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Feridoun Sabzi, Reza Faraji
We report an exceptional case of, 33-year-old woman presenting with, dyspnoea and chest pain, Cardio respiratory sign and symptom related to diastolic dysfunction caused by mass effect of thrombosis on diastolic filling of left ventricule (LV). The common aetiologies of these devastating complication results in thrombophillia diagnosis, and echocardioghraphy showed a large mass in left ventricular cavity. In laboratory exam, protein C-S deficiency was confirmed however, others related test of thrombophillia were negative...
July 2014: Nigerian Medical Journal: Journal of the Nigeria Medical Association
Geordan D Shannon, Corinna Alberg, Luis Nacul, Nora Pashayan
Congenital disorders are a leading cause of global burden of disease; the birth prevalence remains constant at 6%. Initiating preconception care before pregnancy may be an effective strategy to reduce congenital disorders and improve the health of reproductive-age women. Our objectives are: (1) To identify components of preconception interventions, (2) to assess the effectiveness of preconception interventions in reducing the burden of congenital disorders, and (3) to prioritize these interventions. Medline and Science Direct search terms included: preconception, pre-pregnancy, childbearing, reproduction, care, intervention, primary care, healthcare, model, program, prevention, trial, efficacy, effectiveness, congenital disorders OR abnormalities...
August 2014: Maternal and Child Health Journal
A P Croft, J N Khan, M V Chittari, C Varma
Paradoxical coronary artery embolism is a rare but under-diagnosed cause of acute myocardial infarction (AMI) and requires a high level of clinical suspicion to make an early diagnosis. We describe the case of a young woman who presented with a severe cough and chest pain who was subsequently found to have a paradoxical embolus in the right coronary artery. Echocardiography showed a patent foramen ovale (PFO) and an atrial septal aneurysm (ASA). The patient was found to be a heterozygous carrier of the factor V Leiden mutation that increases the risk for venous-thromboembolism...
2012: Journal of the Royal College of Physicians of Edinburgh
Shilpa Tulankar, Yojana Gokhale, Satish Dharap, S Prabhakar
AIM: To find out the proportion of non-diabetic peripheral arterial disease (PAD) attributable to systemic connective tissue diseases (CTD) or thrombophillic states as etiology and to identify clinical and laboratory features that would point towards systemic disease other than atherosclerosis. MATERIALS AND METHODS: We studied the etiology of PAD in 45 non-diabetic patients in a tertiary health care center in Mumbai prospectively from January 2004- December '07...
April 2011: Journal of the Association of Physicians of India
M Koucký, A Germanová, Z Hájek, A Parízek, M Kalousová, P Kopecký
OBJECTIVE: To summarize available data concerning pathophysiology and management of preterm labour and their use in clinical practice. SETTING: Department of Obstetrics and Gynecology od the First Faculty of Medicine, Charles University, and General Teaching Hospital, Prague. DESIGN: Review article. METHODS: Compilation od published data from scientific literature. CONCLUSION: Birth canal infections seem to play a key role in the ethiopathogenesis of premature delivery; the related biochemical changes significantly affect perinatal morbidity and mortality...
February 2009: Ceská Gynekologie
Sonali Birewar, Melvin Thomas, Michael S McHale
We report a case of a 33-year old male admitted to our hospital with extensive lower extremity deep venous thrombosis (DVT). This patient was several days post knee arthroscopy and had a family history strongly positive for DVT. Upon testing, he was found positive for the homozygous presence of Factor V gene R506Q mutation. In inherited thrombophillia, especially in homozygous Factor V Leiden, lifelong anticoagulation treatment and screening for asymptomatic family members is controversial. Upon review and consultation, however, we recommended oral anticoagulation for life, along with genetic counseling and screening for Factor V Leiden of his three children and younger brother...
June 2003: South Dakota Journal of Medicine
M M Ahmed, D H Akbar, A R Al-Shaikh
OBJECTIVE: To study the incidence of deep vein thrombosis and pulmonary embolism at King Abdul Aziz University Hospital. To determine the risk factors, use of different diagnostic modalities, treatment given and to compare our findings with those reported in the literature. METHODS: Retrospective study which included all cases of deep vein thrombosis and pulmonary embolism admitted to the medical ward of King Abdul Aziz University Hospital during the period between January 1994 till March 1999 were analyzed...
August 2000: Saudi Medical Journal
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