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https://www.readbyqxmd.com/read/28330718/adult-glucocorticoid-receptor-mrna-expression-volatility-in-response-to-an-acute-stressor-and-juvenile-csf-corticotropin-releasing-factor-a-pilot-neurodevelopmental-study
#1
Shariful A Syed, Eric L P Smith, Olcay Batuman, Leonard A Rosenblum, Michael J Owens, Charles B Nemeroff, Jeremy D Coplan
INTRODUCTION: Early life stress (ELS) has been shown to play a role in establishing persistent maladaptive HPA axis modifications that may contribute to the pathogenesis of mood and anxiety disorders. Central glucocorticoid receptor (GR) messenger RNA (mRNA) expression may facilitate (mal)adaptive responsivity to ELS. The role of adult monocytic GR mRNA expression, a putative CNS proxy, during acute stress exposure was explored as well as the ELS marker, juvenile cerebrospinal fluid (CSF) corticotropin-releasing factor...
March 19, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28329454/adult-congenital-cardiac-care
#2
Brian E Kogon, Kati Miller, Paula Miller, Bahaaldin Alsoufi, Joshua M Rosenblum
BACKGROUND: The Adult Congenital Heart Association (ACHA) is dedicated to supporting patients with congenital heart disease. To guide patients to qualified providers and programs, it maintains a publicly accessible directory of dedicated adult congenital cardiac programs. We analyzed the directory in 2006 and 2015, aiming to evaluate the growth of the directory as a whole and to evaluate the growth of individual programs within the directory. We also hope this raises awareness of the growing opportunities that exist in adult congenital cardiology and cardiac surgery...
March 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28323079/factors-driving-live-discharge-from-hospice-provider-perspectives
#3
Rachel Dolin, Laura C Hanson, Sarah Rosenblum, Sally Stearns, Mark Holmes, Pam Silberman
CONTEXT: The proportion of patients disenrolling from hospice prior to death has increased over the decade with significant variations across hospice types and regions. Such trends have raised concerns about live disenrollment's effect on care quality. Live disenrollment may be driven by factors other than patient preference and may create discontinuities in care, disrupting ongoing patient-provider relationships. Researchers have not explored when and how providers make this decision with patients...
March 16, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28319570/microcystic-elongated-and-fragmented-pattern-invasion-in-ovarian-endometrioid-carcinoma-immunohistochemical-profile-and-prognostic-implications
#4
Allison Goldberg, Lauren Hand, Dan DeCotiis, Norman Rosenblum, Joanna Chan
Microcystic, elongated, and fragmented (MELF) pattern invasion is a poor prognostic indicator in uterine endometrioid carcinoma, but its existence, biology, and prognostic value have not been described in ovarian endometrioid carcinoma. We evaluated cases of ovarian endometrioid carcinoma without synchronous uterine endometrioid carcinoma for MELF and other histologic features. To evaluate tumor biology, we assessed an immunohistochemical profile, including MLH1, PMS2, MSH2, MSH6, β-catenin, e-cadherin, CK19, and cyclin D1...
March 17, 2017: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/28296524/challenges-to-opioid-treatment-programs-after-hurricane-sandy-patient-and-provider-perspectives-on-preparation-impact-and-recovery
#5
Harlan Matusow, Ellen Benoit, Luther Elliott, Eloise Dunlap, Andrew Rosenblum
Over 300,000 patients with an opioid use disorder (OUD) receive methadone maintenance therapy from opioid treatment programs (OTPs) in the United States. Large numbers of these attend OTPs located in New York and New Jersey, areas (largely but not exclusively coastal) impacted by Hurricane Sandy (Sandy) on October 29th, 2012. Disruption of methadone dispensing and other services can have severe consequences to patients (and treatment seekers) such as relapse, dropping out of treatment and resumption or increase in HIV/HCV injection risk behaviors...
March 15, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28284835/randomized-trial-of-a-peer-led-telephone-based-empowerment-intervention-for-persons-with-chronic-spinal-cord-injury-improves-health-self-management
#6
Bethlyn Vergo Houlihan, Miriam Brody, Sarah Everhart-Skeels, Diana Pernigotti, Sam Burnett, Judi Zazula, Christa Green, Stathis Hasiotis, Timothy Belliveau, Subramani Seetharama, David Rosenblum, Alan Jette
OBJECTIVE: To evaluate the impact of "My Care My Call" (MCMC), a peer-led, telephone-based health self-management intervention in adults with chronic spinal cord injury (SCI). DESIGN: Single-blinded randomized controlled trial SETTING: General community PARTICIPANTS: Convenience sample of 84 adults with SCI (X= 9.9 years post-SCI); X=46 years old; 73.8% male; 44% with paraplegia; and 58% White. INTERVENTIONS: Trained Peer Health Coaches (PHC) applied the person-centered health self-management intervention with 42 experimental subjects over 6 months on a tapered call schedule...
