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https://www.readbyqxmd.com/read/28231282/mindboggling-morphometry-of-human-brains
#1
Arno Klein, Satrajit S Ghosh, Forrest S Bao, Joachim Giard, Yrjö Häme, Eliezer Stavsky, Noah Lee, Brian Rossa, Martin Reuter, Elias Chaibub Neto, Anisha Keshavan
Mindboggle (http://mindboggle.info) is an open source brain morphometry platform that takes in preprocessed T1-weighted MRI data and outputs volume, surface, and tabular data containing label, feature, and shape information for further analysis. In this article, we document the software and demonstrate its use in studies of shape variation in healthy and diseased humans. The number of different shape measures and the size of the populations make this the largest and most detailed shape analysis of human brains ever conducted...
February 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28226060/nonpharmacological-interventions-to-improve-quality-of-life-in-heart-failure-an-integrative-review
#2
Daniela Reuter do Amaral, Marina Bertelli Rossi, Camila Takao Lopes, Juliana de Lima Lopes
Objective: to identify articles that assessed the effectiveness or efficacy of nonpharmacological interventions to improve quality of life of people with heart failure in the literature. Method: an integrative literature review was performed in Lilacs, MedLine and SciELO databases, including randomized or nonrandomized clinical trials and quasi-experimental studies published between 2003 and 2014, in Portuguese, English or Spanish. Results: twenty-three studies were included...
January 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28225484/association-between-erbb4-single-nucleotide-polymorphisms-and-susceptibility-to-schizophrenia-a-meta-analysis-of-case-control-studies
#3
Yanguo Feng, Dejun Cheng, Chaofeng Zhang, Yuchun Li, Zhiying Zhang, Juan Wang, Xiao Feng
BACKGROUND: Accumulating studies have reported inconsistent association between ErbB4 single nucleotide polymorphisms (SNPs) and predisposition to schizophrenia. To better interpret this issue, here we conducted a meta-analysis using published case-control studies. METHODS: We conducted a systematic search of MEDLINE (Pubmed), Embase (Ovid), Web of Science (Thomson-Reuters) to identify relevant references. The association between ErbB4 SNPs and schizophrenia was assessed by odds ratios (ORs) and 95% confidence intervals (CIs)...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28223187/deepnat-deep-convolutional-neural-network-for-segmenting-neuroanatomy
#4
Christian Wachinger, Martin Reuter, Tassilo Klein
We introduce DeepNAT, a 3D Deep convolutional neural network for the automatic segmentation of NeuroAnaTomy in T1-weighted magnetic resonance images. DeepNAT is an end-to-end learning-based approach to brain segmentation that jointly learns an abstract feature representation and a multi-class classification. We propose a 3D patch-based approach, where we do not only predict the center voxel of the patch but also neighbors, which is formulated as multi-task learning. To address a class imbalance problem, we arrange two networks hierarchically, where the first one separates foreground from background, and the second one identifies 25 brain structures on the foreground...
February 18, 2017: NeuroImage
https://www.readbyqxmd.com/read/28222136/cardiac-strength-interval-curves-calculated-using-a-bidomain-tissue-with-a-parsimonious-ionic-current
#5
Suran K Galappaththige, Richard A Gray, Bradley J Roth
The strength-interval curve plays a major role in understanding how cardiac tissue responds to an electrical stimulus. This complex behavior has been studied previously using the bidomain formulation incorporating the Beeler-Reuter and Luo-Rudy dynamic ionic current models. The complexity of these models renders the interpretation and extrapolation of simulation results problematic. Here we utilize a recently developed parsimonious ionic current model with only two currents-a sodium current that activates rapidly upon depolarization INa and a time-independent inwardly rectifying repolarization current IK-which reproduces many experimentally measured action potential waveforms...
2017: PloS One
https://www.readbyqxmd.com/read/28218491/a-new-class-of-lasing-materials-intrinsic-stimulated-emission-from-nonlinear-optically-active-metal-organic-frameworks
#6
Raghavender Medishetty, Venkatram Nalla, Lydia Nemec, Sebastian Henke, David Mayer, Handong Sun, Karsten Reuter, Roland A Fischer
Blue-color stimulated emission with low threshold power is observed from In- and Zn-MOFs, which feature a highly fluorescent chromophore densely packed and rigidly linked to the metal-ion centers in the solid state. The density-of-states and transition dipole moments are calculated and the stimulated emission phenomenon is correlated with these properties.
February 20, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28213906/impact-of-dexamethasone-in-patients-with-aneurysmal-subarachnoid-haemorrhage
#7
P Czorlich, T Sauvigny, F Ricklefs, T Abboud, A Nierhaus, E Vettorazzi, D A Reuter, J Regelsberger, M Westphal, N O Schmidt
BACKGROUND AND PURPOSE: The role of corticosteroids in the treatment of patients with aneurysmal subarachnoid haemorrhage (SAH) has remained controversial for decades. Recent studies have suggested that the administration of corticosteroids in SAH patients is associated with favourable outcomes. Given their significant adverse effects, it is essential to identify those patients who will benefit from treatment with corticosteroids. METHODS: A retrospective analysis of a prospectively collected cohort (n = 306) with SAH who were treated by microsurgical clipping or endovascular intervention was performed...
