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https://www.readbyqxmd.com/read/28509720/effects-of-rn-age-and-experience-on-transformational-leadership-practices
#1
Susan Herman, Mary Gish, Ruth Rosenblum, Michael Herman
OBJECTIVE: This study reported the evolution of transformational leadership (TL) practices and behaviors across years of age, management experience, and professional nursing practice within a professional nursing leadership organization. BACKGROUND: Recent studies of CNO TL found valuations peak near age 60 years. This study reported on a wider range of management positions, correlating years of RN practice and management experience and age to TL metrics. METHOD: This study used Kouzes and Posner's Leadership Practices Inventory-Self-Assessment (LPI-S) to survey a nursing leadership organization, the Association of California Nurse Leaders (ACNL)...
May 15, 2017: Journal of Nursing Administration
https://www.readbyqxmd.com/read/28508030/incidental-leiomyosarcoma-found-at-the-time-of-cesarean-hysterectomy-for-morbidly-adherent-placenta
#2
Lauren C Hand, Alexis C Gimovsky, Joanna S Y Chan, Norman G Rosenblum, Christine H Kim
BACKGROUND: Incidental leiomyosarcoma (LMS) is a rare diagnosis in pregnancy or in the puerperium. To our knowledge, this is the first case reported in the literature of incidental LMS after cesarean hysterectomy for morbidly adherent placenta. CASE: We present a case of a cesarean hysterectomy performed for a suspected morbidly adherent placenta in a patient with three prior cesarean deliveries, an anterior placenta previa and a fundal fibroid. Subsequent pathology identified a LMS on final specimen...
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28501288/recurrent-episodes-of-brief-global-amnesia-related-to-intrathecal-baclofen-pump-originally-mistaken-for-psychogenic-nonepileptic-seizures
#3
David Rosenblum, Gulam Noorani, Paul H Desan
No abstract text is available yet for this article.
March 16, 2017: Psychosomatics
https://www.readbyqxmd.com/read/28465541/transcriptional-landscape-of-epithelial-and-immune-cell-populations-revealed-through-facs-seq-of-healthy-human-skin
#4
Richard S Ahn, Keyon Taravati, Kevin Lai, Kristina M Lee, Joanne Nititham, Rashmi Gupta, David S Chang, Sarah T Arron, Michael Rosenblum, Wilson Liao
Human skin consists of multiple cell types, including epithelial, immune, and stromal cells. Transcriptomic analyses have previously been performed from bulk skin samples or from epithelial and immune cells expanded in cell culture. However, transcriptomic analysis of bulk skin tends to drown out expression signals from relatively rare cells while cell culture methods may significantly alter cellular phenotypes and gene expression profiles. To identify distinct transcriptomic profiles of multiple cell populations without substantially altering cell phenotypes, we employed a fluorescence activated cell sorting method to isolate keratinocytes, dendritic cells, CD4+ T effector cells, and CD8+ T effector cells from healthy skin samples, followed by RNA-seq of each cell population...
May 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28463048/calcifying-pseudoneoplasm-of-the-spine-imaging-and-pathological-features
#5
Atin Saha, Julio Arevalo-Perez, Kyung K Peck, Marc Rosenblum, Mark Bilsky, Eric Lis, Sasan Karimi
Calcifying pseudoneoplasms of the neuraxis are extremely rare calcified lesions that can occur anywhere in the central nervous system. These non-neoplastic lesions have been reported to arise both in the brain and spine with similar frequency and can be found intra-axially as well as extra-axially. The associated symptoms are generally due to mass effect rather than local invasion as calcifying pseudoneoplasms of the neuraxis are usually considered to be benign non-infiltrative lesions. We report a unique case of a 67-year-old male patient who developed lower extremity weakness and gait instability with imaging and histological features of calcifying pseudoneoplasm of the neuraxis occurring in the spine with adhesive features and intradural extension...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/28457715/feeding-and-mealtime-correlates-of-maternal-concern-about-children-s-weight
#6
Jacqueline M Branch, Danielle P Appugliese, Katherine L Rosenblum, Alison L Miller, Julie C Lumeng, Katherine W Bauer
OBJECTIVE: To examine associations between maternal concern regarding their children becoming overweight and two domains of weight-related parenting; child feeding practices and family meal characteristics. DESIGN: Cross-sectional study. PARTICIPANTS: Low-income mothers (n = 264; 67% non-Hispanic white) and their children (51.5% male, aged 4.02-8.06 years). VARIABLES MEASURED: Maternal concern and feeding practices, using the Child Feeding Questionnaire...
