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https://www.readbyqxmd.com/read/29656558/deep-ultraviolet-nonlinear-optical-crystal-cs%C3%A2-al%C3%A2-b%C3%A2-o%C3%A2-%C3%A2-o-a-benign-member-of-sr%C3%A2-be%C3%A2-bo%C3%A2-%C3%A2-o-family-with-al%C3%A2-b%C3%A2-o%C3%A2-%C3%A2-o-%C3%A2-double-layers
#1
Zhi Fang, Xingxing Jiang, Meihong Duan, Zhanyu Hou, Changcheng Tang, Mingjun Xia, Lijuan Liu, Zheshuai Lin, Feidi Fan, Lei Bai, Chuangtian Chen
For the explorations on deep ultraviolet (DUV) nonlinear optical (NLO) borates, a type of important optoelectronic materials, (BO3)3- group is long-termly regarded as the sole microscopic optical-active unit and the toxic Be-containing raw materials are frequently-adopted. Herein, a new DUV NLO crystal Cs2Al2(B3O6)2O (CABO) was designed and synthesized by simultaneously replacing the (BO3)3- groups and Be2+ cations in Sr2Be2(BO3)2O that possesses a favorable structure for large NLO response by (B3O6)3- units and Al3+ cations through cosubstitution approach...
April 15, 2018: Chemistry: a European Journal
https://www.readbyqxmd.com/read/29656354/distribution-relationship-and-risk-assessment-of-toxic-heavy-metals-in-walnuts-and-growth-soil
#2
Yongxiang Han, Zhanglin Ni, Shiliang Li, Minghua Qu, Fubin Tang, Runhong Mo, Caifen Ye, Yihua Liu
Walnut is one of the most popular nuts worldwide and contains various mineral nutrients. Little is known, however, about the relationship between toxic heavy metals in walnuts and growth soil. In this study, we investigated the distribution, relationship, and risk assessment of five toxic heavy metals-lead (Pb), arsenic (As), chromium (Cr), cadmium (Cd), and mercury (Hg)-in walnuts and growth soil in the main production areas of China. The results showed that the main heavy metal pollution in walnut and soil was Pb and Cd...
April 14, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29656346/hip-fracture-patients-who-experience-a-greater-fluctuation-in-rdw-during-hospital-course-are-at-heightened-risk-for-all-cause-mortality-a-prospective-study-with-2-year-follow-up
#3
P Yin, H Lv, Y Li, Y Meng, L Zhang, L Zhang, P Tang
This study aims to detect whether there remains valuable prognostic information in fluctuation of red cell distribution width (RDW) in hip fracture patients. Results show that this readily available parameter may provide a more effective strategy for assessment of mortality risk, therefore providing a reference for clinical planning and decision-making. INTRODUCTION: Prognostic values have been found in the fluctuation of some hematologic parameters. The red cell distribution width (RDW) routinely reported with all complete blood cell counts (CBC) has proven to be associated with poor outcomes in various diseases...
April 14, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29656339/role-of-ampk-in-atherosclerosis-via-autophagy-regulation
#4
REVIEW
Hanxiao Ou, Chuhao Liu, Wenjie Feng, Xinwen Xiao, Shengsong Tang, Zhongcheng Mo
Atherosclerosis is characterized by the accumulation of lipids and deposition of fibrous elements in the vascular wall, which is the primary cause of cardiovascular diseases. Adenosine monophosphate-activated protein kinase (AMPK) is a metabolic sensor of energy metabolism that regulates multiple physiological processes, including lipid and glucose metabolism and the normalization of energy imbalances. Overwhelming evidence indicates that AMPK activation markedly attenuates atherosclerosis development. Autophagy inhibits cell apoptosis and inflammation and promotes cholesterol efflux and efferocytosis...
April 12, 2018: Science China. Life Sciences
https://www.readbyqxmd.com/read/29656303/spondylodiscitis-following-endovascular-abdominal-aortic-aneurysm-repair-imaging-perspectives-from-a-single-centre-s-experience
#5
Ramin Mandegaran, Christopher S W Tang, Erlick A C Pereira, Ali Zavareh
OBJECTIVE: Very few reports have previously described spondylodiscitis as a potential complication of endovascular aortic aneurysm repair (EVAR). We present to our knowledge the first case series of spondylodiscitis following EVAR based on our institution's experience over an 11-year period. Particular attention is paid to the key imaging features and challenges encountered when performing spinal imaging in this complex patient group. MATERIALS AND METHODS: Of 1,847 patients who underwent EVAR at our institution between January 2006 and January 2017, a total of 9 patients were identified with imaging features of spondylodiscitis (0...
