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https://www.readbyqxmd.com/read/28546667/adenoid-cystic-carcinoma-of-vulva-11%C3%A2-years-single-institution-experience
#1
Leena Rose Johnson, Rema Prabhakaran Nair, Suchetha Sambasivan, Rari P Mony, Jayapriya Gangadharan, Aswin Kumar, Iqbal M Ahamed
INTRODUCTION: Adenoid cystic carcinoma of vulva (ACC-vulva) is an extremely rare entity with <100 cases reported in the literature so far. OBJECTIVE: To study the clinical profile and outcome of ACC-vulva treated at a tertiary cancer care centre in South India. METHODS: This is a retrospective, record-based study of histopathologically confirmed cases of ACC-vulva treated at our centre from January 2005 to March 2016. RESULTS: Only four patients were diagnosed with ACC-vulva during the 11-year period under study...
June 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/28543379/idiopathic-lymphoplasmacellular-mucositis-of-the-lips-a-case-report-and-review-of-the-literature
#2
Ren-Feng Liu, Chun-Bing Chen, Tseng-Tong Kuo, Wen-Hung Chung
Idiopathic lymphoplasmacellular mucositis (ILPM) is a group of disorders histologically characterized by dense infiltrates of lymphocytes and plasma cells in submucosa. These lesions are initially observed on the glans penis and vulva, and later on buccal mucosa, lips, gingiva, tongue, epiglottis, larynx, and other mucosal surfaces have also been reported. We have reviewed the previously reported cases of ILPM with lip involvement, outlining the clinical presentation, treatment and outcome of the entity to date...
May 23, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28541878/dermatosis-papular-acantol%C3%A3-tica-de-la-vulva-con-buena-respuesta-a-tacr%C3%A3-limus-t%C3%A3-pico
#3
Miguel Angel Flores-Terry, Pamela Zamberk Majlis, Monserrat Franco-Muñoz, Elena Vera-Iglesias, Mónica García-Arpa, Francisco Martín-Dávila
Papular acantholytic dermatosis of the vulva is a rare, chronic disorder and is an entity that remains to be fully understood. It shares clinical and histopathological overlap with Darier disease and Hailey-Hailey disease. We describe a 30-year-old woman with papular acantholytic dermatosis of the vulva. The lesions consisted of whitish papules and erosions on the labia majora. Histologically, there was hyperkeratosis and focal parakeratosis with acantholytic and dyskeratotic cells. She did not respond completely to topical steroids but clinical improvement occurred after the use of topical tacrolimus...
April 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28541790/long-lasting-increased-risk-of-human-papillomavirus-related-carcinomas-and-premalignancies-after-cervical-intraepithelial-neoplasia-grade-3-a-population-based-cohort-study
#4
Renée M F Ebisch, Dominiek W E Rutten, Joanna IntHout, Willem J G Melchers, Leon F A G Massuger, Johan Bulten, Ruud L M Bekkers, Albert G Siebers
Purpose The aim of this study was to determine the risk of human papillomavirus (HPV)-related carcinomas and premalignancies in women diagnosed with cervical intraepithelial neoplasia grade 3 (CIN3). Knowledge of this risk is important to preventing the development and progression of other HPV-related premalignancies and carcinomas, by considering prophylactic HPV vaccination and/or by paying increased attention to other HPV-related carcinomas and premalignancies when CIN3 is identified. Methods Women diagnosed with a CIN3 between 1990 and 2010 were identified from the Dutch nationwide registry of histopathology and cytopathology (PALGA) and matched with a control group of women without CIN3...
May 25, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28538888/verrucous-carcinoma-of-the-vulva-diagnosis-and-treatment
#5
Adriana Bittencourt Campaner, Fernanda de Araujo Cardoso, Gustavo Leme Fernandes, John Verrinder Veasey
Vulvar cancer accounts for less than 1% of malignancies in women. Verrucous carcinoma of the vulva is a rare histological variation, comprising less than 1% of vulvar cancer cases. Although it is characterized as being locally invasive, the condition is not associated with metastatic spreading. Lesions present in the form of a verrucous, ulcerated, and bleeding tumor that can reach large dimensions. This type of tumor can be mistaken for condylomata, both macroscopically and microscopically. We report the case of an 81-year-old patient with a large vulvar tumor presented for eight years, initially considered as a Buschke-Löwenstein tumor...
