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Childhood trauma

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https://www.readbyqxmd.com/read/29775876/childhood-abuse-and-depression-in-adulthood-the-mediating-role-of-allostatic-load
#1
Sandra Scheuer, Nicole Wiggert, Tanja Maria Brückl, Yvonne Awaloff, Manfred Uhr, Susanne Lucae, Stefan Kloiber, Florian Holsboer, Marcus Ising, Frank H Wilhelm
BACKGROUND: Traumatic experiences during childhood are considered a major risk factor for depression in adulthood. Childhood trauma may induce physiological dysregulation with long-term effects of increased allostatic load until adulthood, which may lead to depression. Thus, our aim was to investigate whether allostatic load - which represents a multi-system measure of physiological dysregulation - mediates the association between childhood trauma and adult depression. METHODS: The study sample consisted of 324 depressed inpatients participating in the Munich Antidepressant Response Signature (MARS) project and 261 mentally healthy control participants...
April 22, 2018: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29775870/adverse-and-adaptive-childhood-experiences-are-associated-with-parental-reflective-functioning-in-mothers-with-substance-use-disorder
#2
Ulrika Håkansson, Reidulf Watten, Kerstin Söderström, Finn Skårderud, Merete Glenne Øie
Mothers with a substance use disorder (SUD) are at risk for maladaptive parenting practices, and have heightened likelihood of having experienced childhood adversity themselves. In addition, parental reflective functioning (PRF), a capacity underlying sensitive caregiving, is often low in mothers with SUD. This study examines the relationship between PRF and aversive (emotional, physical, sexual abuse and neglect) and adaptive (safety and competence) experiences, in different developmental phases (early childhood, latency, and adolescence) in mothers with a SUD...
May 15, 2018: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29766600/effect-of-childhood-adversities-on-alcohol-problems-is-mainly-mediated-by-depression
#3
Raimo K R Salokangas, Tiina From, Sinikka Luutonen, Henri R W Salokangas, Jarmo Hietala
BACKGROUND AND OBJECTIVES: We aimed to study how five childhood adversities and trauma (CAT) core domains: emotional abuse (EmoAb), physical abuse (PhyAb), sexual abuse (SexAb), emotional neglect (EmoNeg), physical neglect (PhyNeg), associate with alcohol problems (APs), and whether there are any gender differences in these associations. METHODS: Altogether, 690 adult participants drawn from the general population completed a mailed questionnaire, including the trauma and distress scale, as an indicator of CAT, and questions concerning sociodemographic background, depressive symptoms, and APs...
May 15, 2018: American Journal on Addictions
https://www.readbyqxmd.com/read/29764522/treatment-resistant-depression-and-peripheral-c-reactive-protein
#4
Samuel R Chamberlain, Jonathan Cavanagh, Peter de Boer, Valeria Mondelli, Declan N C Jones, Wayne C Drevets, Philip J Cowen, Neil A Harrison, Linda Pointon, Carmine M Pariante, Edward T Bullmore
BACKGROUND: C-reactive protein (CRP) is a candidate biomarker for major depressive disorder (MDD), but it is unclear how peripheral CRP levels relate to the heterogeneous clinical phenotypes of the disorder.AimTo explore CRP in MDD and its phenotypic associations. METHOD: We recruited 102 treatment-resistant patients with MDD currently experiencing depression, 48 treatment-responsive patients with MDD not currently experiencing depression, 48 patients with depression who were not receiving medication and 54 healthy volunteers...
May 16, 2018: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/29761341/the-prevalence-of-developmental-defects-of-enamel-a-prospective-cohort-study-of-adolescents-in-western-sweden-a-barn-i-tanadvarden-bita-children-in-dental-care-study
#5
B Jälevik, A Szigyarto-Matei, A Robertson
AIM: To describe the prevalence of different types of developmental defects of the enamel (DDE) in varying age-cohorts and habitations, and to analyse if early trauma to the primary teeth and early subsequent serious health problems were related to DDE in the permanent dentition. Dental fear and anxiety, and aesthetic problems as a consequence of DDE were also investigated. METHODS: DDE was registered over 5 years annually in three age cohorts (796 children). The DDE index (FDI Commision on Oral Health, Research and Epidemiology, Int Dent J 42:411-426, 1992) was used...
