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JOURNAL ARTICLE
Rickesh B Karsan, Katie E O'Sullivan, Christopher J Lockhart, Christopher Austin
BACKGROUND: Infective endocarditis of the aortic valve can result in a wide range of destructive pathology beyond the valve leaflets and annulus which require careful surgical planning to provide appropriate debridement and reconstruction. Failure to do so can result in a failure of surgical treatment, recurrent infection and cardiac failure with concomitant high morbidity and mortality. CASE REPORT: We describe the case of a 45-year-old male with previous patch repair of a ventricular septal defect, who was diagnosed with sub-acute bacterial endocarditis of the native aortic valve and developed a new fistula from the aorta to the right ventricular outflow tract which...
April 16, 2024: Journal of Cardiothoracic Surgery
#2
JOURNAL ARTICLE
Osman Baspinar, Pelin Kosger, Derya Aydin Sahin
The experience with percutaneous closure of postoperative residual ventricular septal defects (VSDs) is expanding with improved device technology and techniques. To report our experience with percutaneous closure of residual VSDs after cardiac surgeries. Retrospective clinical data review of patients who had percutaneous closure of postoperative residual VSDs at our institution between 2010 and 2022. Patients' demographics, procedural, and follow-up data were looked at. Twelve patients (50% males) with a median age of 9...
February 2024: Pediatric Cardiology
#3
JOURNAL ARTICLE
Raymond N Haddad, Zakhia Saliba
We report on a 6-month-old infant (6 Kg/ 64 cm) with perimembranous ventricular septal defect (absent sub-aortic rim, 10 mm left ventricular entry, and 4 and 6 mm right ventricular exists) and successful retrograde closure using an 8x6 mm KONAR-MF™ VSD occluder (Lifetech, China). Immediate and 48 hours post-procedure ultrasounds showed an accurately positioned device and two jets of mild-to-moderate residual shunts. At the 2-week follow-up, the device did not change position and the shunt was stable and intra-prosthetic...
February 2024: Cardiology in the Young
#4
JOURNAL ARTICLE
Yi Xia, Liang Chen, JinWen Lu, Jianhong Ma, Yuanzhen Zhang
BACKGROUND: Congenital heart defect (CHD) is the most common congenital abnormality, and it has long been a clinical and public health concern. Our previous findings have found Periostin (POSTN) and Pappalysin-1 (PAPPA) as potential biomarkers for fetal CHD. We aim to further elucidate POSTN's role in fetal heart development and explore the clinical applicability of POSTN and PAPPA as diagnostic marker for fetal CHD. This study is poised to establish a theoretical framework for mitigating the incidence of CHD and advance a novel approach for prenatal screening of fetal CHD...
December 11, 2023: Journal of Translational Medicine
#5
JOURNAL ARTICLE
Yan Yang, Linyun Xi, Hongbo Li
To assess the safety and effectiveness of utilizing eccentric occlusion for the treatment of sub-arterial ventricular septal defects, we performed a retrospective study on the classification and analysis of relevant cases. A total of 105 patients with a minimally invasive incision were enrolled in this study, from April 2018 to September 2022. All patients underwent treatment of transthoracic sub-arterial ventricular septal defect occlusion. We analyzed the causes of closure failure, indication, and complication...
October 6, 2023: Pediatric Cardiology
#6
Miguel Ángel Serrano-Sánchez, Alfredo Sotomayor-Estrada, W Samir Cubas
Aneurysm of the Sinus of Valsalva (ASV) is a rare abnormality and affects less than 0.1% of the general population. We describe the case of a 37-year-old woman with a clinical picture characterized by dyspnea, palpitations, and syncope of 6 years of evolution. The echocardiographic study revealed a right ASV with a sub pulmonary interventricular perforation of 8mm and producing a regurgitant jet into the right ventricle, causing dilatation of the right ventricular outflow tract, pulmonary artery, and severe aortic insufficiency Carpentier DI...
2023: Arch Peru Cardiol Cir Cardiovasc
#7
JOURNAL ARTICLE
Raymond N Haddad, Zakhia S Saliba
BACKGROUND: Retrograde closure of perimembranous ventricular septal defects (pmVSDs) is a well-established procedure. However, interventionists are still looking for the best closure device. METHODS: We performed a single-center retrospective review of 5-year-experience (from July 2015 to July 2020) with retrograde closure of pmVSDs using AmplatzerTM Duct Occluder II (ADOII) and KONAR-MF™ VSD occluder (MFO). Deficient sub-aortic rim (SAR) (≤2.5 mm for MFO and ≤3 mm for ADOII) was an exclusion criterion in defects with a diameter ratio (right-side exit/left-side entry) > 0...
2023: Frontiers in Cardiovascular Medicine
#8
JOURNAL ARTICLE
B M Jepson, T D Metz, T A Miller, S L Son, Z Ou, A P Presson, A Nance, N M Pinto
OBJECTIVE: Fetuses with congenital heart disease (CHD) are at increased risk of pregnancy loss compared with the general population. We aimed to assess the incidence, timing and risk factors of pregnancy loss in cases with major fetal CHD, overall and according to cardiac diagnosis. METHODS: This was a retrospective, population-level cohort study of fetuses and infants diagnosed with major CHD between 1997 and 2018 identified by the Utah Birth Defect Network (UBDN), excluding cases with termination of pregnancy and minor cardiovascular diagnoses (e...
