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ventilator associated pneumonia

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https://www.readbyqxmd.com/read/28915393/the-comparative-effectiveness-of-noninvasive-and-invasive-ventilation-in-patients-with-pneumonia
#1
Mihaela S Stefan, Aruna Priya, Penelope S Pekow, Tara Lagu, Jay S Steingrub, Nicholas S Hill, Brian H Nathanson, Peter K Lindenauer
PURPOSE: To compare the outcomes of patients hospitalized with pneumonia treated with noninvasive ventilation (NIV) and invasive mechanical ventilation (IMV). MATERIALS AND METHODS: Using the HealthFacts multihospital electronic medical record database, we included patients hospitalized with a diagnosis of pneumonia and treated with NIV or IMV. We developed a propensity model for receipt of initial NIV and assessed the outcomes in a propensity-matched cohort, and in a covariate adjusted and propensity score weighted models...
May 23, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28915364/nosocomial-multidrug-resistant-klebsiella-pneumoniae-strains-isolated-from-mexico-city-produce-robust-biofilms-on-abiotic-surfaces-but-not-on-human-lung-cells
#2
Martha Lorena Ostria-Hernandez, Karla Cecilia Juárez-de la Rosa, Patricia Arzate-Barbosa, Antonino Lara-Hernández, Fuminori Sakai, J Antonio Ibarra, Graciela Castro-Escarpulli, Jorge E Vidal
BACKGROUND: Klebsiella pneumoniae (Kpn) strains are a leading cause of hospital-acquired infections, including ventilator-associated pneumonia. Resistance to antibiotics, biofilm formation, and the production of certain fimbriae play an important role in the pathogenesis. AIM: We investigated the genetic relatedness, antibiotic resistance, virulence potential, and ability to form biofilms of Kpn strains isolated from hospital-acquired infections (n = 76). Strains were isolated at three major hospitals serving the largest metropolitan urban area in Mexico City, Mexico...
September 15, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28906137/treatment-of-achromobacter-ventilator-associated-pneumonia-in-critically-ill-trauma-patients
#3
G Christopher Wood, Brittany L Jonap, George O Maish, Louis J Magnotti, Joseph M Swanson, Bradley A Boucher, Martin A Croce, Timothy C Fabian
BACKGROUND: Achromobacter sp are nonfermenting Gram-negative bacilli (NFGNB) that rarely cause severe infections, including ventilator-associated pneumonia (VAP). Data on the treatment of Achromobacter pneumonia are very limited, and the organism has been associated with a high mortality rate. Thus, more data are needed on treating this organism. OBJECTIVE: To evaluate the treatment of Achromobacter VAP in critically ill trauma patients. METHODS: This retrospective, observational study evaluated critically ill trauma patients who developed Achromobacter VAP...
September 1, 2017: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/28905374/heat-and-moisture-exchangers-versus-heated-humidifiers-for-mechanically-ventilated-adults-and-children
#4
REVIEW
Donna Gillies, David A Todd, Jann P Foster, Bisanth T Batuwitage
BACKGROUND: Invasive ventilation is used to assist or replace breathing when a person is unable to breathe adequately on their own. Because the upper airway is bypassed during mechanical ventilation, the respiratory system is no longer able to warm and moisten inhaled gases, potentially causing additional breathing problems in people who already require assisted breathing. To prevent these problems, gases are artificially warmed and humidified. There are two main forms of humidification, heat and moisture exchangers (HME) or heated humidifiers (HH)...
September 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28905112/extracorporeal-membrane-oxygenation-in-spina-bifida-and-h1n1-induced-acute-respiratory-distress-syndrome
#5
Oliver Jansen, Oliver Kamp, Christian Waydhas, Valentin Rausch, Thomas Armin Schildhauer, Justus Strauch, Dirk Buchwald, Uwe Hamsen
Acute respiratory distress syndrome (ARDS) is characterized as an acute hypoxemic and/or hypercapnic respiratory failure seen in critically ill patients and is still, although decreased over the past few years, associated with high mortality. Furthermore, ARDS may be a life-threatening complication of H1N1 pneumonia. We report on a 45-year-old spina bifida patient with confirmed H1N1 influenza virus infection causing acute respiratory failure, who was successfully weaned from 42-day veno-venous extracorporeal membrane oxygenation (vv-ECMO) treatment with an excellent outcome...
