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Catheter associated urinary tract infection

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https://www.readbyqxmd.com/read/27914268/anti-adhesive-antimicrobial-peptide-coating-prevents-catheter-associated-infection-in-a-mouse-urinary-infection-model
#1
Kai Yu, Joey C Y Lo, Mei Yan, Xiaoqiang Yang, Donald E Brooks, Robert E W Hancock, Dirk Lange, Jayachandran N Kizhakkedathu
Catheter-associated urinary tract infections (CAUTIs) represent one of the most common hospital acquired infections with significant economic consequences and increased patient morbidity. CAUTIs often start with pathogen adhesion and colonization on the catheter surface followed by biofilm formation. Current strategies to prevent CAUTIs are insufficiently effective and antimicrobial coatings based on antimicrobial peptides (AMPs) hold promise in curbing CAUTIs. Here we report an effective surface tethering strategy to prepare AMP coatings on polyurethane (PU), a common biomedical plastic used for catheter manufacture, by using an anti-adhesive hydrophilic polymer coating...
November 24, 2016: Biomaterials
https://www.readbyqxmd.com/read/27899416/peritoneal-dialysis-access-revision-in-children-causes-interventions-and-outcomes
#2
Dagmara Borzych-Duzalka, T Fazil Aki, Marta Azocar, Colin White, Elizabeth Harvey, Sevgi Mir, Marta Adragna, Erkin Serdaroglu, Rajiv Sinha, Charlotte Samaille, Juan Jose Vanegas, Jameela Kari, Lorena Barbosa, Arvind Bagga, Monica Galanti, Onder Yavascan, Giovanna Leozappa, Maria Szczepanska, Karel Vondrak, Kei-Chiu Tse, Franz Schaefer, Bradley A Warady
BACKGROUND AND OBJECTIVES: Little published information is available about access failure in children undergoing chronic peritoneal dialysis. Our objectives were to evaluate frequency, risk factors, interventions, and outcome of peritoneal dialysis access revision. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Data were derived from 824 incident and 1629 prevalent patients from 105 pediatric nephrology centers enrolled in the International Pediatric Peritoneal Dialysis Network Registry between 2007 and 2015...
November 29, 2016: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/27895127/the-pathogenic-potential-of-proteus-mirabilis-is-enhanced-by-other-uropathogens-during-polymicrobial-urinary-tract-infection
#3
Chelsie E Armbruster, Sara N Smith, Alexandra O Johnson, Valerie DeOrnellas, Kathryn A Eaton, Alejandra Yep, Lona Mody, Weisheng Wu, Harry L T Mobley
Urinary catheter use is prevalent in health care settings, and polymicrobial colonization by urease-positive organisms, such as Proteus mirabilis and Providencia stuartii, commonly occurs with long-term catheterization. We previously demonstrated that coinfection with P. mirabilis and P. stuartii increased overall urease activity in vitro and disease severity in a model of urinary tract infection (UTI). In this study, we expanded these findings to a murine model of catheter-associated UTI (CAUTI), delineated the contribution of enhanced urease activity to coinfection pathogenesis, and screened for enhanced urease activity with other common CAUTI pathogens...
November 28, 2016: Infection and Immunity
https://www.readbyqxmd.com/read/27890335/device-associated-infections-in-a-paediatric-intensive-care-unit-in-pakistan
#4
A Haque, S A Ahmed, Z Rafique, Q Abbas, H Jurair, S A Ali
This study assessed the effect of implementation of active infection control and surveillance on the occurrence of device-associated infections (DAIs) in a paediatric intensive care unit (PICU) from 2012 to 2015. There were 1378 patients, equating to 4632 patient-days, on the PICU, and 29 DAI episodes, giving an incidence rate of 2.1% and an incidence density rate of 6.26 per 1000 patient-days. The rates of central-line-associated bloodstream infections, ventilator-associated pneumonia and catheter-related urinary tract infections were 7/1000 central-line-days, 1...
November 4, 2016: Journal of Hospital Infection
https://www.readbyqxmd.com/read/27881213/impact-and-limitations-of-the-2015-national-health-and-safety-network-case-definition-on-catheter-associated-urinary-tract-infection-rates
#5
Ana Cecilia Bardossy, Rachna Jayaprakash, Anjali C Alangaden, Patricia Starr, Odaliz Abreu-Lanfranco, Katherine Reyes, Marcus J Zervos, George J Alangaden
Application of the new 2015 NHSN definition of catheter-associated urinary tract infection (CAUTI) in intensive care units reduced CAUTI rates by ~50%, primarily due to exclusion of candiduria. This significant reduction in CAUTI rates resulting from the changes in the definition must be considered when evaluating effectiveness of CAUTI prevention programs. Infect Control Hosp Epidemiol 2016;1-3.
