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Neovascular glaucoma

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https://www.readbyqxmd.com/read/29451146/safety-and-efficiency-of-trabectome-mediated-trabecular-meshwork-ablation-for-chinese-glaucoma-patients-a-two-year-retrospective-multicentre-study
#1
Ya-Long Dang, Yu-Jie Cen, Ying Hong, Ping Huang, Ning-Li Wang, Chao Wang, Chun Zhang
Background: The aim of the study was to evaluate the long-term safety and efficacy of the Trabectome for Chinese glaucoma patients. Methods: This was a multicenter, retrospective, observational study. Glaucoma patients, except those with neovascular glaucoma, with/without a visually significant cataract were enrolled. The patients received Trabectome or a combined surgery with phacoemulsification and intraocular lens implantation. The primary outcome evaluation was a reduction in intraocular pressure (IOP), and the secondary outcomes were a reduction in glaucoma medication, the 2-year success percentages, and complications...
February 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29450400/incidence-of-ocular-hypertension-after-intravitreal-injection-of-anti-vegf-agents-in-the-treatment-of-neovascular-amd
#2
Andreea Moraru, Gabriela Pînzaru, Anca Moţoc, Dănuţ Costin, Daniel Brănişteanu
Purpose. The assessment of the incidence of ocular hypertension over a period of 1 year in patients treated with multiple intravitreal injections of anti-VEGF agents for neovascular AMD. Methods. The study comprised 58 eyes diagnosed with neovascular age-related macular degeneration and receiving PRN intravitreal treatment with anti-VEGF agents (bevacizumab or aflibercept). The follow-up period was 1 year. Intraocular pressure was measured by using the Goldmann applanation tonometry before the intravitreal injection, at 24 hours after the administration of the anti-VEGF agent and at 1 and 4 weeks...
July 2017: Romanian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29450382/iridex-micropulse-p3-innovative-cyclophotocoagulation
#3
M Monica Gavris, Ioana Olteanu, Erzsebet Kantor, Radu Mateescu, Roxana Belicioiu
Purpose: To present the new IRIDEX MicroPulse P3 (MP3) technology in patients with refractory glaucoma and our preliminary results at 1 week and 1 month postoperatively. Methods: IRIDEX MP3 laser cyclophotocoagulation was performed in 7 eyes of 7 patients under retrobulbar anaesthesia with lidocaine 2% in the operating room. Each eye received two treatments of 80-90s over the superior and inferior hemisphere, avoiding the temporal- and nasal-most clock hours. 810nm IRIDEX MP3 was set to 31,3% duty cycle (0,5ms treatment pulse followed by 1,1 ms of rest)...
April 2017: Romanian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29437582/number-of-incident-cases-of-the-main-eye-diseases-of-ageing-in-the-uk-biobank-cohort-projected-over-a-25-year-period-from-time-of-recruitment
#4
Parul Desai, Darwin C Minassian, Angela Reidy, Naomi Allen, Cathie Sudlow
OBJECTIVES: To estimate the number of new cases of age-related macular degeneration, cataract and glaucoma accruing in the UK Biobank cohort, over a period of 25 years from time of recruitment. Our secondary objective was to assess the statistical power of nested case-control studies of these eye diseases. We aimed to provide quantitative information relevant to UK Biobank's eye disease case ascertainment efforts and to the potential for UK Biobank-based research into the causes of eye disease...
February 6, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29429414/rapidly-progressive-neovascular-glaucoma-following-coronary-artery-bypass-graft-surgery-in-a-patient-with-type-1-diabetes-mellitus-a-case-report
#5
Vasant Raman, Rosemary Lambley
BACKGROUND: Proliferative diabetic retinopathy leading to vitreous hemorrhage, tractional retinal detachment, and neovascular glaucoma is a major cause of severe sight impairment in adults of working age worldwide. Neovascular glaucoma occurs in 2.5% of patients with proliferative diabetic retinopathy, which is difficult to treat and often leads to blindness. Onset of neovascular glaucoma with rapid progression to blindness within a few weeks of a successful coronary artery bypass graft procedure is not known with this clinical entity...
