Alex Daly, Lydia Newman, Alexandra Thomas, Alicia Munro, Cameron Spence, Joe Long, Jonathan Arnott, Kesta Durkin, David Layfield, Adam Heetun, Stephen Wootton, Ellen R Copson, Ramsey I Cutress
INTRODUCTION: Specific body composition markers derived from L3 axial computed tomography (CT) images predict clinical cancer outcomes, including chemotherapy toxicity and survival. However, this method is only applicable to those undergoing lumbar (L3) CT scanning, which is not universally conducted in early breast cancer cases. This study aimed to evaluate CT analysis at T4 as a feasible alternative marker of body composition in breast cancer. METHOD: All patients participated in the Investigating Outcomes from Breast Cancer: Correlating Genetic, Immunological, and Nutritional (BeGIN) Predictors observational cohort study (REC reference number: 14/EE/1297)...
2024: Frontiers in Nutrition