November 24, 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/27876075/chlorhexidine-bathing-and-health-care-associated-infections-among-adult-intensive-care-patients-a-systematic-review-and-meta-analysis
#6
Steven A Frost, Mari-Cris Alogso, Lauren Metcalfe, Joan M Lynch, Leanne Hunt, Ritesh Sanghavi, Evan Alexandrou, Kenneth M Hillman
BACKGROUND: Health care-associated infections (HAI) have been shown to increase length of stay, the cost of care, and rates of hospital deaths (Kaye and Marchaim, J Am Geriatr Soc 62(2):306-11, 2014; Roberts and Scott, Med Care 48(11):1026-35, 2010; Warren and Quadir, Crit Care Med 34(8):2084-9, 2006; Zimlichman and Henderson, JAMA Intern Med 173(22):2039-46, 2013). Importantly, infections acquired during a hospital stay have been shown to be preventable (Loveday and Wilson, J Hosp Infect 86:S1-70, 2014)...
November 23, 2016: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/27875382/incorporation-of-leadership-rounds-in-cauti-prevention-efforts
#7
Suzanne Purvis, Gregory D Kennedy, Mary Jo Knobloch, Amy Marver, John Marx, Susan Rees, Nasia Safdar, Daniel Shirley
Leadership engagement is an important aspect of integrating best practices at the bedside. The catheter-associated urinary tract infection (CAUTI) prevention workgroup at our academic medical center implemented leadership rounding in partnership with clinical staff to increase participation in CAUTI prevention initiatives on inpatient units. There was an associated decrease in urinary catheter utilization and CAUTI rates. Implementation of leadership rounds should be considered as a part of comprehensive CAUTI prevention efforts in health care settings...
November 21, 2016: Journal of Nursing Care Quality
https://www.readbyqxmd.com/read/27871828/pain-associated-with-urethral-catheterization-is-reduced-in-males-by-simultaneous-voiding-maneuver
#8
Kobi Stav, Yishai H Rappaport, Ilia Beberashvili, Amnon Zisman
OBJECTIVE: To assess whether urethral pain during male catheterization can be reduced if the patient is instructed to void during the insertion of the catheter. METHODS: 96 males (age 66±13) who were referred for multichannel Urodynamic study were prospectively randomized to 2 groups according to the catheter insertion technique: (1) patients were instructed to void during catheterization; (2) no guidance prior or during catheterization. Exclusion criteria were: use of analgesics within the previous 24 hours, active urinary tract infection, indwelling urethral catheter, pre-existing urethral pain, known urethral stricture or inability to cooperate with pain assessment due to mental disorders...
November 18, 2016: Urology
https://www.readbyqxmd.com/read/27869492/risk-factors-for-development-of-primary-bladder-squamous-cell-carcinoma
#9
K V Manley, R Hubbard, D Swallow, W Finch, S J Wood, S M Biers
INTRODUCTION The aim of this study was to investigate the prevalence of risk factors for primary squamous cell carcinoma (SCC) of the bladder. MATERIALS A total of 90 cases of primary SCC of the bladder were identified through multicentre analysis. Patient demographics, stage and grade of cancer at presentation, management and outcomes were recorded. The presence of known risk factors (catheter use, neuropathic bladder, smoking history, recurrent urinary tract infection and bladder stones) was also documented...
November 21, 2016: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/27858954/how-often-do-clinically-diagnosed-catheter-associated-urinary-tract-infections-in-nursing-homes-meet-standardized-criteria
#10
Chelsie E Armbruster, Katherine Prenovost, Harry L T Mobley, Lona Mody
OBJECTIVES: To determine the relationship between clinically diagnosed catheter-associated urinary tract infection (CAUTI) and standardized criteria and to assess microorganism-level differences in symptom burden in a cohort of catheterized nursing home (NH) residents. DESIGN: Post hoc analysis of a prospective longitudinal study. SETTING: Twelve NHs in southeast Michigan. PARTICIPANTS: NH residents with indwelling urinary catheters (n = 233; 90% white, 52% male, mean age 73...
November 14, 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27852357/a-multifaceted-approach-to-reduction-of-catheter-associated-urinary-tract-infections-in-the-intensive-care-unit-with-an-emphasis-on-stewardship-of-culturing
#11
Katherine M Mullin, Christopher S Kovacs, Cynthia Fatica, Colette Einloth, Elizabeth A Neuner, Jorge A Guzman, Eric Kaiser, Venu Menon, Leticia Castillo, Marc J Popovich, Edward M Manno, Steven M Gordon, Thomas G Fraser
BACKGROUND Catheter-associated urinary tract infections (CAUTIs) are among the most common hospital-acquired infections (HAIs). Reducing CAUTI rates has become a major focus of attention due to increasing public health concerns and reimbursement implications. OBJECTIVE To implement and describe a multifaceted intervention to decrease CAUTIs in our ICUs with an emphasis on indications for obtaining a urine culture. METHODS A project team composed of all critical care disciplines was assembled to address an institutional goal of decreasing CAUTIs...