March 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28538409/a-case-report-of-pedigree-of-a-homozygous-mutation-of-the-steroidogenic-acute-regulatory-protein-causing-lipoid-congenital-adrenal-hyperplasia
#6
Rong Fu, Lin Lu, Jun Jiang, Min Nie, Xiaojing Wang, Zhaolin Lu
RATIONALE: Lipoid congenital adrenal hyperplasia (LCAH) is extremely rare, but is the most fatal form of congenital adrenal hyperplasia resulting from mutations in the steroidogenic acute regulatory protein (STAR) gene. LCAH arises from severe defects in the conversion of cholesterol to pregnenolone, the precursor of all steroids. PATIENT CONCERNS: A case was reported that an 11-month-old Chinese girl who presented with a sex development disorder and hyponatremia...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28531205/cost-analysis-of-human-papillomavirus-related-cervical-diseases-and-genital-warts-in-swaziland
#7
Themba G Ginindza, Benn Sartorius, Xolisile Dlamini, Ellinor Östensson
BACKGROUND: Human papillomavirus (HPV) has proven to be the cause of several severe clinical conditions on the cervix, vulva, vagina, anus, oropharynx and penis. Several studies have assessed the costs of cervical lesions, cervical cancer (CC), and genital warts. However, few have been done in Africa and none in Swaziland. Cost analysis is critical in providing useful information for economic evaluations to guide policymakers concerned with the allocation of resources in order to reduce the disease burden...
2017: PloS One
https://www.readbyqxmd.com/read/28529603/risk-factors-for-cervical-intraepithelial-neoplasia-and-cervical-cancer-in-chinese-women-large-study-in-jiexiu-shanxi-province-china
#8
Zhilian Wang, Jintao Wang, Jinrong Fan, Weihong Zhao, Xin Yang, Lingmei Wu, Dongyan Li, Ling Ding, Wei Wang, Junjie Xu, Michelle Stram, Chengquan Zhao, Min Hao
We aimed to investigate the risk factors for cervical intraepithelial neoplasia (CIN) in Jiexiu, Shanxi Province, China. Twenty thousand eligible married women (age: 18-65 years) were administered with a questionnaire on potential risk factors for CIN and underwent liquid based Pap test. All women with abnormal cytological results underwent colposcopy with biopsy. Based on the biopsy pathology results, women were then assigned to either study group (with CIN) or control group (negative for histological results and volunteered to participate in the follow up study)...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28528690/clinical-relevance-and-implications-of-hpv-induced-neoplasia-in-different-anatomical-locations
#9
REVIEW
Elena Sophie Prigge, Magnus von Knebel Doeberitz, Miriam Reuschenbach
Human papillomaviruses (HPV) are widespread DNA viruses that can infect epithelial cells of the skin and mucosa. Most HPV infections remain clinically unapparent and clear spontaneously. In few cases, however, HPV infections persist and can cause benign and malignant neoplasms at different anatomic locations. Malignant HPV-induced neoplasms are caused by distinct types of HPV (oncogenic or high-risk (HR) HPV types) and present in the anogenital (anus, penis, uterine cervix, vagina and vulva) and head and neck (particularly oropharynx) region...
April 2017: Mutation Research
https://www.readbyqxmd.com/read/28514296/clinicopathological-features-and-differential-diagnosis-of-aggressive-angiomyxoma-of-the-female-pelvis-5-case-reports-and-literature-review
#10
Hong Chen, Hongyan Zhao, Yan Xie, Mulan Jin
Aggressive angiomyxoma (AAM) is a rare mesenchymal tumor that usually occurs in the pelvis and perineum of young females. AAM can simulate Bartholin's gland cyst, abscess, lipoma, simple labial cyst, or other pelvic soft tissue tumors. Here we present five cases of AAM with mean age of 42. The patients mainly presented slow-growing mass in the abdomen and perineum (3 cases in the pelvis, 1 in the vulva, and 1 in the buttock). Color Doppler flow imaging revealed blood flow for the 3 pelvic lesions. Enhanced computed tomography and magnetic resonance imaging of the other 2 cases showed the typical "swirled" or "layered" structure characteristic...
