-tract-prognostic-factors-and-treatment-modalities
#11
REVIEW
Angiolo Gadducci, Silvestro Carinelli, Maria Elena Guerrieri, Giovanni Damiano Aletti
Primary melanomas originating from the gynecological tract are rare and aggressive cancers. The vulva is the most frequent site (70%), followed by vagina and more rarely by cervix. The clinical outcome of patients with female genital tract melanoma is very poor, with a 5-year overall survival (OS) of 37-50% for vulvar, 13-32% for vaginal, and approximately 10% for cervical melanoma. In this systematic review, we analyzed the pathogenesis and the different factors influencing the prognosis of melanomas of the lower genital tract, with particular emphasis on biologic variables that may influence new therapeutic approaches...
May 1, 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/29727346/imaging-features-of-extramammary-paget-disease-of-the-scrotum-a-case-report
#12
Sang Lim Choi, Sung Bin Park, Eun Sun Lee, Hyun Jeong Park, Jong Beum Lee, Byung Ihn Choi
Extramammary Paget disease (EMPD) is a rare intraepithelial malignancy originating in areas rich in apocrine glands, such as the vulva, perineum, perianal area, scrotum, and penis. A few reports of EMPD involving the scrotum have been described in the literature. However, only few reports have described imaging features observed in patients presenting with EMPD. We report EMPD in a patient showing scrotal involvement, focusing on imaging features, particularly those determined ultrasonographically.
January 5, 2018: Ultrasound Quarterly
https://www.readbyqxmd.com/read/29723364/most-frequent-dermatoses-at-a-vulvar-pathology-outpatient-clinic
#13
Gabriella Cerazi Sartori, Rafaela Tricca Wicher, Flávia Regina Ferreira, Valéria Holmo Batista
The vulva corresponds to the external female genitalia. Special features of this region favor a wide range of diseases, whose knowledge allows for better clinical management, impacting on the quality of life. This is a cross-sectional and descriptive study carried out at a vulvar pathology outpatient clinic, between May and December/ 2015. Data obtained from a standard form included demographic parameters, habits, and vulvar dermatosis and allowed to identify the epidemiological profile of patients with vulvar dermatosis treated in this outpatient clinic and to determine the most prevalent dermatoses...
March 2018: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29715633/the-detoxification-effect-of-vitamin-c-on-zearalenone-toxicity-in-piglets
#14
Yang Su, Yuchen Sun, Daxin Ju, Siying Chang, Baoming Shi, Anshan Shan
Zearalenone (ZEN), one of the more virulent mycotoxins occurred in various cereals and feed during recent decades and made serious health hazards to plants, animals and humans. Vitamin C (Vc) has been shown to be an effective antidote to zearalenone. In this paper, the effects of diets containing zearalenone on the growth performance, genital organ and immunoglobulin of weaning piglets and the toxicity alleviation of vitamin C were studied. Piglets were weaned at 21 days of age and 32 healthy female hybrid weaning piglets (Duroc × Landrace × Large white) with a mean weight of 12...
April 28, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29710286/carvedilol-for-treatment-of-red-vulva-syndrome
#15
Carla Hajj, Nakhle Ayoub
No abstract text is available yet for this article.
April 25, 2018: JAMA Dermatology
https://www.readbyqxmd.com/read/29706578/does-depth-matter-factors-affecting-choice-of-vulvoplasty-over-vaginoplasty-as-gender-affirming-genital-surgery-for-transgender-women
#16
David Jiang, Jonathan Witten, Jens Berli, Daniel Dugi
BACKGROUND: Gender-affirming vaginoplasty aims to create the external female genitalia (vulva) as well as the internal vaginal canal; however, not all patients desire nor can safely undergo vaginal canal creation. AIM: Our objective is to describe the factors influencing patient choice or surgeon recommendation of vulvoplasty and to assess the patient's satisfaction with this choice. METHODS: Gender-affirming genital surgery consults were reviewed from March 2015 until December 2017, and patients scheduled for or who had completed vulvoplasty were interviewed by telephone...