July 2023: Ultrasound in Obstetrics & Gynecology
#9
JOURNAL ARTICLE
Lambert Tetteh Appiah, Solomon Gyabaah, Yaw Adu-Boakye, Bernard C Nkum
BACKGROUND: Sub-valvular aortic stenosis is a rare disorder that has a prevalence of 6.5% of all adult congenital heart diseases. The hemodynamic changes that occur in pregnancy with the resultant increase in cardiac output may not well be tolerated by a pregnant woman with sub-valvular aortic stenosis. CASE PRESENTATION: We report the case of a 34-year-old para 7 (6 alive + 1 dead) who has been experiencing intermittent episodes of easy fatigability on moderate exertion since childhood and had survived 6 prior pregnancies...
April 18, 2023: BMC Cardiovascular Disorders
#10
JOURNAL ARTICLE
Kaijun Zhang, Penghui Yang, Dan Yin, Mi Li, Xiaohua Liang, Tiewei Lv, Min Zheng, Ping Xiang
INTRODUCTION: Our aim is to investigate the incidence and risk factors for aortic regurgitation (AR) requiring unplanned surgery after transcatheter closure of ventricular septal defect (VSD) in children. METHODS: Medical records of 876 children with VSD who underwent transcatheter closure from July 2009 to September 2018 in our hospital were retrospectively reviewed. Groups with and without new-onset or increasing AR requiring unplanned surgery were compared. Univariate and multivariate analysis were used to identify the possible risk factors...
November 22, 2022: Cardiology
#11
JOURNAL ARTICLE
Rajesh Sharma, Anil Bhan, Arushi Nautiyal, Aliza Mittal, Romel Akole, Neha Malhotra, Firdoos Ahmad Mir, Pankaj Bajpai, Amit Misri, Swarnika Srivastava, Ved Prakash, Abhishek Tibrewal, Pranaw Kumar Jha, Shyam Bihari Bansal, Vijay Kher, Rupesh Raina, Sidharth Kumar Sethi
Acute kidney injury (AKI) in children with Transposition of Great arteries (TGA) undergoing Arterial Switch operation (ASO) is an important complication in the post-operative period associated with worse outcomes. AKI in children post open cardiac surgery has been well studied, with lesser data in literature pertaining to TGA and its sub-types specifically. This was a prospective, observational study enrolling infants with TGA undergoing ASO at a single center over a span of a decade from January 2010 to December 2020...
May 15, 2022: Pediatric Cardiology
#12
JOURNAL ARTICLE
F A Ujunwa, J M Chinawa, V Okwulehie, E K Obidike
Background: Structural heart disease is a major cause of morbidity and mortality in children. Echocardiography is accepted as the first line cost-effective diagnostic modality for pre-operative assessment of children with structural heart diseases. Two-dimensional transthoracic echocardiography (2-D TTE) may be the only diagnostic tool in a resource-poor environment where further investigations may be very expensive and not readily available. Aim: The aim of the study is to determine the degree of accuracy of pre-operative 2-D echocardiographic diagnosis with eventual surgical (intra-operative) findings among children with structural heart diseases with a view to audit the echocardiographic diagnoses and final surgical diagnoses among the patients in the University of Nigeria Teaching Hospital Ituku-Ozalla Enugu, a tertiary cardiothoracic center in Enugu, South-east Nigeria...
April 2022: Nigerian Journal of Clinical Practice
#13
JOURNAL ARTICLE
Arash Gharehbaghi, Ankica Babic
This paper presents an original method for studying the performance of the supervised Machine Learning (ML) methods, the A-Test method. The method offers the possibility of investigating the structural risk as well as the learning capacity of ML methods in a quantitating manner. A-Test provides a powerful validation method for the learning methods with small or medium size of the learning data, where overfitting is regarded as a common problem of learning. Such a condition can occur in many applications of bioinformatics and biomedical engineering in which access to a large dataset is a challengeable task...
January 14, 2022: Studies in Health Technology and Informatics
#14
Pezad Doctor, Jennifer Blake, Sanjeev Aggarwal
Double outlet left ventricle (DOLV) is a rare congenital heart defect where the aorta and the pulmonary trunk arise predominantly from the morphologic left ventricle. The clinical manifestations depend upon the location of the ventricular septal defect in relation to the great arteries, degree of pulmonary and aortic outflow tract obstruction, and other associated cardiac defects. We describe a neonate with DOLV, sub-aortic ventricular septal defect, and side-by-side great vessels who continued to require oxygen for desaturation to 60% in the neonatal period...