May 14, 2018: European Archives of Paediatric Dentistry: Official Journal of the European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/29759850/differences-in-prehospital-patient-assessments-for-pediatric-versus-adult-patients
#6
Sriram Ramgopal, Jonathan Elmer, Jeremiah Escajeda, Christian Martin-Gill
OBJECTIVE: To evaluate whether completion of vital signs assessments in pediatric transports by emergency medical services (EMS) differs by patient age. STUDY DESIGN: We reviewed records by 20 agencies in a regional EMS system in Southwestern Pennsylvania between April 1, 2013 and December 31, 2016. We abstracted demographics, vital signs (systolic blood pressure, heart rate, respiratory rate), clinical, and transport characteristics. We categorized age as neonates (≤30 days), infants (1 month to <1 year), toddler (1 to <2 years), early childhood (2 to <6 years), middle childhood (6 to <12 years), adolescent (12 to <18 years), and adult (≥18 years)...
May 11, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29755392/psychometric-properties-of-the-chinese-version-of-the-brief-borderline-symptom-list-in-undergraduate-students-and-clinical-patients
#7
Huihui Yang, Xiaoxia Lei, Mingtian Zhong, Qi Zhou, Yu Ling, Martin Jungkunz, Jinyao Yi
The brief version of the Borderline Symptom List (BSL-23) is a self-rated scale developed from the initial 95-item version of Borderline Symptom List (BSL-95). The current study aimed to evaluate the psychometric properties of the Chinese version of the BSL-23. A total of 570 undergraduate students and 323 clinical patients completed the BSL-23, the borderline subscale of the Personality Diagnostic Questionnaire (PDQ-4+), the Center for Epidemiologic Studies Depression Scale (CES-D), the Barratt Impulsiveness Scale, 11th version (BIS-11), the Childhood Trauma Questionnaire (CTQ) and the Attachment Style Questionnaire (ASQ)...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29755375/influence-of-crhr1-polymorphisms-and-childhood-abuse-on-suicide-attempts-in-affective-disorders-a-gxe-approach
#8
Birgit Ludwig, Klemens Kienesberger, Laura Carlberg, Patrick Swoboda, Alexandra Bernegger, Romina Koller, Qingzhong Wang, Michelle Inaner, Melanie Zotter, Nestor D Kapusta, Helmuth Haslacher, Martin Aigner, Siegfried Kasper, Alexandra Schosser
Background: Previous studies have shown that the hypothalamus-pituitary-adrenal-axis (HPA-axis) is closely involved in the development of affective disorders. Given that early life events are also linked to dysregulation of the same system, there might be an association between childhood adversities and suicidal behavior in affective disorders, moderated by HPA-axis genes. We aimed to investigate a potential association between childhood trauma and previous suicide attempts in affective disorder patients, moderated by variants of the corticotropin-releasing hormone receptor 1 (CRHR1) gene...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29752663/understanding-the-pathways-between-mothers-childhood-maltreatment-experiences-and-patterns-of-insecure-attachment-with-young-children-via-symptoms-of-depression
#9
Maria Khan, Kimberly Renk
Although research has suggested that mothers who experienced childhood maltreatment tend to exhibit heightened risk for attachment difficulties with their young children, less is known about the mechanisms underlying this association. Thus, this study examined mothers' symptoms of depression as a mediator in the relationship between mothers' childhood maltreatment experiences and patterns of insecure (i.e., anxious, avoidant, and disorganized) mother-young child attachment. Mothers (N = 146) with children aged 1½-to 5-years provided ratings of their childhood maltreatment experiences, attachment with their young children, and symptoms of depression...
May 11, 2018: Child Psychiatry and Human Development
https://www.readbyqxmd.com/read/29748862/association-of-dna-methylation-in-bdnf-with-escitalopram-treatment-response-in-depressed-chinese-han-patients
#10
Peipei Wang, Cuizhen Zhang, Qinyu Lv, Chenxi Bao, Hong Sun, Guo Ma, Yiru Fang, Zhenghui Yi, Weimin Cai
PURPOSE: The neurotrophin brain-derived neurotrophic factor (BDNF) has been found to be associated with both the pathophysiology of depression and antidepressants response. Gene expression differences were partly mediated by SNP, which might be identified as a predictor of antidepressant response. In the present study, we attempt to identify whether DNA methylation, another factor known to affect gene transcription, might also predict antidepressant response. METHODS: A total of 85 depressed Chinese Han patients were followed-up 8 weeks after initiating escitalopram treatment...