May 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28514239/understanding-women-s-sexual-behaviors-that-may-put-them-at-risk-for-human-papillomavirus-related-neoplasias-what-should-we-ask
#11
Amita Kulkarni, Tram Tran, Christine Luis, Christina A Raker, Beth Cronin, Katina Robison
OBJECTIVES: Human papillomavirus is a multifocal infection that can involve the cervix, vagina, vulva, anus, and oropharynx. Our study aimed to determine whether standard sexual history questions regarding anal intercourse identify women participating in anal-related sexual practices. MATERIALS AND METHODS: A cross-sectional survey was conducted at the dysplasia clinic of a large academic medical center. Women presenting with human papillomavirus-related cervical, vulvar, or vaginal abnormalities were eligible...
May 16, 2017: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/28511222/cellular-angiofibroma-of-the-spermatic-cord
#12
M Aydin, H Uzuner, E Akgunes, A Bitkin, M Kadihasanoglu
Cellular angiofibromas are rare, slow-growing mesenchymal tumours, most often localised in the vulva and perineum of women. We present a case of a 60-year-old male with a 7-cm large cellular angiofibroma in the inguinal canal extending toward the testis, detected after inguinal herniorraphy. Inguinal orchiectomy was performed and the pathology report revealed a cellular angiofibroma containing a lot of mast cells in the stroma, which was collagenised with spindle-shaped cells and characterised by hyalinised vascular structures...
April 2017: Aktuelle Urologie
https://www.readbyqxmd.com/read/28510222/primary-ectopic-breast-cancer-of-the-vulva-treated-with-local-excision-of-the-vulva-and-sentinel-lymph-node-biopsy-a-case-report
#13
Takayuki Ishigaki, Yasuo Toriumi, Ryouko Nosaka, Rei Kudou, Yoshimi Imawari, Makiko Kamio, Hiroko Nogi, Hisashi Shioya, Hiroshi Takeyama
Primary breast cancer fairly infrequently occurs in ectopic breast tissue, and primary ectopic breast cancer of the vulva is particularly rare. Only 26 cases have been published in the English-language literature, and there has been no report of primary breast carcinoma of the vulva in Japan. We report a rare case of primary ectopic breast cancer of the vulva that was treated with local excision of the vulva and sentinel lymph node biopsy (SLNB). The patient was a 72-year-old woman who had noticed a right vulvar tumor 10 years earlier...
December 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28509325/an-alternative-approach-to-gynecological-wound-healing
#14
Jakub Rzepka, Katarzyna Mosoń, Romuald Dębski
An 89-year-old woman was reffered to our Clinic with vulvar cancer. She also suffered from obesity [with body mass index (BMI) 35 kg/m2], persistent hypertension, diabetes mellitus type 2 treated with oral medications. In 2015 she underwent a surgery due to endometrial carcinoma. Total abdominal hysterectomy with bilateral salphingoophorectomy, omentectomy and pelvical node dissection was performed (histopathology revealed adenocarcinoma serosum G2; FIGO stage Ib). In January 2016 after vulvar ulceration biopsy plano-epithelial squamous vulvar cancer was diagnosed...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28507407/study-on-postpartum-estrus-of-guinea-pigs-cavia-cobaya-using-anredera-cordifolia-leaf-extract
#15
D Wijayanti, E T Setiatin, E Kurnianto
AIM: The purpose of this study was to determine the postpartum estrus cycle of guinea pigs (Cavia cobaya) using Anredera cordifolia leaf extract. MATERIALS AND METHODS: Materials used were 8 males and 8 females of C. cobaya with body weight ranged 400-450 g. Mating ratio applied was 1:1. Treatments given were 0, 10, 50 and 90 mg of A. cordifolia leaf extract/head, designated as T0, T1, T2 and T3, respectively. Two females were subjected for each treatment. A. cordifolia leaf extract was administered orally from 10 days prepartum to 10 days postpartum...