February 12, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29426968/clinical-experience-with-urgent-tube-shunt-implantation-through-the-ciliary-sulcus-in-phakic-eyes
#6
Adam J Weiner, Yotam Weiner, Melissa L Severson, Asher Weiner
PURPOSE: To review the clinical course and outcomes of 3 phakic, ischemic, and inflamed eyes in which we performed urgent tube shunt implantation through the ciliary sulcus without lensectomy. METHODS: This is a retrospective interventional case series. Three eyes of 3 diabetic patients with uncontrolled severe neovascular glaucoma, shallow anterior chambers with closed angles and poor view to the posterior segment, where concomitant lensectomy was not recommended due to uncontrolled uveitis and ischemia, underwent tube shunt implantation through the ciliary sulcus...
February 9, 2018: International Ophthalmology
https://www.readbyqxmd.com/read/29422012/a-clinical-analysis-of-vitrectomy-for-severe-vitreoretinopathy-in-patients-with-chronic-renal
#7
Long Su, Guannan Huang, Songtao Yin, Xia Hua, Xin Tang
BACKGROUND: The recent advancement in the management of chronic renal failure (CRF) has significantly increased the longevity of the patients, which increase the incidence of severe vitreoretinopathy. The vitrectomy is highly risky in this particular group of patients due to their systemic comorbidity. The timing surgical intervention is usually delayed because of the systemic conditions. This study is to evaluate the safety and effectiveness of 25-guage vitrectomy for severe vitreoretinopathy in the CRF patients...
February 8, 2018: BMC Ophthalmology
https://www.readbyqxmd.com/read/29409899/a-12-year-study-of-slotted-palladium-103-plaque-radiation-therapy-for-choroidal-melanoma-near-touching-or-surrounding-the-optic-nerve
#8
Abhilasha Maheshwari, Paul T Finger
PURPOSE: To present our 12-year experience with low energy photon, slotted eye plaque radiation therapy. DESIGN: Retrospective interventional case series METHODS: SETTING: The New York Eye Cancer Center. STUDY POPULATION: Fifty-two consecutive patients with uveal melanomas near, touching or surrounding the optic disc. INTERVENTION: Slotted eye plaque radiation therapy. MAIN OUTCOME MEASURES: change in visual acuity, local tumor control, radiation side effects, eye salvage and systemic metastases...
January 31, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29392320/a-naturally-fluorescent-mgp-transgenic-mouse-for-angiogenesis-and-glaucoma-longitudinal-studies
#9
Priyadarsini Asokan, Rajendra N Mitra, Ramesh Periasamy, Zongchao Han, Teresa Borrás
Purpose: Our goal was to generate and characterize a new mouse model in which only angiogenesis- and glaucoma-relevant tissues would be naturally fluorescent. The Matrix Gla (MGP) gene is highly expressed in vascular smooth muscle cells (VSMC) and trabecular meshwork (TM). We sought to direct our Mgp-Cre.KI mouse recombinase to VSMC/TM cells to produce their longitudinal fluorescent profiles. Methods: Homozygous Mgp-Cre.KI mice were crossed with Ai9 homozygous reporter mice harboring a loxP-flanked STOP cassette preventing transcription of a DsRed fluorescent protein (tdTomato)...