April 28, 2017: Journal of Nutrition Education and Behavior
https://www.readbyqxmd.com/read/28449526/recurrent-aortic-dissection-a-challenging-but-rare-dilemma
#7
EDITORIAL
Joshua M Rosenblum, Edward P Chen
No abstract text is available yet for this article.
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28448913/temporal-characterization-of-flowback-and-produced-water-quality-from-a-hydraulically-fractured-oil-and-gas-well
#8
James Rosenblum, Andrew W Nelson, Bridger Ruyle, Michael K Schultz, Joseph N Ryan, Karl G Linden
This study examined water quality, naturally-occurring radioactive materials (NORM), major ions, trace metals, and well flow data for water used and produced from start-up to operation of an oil and gas producing hydraulically-fractured well (horizontal) in the Denver-Julesburg (DJ) Basin in northeastern Colorado. Analysis was conducted on the groundwater used to make the fracturing fluid, the fracturing fluid itself, and nine flowback/produced water samples over 220days of operation. The chemical oxygen demand of the wastewater produced during operation decreased from 8200 to 2500mg/L, while the total dissolved solids (TDS) increased in this same period from 14,200 to roughly 19,000mg/L...
April 24, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28442493/characteristics-and-outcomes-of-canadian-md-phd-program-graduates-a-cross-sectional-survey
#9
Michael A Skinnider, Jordan W Squair, David D W Twa, Jennifer X Ji, Alexandra Kuzyk, Xin Wang, Patrick E Steadman, Kirill Zaslavsky, Ayan K Dey, Mark J Eisenberg, Ève-Reine Gagné, Kent T HayGlass, James F Lewis, Peter J Margetts, D Alan Underhill, Norman D Rosenblum, Lynn A Raymond
BACKGROUND: Combined MD/PhD programs provide a structured path for physician-scientist training, but assessment of their success within Canada is limited by a lack of quantitative data. We collected outcomes data for graduates of Canadian MD/PhD programs. METHODS: We developed and implemented a Web-based survey consisting of 41 questions designed to collect outcomes data for Canadian MD/PhD program alumni from 8 Canadian universities who had graduated before September 2015...
April 25, 2017: CMAJ Open
https://www.readbyqxmd.com/read/28435520/genetically-transforming-human-osteoblasts-to-sarcoma-development-of-an-osteosarcoma-model
#10
Yi Yang, Rui Yang, Michael Roth, Sajida Piperdi, Wendong Zhang, Howard Dorfman, Pulivarthi Rao, Amy Park, Sandeep Tripathi, Carrie Freeman, Yunjia Zhang, Rebecca Sowers, Jeremy Rosenblum, David Geller, Bang Hoang, Jonathan Gill, Richard Gorlick
Osteosarcoma is the most common primary malignant bone tumor in children and young adults. Although histologically defined by the presence of malignant osteoid, the tumor possesses lineage multipotency suggesting it could be derived from a cell anywhere on the differentiation pathway between a mesenchymal stem cell (MSC) and a mature osteoblast. To determine if preosteoblasts (pOB) could be the cell of origin differentiated MSCs were transformed with defined genetic elements. MSCs and pOB differentiated from the same MSCs were serially transformed with the oncogenes hTERT, SV40 large T antigen and H-Ras...
January 2017: Genes & Cancer
https://www.readbyqxmd.com/read/28432038/seeking-web-based-information-about-attention-deficit-hyperactivity-disorder-where-what-and-when
#11
Sara Rosenblum, Elad Yom-Tov
BACKGROUND: Attention Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder, prevalent among 2-10% of the population. OBJECTIVE: The objective of this study was to describe where, what, and when people search online for topics related to ADHD. METHODS: Data were collected from Microsoft's Bing search engine and from the community question and answer site, Yahoo Answers. The questions were analyzed based on keywords and using further statistical methods...
