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https://www.readbyqxmd.com/read/28320115/reversible-cerebral-vasoconstriction-syndrome-in-puerperium-a-prospective-study
#1
Gian Paolo Anzola, Renato Brighenti, Milena Cobelli, Alessia Giossi, Sara Mazzucco, Silvia Olivato, Elisa Pari, Maria Paola Piras, Alessandro Padovani, Fabrizio Rinaldi, Giulia Turri
BACKGROUND AND AIM OF THE STUDY: Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by severe "thunderclap" headache, with or without associated neurological symptoms and neuroimaging findings of reversible vasoconstriction of cerebral arteries. Puerperium is a recognized precipitant, but the incidence of puerperal RCVS is unknown. We conducted a prospective study to assess incidence, risk factors and clinical features of RCVS. MATERIAL AND METHOD: Nine-hundred consecutive puerperae were prospectively enrolled within three days of delivery...
April 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28320082/rosmarinic-acid-plays-a-protective-role-in-the-embryogenesis-of-zebrafish-exposed-to-food-colours-through-its-influence-on-aurora-kinase-a-level
#2
Y Swarnalatha, I S Jerrine Joseph, Tippabathani Jayakrishna
OBJECTIVE: To evaluate the protective nature of the rosmarinic acid from Sphaeranthus amaranthoides during zebra fish embryogenesis. METHODS: Rosmarinic acid was isolated from the S. amaranthoides. An accurate, sensitive and simple LC-MS analysis was performed to determine the rosmarinic acid from S. amaranthoides. In the present study, zebrafish embryos were exposed to crimson red and sunset yellow at a concentration of 0.1 and 0.5mg/l and the effect of these food colours on the levels of aurora kinase A was studied individually...
March 14, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28319670/identification-of-candidate-genes-for-the-seed-coat-colour-change-in-a-brachypodium-distachyon-mutant-induced-by-gamma-radiation-using-whole-genome-re-sequencing
#3
Man Bo Lee, Dae Yeon Kim, Yong Weon Seo
Brachypodium distachyon has been proposed as a model plant for agriculturally important cereal crops such as wheat and barley. Seed coat colour change from brown-red to yellow was observed in a mutant line (142-3) of B. distachyon, which was induced by chronic gamma radiation. In addition, dwarf phenotypes were observed in each of the lines 142-3, 421-2, and 1376-1. In order to identify causal mutations for the seed coat colour change, the three mutant lines and the wild type were subjected to whole-genome re-sequencing...
March 20, 2017: Genome Génome / Conseil National de Recherches Canada
https://www.readbyqxmd.com/read/28319275/mrf-ann-a-machine-learning-approach-for-automated-er-scoring-of-breast-cancer-immunohistochemical-images
#4
T Mungle, S Tewary, D K DAS, I Arun, B Basak, S Agarwal, R Ahmed, S Chatterjee, C Chakraborty
Molecular pathology, especially immunohistochemistry, plays an important role in evaluating hormone receptor status along with diagnosis of breast cancer. Time-consumption and inter-/intraobserver variability are major hindrances for evaluating the receptor score. In view of this, the paper proposes an automated Allred Scoring methodology for estrogen receptor (ER). White balancing is used to normalize the colour image taking into consideration colour variation during staining in different labs. Markov random field model with expectation-maximization optimization is employed to segment the ER cells...
March 20, 2017: Journal of Microscopy
https://www.readbyqxmd.com/read/28317945/identification-and-comparative-profiling-of-mirnas-in-herbaceous-peony-paeonia-lactiflora-pall-with-red-yellow-bicoloured-flowers
#5
Daqiu Zhao, Mengran Wei, Min Shi, Zhaojun Hao, Jun Tao
Herbaceous peony (Paeonia lactiflora Pall.) is popular worldwide because of its gorgeous flower colour, and the yellow flower is the rarest. However, its mechanism of yellow formation is still unexplored from the post-translational level. In this study, the anatomy of the petal, cell sap pH and metal elements were investigated in bicoloured flower cultivar 'Jinhui' with red outer-petal and yellow inner-petal, and the yellow formation was influenced by the anatomy of petal, while not by the cell sap pH and metal elements...