April 14, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29656289/high-concentration-of-glial-cell-line-derived-neurotrophic-factor-protects-primary-astrocytes-from-apoptosis
#6
Yuqian Wang, Yuxia Qin, Tingwen Guo, Chuanxi Tang, Liyun Liu, Dianshuai Gao
BACKGROUND: Studies have shown that astrocytes play an important role in a variety of biological processes, so damage to astrocytes can cause a series of related diseases. Glial cell line-derived neurotrophic factor (GDNF) has always been considered a protective factor for dopamine neurons. However, it remains unclear whether GDNF has a protective effect on glial cells, especially astrocytes. In this study, we put forward the hypothesis that a high concentration of GDNF in the microenvironment of astrocytes exerts an inhibitory effect on the apoptosis of astrocytes by DNA-damaging reagents...
April 13, 2018: Developmental Neuroscience
https://www.readbyqxmd.com/read/29656222/prolactin-induced-protein-pip-is-a-potential-biomarker-for-early-stage-and-malignant-breast-cancer
#7
Anju Gangadharan, Themba Nyirenda, Kishan Patel, Nydia Jaimes-Delgadillo, Dominique Coletta, Takemi Tanaka, Ayal C Walland, Zena Jameel, Srinivasa Vedantam, Sittinon Tang, Ciaran Mannion, Grace Y Lee, Andre Goy, Andrew Pecora, K Stephen Suh
OBJECTIVES: Breast cancer (BC) is the second leading cause of cancer-related mortality in women. Bioinformatic analysis and expression screening showed that Prolactin Induced Protein (PIP) was differentially expressed in BC. The objective of this investigation was to characterize the expression pattern of PIP, an aspartyl proteinase, in malignant and non-malignant breast tissues. MATERIALS AND METHODS: Real time quantitative PCR was employed to analyze PIP and androgen receptor (AR) mRNA levels in BC cell lines and 190 normal tissues and tumor samples...
April 12, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29656200/photoinduced-anticancer-activity-studies-of-iridium-iii-complexes-targeting-mitochondria-and-tubules
#8
Wen-Yao Zhang, Qian-Yan Yi, Yang-Jie Wang, Fan Du, Miao He, Bing Tang, Dan Wan, Yun-Jun Liu, Hong-Liang Huang
Three new iridium (III) complexes [Ir (ppy)2 (ipbc)](PF6 ) (1), [Ir (bzq)2 (ipbc)](PF6 ) (2) and [Ir (piq)2 (ipbc)](PF6 ) (3) were designed and synthesized. All the complexes were tested for anticancer activity using 3-(4,5-dimethylthiazole)-2,5-diphenyltetraazolium bromide (MTT) method. The complexes show no cytotoxic activity toward cancer BEL-7402, SGC-7901, Eca-109, A549, HeLa and HepG2 cells. However, upon irradiation with white light, the complexes display high cytotoxicity against BEL-7402 cells with an IC50 value of 5...
April 7, 2018: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29656151/total-hospital-costs-thc-and-length-of-stay-los-of-endovascular-coiling-versus-neurosurgical-clipping-for-unruptured-intracranial-aneurysms-a-systematic-review-and-meta-analysis
#9
REVIEW
Xiaoxi Zhang, Haishuang Tang, Qinghai Huang, Bo Hong, Yi Xu, Jianmin Liu
OBJECTIVE: Comparison of feasibility and safety between endovascular coiling versus neurosurgical clipping for the management of unruptured intracranial aneurysms (UIA) has been incrementally reported. However, economic comparison has been rarely reported. This meta analysis aims at qualitatively and quantitatively analyzing the difference of hospital costs and length of stay between endovascular versus neurosurgical treatment in UIA. METHODS: MEDLINE, the Cochrane database, EMBASE and Web of Science database were searched for cohort studies describing economic hospital cost or length of stay in patients with UIA...
April 12, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29656079/theory-and-practice-of-using-solvent-paramagnetic-relaxation-enhancement-to-characterize-protein-conformational-dynamics
#10
Zhou Gong, Charles D Schwieters, Chun Tang
Paramagnetic relaxation enhancement (PRE) has been established as a powerful tool in NMR for investigating protein structure and dynamics. The PRE is usually measured with a paramagnetic probe covalently attached at a specific site of an otherwise diamagnetic protein. The present work provides the numerical formulation for probing protein structure and conformational dynamics based on the solvent PRE (sPRE) measurement, using two alternative approaches. An inert paramagnetic cosolute randomly collides with the protein, and the resulting sPRE manifests the relative solvent exposure of protein nuclei...