September 13, 2017: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/28902529/evaluation-of-the-2016-infectious-diseases-society-of-america-american-thoracic-society-guideline-criteria-for-risk-of-multi-drug-resistant-pathogens-in-hospital-acquired-and-ventilator-associated-pneumonia-patients-in-the-intensive-care-unit
#6
Pervin Korkmaz Ekren, Otavio T Ranzani, Adrian Ceccato, Gianluigi Li Bassi, Eva Muñoz Conejero, Miquel Ferrer, Michael S Niederman, Antoni Torres
No abstract text is available yet for this article.
September 13, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28895575/predictors-of-pressure-ulcer-incidence-following-traumatic-spinal-cord-injury-a-secondary-analysis-of-a-prospective-longitudinal-study
#7
D Brienza, S Krishnan, P Karg, G Sowa, A L Allegretti
STUDY DESIGN: Secondary analysis of data from a prospective cohort study. OBJECTIVES: The objective of this study was to identify the medical and demographic factors associated with the development of pressure ulcers during acute-care hospitalization and inpatient rehabilitation following acute spinal cord injury. SETTING: The study was carried out at acute hospitalization, inpatient rehabilitation and outpatient rehabilitation sites at a university medical center in the United States...
September 12, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28894766/potentially-preventable-hospitalizations-and-the-burden-of-healthcare-associated-infections
#8
Andrea L Lorden, Luohua Jiang, Tiffany A Radcliff, Kathleen A Kelly, Robert L Ohsfeldt
BACKGROUND: An estimated 4% of hospital admissions acquired healthcare-associated infections (HAIs) and accounted for $9.8 (USD) billion in direct cost during 2011. In 2010, nearly 140 000 of the 3.5 million potentially preventable hospitalizations (PPHs) may have acquired an HAI. There is a knowledge gap regarding the co-occurrence of these events. AIMS: To estimate the period occurrences and likelihood of acquiring an HAI for the PPH population. METHODS: Retrospective, cross-sectional study using logistic regression analysis of 2011 Texas Inpatient Discharge Public Use Data File including 2...
January 2017: Health Services Research and Managerial Epidemiology
https://www.readbyqxmd.com/read/28894481/respiratory-research-networks-in-europe-and-beyond-aims-achievements-and-aspirations-for-the-21st-century
#9
Ignacio Martin-Loeches, Fernando Zampieri, Pedro Povoa, Otavio Ranzani, Lieuwe D Bos, Stefano Aliberti, Antoni Torres
Healthcare-associated infection, such as intensive care unit (ICU)-related respiratory infections, remain the most frequently encountered morbidity of ICU admission, prolonging hospital stay and increasing mortality rates. The epidemiology of ICU-related respiratory infections, particularly nonventilated ICU-associated pneumonia and ventilator-associated tracheobronchitis, appears to be quite different among different countries. European countries have different prevalence, patterns and mechanism of resistance, as well as different treatments chosen by different attending physicians...
September 2017: Breathe
https://www.readbyqxmd.com/read/28892891/distribution-of-class-d-carbapenemase-and-extended-spectrum-%C3%AE-lactamase-genes-among-acinetobacter-baumannii-isolated-from-burn-wound-and-ventilator-associated-pneumonia-infections
#10
Maryam Mohammadi, Setareh Soroush, Somayeh Delfani, Iraj Pakzad, Abolfazl Abbaszadeh, Mahmoud Bahmani, Lidija Bogdanovic, Morovat Taherikalani
INTRODUCTION: Resistance to Acinetobacter baumannii is dramatically on the rise in Iran. Therefore, it is important to study resistance pattern among Acinetobacter isolates which is a common cause of nosocomial infections. AIM: To investigate antibiotic resistance patterns and the role of resistant genes and biofilm formation in the induction of resistance among Acinetobacter baumannii isolated from burn wound and ventilator associated pneumonia infections. MATERIALS AND METHODS: Total 103 isolates such as 33 burn samples from Rasool Akram Hospital and 70 isolates from ventilated patients in Shahid Motahhari Hospital were identified with A...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28891372/controversies-and-advances-in-the-management-of-ventilator-associated-pneumonia
#11
Katherine L Roberts, Marin H Kollef, Scott T Micek, Paul Juang
Although national surveillance data suggests that the incidence of ventilator associated pneumonia (VAP) is down-trending, it remains one of the most commonly encountered hospital acquired infections in the United States and worldwide. Its association with increased healthcare costs and worsened patient outcomes warrants continued effort to improve the care of patients with VAP. Areas covered: The increasing prevalence of multi-drug resistant bacteria further drives the need to explore advances in diagnostic and treatment options...
