Devprakash Choudhary, K S Lekshmon, Charanpreet Singh, Vanji N Subramani, Yogendra Singh, Suvradeep Mitra, Aravind Sekar, Manaswinee Malik, Naveen Bhagat, S P Shiva Kumar, Sunil Taneja, Vikas Gupta, Raja Ramachandran, Sarbpreet Singh, Ritambhra Nada, Deepesh Kenwar, Ajay K Duseja, T D Yadav, Pankaj Malhotra, Ashish Sharma
Organ transplantation is the primary therapy for organ failure caused by telomere biology disorder (TBD). We describe the first documented case of simultaneous liver and kidney transplantation (SLKTx) for TBD, although the diagnosis of TBD was reached only three months following SLKTx. The patient was born prematurely, displayed growth retardation, and developed chronic kidney and liver diseases. His pre-SLKTx autoimmune, metabolic, and viral assessments were negative, and persistent pancytopenia (bone marrow cellularity 70-80%) was attributed to renal disease-associated bone marrow changes...
2024: Journal of Clinical and Experimental Hepatology