April 21, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28424893/diversity-in-growth-patterns-among-strains-of-the-lethal-fungal-pathogen-batrachochytrium-dendrobatidis-across-extended-thermal-optima
#12
Jamie Voyles, Leah R Johnson, Jason Rohr, Rochelle Kelly, Carley Barron, Delaney Miller, Josh Minster, Erica Bree Rosenblum
The thermal sensitivities of organisms regulate a wide range of ecological interactions, including host-parasite dynamics. The effect of temperature on disease ecology can be remarkably complex in disease systems where the hosts are ectothermic and where thermal conditions constrain pathogen reproductive rates. Amphibian chytridiomycosis, caused by the pathogen Batrachochytrium dendrobatidis (Bd), is a lethal fungal disease that is influenced by temperature. However, recent temperature studies have produced contradictory findings, suggesting that our current understanding of thermal effects on Bd may be incomplete...
April 19, 2017: Oecologia
https://www.readbyqxmd.com/read/28412898/a-collaborative-process-for-evaluating-infant-mental-health-home-visiting-in-michigan
#13
Jamie M Lawler, Katherine L Rosenblum, Maria Muzik, Mary Ludtke, Deborah J Weatherston, Betty Tableman
This column describes an innovative collaboration in Michigan that could serve as a model for meaningful community-university-state partnerships. Recent legislation in Michigan threatened the infant mental health home visiting program, a service for Medicaid-eligible infants, toddlers, and families affected by mental illness. The University of Michigan is overseeing two major studies in collaboration with the Michigan Department of Health and Human Services, the Michigan Association for Infant Mental Health, the Michigan Infant Toddler Research Exchange faculty network, and community health service providers to determine the evidence base for the program and ensure its future success...
April 17, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/28411193/liver-metastasis-and-treatment-outcome-with-anti-pd-1-monoclonal-antibody-in-patients-with-melanoma-and-nsclc
#14
Paul C Tumeh, Matthew D Hellmann, Omid Hamid, Katy K Tsai, Kimberly L Loo, Matthew A Gubens, Michael Rosenblum, Christina L Harview, Janis M Taube, Nathan Handley, Neharika Khurana, Adi Nosrati, Matthew F Krummel, Andrew Tucker, Eduardo V Sosa, Phillip J Sanchez, Nooriel Banayan, Juan C Osorio, Dan L Nguyen-Kim, Jeremy Chang, I Peter Shintaku, Peter D Boasberg, Emma J Taylor, Pamela N Munster, Alain P Algazi, Bartosz Chmielowski, Reinhard Dummer, Tristan R Grogan, David Elashoff, Jimmy Hwang, Simone M Goldinger, Edward B Garon, Robert H Pierce, Adil Daud
We explored the association between liver metastases, tumor CD8(+) T-cell count, and response in patients with melanoma or lung cancer treated with the anti-PD-1 antibody, pembrolizumab. The melanoma discovery cohort was drawn from the phase I Keynote 001 trial, whereas the melanoma validation cohort was drawn from Keynote 002, 006, and EAP trials and the non-small cell lung cancer (NSCLC) cohort from Keynote 001. Liver metastasis was associated with reduced response and shortened progression-free survival [PFS; objective response rate (ORR), 30...
April 14, 2017: Cancer Immunology Research
https://www.readbyqxmd.com/read/28409434/the-sgim-teach-program-a-curriculum-for-teachers-of-clinical-medicine
#15
Christopher L Knight, Donna M Windish, Steven A Haist, Reena Karani, Shobhina Chheda, Michael Rosenblum, Preetha Basaviah, Abby L Spencer, Eva M Aagaard
BACKGROUND: Demand for faculty with teaching expertise is increasing as medical education is becoming well established as a career pathway. Junior faculty may be expected to take on teaching responsibilities with minimal training in teaching skills. AIM: To address the faculty development needs of junior clinician-educators with teaching responsibilities and those changing their career focus to include teaching. SETTING: Sessions at two Society of General Internal Medicine (SGIM) annual meetings combined with local coaching and online learning during the intervening year...