September 11, 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/28891032/the-need-for-unique-risk-adjustment-for-surgical-site-infections-at-a-high-volume-tertiary-care-center-with-inherent-high-risk-colorectal-procedures
#12
E Gorgun, C Benlice, J Hammel, T Hull, L Stocchi
BACKGROUND: The aim of the present study was to create a unique risk adjustment model for surgical site infection (SSI) in patients who underwent colorectal surgery (CRS) at the Cleveland Clinic (CC) with inherent high risk factors by using a nationwide database. METHODS: The American College of Surgeons National Surgical Quality Improvement Program database was queried to identify patients who underwent CRS between 2005 and 2010. Initially, CC cases were identified from all NSQIP data according to case identifier and separated from the other NSQIP centers...
September 11, 2017: Techniques in Coloproctology
https://www.readbyqxmd.com/read/28890434/international-ers-esicm-escmid-alat-guidelines-for-the-management-of-hospital-acquired-pneumonia-and-ventilator-associated-pneumonia-guidelines-for-the-management-of-hospital-acquired-pneumonia-hap-ventilator-associated-pneumonia-vap-of-the-european-respiratory
#13
Antoni Torres, Michael S Niederman, Jean Chastre, Santiago Ewig, Patricia Fernandez-Vandellos, Hakan Hanberger, Marin Kollef, Gianluigi Li Bassi, Carlos M Luna, Ignacio Martin-Loeches, J Artur Paiva, Robert C Read, David Rigau, Jean François Timsit, Tobias Welte, Richard Wunderink
The most recent European guidelines and task force reports on hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP) were published almost 10 years ago. Since then, further randomised clinical trials of HAP and VAP have been conducted and new information has become available. Studies of epidemiology, diagnosis, empiric treatment, response to treatment, new antibiotics or new forms of antibiotic administration and disease prevention have changed old paradigms. In addition, important differences between approaches in Europe and the USA have become apparent...
September 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28890209/nursing-workload-and-adherence-to-non-pharmacological-measures-in-the-prevention-of-ventilator-associated-pneumonia-a-pilot-study
#14
R Jam, O Hernández, J Mesquida, C Turégano, E Carrillo, R Pedragosa, V Gómez, L Martí, J Vallés, P Delgado-Hito
OBJECTIVE: To analyse whether adherence to non-pharmacological measures in the prevention of ventilator-associated pneumonia (VAP) is associated with nursing workload. METHODS: A prospective observational study performed in a single medical-surgical ICU. Nurses in charge of patients under ventilator support were assessed. VARIABLES: knowledge questionnaire, application of non-pharmacological VAP prevention measures, and workload (Nine Equivalents of Nursing Manpower Use Score)...
September 7, 2017: Enfermería Intensiva
https://www.readbyqxmd.com/read/28888319/systems-based-practice-in-burn-care-prevention-management-and-economic-impact-of-health-care-associated-infections
#15
REVIEW
Charles Scott Hultman, David van Duin, Emily Sickbert-Bennett, Lauren M DiBiase, Samuel W Jones, Bruce A Cairns, David J Weber
Health care-associated infections in burn patients, from ventilator-associated pneumonia to skin and soft tissue infections, can substantially compromise outcomes, because these complications are associated with longer lengths of stay, increased morbidity and mortality, and greater direct medical costs. Health care-associated infections are largely preventable, through surveillance, education, appropriate hand hygiene, and culture change, especially for device-related infections. Systems-based practice, which allows individuals and clinical microsystems to navigate and improve the macro health care system, may be one of the most powerful skill sets to effect change, permitting a shift in culture toward patient safety and quality improvement...
October 2017: Clinics in Plastic Surgery
https://www.readbyqxmd.com/read/28886850/transcatheter-aortic-valve-implantation-versus-surgical-aortic-valve-replacement-in-lower-surgical-risk-patients-with-chronic-obstructive-pulmonary-disease
#16
Vincent Auffret, Victor Becerra Munoz, Aurélie Loirat, Eric Dumont, Hervé Le Breton, Jean-Michel Paradis, Daniel Doyle, Robert De Larochellière, Siamak Mohammadi, Jean-Philippe Verhoye, François Dagenais, Marc Bedossa, Dominique Boulmier, Guillaume Leurent, Lluis Asmarats, Ander Regueiro, Chekrallah Chamandi, Tania Rodriguez-Gabella, Emile Voisine, Anne-Sophie Moisan, Martin Thoenes, Mélanie Côté, Rishi Puri, Pierre Voisine, Josep Rodés-Cabau
Respiratory complications are a major factor contributing to postoperative morbidity and mortality, especially in patients with chronic obstructive pulmonary disease (COPD). Our objective was to compare the rate of respiratory complications in patients with COPD with severe aortic stenosis who underwent transcatheter aortic valve implantation (TAVI) versus surgical aortic valve replacement (SAVR). Low-to-intermediate surgical-risk patients with moderate or severe COPD who underwent TAVI or SAVR at 2 tertiary centers were included in this study...