May 10, 2018: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29745293/mothers-insightfulness-regarding-their-children-s-inner-world-associations-with-mothers-history-of-sexual-abuse-and-lack-of-resolution-of-the-trauma
#11
Nina Koren-Karie, Rachel Getzler-Yosef
The study examined the insightfulness of mothers who experienced Childhood Sexual Abuse (CSA). Based on attachment theory, we hypothesized that mothers who experienced CSA will be less insightful than those who did not experience CSA, and that state of mind with no marked signs of lack of resolution of the trauma can buffer against its negative effects. The insightfulness of 30 mothers who experienced CSA and 30 demographically matched mothers but with no CSA was assessed using the Insightfulness Assessment...
May 10, 2018: Attachment & Human Development
https://www.readbyqxmd.com/read/29743139/the-relationship-between-the-level-of-exposure-to-stress-factors-and-cannabis-in-recent-onset-psychosis
#12
Sara Arranz, Nuria Monferrer, M Jose Algora, Angel Cabezas, Montse Sole, E Vilella, J Labad, Vanessa Sanchez-Gistau
BACKGROUND: There is a lack of studies investigating the dose-response effect of childhood trauma, recent events and cannabis use on recent psychosis. This study aims to determine the relationship between the level of exposure to stress factors and cannabis use with psychosis and to determine the combination effect among these factors in predicting a psychotic disorder. METHODS: 146 recent onset psychotic (ROP) patients and 61 healthy controls were included. Childhood trauma was evaluated using the childhood trauma questionnaire (CTQ) and recent events using the Holmes-Rahe social readjustment scale...
May 6, 2018: Schizophrenia Research
https://www.readbyqxmd.com/read/29741208/induction-of-labour-for-improving-birth-outcomes-for-women-at-or-beyond-term
#13
REVIEW
Philippa Middleton, Emily Shepherd, Caroline A Crowther
BACKGROUND: Beyond term, the risks of stillbirth or neonatal death increase. It is unclear whether a policy of labour induction can reduce these risks. This Cochrane review is an update of a review that was originally published in 2006 and subsequently updated in 2012 OBJECTIVES: To assess the effects of a policy of labour induction at or beyond term compared with a policy of awaiting spontaneous labour or until an indication for birth induction of labour is identified) on pregnancy outcomes for infant and mother...
May 9, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29739182/combining-extracorporeal-membrane-oxygenation-and-in-line-hemofiltration-for-acute-hyperkalemic-cardiac-arrest-in-a-patient-with-duchenne-muscular-dystrophy-following-orthopedic-surgery
#14
Sang Hun Kim, Ji Ho Song, Ki Tae Jung
Duchenne muscular dystrophy (DMD) is the most common childhood muscular dystrophy that anesthesiologists can encounter in the operation room, and patients with DMD are susceptible to complications such as rhabdomyolysis, hyperkalemic cardiac arrest, and hyperthermia during the perioperative period. Acute onset of hyperkalemic cardiac arrest is a crisis because of the difficulty in achieving satisfactory resuscitation owing to the sustained hyperkalemia accompanied by rhabdomyolysis. We here report a case of a 13-year-old boy who had multiple leg fractures and other trauma after a car accident and who had suffered from acute hyperkalemic cardiac arrest...
May 9, 2018: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/29739129/evaluation-of-relationship-between-obsessive-compulsive-disorder-and-dissociative-experiences
#15
Mustafa Tatlı, Ozlem Cetinkaya, Fulya Maner
Objective: The aim of the study is to evaluate the relationship between obsessive-compulsive disorder (OCD) symptoms and dissociative experiences and the effect of childhood traumatic experiences on this relationship in OCD patients. Methods: Fifty consecutive OCD patients and 50 healthy controls are enrolled for this study. Sociodemographic and Clinical Data Form, Dissociative Experiences Scale (DES), Padua Inventory (PI) and Childhood Trauma Questionnaire (CTQ) are applied to participants...