March 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28317930/achromatic-light-patterning-and-improved-image-reconstruction-for-parallelized-resolft-nanoscopy
#6
Andriy Chmyrov, Marcel Leutenegger, Tim Grotjohann, Andreas Schönle, Jan Keller-Findeisen, Lars Kastrup, Stefan Jakobs, Gerald Donnert, Steffen J Sahl, Stefan W Hell
Fluorescence microscopy is rapidly turning into nanoscopy. Among the various nanoscopy methods, the STED/RESOLFT super-resolution family has recently been expanded to image even large fields of view within a few seconds. This advance relies on using light patterns featuring substantial arrays of intensity minima for discerning features by switching their fluorophores between 'on' and 'off' states of fluorescence. Here we show that splitting the light with a grating and recombining it in the focal plane of the objective lens renders arrays of minima with wavelength-independent periodicity...
March 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28317858/near-infrared-photoluminescent-carbon-nanotubes-for-imaging-of-brown-fat
#7
Masako Yudasaka, Yohei Yomogida, Minfang Zhang, Takeshi Tanaka, Masako Nakahara, Norihiko Kobayashi, Yuko Okamatsu-Ogura, Ken Machida, Kazuhiko Ishihara, Kumiko Saeki, Hiromichi Kataura
Near-infrared photoluminescent single-walled carbon nanotubes (CNTs) are expected to provide effectual bio-imaging tools, although, as yet, only limited applications have been reported. Here, we report that CNTs coated with an amphiphilic and biocompatible polymer, poly(2-methacryloyloxyethyl phosphorylcholine-co-n-butyl methacrylate; PMB), generate high-quality images of brown fat. Brown fat is a heat-productive adipose tissue, which is attracting increasing attention as a new therapeutic target for obesity-associated metabolic disorders...
March 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28317778/physicochemical-and-sensory-aroma-and-colour-characterisation-of-a-non-centrifugal-cane-sugar-panela-beverage
#8
Juliana María García, Paulo César Narváez, Francisco José Heredia, Álvaro Orjuela, Coralia Osorio
Non-centrifugal cane sugar (NCS), also called "panela", is a high carbohydrate-content food obtained by boil evaporation of the sugar cane juice. This study was undertaken to assess physicochemical properties and sensory characteristics of panela beverage at two different concentrations. Evaluation of pH, °Brix, and colour (tristimulus colorimetry) was carried out in all panela drink samples. In order to characterise the odour-active volatiles of the beverage, a simultaneous steam distillation-solvent extraction method was applied using a mixture of diethyl ether-pentane (1:1,w/w) as solvent...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28317773/comprehensive-chlorophyll-composition-in-the-main-edible-seaweeds
#9
Kewei Chen, José Julián Ríos, Antonio Pérez-Gálvez, María Roca
Natural chlorophylls present in seaweeds have been studied regarding their biological activities and health benefit effects. However, detailed studies regarding characterization of the complete chlorophyll profile either qualitatively and quantitatively are scarce. This work deals with the comprehensive spectrometric study of the chlorophyll derivatives present in the five main coloured edible seaweeds. The novel complete MS(2) characterization of five chlorophyll derivatives: chlorophyll c2, chlorophyll c1, purpurin-18 a, pheophytin d and phytyl-purpurin-18 a has allowed to obtain fragmentation patterns associated with their different structural features...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28317759/the-effects-of-gallic-ferulic-caffeic-acids-on-colour-intensification-and-anthocyanin-stability
#10
Bing-Jun Qian, Jian-Hua Liu, Shu-Juan Zhao, Jian-Xiong Cai, Pu Jing
The mechanism by which copigments stabilize colour, by protecting anthocyanin chromophores from nucleophilic attack, seems well accepted. This study was to determine effects of gallic/ferulic/caffeic acids on colour intensification and anthocyanin stability. Molecular dynamics simulations were applied to explore molecular interactions. Phenolic acids intensified the colour by 19%∼27%. Colour fading during heating followed first-order reactions with half-lives of 3.66, 9.64, 3.50, and 3.39h, whereas anthocyanin degradation, determined by the pH differential method (or HPLC-PDA), followed second-order reactions with half-lives of 3...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28317739/physicochemical-changes-of-phulae-pineapple-fruit-treated-with-short-term-anoxia-during-ambient-storage
