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https://www.readbyqxmd.com/read/28087025/dermoscopy-of-isolated-syringoma-of-the-vulva
#1
Monica Corazza, Alessandro Borghi, Sara Minghetti, Paola Ferron, Annarosa Virgili
No abstract text is available yet for this article.
February 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28081287/current-insights-into-the-aetiology-pathobiology-and-management-of-local-disease-recurrence-in-squamous-cell-carcinoma-of-the-vulva-a-review-paper
#2
REVIEW
Jason Yap, Danielle O'Neill, Sangeetha Nagenthiran, Christopher Dawson, David Luesley
Squamous cell carcinoma of the vulva is predominantly a disease of the elderly, where the mainstay of treatment is radical surgery. Local vulval recurrence (LVR) is a significant problem for these patients, and the rates of recurrence have not improved over the last three decades. Disappointingly, we still lack an understanding of how LVRs develop and the best approach to prevent and manage the condition. This review discusses recent insights into the key prognostic factors that influence the risk of recurrence, focusing on the role of tumour-adjacent non-neoplastic epithelial disorders, which are thought to play a causative role...
January 12, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28079968/salud-vaginal-y-de-la-vulva
#3
(no author information available yet)
No abstract text is available yet for this article.
January 12, 2017: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/28063696/association-of-post-treatment-positron-emission-tomography-with-locoregional-control-and-survival-after-radiation-therapy-for-squamous-cell-carcinoma-of-the-vulva
#4
Yuan James Rao, Comron Hassanzadeh, Anupama Chundury, Caressa Hui, Barry A Siegel, Farrokh Dehdashti, Todd DeWees, Daniel Mullen, Matthew A Powell, David G Mutch, Julie K Schwarz, Perry W Grigsby
BACKGROUND/PURPOSE: The aim of this study was to investigate the use of post-treatment F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) for vulvar cancer and compare metabolic response to clinical outcomes. MATERIALS/METHODS: This retrospective study included 21 patients with vulvar squamous cell carcinoma treated with curative-intent radiation between 2007 and 2015. All patients received intensity-modulated radiation treatment (IMRT), a pre-treatment FDG/PET-CT, and a post-treatment FDG-PET/CT performed at a median time of 3months post-IMRT...
January 4, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28062989/angiostoma-norvegicum-n-sp-nematoda-angiostomatidae-a-parasite-of-arionid-slugs-in-norway
#5
Jenna L Ross, Solveig Haukeland, Bjørn A Hatteland, Elena S Ivanova
Angiostoma norvegicum n. sp. (Angiostomatidae) is described from the oesophagus, crop and the buccal mass of five species of slugs of the family Arionidae, Arion vulgaris (Moquin-Tandon), Arion ater (L.), Arion fasciatus (Nilsson), Arion fuscus (Müller) and Arion rufus/Arion ater hybrid), collected throughout Norway. Angiostoma norvegicum n. sp. was found parasitising arionids at seven of the 30 sample sites examined (23.3%), and 9.9% of all Arion spp. were infected with this nematode. The new species is characterised by its large size (4...
January 2017: Systematic Parasitology
https://www.readbyqxmd.com/read/28061900/a-clitoral-verrucous-carcinoma-in-an-area-of-lichen-planus-has-aggressive-features
#6
Wiebren A A Tjalma, Vasiliki Siozopoulou, Manon T Huizing
BACKGROUND: Verrucous carcinoma of the vulva is extremely rare. It is a slow growing, low malignant variant of a squamous cell carcinoma with a cauliflower appearance. Women with lichen planus have an increased risk of developing vulval cancer. CASE PRESENTATION: A 79-year-old woman consulted for vulval itching. On clinical examination, a 3-cm large verrucous clitoral cancer in an area of lichen planus was seen. Based on her last clinical examination, the growth was estimated to be 1 cm(2) per month with an invasion depth after 6 months of 5 mm...
January 6, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28059857/risk-for-cancer-among-people-living-with-aids-1997-2012-the-s%C3%A3-o-paulo-aids-cancer-linkage-study
#7
Luana F Tanaka, Maria R D O Latorre, Eliana B Gutierrez, Maria P Curado, Guenter Froeschl, Christian Heumann, Karl-Heinz Herbinger
Previous studies have reported an increased risk for certain types of cancer in the HIV-infected population. The aim of this study was to assess the risk for cancer in people with AIDS (PWA) in comparison with the general population in São Paulo (Brazil), between 1997 and 2012. A population-based registry linkage study was carried out to assess the risk for cancer, using a standardized incidence ratio (SIR) approach. A total of 480 102 person-years, of which 337 941 (70.4%) person-years were men, were included in the analysis...