January 2022: Journal of Cardiology Cases
#15
REVIEW
Lisa Guirgis, Estibaliz Valdeolmillos, Guy Vaksmann, Clément Karsenty, Ali Houeijeh, Eric Hery, Pascal Amedro, Nicolas Pangaud, Nadir Benbrik, Carine Vastel, Antoine Legendre, Zakaria Jalal, Khaled Hadeed, Magalie Ladouceur, Laurence Iserin, Daniela Laux, Xavier Iriart, Karine Warin Fresse, Bertrand Leobon, Samir Harchaoui, Virginie Lambert, Ronan Bonefoy, Adeline Basquin, Aurélie Chalard, Stéphanie Douchin, Ivan Bouzguenda, Charlotte Denis, Hugues Lucron, Gilles Bosser, Elise Barre, Bérangère Urbina-Hiel, Pauline Helms, Hélène Ansquer, Quentin Hauet, Anne-Sophie Leborgne, Laurence Cohen, Jean Marc Lupoglazoff, Maurice Guirgis, Céline Gronier, Pascale Maragnes, Pamela Moceri, Pierre Mauran, Claire Bertail, Bruno Lefort, François Godart, Alban-Elouen Baruteau, Caroline Ovaert, Damien Bonnet, Nicolas Combes, Diala Khraiche, Lucile Houyel, Jean Benoit Thambo, Meriem Mostefa-Kara, Sébastien Hascoet
UNLABELLED: The long-term prospective multi-centre nationwide (French) observational study FRANCISCO will provide new information on perimembranous ventricular septal defect with left ventricular overload but no pulmonary hypertension in children older than 1 year. Outcomes will be compared according to treatment strategy (watchful waiting, surgical closure, or percutaneous closure) and anatomic features of the defect. The results are expected to provide additional guidance about the optimal treatment of this specific population, which is unclear at present...
October 2021: Cardiology in the Young
#16
JOURNAL ARTICLE
Balaji Arvind, Sivasubramanian Ramakrishnan, Velayoudam Devagourou
Double chambered right ventricle is a rare cardiac defect characterised by an obstructive hypertrophied muscle bundle in the right ventricle. The common associated lesions are ventricular septal defect followed by sub-aortic membrane. We report a child who had coarctation of aorta in association with double chambered right ventricle. This case is being reported for its rarity and challenges in management.
August 5, 2021: Cardiology in the Young
#17
JOURNAL ARTICLE
M Camilli, P Ciampi, D Pedicino, A D'Aiello, A Mazza, R A Montone, T Sanna, A G Rebuzzi, M Massetti, F Crea, G Liuzzo
OBJECTIVE: Ventricular septal defect (VSD) is an uncommon but frequently fatal complication following acute myocardial infarction. In medically treated patients, mortality rates exceed 90%, while the surgical repair is associated with better outcomes, even though optimal surgical timing is still under debate. CASE REPORT: We present the case of a 78-years-old man with no previous remarkable cardiological history admitted to our Emergency Department with the diagnosis of anterior ST-elevation myocardial infarction and significant reduction of left ventricular ejection fraction...
April 2021: European Review for Medical and Pharmacological Sciences
#18
JOURNAL ARTICLE
Stephany B Lucina, Ana P Sarraff, Marcela Wolf, Vinícius B C Silva, Marlos G Sousa, Tilde R Froes
The aim of the study was to estimate the prevalence of congenital heart diseases in dogs attending 2 veterinary hospitals in Brazil and to identify possible associations between these conditions and epidemiological characteristics. A retrospective study was carried out in the cardiology sections of 2 veterinary hospitals during a period of 70 months from January 2012 and October 2017. Of a total of 6710 dogs that attended the cardiology sections of the hospitals, 109 congenital heart diseases were identified in 95 patients, representing a prevalence of 1...
December 17, 2020: Topics in Companion Animal Medicine
#19
JOURNAL ARTICLE
Ondrej Fabian, Roman Gebauer, Viktor Tomek, Ludmila Hornofova, Mariia Havova, Ondrej Materna, Jan Janousek
OBJECTIVES: We reviewed a spectrum of congenital heart defects assessed in our center between 1/2010 and 4/2020, evaluated their gross anatomy, assessed the age distribution, evaluated performed surgical procedures, and correlated gross and ultrasound findings. METHODS: All necroptic cases and explanted hearts that underwent specialized cardiac autopsy were included in this study. Autopsy findings including gross description of congenital heart defects together with echocardiographic findings were retrospectively assessed...
November 12, 2020: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
#20
JOURNAL ARTICLE
Andrea Ponsiglione, Gianrico Spagnuolo, Gabriella Spagnuolo, Arnaldo Stanzione, Carmela Nappi, Serena Dell'Aversana, Antonio Spagnuolo, Alberto Cuocolo, Massimo Imbriaco
BACKGROUND: The Starr-Edwards ball valve prosthesis was successfully introduced in 1961-62 and largely used for aortic and mitral valve replacement. Even if Starr-Edwards valves have been widely replaced in clinical practice by other mechanical valves, they define a standard concerning long-term durability. CASE PRESENTATION: We describe the case of a 55-year-old man referred to our Department to perform a cardiac computed tomography (CCT), to better evaluate a severe dilation of ascending aorta discovered at echocardiography...
January 29, 2020: BMC Cardiovascular Disorders
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