February 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29390305/intracameral-air-injection-during-ahmed-glaucoma-valve-implantation-in-neovascular-glaucoma-for-the-prevention-of-tube-obstruction-with-blood-clot-case-report
#10
Sung Ha Hwang, Chungkwon Yoo, Yong Yeon Kim, Dae Young Lee, Dong Heun Nam, Jong Yeon Lee
RATIONALE: Glaucoma drainage implant surgery is a treatment option for the management of neovascular glaucoma. However, tube obstruction by blood clot after Ahmed glaucoma valve (AGV) implantation is an unpredictable clinically challenging situation. PATIENT CONCERNS-DIAGNOSES-INTERVENTIONS: We report 4 cases using intracameral air injection for the prevention of the tube obstruction of AGV by blood clot. OUTCOMES: The first case was a 57-year-old female suffering from ocular pain because of a tube obstruction with blood clot after AGV implantation in neovascular glaucoma...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29380792/systemic-diffuse-large-b-cell-lymphoma-masquerading-as-neovascular-glaucoma
#11
Pritam Bawankar, Dipankar Das, Harsha Bhattacharjee, Shahinur Tayab, Nilutparna Deori, Vivek Paulbuddhe, Shriya Dhar, Apurba Deka
We describe a case of spontaneous hyphema associated with anterior uveitis presents in a 69-year old female as the prominent sign of the intraocular spread of systemic diffuse large B-cell lymphoma (DLBCL). She had a history of diabetes and initially misdiagnosed as neovascular glaucoma. Clinical history of systemic lymphoma, characteristic findings on B-scan ultrasonography and magnetic resonance imaging scan, and identification of atypical lymphoid cells in aqueous sample established the diagnosis of intraocular metastasis of systemic DLBCL...
February 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29361355/long-term-outcomes-of-total-exudative-retinal-detachments-in-stage-3b-coats-disease
#12
Albert S Li, Antonio Capone, Michael T Trese, Jonathan E Sears, Andres Kychenthal, Irina De la Huerta, Philip J Ferrone
PURPOSE: To evaluate the long-term outcomes of treatment of total exudative retinal detachments (ERDs) secondary to Coats disease (stage 3B) and the role of vitrectomy. DESIGN: Retrospective, observational case series. PARTICIPANTS: A total of 16 eyes in 16 patients undergoing treatment for total ERDs secondary to Coats disease with at least 5 years of follow-up. METHODS: We reviewed the records of patients with stage 3B Coats disease...
January 17, 2018: Ophthalmology
https://www.readbyqxmd.com/read/29324931/vitrectomy-with-fibrovascular-membrane-delamination-for-proliferative-diabetic-retinopathy-with-or-without-preoperative-avastin
#13
M Vasalaki, E Papavasileiou, C Garnavou-Xirou, S Velissaris, V Zygoura, D McHugh, T L Jackson
OBJECTIVE: To describe and compare 1. The changes in intraretinal microstructure using serial spectral domain optical coherence tomography (SD-OCT) preceding and following pars plana vitrectomy and delamination of fibrovascular membranes and 2. Intraoperative and postoperative complications in patients with proliferative diabetic retinopathy (PDR) who had preoperative Avastin (group A) or not (group B). SUBJECTS AND METHOD: This retrospective, interventional case series includes 113 eyes...
September 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29304266/small-gauge-endoscopy-guided-pneumatic-anterior-hyaloid-detachment-a-new-surgical-technique-for-combined-pars-plana-vitrectomy-and-pars-plana-glaucoma-drainage-implant
#14
Ali Dirani, Marina Ravagnani Ciongoli, Mark R Lesk, Flavio Rezende
BACKGROUND AND OBJECTIVE: Pars plana glaucoma drainage implant (GDI) occlusion is mainly related to entrapment of residual anterior vitreous gel in the implant. The aim of the present report is to describe a new surgical technique to induce pneumatic anterior hyaloid detachment in eyes with GDI. PATIENTS AND METHODS: This is a description of the surgical technique used to induce pneumatic anterior hyaloid detachment. RESULTS: The technique was used in two cases...
January 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29282399/chronic-retinal-necrosis-severely-complicated-by-neovascular-glaucoma-a-case-report
#15
Takanori Matsuoka, Kazunobu Asao, Noriyasu Hashida, Kohji Nishida
Background: Chronic retinal necrosis (CRN) is a rare chronic granular necrotizing retinitis that was first described in 2013. CRN is characterized by intraocular inflammation accompanied by occlusive vasculitis, granular retinitis, and slowly progressing necrosis around the retina in a host with partial immune dysfunction. Cytomegalovirus (CMV) is reported to be a causative agent. There are several ocular complications such as retinal detachment and neovascular glaucoma; however, there has been no description of a clinical manifestation of neovascular glaucoma in CRN...