January 4, 2017: European Journal of Cancer Prevention
https://www.readbyqxmd.com/read/28059556/effects-of-genital-response-measurement-device-and-stimulus-characteristics-on-sexual-concordance-in-women
#8
Katrina N Bouchard, Meredith L Chivers, Caroline F Pukall
Investigations of sexual concordance suggest that, on average, women exhibit a low, positive correlation between their subjective sexual arousal and genital response. However, this relationship appears to be stronger, on average, when genital response is measured via the external tissues of the vulva than within the vagina walls. Given the methodological variations, such as stimulus content and duration, in studies of vulvar and vaginal concordance, direct comparisons between individual studies are limited...
January 6, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/28050386/juvenile-xanthogranuloma-in-vulva-of-a-10-year-old-child
#9
Barkha Gupta, Surekha Yadav, Nita Khurana, Manish Sharma
A 10-year-old child presented with asymptomatic, well-circumscribed nodule in the vulva. Excision biopsy showed features of classic Juvenile Xanthogranuloma (JXG) which is a rare benign disorder of non-langerhans' cell group of histiocytic proliferative diseases. The presentation of this lesion as vulval nodule is extremely rare and the extensive literature search revealed only handful of cases of vulval xanthogranuloma that too in an adult age group. The lesion is however prognostically favourable and should be kept in mind as one of the differential diagnosis of the vulval nodule...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28040722/surgical-management-of-vulvar-cancer
#10
REVIEW
Thanh H Dellinger, Amy A Hakim, Stephen J Lee, Mark T Wakabayashi, Robert J Morgan, Ernest S Han
Vulvar cancer is a rare malignancy with high curability in early-stage disease, yet poor outcomes for advanced-stage and recurrent disease. Surgical management is at the cornerstone of treatment for most vulvar cancers, and includes conservative and radical resection of the primary vulvar tumor and excision of local lymph nodes, which are major prognostic factors and drive adjuvant treatment. This review summarizes the surgical management of primary squamous cell carcinoma of the vulva, specifically initial treatment guidelines by stage, based on the 2017 NCCN Clinical Practice Guidelines in Oncology for Vulvar Cancer...
January 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/28034465/locally-advanced-vulva-cancer-a-single-centre-review-of-anovulvectomy-and-a-systematic-review-of-surgical-chemotherapy-and-radiotherapy-alternatives-is-an-international-collaborative-rct-destined-for-the-too-difficult-to-do-box
#11
REVIEW
Rachel Louise O'Donnell, Leen Verleye, Nithya Ratnavelu, Khadra Galaal, Ann Fisher, Raj Naik
INTRODUCTION: Treatment of locally advanced vulva cancer (LAVC) remains challenging. Due to the lack of randomised trials many questions regarding the indications for different treatment options and their efficacy remain unanswered. METHODS: In this retrospective study we provide the largest published series of LAVC patients treated with anovulvectomy, reporting oncological outcomes and morbidity. Additionally, a systematic literature review was performed for all treatment options 1946-2015...
December 26, 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/28009610/alveolar-soft-part-sarcoma-of-the-female-genital-tract-a-morphologic-immunohistochemical-and-molecular-cytogenetic-study-of-10-cases-with-emphasis-on-its-distinction-from-morphologic-mimics
#12
J Kenneth Schoolmeester, Joseph Carlson, Gary L Keeney, Karen J Fritchie, Esther Oliva, Robert H Young, Marisa R Nucci
Alveolar soft part sarcoma (ASPS) is a morphologically distinctive neoplasm of unknown differentiation that bears a characteristic gene fusion involving ASPSCR1 and TFE3. ASPS can occur in the female genital tract, but is rare. Eleven cases with an initial diagnosis of ASPS at female genital tract sites were evaluated for their morphologic features and immunoprofile using a panel of antibodies (TFE3, HMB45, melan-A, smooth muscle actin, desmin, and h-Caldesmon). In addition, the presence of TFE3 rearrangement and subsequent ASPSCR1-TFE3 fusion were determined by fluorescence in situ hybridization...
December 22, 2016: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28007841/a-network-of-chromatin-factors-is-regulating-the-transition-to-postembryonic-development-in-caenorhabditis-elegans
#13
Peter Erdelyi, Xing Wang, Marina Suleski, Chantal Wicky
Mi2 proteins are evolutionarily conserved, ATP-dependent chromatin remodelers of the CHD family that play key roles in stem cell differentiation and reprogramming. In Caenorhabditis elegans the let-418 gene encodes one of the two Mi2 homologs which is part of at least two chromatin complexes, namely the Nucleosome Remodeling and histone Deacetylase (NuRD) complex and the MEC complex, and functions in larval development, vulva morphogenesis, lifespan regulation and cell fate determination. To explore the mechanisms involved in the action of LET-418/Mi2 we performed a genome wide RNAi screen for suppressors of early larval arrest associated with let-418 mutations...