August 7, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28884567/high-peak-pao2-values-are-associated-with-adverse-outcome-in-critically-ill-patients-treated-with-non-invasive-ventilation-for-acute-cardogenic-pulmonary-edema-and-pneumonia
#17
Christiana Schernthaner, Bernhard Wernly, Michael Lichtenauer, Marcus Franz, Alexander Lauten, Paul C Schulze, Bjoern Kabisch, Kristina Braun, Johanna Muessig, Maryna Masyuk, Uta C Hoppe, Malte Kelm, Christian Jung
BACKGROUND: Non-invasive Ventilation (NIV) has a sigificant impact on mortality in acute respiratory failure (ARF). Predictive parameters for mortality are of high interest. METHODS: We retrospectively analyzed 3759 blood gas analysis and clinical parameters of 475 patients presenting with ARF based on acute cardiogenic pulmonary edema and/or pneumonia. The influence of peak arterial oxygen partial pressure levels (PaO2) with respect to its predictive value for in-hopital and long-term mortality was investigated...
September 7, 2017: Panminerva Medica
https://www.readbyqxmd.com/read/28883139/complete-genome-sequences-of-four-extensively-drug-resistant-pseudomonas-aeruginosa-strains-isolated-from-adults-with-ventilator-associated-pneumonia-at-a-tertiary-referral-hospital-in-mexico-city
#18
Luis F Espinosa-Camacho, Gabriela Delgado, Gloria Soberón-Chávez, Luis D Alcaraz, Jorge Castañon, Rosario Morales-Espinosa
Four extensively drug-resistant Pseudomonas aeruginosa strains, isolated from patients with pneumonia, were sequenced using PacBio RS-II single-molecule real-time (SMRT) technology. Genome sequence analysis identified great variability among mobile genetic elements, as well as some previously undescribed genomic islands and new variants of class 1 integrons (In1402, In1403, In1404, and In1408).
September 7, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28880805/a-prospective-one-year-microbiologic-survey-of-combined-pneumonia-and-respiratory-failure
#19
Kristen Fisher, Tracy Trupka, Scott T Micek, Paul Juang, Marin H Kollef
BACKGROUND: Pneumonia and respiratory failure are common problems in the intensive care unit (ICU) setting, often occurring together. The relative prevalence of pneumonia types (community acquired, hospital acquired, ventilator associated) and causative pathogens is not well described in patients with respiratory failure. METHODS: This was a prospective observational cohort study conducted in the medical ICU (34 beds) of Barnes-Jewish Hospital, an academic referral center of 1,300 beds from January 2016-December 2016...
September 7, 2017: Surgical Infections
https://www.readbyqxmd.com/read/28878043/the-rapid-in-vivo-evolution-of-pseudomonas-aeruginosa-in-ventilator-associated-pneumonia-patients-leads-to-attenuated-virulence
#20
Ke Wang, Yi-Qiang Chen, May M Salido, Gurjeet S Kohli, Jin-Liang Kong, Hong-Jie Liang, Zi-Ting Yao, Yan-Tong Xie, Hua-Yu Wu, Shuang-Qi Cai, Daniela I Drautz-Moses, Aaron E Darling, Stephan C Schuster, Liang Yang, Yichen Ding
Pseudomonas aeruginosa is an opportunistic pathogen that causes severe airway infections in humans. These infections are usually difficult to treat and associated with high mortality rates. While colonizing the human airways, P. aeruginosa could accumulate genetic mutations that often lead to its better adaptability to the host environment. Understanding these evolutionary traits may provide important clues for the development of effective therapies to treat P. aeruginosa infections. In this study, 25 P. aeruginosa isolates were longitudinally sampled from the airways of four ventilator-associated pneumonia (VAP) patients...
September 2017: Open Biology
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