#11
Chairat Techavuthiporn, Panida Boonyaritthongchai, Suriyan Supabvanich
The effects of short-term anoxia exposure for 16h on physicochemical changes of 'Phulae' pineapple fruit stored at ambient temperature (25±2°C) were investigated. The respiratory rate of the fruit was induced by the anoxia treatment. However, it retarded the increase in moisture loss and maintained both flesh and pulp colour by inhibiting polyphenol oxidase (PPO) activity of the both tissues. The anoxia exposure delayed the increase in total sugar content and enhanced total ascorbic acid content during storage...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28317722/susceptibility-of-dry-cured-tuna-to-oxidative-deterioration-and-biogenic-amines-generation-i-effect-of-nacl-content-antioxidant-type-and-ageing
#12
L C Roseiro, C Santos, H Gonçalves, C Serrano, C Aleixo, A Partidário, A R Lourenço, M Abreu Dias, D J B da Ponte
This study aimed to assess lipid oxidation and biogenic amine (BA) development in "muxama", a dry-cured tuna muscle product, as affected by salt content, antioxidant type and ageing time. Overall, BA contents decreased with NaCl level (2785.1mgkg(-1), 1148.1mgkg(-1) and 307.7mgkg(-1)) and increased with ageing time (366.2mgkg(-1), 1711.8mgkg(-1) and 2959.2mgkg(-1) in the final product (T0), and after 1 (T1) and 3 (T3) months of ageing, respectively). Regardless of the test conditions, the most concentrated BA was always tyramine...
August 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28316895/interacting-effects-of-early-dietary-conditions-and-reproductive-effort-on-the-oxidative-costs-of-reproduction
#13
Jose Carlos Noguera
The hypothesis that oxidative damage accumulation can mediate the trade-off between reproduction and lifespan has recently been questioned. However, in captive conditions, studies reporting no evidence in support of this hypothesis have usually provided easy access to food which may have mitigated the cost of reproduction. Here, I test the hypothesis that greater investment in reproduction should lead to oxidative damage accumulation and telomere loss in domestic zebra finches Taeniopygia guttata. Moreover, since the change or fluctuation in diet composition between early and late postnatal period can impair the ability to produce antioxidant defences in zebra finches, I also tested if early nutritional conditions (constant vs fluctuating early diet) influenced the magnitude of any subsequent costs of reproduction (e...
2017: PeerJ
https://www.readbyqxmd.com/read/28316136/is-floral-morphology-a-good-predictor-of-floral-visitors-to-antirrhineae-snapdragons-and-relatives
#14
Beatriz Guzmán, José María Gómez, Pablo Vargas
The association between plants and flower visitors has been historically proposed as a main factor driving the evolutionary change of both flower and pollinator phenotypes. The considerable diversity in floral morphology within the tribe Antirrhineae has been traditionally related to pollinator types. We used empirical data on the flower visitors from 59 Antirrhineae taxa from the literature and our own field surveys, which provide an opportunity to test whether flower phenotypes are reliable predictors of visitors and pollinator niches (i...
March 17, 2017: Plant Biology
https://www.readbyqxmd.com/read/28315989/rnai-inhibition-of-feruloyl-coa-6-hydroxylase-reduces-scopoletin-biosynthesis-and-post-harvest-physiological-deterioration-in-cassava-manihot-esculenta-crantz-storage-roots
#15
Shi Liu, Ima M Zainuddin, Herve Vanderschuren, James Doughty, John R Beeching
Cassava (Manihot esculenta Crantz) is a major world crop, whose storage roots provide food for over 800 million throughout the humid tropics. Despite many advantages as a crop, the development of cassava is seriously constrained by the rapid post-harvest physiological deterioration (PPD) of its roots that occurs within 24-72 h of harvest, rendering the roots unpalatable and unmarketable. PPD limits cassava's marketing possibilities in countries that are undergoing increased development and urbanisation due to growing distances between farms and consumers...
