Cyril Dargazanli, Marine Blaquière, Marinette Moynier, Frédéric de Bock, Julien Labreuche, Adrien Ter Schiphorst, Imad Derraz, Răzvan Alexandru Radu, Gregory Gascou, Pierre Henri Lefevre, Francesca Rapido, Julien Fendeleur, Caroline Arquizan, Romain Bourcier, Philippe Marin, Paolo Machi, Federico Cagnazzo, Christophe Hirtz, Vincent Costalat, Nicola Marchi
BACKGROUND: Performing endovascular treatment (EVT) in patients with acute ischemic stroke (AIS) allows a port of entry for intracranial biological sampling. OBJECTIVE: To test the hypothesis that specific immune players are molecular contributors to disease, outcome biomarkers, and potential targets for modifying AIS. METHODS: We examined 75 subjects presenting with large vessel occlusion of the anterior circulation and undergoing EVT. Intracranial blood samples were obtained by microcatheter aspiration, as positioned for stent deployment...
March 21, 2024: Journal of Neurointerventional Surgery