April 2017: Veterinary World
https://www.readbyqxmd.com/read/28503946/fractional-co2-laser-therapy-a-new-challenge-for-vulvovaginal-atrophy-in-postmenopausal-women
#16
G P Siliquini, V Tuninetti, V E Bounous, F Bert, N Biglia
OBJECTIVE: To evaluate the effects of CO2 laser in the treatment of vulvovaginal atrophy (VVA) in postmenopausal women. METHODS: VVA was assessed in 87 postmenopausal women (mean age 58.6 ± 6.9 years) before and after the treatment. The protocol consisted of three monthly treatments and included the treatment of vulva. Subjective measures included VAS (Visual Analog Scale) both for vaginal dryness and dyspareunia; DIVA (Day-by-day Impact of Vaginal Aging); a questionnaire on treatment satisfaction and one about the degree of pain during the procedure...
May 15, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28503642/vulvar-and-vaginal-graft-versus-host-disease-a-healthcare-clinic-initiative
#17
Naomi Van Dam, Revital Zelker, Ruth Radiano, Ilana Kadmon, Bella Bogorochin, Yevgeni Frank-Kamenetsky
OBJECTIVE: In patients receiving bone marrow transplantation (BMT), their mucosa becomes altered and sclerotic changes in the female external genital organs occur. Although a few studies have specifically addressed vulvar and vaginal graft versus host disease (VVGvHD) and its repercussions on the sexual health and quality of life of patients, VVGvHD can be overlooked by health practitioners. The objective of the study is to describe the initiation of a health care clinic specializing in VVGvHD in a general tertiary hospital...
April 2017: Asia-Pacific Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28503335/primary-villoglandular-mucinous-adenocarcinoma-of-the-vulva
#18
Akiko Matsuzaki, Masanao Saio, Noritake Kosuge, Hajime Aoyama, Tomoko Tamaki, Hirofumi Matsumoto, Naoki Yoshimi
Primary villoglandular mucinous adenocarcinoma of the vulva is rare tumor. We report a case of 68-year-old woman who developed this very uncommon malignant tumor. Immunohistochemical examination of this tumor revealed positive staining for Cytokeratin 20, Mucin 2, and CDX2, although Cytokeratin 7 and Mucin 6 were negative. This positive staining indicated the tumor enteric type characters. In order to exclude the possibility of the metastasis from another site, we thoroughly evaluated clinical data and extensively investigated the whole body...
2017: Case Reports in Pathology
https://www.readbyqxmd.com/read/28502834/a-rare-case-of-intravesical-angiomyofibroblastoma
#19
Phanindra Mohan Deka, Jaynil A Bagawade, Pallavi Deka, Ronica Baruah, Naushad Shah
OBJECTIVES: To study the first reported case of intravesical Angiomyofibroblastoma (AMFB). AMFB is an uncommon benign mesenchymal lesion, mostly described in the lower female genital tract, especially in the vulva and less commonly the vagina. It is rarely seen in the male genital tract. The importance of this rare neoplasm is related to its potential mimicry of more infiltrative and prognostically less favorable lesions, such as aggressive angiomyxomas, that are found in the same anatomic area...
May 11, 2017: Urology
https://www.readbyqxmd.com/read/28491147/a-clinical-guide-to-the-management-of-genitourinary-symptoms-in-breast-cancer-survivors-on-endocrine-therapy
#20
REVIEW
Mariana S Sousa, Michelle Peate, Sherin Jarvis, Martha Hickey, Michael Friedlander
There is increasing attention and concern about managing the adverse effects of adjuvant endocrine therapy for women with early breast cancer as the side effects of therapy influence compliance and can impair quality of life (QoL). Most side effects associated with tamoxifen (TAM) and aromatase inhibitors (AIs) are directly related to estrogen deprivation, and the symptoms are similar to those experienced during natural menopause but appear to be more severe than that seen in the general population. Prolonged estrogen deprivation may lead to atrophy of the vulva, vagina, lower urinary tract and supporting pelvic structures, resulting in a range of genitourinary symptoms that can in turn lead to pain, discomfort, impairment of sexual function and negatively impact on multiple domains of QoL...
April 2017: Therapeutic Advances in Medical Oncology
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