March 18, 2017: Plant Molecular Biology
https://www.readbyqxmd.com/read/28315849/environmental-and-genetic-determinants-of-two-vitamin-d-metabolites-in-healthy-australian-children
#16
Abdulhadi Bima, Angela Pezic, Cong Sun, Fergus J Cameron, Christine Rodda, Ingrid van der Mei, Rachel Chiaroni-Clarke, Terence Dwyer, Andrew Kemp, Jun Qu, John Carlin, Justine A Ellis, Anne-Louise Ponsonby
BACKGROUND: Vitamin D deficiency has been associated with adverse health outcomes. We examined genetic and environmental determinants of serum 25(OH)D3 and 1,25(OH)2D3 in childhood. METHODS: The study sample consisted of 322 healthy Australian children (predominantly Caucasians) who provided a venous blood sample. A parental interview was conducted and skin phototype and anthropometry measures were assessed. Concentrations of 25(OH)D3 and 1,25(OH)2D3 were measured by selective solid-phase extraction-capillary liquid chromatography-tandem mass spectrometry...
March 20, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28315656/expression-of-odc1-spd-spm-and-azin1-in-the-hypothalamus-ovary-and-uterus-during-rat-estrous-cycle
#17
Joseph R D Fernandes, Sammit Jain, Arnab Banerjee
The aim of the present study was to investigate variation in the expression pattern of ornithine decarboxylase (ODC1), spermine (SPM), spermidine (SPD) and antizyme inhibitor (AZIN1) in hypothalamus, ovary and uterus during the estrous cycle of rats. Further, to understand any correlation between polyamines and GnRH I expression in hypothalamus; effect of putrescine treatment on GnRH I expression in hypothalamus and progesterone and estradiol levels in serum were investigated. The study also aims in quantifying all the immunohistochemistry images obtained based on pixel counting algorithm to yield the relative pixel count...
March 15, 2017: General and Comparative Endocrinology
https://www.readbyqxmd.com/read/28315400/multicolor-flow-cytometry-and-multi-gene-next-generation-sequencing-are-complementary-and-highly-predictive-for-relapse-in-acute-myeloid-leukemia-following-allogeneic-transplant
#18
Bartlomiej M Getta, Sean M Devlin, Ross L Levine, Maria E Arcila, Abhinita S Mohanty, Ahmet Zehir, Martin S Tallman, Sergio A Giralt, Mikhail Roshal
Minimal Residual disease (MRD) in acute myeloid leukemia (AML) is typically measured using multi-parameter flow cytometry (MFC). Detection of leukemia mutations using multi-gene next generation sequencing (NGS) can potentially be used to measure residual disease. We used a targeted 28-gene NGS panel to detect mutations and different-from-normal 10-colour MFC to measure MRD in AML patients before allogeneic hematopoietic stem cell transplant (HCT). Residual disease was defined when any abnormal blast population was detected using MFC and when any leukemia allele was detected with a variant allele frequency (VAF) ≥5% using NGS...
March 14, 2017: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/28315347/foveal-motion-standstill
#19
Derek H Arnold, Kirstie Petrie, Alan Johnston
Visual analyses of movement are disproportionately reliant on luminance contrast, as opposed to colour differences. One consequence is that if a moving pattern is defined solely by changes in colour (is equiluminant), people can report having no sensation of movement, despite still being able to 'see' the pattern. This is called motion standstill. To date there have been no formal reports of foveal motion standstill. Here we investigate whether this is because the conditions necessary for inducing motion standstill are particular to peripheral vision and therefore absent at the fovea...
March 14, 2017: Vision Research
https://www.readbyqxmd.com/read/28306721/developing-photoreceptor-based-models-of-visual-attraction-in-riverine-tsetse-for-use-in-the-engineering-of-more-attractive-polyester-fabrics-for-control-devices
#20
Roger D Santer
Riverine tsetse transmit the parasites that cause the most prevalent form of human African trypanosomiasis, Gambian HAT. In response to the imperative for cheap and efficient tsetse control, insecticide-treated 'tiny targets' have been developed through refinement of tsetse attractants based on blue fabric panels. However, modern blue polyesters used for this purpose attract many less tsetse than traditional phthalogen blue cottons. Therefore, colour engineering polyesters for improved attractiveness has great potential for tiny target development...
March 17, 2017: PLoS Neglected Tropical Diseases
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