April 13, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28409347/origin-and-function-of-the-renal-stroma-in-health-and-disease
#16
Christopher J Rowan, Sepideh Sheybani-Deloui, Norman D Rosenblum
The renal stroma is defined as a heterogeneous population of cells that serve both as a supportive framework and as a source of specialized cells in the renal capsule, glomerulus, vasculature, and interstitium. In this chapter, we review published evidence defining what, where, and why stromal cells are important. We describe the functions of the renal stroma andhow stromal derivatives are crucial for normal kidney function. Next, we review the specification of stromal cells from the Osr1+ intermediate mesoderm and T+ presomitic mesoderm during embryogenesis and stromal cell differentiation...
2017: Results and Problems in Cell Differentiation
https://www.readbyqxmd.com/read/28401845/parent-child-intervention-decreases-stress-and-increases-maternal-brain-activity-and-connectivity-during-own-baby-cry-an-exploratory-study
#17
James E Swain, S Shaun Ho, Katherine L Rosenblum, Diana Morelen, Carolyn J Dayton, Maria Muzik
Parental responses to their children are crucially influenced by stress. However, brain-based mechanistic understanding of the adverse effects of parenting stress and benefits of therapeutic interventions is lacking. We studied maternal brain responses to salient child signals as a function of Mom Power (MP), an attachment-based parenting intervention established to decrease maternal distress. Twenty-nine mothers underwent two functional magnetic resonance imaging brain scans during a baby-cry task designed to solicit maternal responses to child's or self's distress signals...
May 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28401766/occurrence-and-in-vitro-bioactivity-of-estrogen-androgen-and-glucocorticoid-compounds-in-a-nationwide-screen-of-united-states-stream-waters
#18
Justin M Conley, Nicola Evans, Mary C Cardon, Laura Rosenblum, Luke R Iwanowicz, Phillip C Hartig, Kathleen M Schenck, Paul M Bradley, Vickie S Wilson
In vitro bioassays are sensitive, effect-based tools used to quantitatively screen for chemicals with nuclear receptor activity in environmental samples. We measured in vitro estrogen (ER), androgen (AR), and glucocorticoid receptor (GR) activity, along with a broad suite of chemical analytes, in streamwater from 35 well-characterized sites (3 reference and 32 impacted) across 24 states and Puerto Rico. ER agonism was the most frequently detected with nearly all sites (34/35) displaying activity (range, 0.054-116 ng E2Eq L(-1))...
April 12, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28395084/the-utility-of-expert-diagnosis-in-surgical-neuropathology-analysis-of-consultations-reviewed-at-5-national-comprehensive-cancer-network-institutions
#19
Janet M Bruner, David N Louis, Roger McLendon, Marc K Rosenblum, W Tad Archambault, Susan Most, Tarik Tihan
The aim of this study was to characterize the type and degree of discrepancies between non-expert and expert diagnoses of CNS tumors to identify the value of consultations in surgical neuropathology. Neuropathology experts from 5 National Comprehensive Cancer Network (NCCN) member institutions participated in the review of 1281 consultations selected based on inclusion criteria. The consultation cases were re-reviewed at the NCCN headquarters to determine concordance with the original diagnoses. Among all consultations, 249 (19...
March 1, 2017: Journal of Neuropathology and Experimental Neurology
https://www.readbyqxmd.com/read/28393139/effects-of-acute-confinement-stress-induced-hypothalamic-pituitary-adrenal-axis-activation-and-concomitant-peripheral-and-central-transforming-growth-factor-%C3%AE-1-measures-in-nonhuman-primates
#20
Jeremy D Coplan, Srinath Gopinath, Chadi G Abdallah, Jeffrey Margolis, Wei Chen, Bruce A Scharf, Leonard A Rosenblum, Olcay A Batuman, Eric L P Smith
Transforming growth factor-β1 (TGF-β1) is a multifunctional cytokine with anti-inflammatory, immunosuppressive and neuroprotective properties. The hypothalamic-pituitary-adrenal (HPA) axis and immune system exert bidirectional influences on each other, via cortisol and TGF-β1, but the exact nature of the interaction is not well characterized. The current study examined the effects, in bonnet macaques (Macaca radiata), of two consecutive acute confinement stress periods in an unfamiliar room while mildly restrained, first without and then with dexamethasone pretreatment (0...
February 2017: Chronic Stress (Thousand Oaks)
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