September 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29276376/short-term-outcomes-after-ex-press-implantation-versus-trabeculectomy-alone-in-patients-with-neovascular-glaucoma
#16
Yoichiro Shinohara, Hideo Akiyama, Mikiya Magori, Shoji Kishi
Background: The purpose of this study was to investigate postoperative clinical outcomes in patients with neovascular glaucoma (NVG) who underwent trabeculectomy or EX-PRESS implantation and to identify predictors of successful EX-PRESS implantation. Methods: The study designed as a retrospective observational analysis and was set in a single tertiary center. Eighty-nine patients (89 eyes) with NVG, were treated using trabeculectomy alone (Trab group; n=39) or EX-PRESS implantation (EX group; n=50)...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29261555/treatment-of-idiopathic-retinal-vasculitis-aneurysms-and-neuroretinitis-irvan-with-photocoagulation-in-combination-with-systemic-immunosuppression
#17
Rohan Ameratunga, Mark Donaldson
BACKGROUND: Idiopathic retinal vasculitis, aneurysms, and neuroretinitis syndrome is a very rare primary retinal vasculitis. It seems to evolve in stages, where there is initially a florid vasculitis associated with aneurysm formation. Neuroretinitis and macula edema are common features. Subsequently, retinal ischemia ensues, leading to neovascularization. If untreated, further sight-threatening complications occur, including traction retinal detachment and secondary glaucoma. METHODS AND RESULTS: Here, we describe a patient with early idiopathic retinal vasculitis, aneurysms, and neuroretinitis syndrome, who was treated with a combination of systemic immunosuppression and localized photocoagulation...
December 19, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29259917/a-novel-suturing-technique-for-filtering-glaucoma-surgery-the-accordion-suture
#18
REVIEW
Mehmet Baykara, Basak Can Ermerak, Huri Sabur, Selim Genc
AIM: To present a novel scleral flap suturing technique for filtering glaucoma surgery in order to control high postoperative intraocular pressure (IOP). METHODS: Description of 'the accordion suture' technique for mitomycin C augmented trabeculectomy. In cases of postoperative high IOP, pulling the loop of the suture helps to lift up the scleral flap by an even pressure on both edges. By means of this technique, the scleral flap opens up in an "accordion" manner, thus preventing flap obstruction and providing adequate aqueous flow...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29259393/the-retina-rpe-proteome-in-chick-myopia-and-hyperopia-models-commonalities-with-inherited-and-age-related-ocular-pathologies
#19
Nina Riddell, Pierre Faou, Melanie Murphy, Loretta Giummarra, Rachael A Downs, Harinda Rajapaksha, Sheila G Crewther
Purpose: Microarray and RNA sequencing studies in the chick model of early optically induced refractive error have implicated thousands of genes, many of which have also been linked to ocular pathologies in humans, including age-related macular degeneration (AMD), choroidal neovascularization, glaucoma, and cataract. These findings highlight the potential relevance of the chick model to understanding both refractive error development and the progression to secondary pathological complications...
2017: Molecular Vision
https://www.readbyqxmd.com/read/29243035/systemic-lupus-erythematosus-and-ocular-involvement-an-overview
#20
REVIEW
Rosanna Dammacco
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease of undefined etiology and with remarkably heterogeneous clinical features. Virtually any organ system can be affected, including the eye. SLE-related eye involvement can be diagnosed in approximately one-third of the patients and is usually indicative of disease activity. An early diagnosis and the adoption of suitable therapeutic measures are necessary to prevent sight-threatening consequences, especially in patients with juvenile SLE. Periocular lesions, such as eyelid involvement and orbital inflammation, are relatively rare and, in case of orbital masses, may require a biopsy control...
December 14, 2017: Clinical and Experimental Medicine
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