February 17, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28212446/evaluation-of-university-scientific-research-ability-based-on-the-output-of-sci-tech-papers-a-d-ahp-approach
#8
Fan Zong, Lifang Wang
University scientific research ability is an important indicator to express the strength of universities. In this paper, the evaluation of university scientific research ability is investigated based on the output of sci-tech papers. Four university alliances from North America, UK, Australia, and China, are selected as the case study of the university scientific research evaluation. Data coming from Thomson Reuters InCites are collected to support the evaluation. The work has contributed new framework to the issue of university scientific research ability evaluation...
2017: PloS One
https://www.readbyqxmd.com/read/28196861/molecular-determinants-of-the-n-terminal-acetyltransferase-naa60-anchoring-to-the-golgi-membrane
#9
Henriette Aksnes, Marianne Goris, Øyvind Strømland, Adrian Drazic, Qaiser Waheed, Nathalie Reuter, Thomas Arnesen
Nα-acetyltransferase 60 (Naa60 or NatF) was recently identified as an unconventional N-terminal acetyltransferase (NAT) since it localizes to organelles, in particular the Golgi apparatus, and has a preference for acetylating N-termini of transmembrane proteins. This knowledge challenged the prevailing view of N-terminal acetylation as a co-translational ribosome-associated process and suggested a new mechanistic functioning for the enzymes responsible for this increasingly recognized protein modification...
February 14, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28192169/the-serotonin-transporter-polymorphism-5-httlpr-and-coping-strategies-influence-successful-emotion-regulation-in-an-acute-stress-situation-physiological-evidence
#10
Thomas Plieger, Martin Melchers, Annabel Vetterlein, Janina Görtz, Sarah Kuhn, Melissa Ruppel, Martin Reuter
INTRODUCTION: Emotion regulation is an important everyday-life skill to reduce harm and stress. Consequently, research shows associations between psychopathologies and emotional dysregulation. The serotonin transporter polymorphism (5-HTTLPR) has repeatedly been associated to phenotypes and syndromes related to emotional dysregulation. However, there is no study showing any direct effects of 5-HTTLPR genotype and emotion regulation. Hence, the aim of the present study was to draw a link between 5-HTTLPR to emotion regulation...
February 9, 2017: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/28190672/-bibliometric-analysis-of-iberpoc-and-epi-scan-studies-contribution-of-the-smoking-variable-on-the-iberpoc-study
#11
J I de Granda-Orive, A Alonso-Arroyo, D López-Padilla, G Segrelles-Calvo, C A Jiménez-Ruiz, S Solano-Reina
OBJECTIVES: The aim of this study was to perform a bibliometric analysis of EPI-SCAN and IBERPOC studies using the Science Citation Index and Scopus databases, and to determine the overall impact with the impact of smoking on IBERPOC as a secondary objective. METHOD: A general searching was conducted in Science Citation Index-Expanded through the Web of Science (WoS) (Thomson Reuters) platform and Scopus on 23 March 2015. The search strategy included the terms "iberpoc" OR "episcan" was performed on 15 October 2015...
February 9, 2017: Semergen
https://www.readbyqxmd.com/read/28188746/context-dependent-epigenetic-regulation-of-nuclear-factor-of-activated-t-cells-1-in-pancreatic-plasticity
#12
Nai-Ming Chen, Albrecht Neesse, Moritz Lino Dyck, Benjamin Steuber, Alexander O Koenig, Clara Lubeseder-Martellato, Thore Winter, Teresa Forster, Hanibal Bohnenberger, Julia Kitz, Kirsten-Reuter Jessen, Heidi Griesmann, Jochen Gaedcke, Marian Grade, Jin-San Zhang, Wan-Chi Tsai, Jens Siveke, Hans-Ulrich Schildhaus, Philipp Ströbel, Steven A Johnsen, Volker Ellenrieder, Elisabeth Hessmann
BACKGROUND & AIMS: The ability of exocrine pancreatic cells to change the cellular phenotype is required for tissue regeneration upon injury but also contributes to their malignant transformation and tumor progression. We investigated context-dependent signaling and transcription mechanisms that determine pancreatic cell fate decisions toward regeneration and malignancy. In particular, we studied the function and regulation of the inflammatory transcription factor nuclear factor of activated T cells 1 (NFATC1) in pancreatic cell plasticity and tissue adaptation...
