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https://www.readbyqxmd.com/read/28206898/fluoride-varnish-applications-in-preschoolers-and-dental-fluorosis-in-permanent-incisors-results-of-a-nested-cohort-study-within-a-clinical-trial
#1
Ana Paula Pires Dos Santos, Marcella Cristina Bordallo Malta, Mirian de Waele Souchois de Marsillac, Branca Heloisa de Oliveira
PURPOSE: To compare the prevalence and severity of fluorosis in the permanent maxillary incisors of children who had participated in a two-year randomized placebo-controlled clinical trial on fluoride varnish application in the primary dentition and to assess children's esthetic perception of their teeth. METHODS: Parents of 200 one- to four-year-old children who had received biannual applications of fluoride or placebo varnish were contacted four years after the end of the trial...
October 15, 2016: Pediatric Dentistry
https://www.readbyqxmd.com/read/28185728/skeletal-fluorosis-in-marsupials-a-comparison-of-bone-lesions-in-six-species-from-an-australian-industrial-site
#2
Clare Death, Graeme Coulson, Uwe Kierdorf, Horst Kierdorf, Richard Ploeg, Simon M Firestone, Ian Dohoo, Jasmin Hufschmid
In this study we explored the prevalence, type, location and severity of skeletal lesions in six species of Australian marsupial (Macropus giganteus, Notamacropus rufogriseus, Wallabia bicolor, Phascolarctos cinereus, Trichosurus vulpecula and Pseudocheirus peregrinus) from high and low-fluoride environments. Lesions occurred to varying extents in all species, and lesion distribution varied with biomechanical differences in gait and mastication. Bone fluoride levels increased with severity of periosteal hyperostosis...
February 6, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28170338/association-between-vitamin-d-receptor-gene-foki-polymorphism-and-skeletal-fluorosis-of-the-brick-tea-type-fluorosis-a-cross-sectional-case-control-study
#3
Dan Yang, Yang Liu, Yanru Chu, Qing Yang, Wei Jiang, Fuxun Chen, Dandan Li, Ming Qin, Dianjun Sun, Yanmei Yang, Yanhui Gao
BACKGROUND: Brick-tea type fluorosis is a public health concern in the north west area of China. The vitamin D receptor (VDR)-FokI polymorphism is considered to be a regulator of bone metabolism and calcium resorption. However, the association of VDR-FokI polymorphism with the risk of brick-tea type fluorosis has not been reported. MATERIALS AND METHODS: A cross sectional, case control study was conducted in three provinces (Inner Mongolia, Qinghai and Sinkiang) in China...
November 10, 2016: BMJ Open
https://www.readbyqxmd.com/read/28152004/prolactin-rs1341239-t-allele-may-have-protective-role-against-the-brick-tea-type-skeletal-fluorosis
#4
Bing-Yun Li, Yan-Mei Yang, Yang Liu, Jing Sun, Yan Ye, Xiao-Na Liu, Hong-Xu Liu, Zhen-Qi Sun, Mang Li, Jing Cui, Dian-Jun Sun, Yan-Hui Gao
OBJECTIVE: Prolactin (PRL) has been reported to be associated with increased bone turnover, and increased bone turnover is also a feature of skeletal fluorosis (SF). Autocrine/paracrine production of PRL is regulated by the extrapituitary promoter and a polymorphism in the extrapituitary PRL promoter at -1149 (rs1341239) is associated with disturbances of bone metabolism in other diseases. Here, we have investigated the possibility that the rs1341239 polymorphism is associated with SF, which results from the consumption of brick tea...
2017: PloS One
https://www.readbyqxmd.com/read/28131910/polymorphisms-in-genes-involved-in-enamel-development-are-associated-with-dental-fluorosis
#5
Erika Calvano Küchler, Patricia Nivoloni Tannure, Daniela Silva Barroso de Oliveira, Senda Charone, Paulo Nelson-Filho, Raquel Assed Bezerra da Silva, Marcelo de Castro Costa, Leonardo Santos Antunes, Mônica Diuana Calasans Maia, Lívia Azeredo Alves Antunes
OBJECTIVE: To evaluate the association between polymorphisms in DLX1, DLX2, MMP13, TIMP1 and TIMP2 genes with dental fluorosis (DF) phenotype. DESIGN: Four hundred and eighty one subjects (108 with DF and 373 DF free) from 6 to 18 years of age were recruited. This population lived in Rio de Janeiro, a city with fluoridation of public water supplies. DF was assessed using the Deańs index modified. Only erupted permanent teeth were assessed. Genetic polymorphisms in DLX1, DLX2, MMP13, TIMP1 and TIMP2 were analyzed by real-time PCR from genomic DNA...