April 26, 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29696442/the-best-of-both-worlds-a-hybrid-approach-for-optimal-pre-and-intraoperative-identification-of-sentinel-lymph-nodes
#17
G H KleinJan, E van Werkhoven, N S van den Berg, M B Karakullukcu, H J M A A Zijlmans, J A van der Hage, B A van de Wiel, T Buckle, W M C Klop, S Horenblas, R A Valdés Olmos, H G van der Poel, F W B van Leeuwen
PURPOSE: Hybrid image-guided surgery technologies such as combined radio- and fluorescence-guidance are increasingly gaining interest, but their added value still needs to be proven. In order to evaluate if and how fluorescence-guidance can help realize improvements beyond the current state-of-the-art in sentinel node (SN) biopsy procedures, use of the hybrid tracer indocyanine green (ICG)-99m Tc-nancolloid was evaluated in a large cohort of patients. PATIENTS AND METHODS: A prospective trial was conducted (n = 501 procedures) in a heterogeneous cohort of 495 patients with different malignancies (skin malignancies, oral cavity cancer, penile cancer, prostate cancer and vulva cancer)...
April 25, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29692512/a-neglected-reddish-penile-patch-a-wolf-in-sheep-s-clothing
#18
Pragatheeswarane Murugavaithianathan, Sudheer K Devana, Kim Vaiphei, Ravimohan Mavuduru, Girdhar S Bora
Microinvasive squamous cell carcinoma (SCC) is a known premalignant lesion of carcinoma cervix. It is also reported from other sites such as the oral cavity, larynx, and vulva. Microinvasive SCC is very rarely reported from the penis. We report the occurrence of microinvasive SCC in a long-standing erythematous lesion of glans penis in a patient, with extensive metastasis. We emphasize the need for awareness among patients and urologists about the premalignant lesions of penis and prompt treatment of such lesions to prevent possible spread of the disease...
April 2018: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/29690108/two-rare-species-of-tylenchids-discotylenchus-biannulatus-n-sp-and-labrys-chinensis-qing-bert-2018-nematoda-tylenchidae-from-western-iran
#19
Ehsan Konani, Yousef Panahandeh, Ebrahim Pourjam, Sergio Álvarez-Ortega, Majid Pedram
Two rare species of the family Tylenchidae are described and illustrated based on morphological and morphometric characters. Scanning electron microscope (SEM) studies provided details of anterior end structures, helpful in generic identification of the studied populations. Discotylenchus biannulatus n. sp. is characterized by its dorso-ventrally flattened smooth cephalic region having two proximal annuli and a rectangular perioral disc, short longitudinal amphidial slits, lateral field with four incisures, stylet 9-10 μm long, with the conus shorter than half the total stylet length and with posteriorly directed knobs, well-developed median bulb, mono-prodelphic reproductive system with rounded empty spermatheca and short postvulval uterine sac (PUS), and filiform tail with pointed end...
April 23, 2018: Zootaxa
https://www.readbyqxmd.com/read/29690073/description-of-two-new-and-two-known-species-of-the-genus-tylencholaimellus-cobb-in-m-v-cobb-1915-nematoda-dorylaimida-tylencholaimoidea
#20
Wasim Ahmad, Sumaya Ahad
Two new and two known species of the dorylaimid nematode genus Tylencholaimellus Cobb in M.V. Cobb, 1915 are described and illustrated. Tylencholaimellus arabicus sp. n. collected from Saudi Arabia is characterized by having small sized body (L= 0.66-0.83 mm); outer cuticle with distinct transverse striations; inner layer thick with fine transverse striations; lip region offset by a deep constriction, inner liplets slightly raised; odontostyle 15-17 µm, odontophore 8-10 µm, combined length 25-26 μm; female genital system mono-opisthodelphic; anterior uterine sac 0...
January 25, 2018: Zootaxa
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