February 7, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28187629/review-of-the-genus-i-lanchnophorus-i-hemiptera-heteroptera-rhyparochromidae-with-description-of-three-new-species-and-other-nomenclatural-changes
#13
Petr Kment, Attilio Carapezza, Zdeněk Jindra, Előd Kondorosy
The generic name Lanchnophorus Reuter, 1887, deemed for a long time to be unavailable as incorrect original spelling of Lachnophorus (in fact Lachnophorus Distant, 1903 is an unjustified emendation of the former), is restored as a valid name of the genus. Lachnesthus Bergroth, 1915, syn. nov. (new name for the preoccupied Lachnophorus Distant, 1903) is considered junior synonym of Lanchnophorus. The following nomenclatural changes are proposed: Lanchnophorus flavus (Scudder, 1971) comb. nov. = Lachnesthus chinai Scudder, nomen nudum; Lanchnophorus guttulatus Reuter, 1887, comb...
January 25, 2017: Zootaxa
https://www.readbyqxmd.com/read/28181684/exercise-based-cardiac-rehabilitation-for-adults-with-atrial-fibrillation
#14
REVIEW
Signe S Risom, Ann-Dorthe Zwisler, Pernille P Johansen, Kirstine L Sibilitz, Jane Lindschou, Christian Gluud, Rod S Taylor, Jesper H Svendsen, Selina K Berg
BACKGROUND: Exercise-based cardiac rehabilitation may benefit adults with atrial fibrillation or those who had been treated for atrial fibrillation. Atrial fibrillation is caused by multiple micro re-entry circuits within the atrial tissue, which result in chaotic rapid activity in the atria. OBJECTIVES: To assess the benefits and harms of exercise-based rehabilitation programmes, alone or with another intervention, compared with no-exercise training controls in adults who currently have AF, or have been treated for AF...
February 9, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28181608/consecutive-reactions-of-small-free-tantalum-clusters-with-dioxygen-controlled-by-relaxation-dynamics
#15
J F Eckhard, D Neuwirth, C Panosetti, H Oberhofer, K Reuter, M Tschurl, U Heiz
The reaction of small cationic tantalum clusters (Tan(+), n = 4-8) with molecular oxygen is studied under multi-collision conditions in the gas phase, and the reaction kinetics are analyzed in order to elucidate underlying mechanisms. Reaction pathways as well as relevant apparent rate constants are reported. Two principal pathways in the consecutive oxidation reaction are present in this size regime: solely oxidative degradation (loss of a TaO fragment) in the beginning followed by parallel intact oxidation of certain intermediate species...
February 9, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28180931/intensive-care-medicine-in-2050-perioperative-critical-care
#16
Zsolt Molnár, Jan Benes, Daniel A Reuter
No abstract text is available yet for this article.
February 8, 2017: Intensive Care Medicine
https://www.readbyqxmd.com/read/28177964/contemporary-gleason-grading-of-prostatic-carcinoma-an-update-with-discussion-on-practical-issues-to-implement-the-2014-international-society-of-urological-pathology-isup-consensus-conference-on-gleason-grading-of-prostatic-carcinoma
#17
Jonathan I Epstein, Mahul B Amin, Victor E Reuter, Peter A Humphrey
The primary proceedings of the 2014 International Society of Urological Pathology Grading Conference were published promptly in 2015 and dealt with: (1) definition of various grading patterns of usual acinar carcinoma, (2) grading of intraductal carcinoma; and (3) support for the previously proposed new Grade Groups. The current manuscript in addition to highlighting practical issues to implement the 2014 recommendations, provides an updated perspective based on numerous studies published after the 2014 meeting...
February 7, 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28174018/evolving-plastic-responses-to-external-and-genetic-environments
#18
Max Reuter, M Florencia Camus, Mark S Hill, Filip Ruzicka, Kevin Fowler
Phenotypic plasticity can mitigate adaptive trade-offs in fluctuating environments but how plasticity arises is little known. New research documents this process in a bacterial system. We highlight remarkable parallels to the evolution of sexual dimorphism and argue that their approach can aid our understanding of adaptive conflicts between the sexes.
February 4, 2017: Trends in Genetics: TIG
https://www.readbyqxmd.com/read/28169048/creating-a-drug-law-enforcement-research-agenda
#19
Peter Reuter
Drug law enforcement (DLE) research has been poorly funded relative to drug treatment research. The literature is slight in volume and not yet very insightful. Taking the lack of funding to represent a chronic lack of public interest in the effects of DLE, the article offers a set of suggestions for how to create of a stronger DLE research community.
February 3, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28158042/high-speed-two-dimensional-synchrotron-white-beam-x-ray-radiography-of-spray-breakup-and-atomization
#20
Benjamin R Halls, Christopher D Radke, Benjamin J Reuter, Alan L Kastengren, James R Gord, Terrence R Meyer
High-speed, two-dimensional synchrotron x-ray radiography and phase-contrast imaging are demonstrated in propulsion sprays. Measurements are performed at the 7-BM beamline at the Advanced Photon Source user facility at Argonne National Laboratory using a recently developed broadband x-ray white beam. This novel enhancement allows for high speed, high fidelity x-ray imaging for the community at large. Quantitative path-integrated liquid distributions and spatio-temporal dynamics of the sprays were imaged with a LuAG:Ce scintillator optically coupled to a high-speed CMOS camera...
January 23, 2017: Optics Express
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