April 12, 2018: Methods: a Companion to Methods in Enzymology
https://www.readbyqxmd.com/read/29655745/study-of-the-biochemical-formation-pathway-of-aroma-compound-1-phenylethanol-in-tea-camellia-sinensis-l-o-kuntze-flowers-and-other-plants
#11
Ying Zhou, Qiyuan Peng, Lanting Zeng, Jinchi Tang, Jianlong Li, Fang Dong, Ziyin Yang
After tea leaves, tea (Camellia sinensis) flowers are becoming a second tea plant resource because they contain not only functional metabolites similar to those found in tea leaves, but also predominant amounts of functional metabolites that only occur in tea leaves in small amounts. 1-Phenylethanol (1PE) is a predominant aroma compound found in tea flowers. A 1PE synthase in tea flowers was isolated, functionally characterized, and shown to have the highest catalytic efficiency for the conversion of acetophenone (AP)...
August 30, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29655725/n-s-co-doped-carbon-dots-based-fluorescent-on-off-on-sensor-for-determination-of-ascorbic-acid-in-common-fruits
#12
Xueli Luo, Wengang Zhang, Yong Han, Xiumei Chen, Li Zhu, Wenzhi Tang, Jianlong Wang, Tianli Yue, Zhonghong Li
A switchable sensor based on N and S co-doped carbon dots (N,S-CDs) was developed to determine ascorbic acid (AA) content in common fruits via fluorescence quenching of N,S-CDs by Fe3+ (off) and recovery by AA (on). TEM showed that the particle size was 2.35-7.95 nm with an average diameter of 5.12 nm. XPS and FTIR confirmed the presence of -OH, -COOH and -NH2 on N,S-CDs surface. UV-vis and FTIR revealed that the coordination of -COOH and -NH2 on N,S-CDs surface with Fe3+ accounted for FL quenching, and the release of -NH2 from coordination complexes due to the reduction of Fe3+ by AA led to partly FL recovery...
August 30, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29655602/overexpression-of-ctrp3-protects-against-sepsis-induced-myocardial-dysfunction-in-mice
#13
Wen-Ying Wei, Zhen-Guo Ma, Ning Zhang, Si-Chi Xu, Yu-Pei Yuan, Xiao-Feng Zeng, Qi-Zhu Tang
C1q/tumor necrosis factor-related protein-3 (CTRP3) shows striking homologies of genomic structure to the adiponectin. In this study, we aimed to investigate the protective role of CTRP3 against sepsis-induced cardiomyopathy. Here, we overexpressed CTRP3 in myocardium by direct intramyocardial injection and constructed a model of lipopolysaccharide (LPS)-induced sepsis in mice. Our results demonstrated that cardiac-specific overexpression of CTRP3 remarkably attenuated myocardial dysfunction and increased the phosphorylation level of AMPKα during LPS-induced sepsis...
April 12, 2018: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/29655580/canadian-association-of-radiologists-white-paper-on-artificial-intelligence-in-radiology
#14
REVIEW
An Tang, Roger Tam, Alexandre Cadrin-Chênevert, Will Guest, Jaron Chong, Joseph Barfett, Leonid Chepelev, Robyn Cairns, J Ross Mitchell, Mark D Cicero, Manuel Gaudreau Poudrette, Jacob L Jaremko, Caroline Reinhold, Benoit Gallix, Bruce Gray, Raym Geis
Artificial intelligence (AI) is rapidly moving from an experimental phase to an implementation phase in many fields, including medicine. The combination of improved availability of large datasets, increasing computing power, and advances in learning algorithms has created major performance breakthroughs in the development of AI applications. In the last 5 years, AI techniques known as deep learning have delivered rapidly improving performance in image recognition, caption generation, and speech recognition...
April 11, 2018: Canadian Association of Radiologists Journal, Journal L'Association Canadienne des Radiologistes
https://www.readbyqxmd.com/read/29653456/hesperidin-prevents-high-glucose-induced-damage-of-retinal-pigment-epithelial-cells
#15
Wayne Young Liu, Shorong-Shii Liou, Tang-Yao Hong, I-Min Liu
The present study aimed to determine whether hesperidin, a plant-based active flavanone found in citrus fruits, can prevent high glucose-induced retinal pigment epithelial (RPE) cell impairment. Cultured human RPE cells (ARPE-19) were exposed to a normal glucose concentration (5.5 mM) for 4 d and then soaked in either normal (5.5 mM) or high (33.3 mM) concentrations of D-glucose with or without different concentrations of hesperidin (10, 20, or 40 µM) for another 48 h. The survival rates of the cells were measured using a 3-(4,5-dimethyl thiazol-2-yl)-2,5-diphenyl tetrazolium bromide reduction assay...