December 22, 2016: G3: Genes—Genomes—Genetics
https://www.readbyqxmd.com/read/28002312/committee-opinion-no-686-breast-and-labial-surgery-in-adolescents
#14
(no author information available yet)
The obstetrician-gynecologist may receive requests from adolescents and their families for advice, surgery, or referral for conditions of the breast or vulva to improve appearance and function. Appropriate counseling and guidance of adolescents with these concerns require a comprehensive and thoughtful approach, special knowledge of normal physical and psychosocial growth and development, and assessment of the physical maturity and emotional readiness of the patient. Individuals should be screened for body dysmorphic disorder...
January 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28002307/committee-opinion-no-686-summary-breast-and-labial-surgery-in-adolescents
#15
(no author information available yet)
The obstetrician-gynecologist may receive requests from adolescents and their families for advice, surgery, or referral for conditions of the breast or vulva to improve appearance and function. Appropriate counseling and guidance of adolescents with these concerns require a comprehensive and thoughtful approach, special knowledge of normal physical and psychosocial growth and development, and assessment of the physical maturity and emotional readiness of the patient. Individuals should be screened for body dysmorphic disorder...
January 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28002209/value-of-specialist-pathology-review-in-a-single-statewide-gynecologic-cancer-service
#16
Jerome Melon, Yee Leung, Stuart G Salfinger, Jason Tan, Ganendra Mohan, Paul A Cohen
OBJECTIVE: A case review by specialist diagnostic pathologists as part of a Gynecologic Oncology Multi-disciplinary Tumor group has the potential to influence the management of patients with cancer. The primary aim of this study was to determine the frequency of diagnostic discrepancies between the initial (nonspecialist) and final pathological diagnoses in cases referred to the Gynecologic Oncology Tumor Conference (TC) in Western Australia and the impact of such revised diagnosis on clinical management...
January 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/27998445/-progression-of-vulva-intraepithelial-neoplasia-grade-%C3%A2-to-vulva-cancer-a-case-report
#17
W H Zhang, P Bai, S M Li, H Sun
No abstract text is available yet for this article.
November 23, 2016: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/27994832/mayo-clinic-cancer-center-experience-of-metastatic-extramammary-paget-disease-1998-2012
#18
Leslie Padrnos, Nina Karlin, Thorvardur R Halfdanarson
Extramammary Paget disease (EMPD) is a rare cutaneous malignancy. The most common presentation of EMPD is the vulva followed by perianal involvement. Most cases are localized to the dermis with treatment focused on surgery, topical treatment or radiotherapy. Recurrence is frequent despite therapies utilized. Metastatic extramammary Paget disease is uncommon and, as such, standard treatment guidelines do not exist. This study sought to evaluate the treatment regimens and outcomes of patients treated at a Mayo Clinic Center from 1998-2012...
November 17, 2016: Rare Tumors
https://www.readbyqxmd.com/read/27992931/extrapelvic-endometriosis
#19
Anne C Davis, Jeffrey M Goldberg
Extrapelvic endometriosis is a rare and complex phenomenon. The pathologic mechanism of intrapelvic endometriosis is generally accepted as being largely due to retrograde menstruation through the fallopian tubes; however, the mechanism by which extrapelvic endometriosis forms has proven to be much more elusive. This article reviews the pathophysiology, clinical signs and symptoms, diagnostic techniques, and treatment recommendations for extrapelvic endometriosis of the umbilicus, abdominal wall, thorax, and vulva...
December 19, 2016: Seminars in Reproductive Medicine
https://www.readbyqxmd.com/read/27990743/punishment-of-minor-female-genital-ritual-procedures-is-the-perfect-the-enemy-of-the-good
#20
Allan J Jacobs, Kavita Shah Arora
Female genital alteration (FGA) is any cutting, removal or destruction of any part of the external female genitalia. Various FGA practices are common throughout the world. While most frequent in Africa and Asia, transglobal migration has brought ritual FGA to Western nations. All forms of FGA are generally considered undesirable for medical and ethical reasons when performed on minors. One ritual FGA procedure is the vulvar nick (VN). This is a small laceration to the vulva that does not cause morphological changes...
December 19, 2016: Developing World Bioethics
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