March 8, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28276158/an-adolescent-with-large-cell-calcifying-sertoli-cell-tumor-of-the-testis-and-undiagnosed-carney-complex-a-case-report
#7
Frida Rosenblum, Richard Gabriel Koenig, Fady M Mikhail, John R Porterfield, Jeffrey W Nix, Isam-Eldin A Eltoum
Carney Complex (CNC) is a rare autosomal dominant condition with characteristic clinical presentation, tumor development, and unique genetic mutation. We present a unique case and literature review of CNC in which two neoplasms characteristic of this complex were initially diagnosed through cytological fine needle aspirate specimens, leading to the identification of CNC, with subsequent surgical and cytogenetic confirmation. Diagn. Cytopathol. 2017. © 2017 Wiley Periodicals, Inc.
March 9, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28273588/associations-between-stress-biology-indicators-and-overweight-across-toddlerhood
#8
Alison L Miller, Niko Kaciroti, Julie Sturza, Lauren Retzloff, Katherine Rosenblum, Delia M Vazquez, Julie C Lumeng
Biological stress responses are proposed as a pathway through which stress exposure can "get under the skin" and lead to health problems, specifically obesity. Yet, it is not clear when such associations may emerge or whether they are bidirectional. Cortisol and salivary alpha amylase (sAA) were considered indicators of the biological stress response. We tested the longitudinal association between cortisol and sAA and weight in 215 low-income children at ages 21, 27, and 33 months (52% male; 46% non-Hispanic white)...
February 20, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28273176/pulsatile-desynchronizing-delayed-feedback-for-closed-loop-deep-brain-stimulation
#9
Oleksandr V Popovych, Borys Lysyansky, Michael Rosenblum, Arkady Pikovsky, Peter A Tass
High-frequency (HF) deep brain stimulation (DBS) is the gold standard for the treatment of medically refractory movement disorders like Parkinson's disease, essential tremor, and dystonia, with a significant potential for application to other neurological diseases. The standard setup of HF DBS utilizes an open-loop stimulation protocol, where a permanent HF electrical pulse train is administered to the brain target areas irrespectively of the ongoing neuronal dynamics. Recent experimental and clinical studies demonstrate that a closed-loop, adaptive DBS might be superior to the open-loop setup...
2017: PloS One
https://www.readbyqxmd.com/read/28270335/web-delivered-cbt-reduces-heavy-drinking-in-oef-oif-veterans-in-primary-care-with-symptomatic-substance-use-and-ptsd
#10
Michelle C Acosta, Kyle Possemato, Stephen A Maisto, Lisa A Marsch, Kimberly Barrie, Larry Lantinga, Chunki Fong, Haiyi Xie, Michael Grabinski, Andrew Rosenblum
Veterans from conflicts such as the wars in Iraq and Afghanistan commonly return with behavioral health problems, including posttraumatic stress disorder (PTSD) and hazardous or harmful substance use. Unfortunately, many veterans experience significant barriers to receiving evidence-based treatment, including poor treatment motivation, concerns about stigma, and lack of access to appropriate care. To address this need, the current study developed and evaluated a web-based self-management intervention based on cognitive behavioral therapy (CBT), targeting PTSD symptoms and hazardous substance use in a group of symptomatic combat veterans enrolled in VA primary care...
March 2017: Behavior Therapy
https://www.readbyqxmd.com/read/28256369/anti-hu-paraneoplastic-brainstem-encephalitis-caused-by-a-pancreatic-neuroendocrine-tumor-presenting-with-central-hypoventilation
#11
Marc Najjar, Andrew Taylor, Surbhi Agrawal, Tito Fojo, Alexander E Merkler, Marc K Rosenblum, Laura Lennihan, Michael D Kluger
Paraneoplastic neurological syndromes are rare autoimmune manifestations of malignancies associated with specific antibodies. Anti-Hu associated brainstem encephalitis, a well-described syndrome, usually presents subacutely with preferential involvement of the medulla. Anti-Hu antibodies target intraneuronal antigens and are therefore highly correlated with neurological syndromes when present concomitantly with a neoplasm. Reported is a case of anti-Hu brainstem encephalitis associated with a pancreatic neuroendocrine tumor (PNET) presenting with central hypoventilation...
February 27, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28222181/correction-genomic-and-clinical-effects-associated-with-a-relaxation-response-mind-body-intervention-in-patients-with-irritable-bowel-syndrome-and-inflammatory-bowel-disease
#12
Braden Kuo, Manoj Bhasin, Jolene Jacquart, Matthew A Scult, Lauren Slipp, Eric Isaac Kagan Riklin, Veronique Lepoutre, Nicole Comosa, Beth-Ann Norton, Allison Dassatti, Jessica Rosenblum, Andrea H Thurler, Brian C Surjanhata, Nicole N Hasheminejad, Leslee Kagan, Ellen Slawsby, Sowmya R Rao, Eric A Macklin, Gregory L Fricchione, Herbert Benson, Towia A Libermann, Joshua Korzenik, John W Denninger
[This corrects the article DOI: 10.1371/journal.pone.0123861.].