April 13, 2018: Planta Medica
https://www.readbyqxmd.com/read/29653425/microplastics-and-polycyclic-aromatic-hydrocarbons-pahs-in-xiamen-coastal-areas-implications-for-anthropogenic-impacts
#16
Guowen Tang, Mengyang Liu, Qian Zhou, Haixia He, Kai Chen, Haibo Zhang, Jiahui Hu, Qinghui Huang, Yongming Luo, Hongwei Ke, Bin Chen, Xiangrong Xu, Minggang Cai
Microplastics and polycyclic aromatic hydrocarbons (PAHs) were investigated to study the influence of human activities and to find their possible relationship on the coastal environments, where the coastal areas around Xiamen are undergoing intensive processes of industrialization and urbanization in the southeast China. The abundance of microplastics in Xiamen coastal areas was 103 to 2017particles/m3 in surface seawater and 76 to 333 particles/kg in sediments. Concentrations of dissolved PAHs varied from 18...
April 10, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29653392/electrolyzed-water-and-mild-thermal-processing-of-atlantic-salmon-salmo-salar-reduction-of-listeria-monocytogenes-and-changes-in-protein-structure
#17
Mahmoudreza Ovissipour, Setareh Ghorban Shiroodi, Barbara Rasco, Juming Tang, Shyam S Sablani
This study investigated the effect of different electrolyzed water (EO) solutions, including acidic electrolyzed water (AEW) and neutral electrolyzed water (NEW), alone and in combination with mild thermal processing (50, 55, 60, 65 °C) at different exposure times (2, 6, 10 min) on the reduction of Listeria monocytogenes on Atlantic salmon fillets. The effects of the EO water solutions on cell wall structures of L. monocytogenes and on the secondary structure of salmon protein were studied using Fourier Transform Infra-Red (FTIR) spectroscopy...
April 4, 2018: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/29653288/ph-protective-y-1-receptor-ligand-functionalized-antiphagocytosis-bplp-wpu-micelles-for-enhanced-tumor-imaging-and-therapy-with-prolonged-survival-time
#18
Zhenqi Jiang, Yuchen Tian, Dingying Shan, Yinjie Wang, Ethan Gerhard, Jianbi Xia, Rong Huang, Yan He, Aiguo Li, Jianchao Tang, Huimin Ruan, Yong Li, Juan Li, Jian Yang, Aiguo Wu
Nanoparticle-based tumor therapies are extensively studied; however, few are capable of improving patient survival time due to premature drug leakage, off target effects, and poor tissue penetration. Previously, we successfully synthesized a novel family of Y1 receptor (Y1 R) ligand modified, photoluminescent BPLP nanobubbles and nanoparticles for targeted breast cancer ultrasound imaging; however, increased accumulation could also be observed in the liver, kidney, and spleen, suggesting significant interaction of the particles with macrophages in vivo...
April 4, 2018: Biomaterials
https://www.readbyqxmd.com/read/29653275/safety-and-efficacy-of-flow-diverter-treatment-for-aneurysm-in-small-cerebral-vessels-a-systematic-review-and-meta-analysis
#19
REVIEW
Yazhou Yan, Deyuan Zhu, Haishuang Tang, Qinghai Huang
PURPOSE: To clarify the safety and efficacy of flow diverter (FD) treatment for aneurysm in small cerebral vessels, we conducted a systematic review of the literature analyzing perioperative and long-term clinical and angiographic outcomes. METHODS: A comprehensive review of the up-to-date literature for studies with ≥10 patients related to FD treatment of small vessel aneurysms published was performed. Random-effects meta-analysis was used to pool the following outcomes: complete occlusion, technical procedural success, perioperative mortality, perioperative stroke, procedure-related morbidity and mortality, all complications, long-term mortality, and overall good outcome...
April 10, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29653227/rsrc1-and-cpz-gene-polymorphisms-with-neuroblastoma-susceptibility-in-chinese-children
#20
Jue Tang, Wei Liu, Jinhong Zhu, Jiao Zhang, Feng-Hua Wang, Jiang-Hua Liang, Jia-Hang Zeng, Hui Wang, Huimin Xia, Jing He
Two new neuroblastoma susceptibility loci at 3q25 (RSRC1 rs6441201 G > A) and 4p16 (CPZ rs3796725 T > C and rs3796727 A > G) were identified by a genome-wide association study (GWAS) involving Italians, African Americans and European Americans. In this case-control study with 393 neuroblastoma cases and 812 controls, we investigated the association between these three polymorphisms and neuroblastoma susceptibility in Chinese population. We found that participants harboring the RSRC1 rs6441201A allele were associated with an increased risk of neuroblastoma (AA vs...
April 10, 2018: Gene
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