January 18, 2017: Archives of Oral Biology
https://www.readbyqxmd.com/read/28120305/safety-evaluation-of-fluoride-content-in-tea-infusions-consumed-in-the-azores-a-volcanic-region-with-water-springs-naturally-enriched-in-fluoride
#6
Diana Paula Silva Linhares, Patrícia Ventura Garcia, Leslie Amaral, Teresa Ferreira, Armindo Dos Santos Rodrigues
Tea is the second most commonly consumed beverage in the world. It is well recognized that the consumption of tea in high quantities can promote the development of fluorosis. The main objective of this study is to estimate the exposure to fluoride in the Azores through drinking tea prepared with water from different volcanic locations, by i) investigating the fluoride (F) content of various commercial brands of tea (Camellia sinensis) marketed in Azores and ii) comparing tea releasing rates of F according to brewing time, considering the fluoride concentration in the different types of water used for the infusion...
January 24, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28117855/marginal-sealing-of-a-porcelain-%C3%A2-laminate-veneer-luted-with-%C3%A2-three-different-resin-cements-%C3%A2-on-fluorosed-teeth
#7
Fereshteh Shafiei, Mahtab Memarpour, Zahra Jowkar
AIM: The purpose of this study was to investigate the sealing ability of three different resin cements for the luting of a porcelain laminate veneer (PLV) to the enamel and dentin of fluorosed teeth. MATERIALS AND METHOD: Thirty incisors with moderate fluorosis according to the Thylstrup-Fejerskov Index (TFI = 4 to 6) received a veneer preparation with dentin margins at the gingival third. The IPS Empress (Ivoclar Vivadent) veneers were luted to the teeth of three groups (n = 10) using three different resin cements: Group 1: Excite DSC/Variolink II - etch-and-rinse (E&R), Group 2: ED Primer II/Clearfil Esthetic - self-etch (SE), Group 3: RelyX Unicem - self-adhesive (SA)...
2017: International Journal of Esthetic Dentistry
https://www.readbyqxmd.com/read/28116437/-study-of-the-effect-of-fluoride-removal-agent-and-microabrasion-technology-in-led-teeth-whitening-of-dental-fluorosis
#8
Yan Jia, Rong Zhang, Hong-Xia Luo, Ping Li, Chun-Lei Zhang
PURPOSE: To evaluate the effect of fluoride removal agent and microabrasion technology in LED teeth whitening of dental fluorosis. METHODS: One hundred and twelve patients with moderate dental fluorosis treated from August 2012 to July 2015 were divided into experimental group and control group according to random number table, with 61 cases in each group. In addition to pretreatment for all patients, patients in the control group were given combined treatment of Beyond LED whitening and fluoride removal agent; while patients in the experimental group were given microabrasion before LED whitening, with the same subsequent treatment process as that in the control group...
October 2016: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/28110134/concentrations-of-fluoride-in-water-and-plasma-for-us-children-and-adolescents-data-from-nhanes-2013-2014
#9
Ram B Jain
For the first time, for 2013-2014, as part of ongoing National Health and Nutrition Examination Survey, data for fluoride concentrations in water and plasma for U.S. children and adolescents were released in the public domain. This study was undertaken to investigate how fluoride concentrations vary in water and plasma with age, gender, race/ethnicity, housing ownership, use of prescription fluoride drops and/or tablets, exposure to environmental tobacco smoke, and recent use of tobacco products (among adolescents)...
January 17, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28079131/matrix-metallopeptidase-2-gene-rs2287074-polymorphism-is-associated-with-brick-tea-skeletal-fluorosis-in-tibetans-and-kazaks-china
#10
Junrui Pei, Bingyun Li, Yang Liu, Xiaona Liu, Mang Li, Yanru Chu, Qing Yang, Wei Jiang, Fuxun Chen, Gottfried M Darko, Yanmei Yang, Yanhui Gao
Brick tea skeletal fluorosis is still a public health issue in the north-western area of China. However its pathogenesis remains unknown. Our previous study reveals that the severity of skeletal fluorosis in Tibetans is more serious than that in Kazaks, although they have similar fluoride exposure, suggesting the onset of brick tea type skeletal fluorosis might be genetically influenced. Here we show that MMP-2 rs2287074 SNP (G/A), but not rs243865, was associated with Brick tea type fluorosis in Tibetans and Kazaks, China...