2017: PloS One
https://www.readbyqxmd.com/read/28212827/longitudinal-associations-between-maternal-feeding-and-overweight-in-low-income-toddlers
#13
Julie C Lumeng, Niko Kaciroti, Lauren Retzloff, Katherine Rosenblum, Alison L Miller
Maternal feeding is a frequent intervention target for the prevention of early childhood obesity but longitudinal associations between feeding and child overweight are poorly understood. This observational cohort study sought to examine the cross-lagged associations between maternal feeding and overweight across ages 21, 27, and 33 months. Feeding was measured by maternal self-report (n = 222) at each age. Child weight and length were measured. Cross-lagged analysis was used to evaluate longitudinal associations between feeding and overweight, adjusting for infant birth weight, maternal body mass index, maternal education, and maternal depressive symptoms...
February 15, 2017: Appetite
https://www.readbyqxmd.com/read/28199383/correction-identification-of-a-tumor-specific-active-site-mutation-in-casein-kinase-1%C3%AE-by-chemical-proteomics
#14
Eric S Okerberg, Anna Hainley, Heidi Brown, Arwin Aban, Senait Alemayehu, Ann Shih, Jane Wu, Matthew P Patricelli, John W Kozarich, Tyzoon Nomanbhoy, Jonathan S Rosenblum
[This corrects the article DOI: 10.1371/journal.pone.0152934.].
2017: PloS One
https://www.readbyqxmd.com/read/28196033/thromboembolic-disease-in-patients-with-metastatic-femoral-lesions-a-comparison-between-prophylactic-fixation-and-fracture-fixation
#15
Arun Aneja, Jimmy J Jiang, Anna Cohen-Rosenblum, Hue L Luu, Terrance D Peabody, Samer Attar, T David Luo, Rex C Haydon
BACKGROUND: We are not aware of any previous studies that have compared the rate of venous thromboembolic events in patients who underwent prophylactic intramedullary nailing because of an impending fracture with the rate in patients who underwent intramedullary nailing after a pathological fracture. The objective of the present study was to determine if the rate of venous thromboembolic events varies between patients who are managed with prophylactic fixation and those who are managed with fixation after a pathological fracture...
February 15, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28183197/the-relationship-between-sensory-processing-patterns-and-occupational-engagement-among-older-persons
#16
Batya Engel-Yeger, Sara Rosenblum
BACKGROUND: Meaningful occupational engagement is essential for successful aging. Sensory-processing abilities that are known to deteriorate with age may reduce occupational engagement. However, the relationship between sensory-processing abilities and occupational engagement among older persons in daily life is unknown. PURPOSE: This study examined the relationship between sensory-processing patterns and occupational engagement among older persons. METHOD: Participants were 180 people, ages 50 to 73 years, in good health, who lived in their homes...
January 1, 2017: Canadian Journal of Occupational Therapy. Revue Canadienne D'ergothérapie
https://www.readbyqxmd.com/read/28174037/observed-infant-food-cue-responsivity-associations-with-maternal-report-of-infant-eating-behavior-breastfeeding-and-infant-weight-gain
#17
Elizabeth Buvinger, Katherine Rosenblum, Alison L Miller, Niko A Kaciroti, Julie C Lumeng
Infant obesity and the rate of weight gain during infancy are significant public health concerns, but few studies have examined eating behaviors in infancy. Food cue responsivity has been described as a key contributor to obesity risk in school age children and adults, but has been rarely examined during infancy. The purpose of the current study was to test among 30 infants aged 6-12 months the hypotheses that infants would show greater interest in food versus non-food stimuli, and that greater birth weight, greater rate of weight gain during infancy, greater mother-reported food responsiveness, being formula versus breastmilk fed, and higher maternal body mass index, would each be associated with greater interest in the food versus non-food stimulus...
May 1, 2017: Appetite
https://www.readbyqxmd.com/read/28172738/p721-a-switch-in-the-prevalence-ratio-of-crohn-s-disease-vs-ulcerative-colitis-in-israel-between-2003-and-2015-a-report-from-the-epi-iirn-group
#18
M Friedman, S Odes, R Balicer, M Hoshen, D Cohen, J Rosenblum, N Zigman, I Goren, N Lederman, E Matz, D Dushnitzky, N Borovsky, M Gavish, G Focht, M Avitzour, R Axelrod, Y Chowers, R Eliakim, S Ben-Horin, I Dotan, E Israeli, Z Levy, E Benchimol, D Turner
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28172622/p689-biologics-utilization-in-children-with-inflammatory-bowel-diseases-is-higher-and-earlier-than-in-adults-a-report-from-the-epi-iirn-group
#19
M Friedman, R Axelrod, J Rosenblum, N Zigman, I Goren, N Lederman, N Cohen, E Matz, D Dushnitzky, N Borovsky, M Gavish, G Focht, M Avitzour, I Dotan, E Benchimol, D Turner
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28162334/-532-patients-experiences-with-web-based-cbt-for-the-treatment-of-chronic-pain-using-qualitative-research-to-deepen-understanding-of-intervention-effects
#20
S Moore, H Guarino, A Rosenblum, L Marsch
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
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