November 17, 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/27850899/1263-intervention-for-prevention-reducing-catheter-associated-urinary-tract-infection-in-the-icu
#12
Elise Kumar, Paul Yodice, Fariborz Rezai, Kristin Fless, Nirav Mistry, Vagram Ovnanian, Kaitlin Kumar
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27850327/688-catheter-removal-strategies-and-the-illusion-of-catheter-associated-urinary-tract-infection-rates
#13
Gary Collin, Michael Raczynski, Charlene Scott
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27850298/659-impact-of-a-urine-culture-ordering-process-on-catheter-associated-urinary-tract-infections-in-an-icu
#14
Katherine Shea, Athena Hobbs, Jonathan Hecht, Caroline Burger, Lynda Watkins, Mitchell Daley, Robert Huth
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27837224/-prevention-of-catheter-associated-urinary-tract-infections
#15
K F Becher, S Nitschmann
No abstract text is available yet for this article.
November 11, 2016: Der Internist
https://www.readbyqxmd.com/read/27824737/povidone-iodine-0-05-chlorhexidine-gluconate-or-water-for-periurethral-cleaning-before-indwelling-urinary-catheterization-in-a-pediatric-intensive-care-a-randomized-controlled-trial
#16
Duygu Sönmez Düzkaya, Gülzade Uysal, Gülçin Bozkurt, Tülay Yakut, Agop Çitak
PURPOSE: The aim of this study was to evaluate the efficacy of periurethral cleaning with 10% povidone-iodine, 0.05% chlorhexidine gluconate, or sterile water in preventing catheter-associated urinary tract infections (CAUTIs) prior to indwelling urinary catheter insertion in a pediatric intensive care unit. A secondary aim was to identify pathogens resulting in CAUTIs in this group. DESIGN: Randomized controlled trial. SUBJECTS AND SETTING: One hundred twenty-two patients cared for in a pediatric intensive care unit of a university hospital between September 2012 and December 2013 participated in the study...
November 7, 2016: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/27816141/urinary-tract-infections
#17
REVIEW
Carol E Chenoweth, Sanjay Saint
Catheter-associated urinary tract infection (CAUTI) remains one of the most prevalent, yet preventable, health care-associated infections and predominantly occurs in patients with indwelling urinary catheters. Targeted strategies for prevention of CAUTI include limiting urinary catheter use; physician reminder systems, nurse-initiated discontinuation protocols, and automatic stop orders have successfully decreased catheter duration. Alternatives to indwelling catheters should be considered in appropriate patients...
December 2016: Infectious Disease Clinics of North America
https://www.readbyqxmd.com/read/27813386/retroperitoneoscopic-pyelolithotomy-a-good-alternative-treatment-for-renal-pelvic-calculi-in-children
#18
Bruno Nicolino Cezarino, Rubens Park, Paulo Renato Marcelo Moscardi, Roberto Iglesias Lopes, Francisco T Denes, Miguel Srougi
INTRODUCTION: Nephrolitiasis, once considered an adult disease, has become increasingly prevalent in children, with na increase from 6% to 10 % annually in past 25 years. Kidney stones in pediatric population can result from metabolic diseases in up to 50% of children affected. Other factors associated with litiasis are infection, dietary factors, and anatomic malformations of urinary tract. Standard treatment procedures for pediatric population are similar to adult population. Extracorporeal shock wave lithotripsy (ESWL), ureterorenoscopy (URS), percutaneous nepfrolithotomy (PCNL), as well as laparoscopic and retroperitoneoscopic approaches can be indicated in selected cases...
November 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/27805758/exploring-relationships-of-catheter-associated-urinary-tract-infection-and-blockage-in-people-with-long-term-indwelling-urinary-catheters
#19
Mary H Wilde, James M McMahon, Hugh F Crean, Judith Brasch
AIMS: The aims were to describe and explore relationships among catheter problems in long-term indwelling urinary catheter users, including excess health care utilization for treating catheter problems. BACKGROUND: Long-term urinary catheter users experience repeated problems with catheter-related urinary tract infection (CAUTI) and blockage of the device, yet little has been reported of the patterns and relationships among relevant catheter variables. DESIGN: Secondary data analysis was conducted from a sample in a randomized clinical trial, using data from the entire sample of 202 persons over 12 months' participation...
November 2, 2016: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/27795399/antibody-based-therapy-for-enterococcal-catheter-associated-urinary-tract-infections
#20
Ana L Flores-Mireles, Jennifer N Walker, Aaron Potretzke, Henry L Schreiber, Jerome S Pinkner, Tyler M Bauman, Alyssa M Park, Alana Desai, Scott J Hultgren, Michael G Caparon
: Gram-positive bacteria in the genus Enterococcus are a frequent cause of catheter-associated urinary tract infection (CAUTI), a disease whose treatment is increasingly challenged by multiantibiotic-resistant strains. We have recently shown that E. faecalis uses the Ebp pilus, a heteropolymeric surface fiber, to bind the host protein fibrinogen as a critical step in CAUTI pathogenesis. Fibrinogen is deposited on catheters due to catheter-induced inflammation and is recognized by the N-terminal domain of EbpA (EbpA(NTD)), the Ebp pilus's adhesin...
October 25, 2016: MBio
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