January 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28063715/probabilistic-risk-assessment-of-chinese-residents-exposure-to-fluoride-in-improved-drinking-water-in-endemic-fluorosis-areas
#11
Li E Zhang, Daizheng Huang, Jie Yang, Xiao Wei, Jian Qin, Songfeng Ou, Zhiyong Zhang, Yunfeng Zou
Studies have yet to evaluate the effects of water improvement on fluoride concentrations in drinking water and the corresponding health risks to Chinese residents in endemic fluorosis areas (EFAs) at a national level. This paper summarized available data in the published literature (2008-2016) on water fluoride from the EFAs in China before and after water quality was improved. Based on these obtained data, health risk assessment of Chinese residents' exposure to fluoride in improved drinking water was performed by means of a probabilistic approach...
March 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28032049/the-efficiency-of-child-formula-dentifrices-containing-different-calcium-and-phosphate-compounds-on-artificial-enamel-caries
#12
Praphasri Rirattanapong, Kadkao Vongsavan, Chavengkiat Saengsirinavin, Ploychompoo Khumsub
OBJECTIVES: Fluoride toothpaste has been extensively used to prevent dental caries. However, the risk of fluorosis is concerning, especially in young children. Calcium phosphate has been an effective remineralizing agent and is present in commercial dental products, with no risk of fluorosis to users. This in vitro study aimed to compare the effects of different calcium phosphate compounds and fluoride-containing dentifrices on artificial caries in primary teeth. MATERIALS AND METHODS: Fifty sound primary incisors were coated with nail varnish, leaving two 1 mm(2) windows on the labial surface before immersion in demineralizing solution for 96 hours to produce artificial enamel lesions...
November 2016: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/28032042/dental-fluorosis-fluoride-in-urine-and-nutritional-status-in-adolescent-students-living-in-the-rural-areas-of-guanajuato-mexico
#13
Aguilar-Díaz Fatima Del Carmen, de la Fuente-Hernández Javier, Cintra-Viveiro Cristina Aline
OBJECTIVE: The aim of this study was to assess urine fluoride concentration, nutritional status, and dental fluorosis in adolescent students living in the rural areas of Guanajuato, Mexico. MATERIALS AND METHODS: A cross-sectional study was conducted including participants aged 11-20 years. The presence and severity of dental fluorosis was registered according to the Thylstrup and Fejerskov index (TFI) criteria. Anthropometric measures were also recorded. Urine sample of the first morning spot was recollected to assess urine fluoride concentration by using the potentiometric method with an ion-selective electrode...
November 2016: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/28025807/risk-factors-and-prevalence-of-dental-fluorosis-and-dental-caries-in-school-children-of-north-india
#14
Kavita Plaka, Khaiwal Ravindra, Suman Mor, Krishan Gauba
The aim of the study was to assess the prevalence of dental fluorosis, dental caries, and associated risk factors in the school children of district Fatehgarh Sahib, Punjab, India, using a cross-sectional study design. Oral health status of children aged between 8 and 15 years was assessed using World Health Organization (WHO) 2013 criteria. Dental fluorosis was assessed using Dean's index, and dental caries were recorded using decayed, missing, filled/decayed, extracted, filled (DMF/def) indices. Four hundred school children were examined, of which 207 were in the 8-11-year-old group and 193 were in the 12-15-year-old group...
January 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/27990615/sodium-fluoride-does-not-affect-the-working-memory-and-number-of-pyramidal-cells-in-rat-medial-prefrontal-cortex
#15
Zulhaini Sartika A Pulungan, Zaenal Muttaqien Sofro, Ginus Partadiredja
Fluoride is a chemical compound known to bring about fluorosis. It is thought to disrupt the central nervous system because of its ability to induce excitotoxicity and oxidative stress. Any damage of pyramidal cells in the prefrontal cortex would result in cognitive function and working memory regulation disorders. The present study aimed at investigating the effects of sodium fluoride (NaF) on the working memory and estimated total number of medial prefrontal cortex pyramidal cells of adult male rats. Thirty-two male Wistar rats were assigned into four groups, namely control and three treated groups receiving 5, 10 and 20 mg/kg BW, respectively, of oral NaF solution for 30 days...
December 18, 2016: Anatomical Science International
https://www.readbyqxmd.com/read/27917370/multiple-myeloma-like-spinal-mri-findings-in-skeletal-fluorosis-an-unusual-presentation-of-fluoride-toxicity-in-human
#16
Javed Ahsan Quadri, Mohd Meraj Alam, Saba Sarwar, Ashraf Ghanai, A Shariff, Taposh K Das
Endemic fluorosis is a worldwide environmental problem due to excessive fluoride, commonly due to increased drinking water fluoride levels but sometimes due to other sources such as food with high fluoride content. In India, 21 of the 35 states are known to have health problems associated with fluoride toxicity. The present report is a case of a 50-year-old female who was seen with progressive spinal complications and a MRI of the spine suggestive of multiple myeloma. The MRI of the lumbosacral spine showed a diffuse and heterogeneous marrow signal of the lower dorsal and lumbosacral vertebrae...
2016: Frontiers in Oncology
https://www.readbyqxmd.com/read/27871895/protective-effect-of-lycopene-on-fluoride-induced-ameloblasts-apoptosis-and-dental-fluorosis-through-oxidative-stress-mediated-caspase-pathways
#17
Weishan Li, Binghua Jiang, Xianglin Cao, Yongjiang Xie, Ting Huang
Fluoride is an environmental toxicant and induces dental fluorosis and oxidative stress. Lycopene (LYC) is an effective antioxidant that is reported to attenuate fluoride toxicity. To determine the effects of LYC on sodium fluoride (NaF) -induced teeth and ameloblasts toxicity, rats were treated with NaF (10 mg/kg) and/or LYC (10 mg/kg) by orally administration for 5 weeks; ameloblasts were treated with NaF (5 mM) and/or LYC (2 μM) for 6 h. We found that the concentrations of fluoride, malondialdehyde (MDA) and reactive oxygen species (ROS), gene expressions and activities of Caspase-9 and Caspase-3, and the gene expressions of Bax were significantly decreased, while the activities of superoxide dismutase (SOD) and glutathione peroxidase (GPX), the gene expression of Bcl-2 were significantly increased in the LYC + NaF-treated rats group; concentrations of MDA and ROS, gene expressions and activities of Caspase-9 and Caspase-3, and the gene expression of Bax, and ameloblasts apoptosis rate were significantly decreased, while the activities of SOD and GPX, the gene expression of Bcl-2 were significantly increased in the LYC + NaF-treated ameloblasts group...
January 5, 2017: Chemico-biological Interactions
https://www.readbyqxmd.com/read/27847422/effect-of-tamarindus-indica-leaf-powder-on-plasma-concentrations-of-copper-zinc-and-iron-in-fluorotic-cows
#18
Pinaki Samal, R C Patra, A R Gupta, S K Mishra, D Jena, D Satapathy
AIM: The main objective of the study was to determine the deleterious effect of fluoride on plasma trace minerals of fluorotic cattle and to evaluate the effect of Tamarindus indica leaf powder toward correction of the same. MATERIALS AND METHODS: A total of 30 cattle exhibiting chronic sign of fluorosis and 10 healthy cattle from nonfluorotic area were incorporated in this study. Fluorotic cattle were divided into three equal groups consisting of 10 cattle each...
October 2016: Veterinary World
https://www.readbyqxmd.com/read/27843259/prevalence-of-dental-fluorosis-and-associated-risk-factors-in-bagalkot-district-karnataka-india
#19
Taranatha Mahantesha, Uma B Dixit, Ramesh P Nayakar, Devasya Ashwin, Naveen K Ramagoni, Vijaya P Kamavaram Ellore
INTRODUCTION: An earlier epidemiological study by these authors revealed fluorosis at very low levels of fluoride concentrations in drinking water. AIM: The objective of present study was to investigate risk factors of dental fluorosis in permanent teeth in the villages of northern Karnataka, India. MATERIALS AND METHODS: The present survey was carried out in three villages of Hungund Taluk, Bagalkot District, Karnataka, India, with the fluoride concentration of 0...
July 2016: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/27836268/fluoride-enrichment-in-an-alluvial-aquifer-with-its-subsequent-effect-on-human-health-in-birbhum-district-west-bengal-india
#20
D Mondal, S Gupta, D V Reddy, G Dutta
This research work primarily deals with the geochemistry and genesis of fluoride (F(-)) in an alluvial aquifer with an emphasis on prevalence of dental and skeletal fluorosis among the endemic population. Hydrogeochemical outcomes reveal that chemical weathering and ion-exchange phenomena are the two dominant processes that make study area groundwater into NaHCO3 water type. Presence of intercalated zeolite rich sediments (FTotal 412-446 mg/kg) having higher ion-exchange capacity (120-125 meq/100 g) within the aquifer is the source and mobilizing factors of F(-) in groundwater respectively...
February 2017: Chemosphere
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