May 31, 2018: Clinical Psychopharmacology and Neuroscience: the Official Scientific Journal of the Korean College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29738944/sex-differences-in-traumatic-events-and-psychiatric-morbidity-associated-to-probable-posttraumatic-stress-disorder-among-latino-prisoners
#16
Coralee Pérez-Pedrogo, Alfonso Martínez-Taboas, Rafael A González, José N Caraballo, Carmen E Albizu-García
Latinos comprised 17.1% of the U.S. population and 33.1% of US prisoners, yet they are underrepresented in the psychopathology literature. Despite higher rates of trauma among incarcerated individuals than in the general population, most of the previous research in this area focused primarily on women samples, and very few studies examined sex differences in PTSD and traumatic experiences. In addition, there is a need for research assessing traumatic experiences and probable PTSD in men and women Latino inmates to inform culturally competent care and sex sensitive care for this vulnerable and underserved population...
April 14, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29734218/depressive-symptoms-and-problematic-alcohol-and-other-substance-use-in-1-476-gay-bisexual-and-other-men-who-have-sex-with-men-at-three-research-sites-in-kenya
#17
Christine Korhonen, Makobu Kimani, Elizabeth Wahome, Fredrick Otieno, Duncan Okall, Robert C Bailey, Gary W Harper, Robert R Lorway, Monika Doshi, John Mathenge, Joshua Kimani, Eduard J Sanders, Susan M Graham
OBJECTIVE: Information on mental health and substance use challenges among gay, bisexual, and other men who have sex with men (GBMSM) is needed to focus resources on these issues and optimize services for HIV prevention and care. We determined factors associated with depressive symptoms and problematic alcohol and other substance use among GBMSM in Kenya. METHODS: Self-identified GBMSM in three HIV research studies in Kenya provided information on depressive symptoms (PHQ-9), alcohol use (AUDIT), and other substance use (DAST-6)...
May 3, 2018: AIDS
https://www.readbyqxmd.com/read/29729685/common-genetic-contributions-to-high-risk-trauma-exposure-and-self-injurious-thoughts-and-behaviors
#18
Leah S Richmond-Rakerd, Timothy J Trull, Ian R Gizer, Kristin McLaughlin, Emily M Scheiderer, Elliot C Nelson, Arpana Agrawal, Michael T Lynskey, Pamela A F Madden, Andrew C Heath, Dixie J Statham, Nicholas G Martin
BACKGROUND: Prior research has documented shared heritable contributions to non-suicidal self-injury (NSSI) and suicidal ideation (SI) as well as NSSI and suicide attempt (SA). In addition, trauma exposure has been implicated in risk for NSSI and suicide. Genetically informative studies are needed to determine common sources of liability to all three self-injurious thoughts and behaviors, and to clarify the nature of their associations with traumatic experiences. METHODS: Multivariate biometric modeling was conducted using data from 9526 twins [59% female, mean age = 31...
May 6, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29725700/profiles-of-childhood-trauma-and-psychopathology-us-national-epidemiologic-survey
#19
Emma Curran, Gary Adamson, Michael Rosato, Paul De Cock, Gerard Leavey
PURPOSE: Childhood trauma may increase vulnerability to numerous specific psychiatric disorders, or a generalised liability to experience dimensions of internalising or externalising psychopathology. We use a nationally representative sample (N = 34,653) to examine the long-term consequences of childhood trauma and their combined effect as predictors of subsequent psychopathology. METHODS: Data from the US National Epidemiologic Survey on Alcohol and Related Conditions were used...
May 3, 2018: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/29724430/acr-appropriateness-criteria-%C3%A2-hematuria-child
#20
Jonathan R Dillman, Cynthia K Rigsby, Ramesh S Iyer, Adina L Alazraki, Sudha A Anupindi, Brandon P Brown, Sherwin S Chan, Scott R Dorfman, Richard A Falcone, Matthew D Garber, Jie C Nguyen, Craig A Peters, Nabile M Safdar, Andrew T Trout, Boaz K Karmazyn
Hematuria is the presence of red blood cells in the urine, either visible to the eye (macroscopic hematuria) or as viewed under the microscope (microscopic hematuria). The clinical evaluation of children and adolescents with any form of hematuria begins with a meticulous history and thorough evaluation of the urine. The need for imaging evaluation depends on the clinical scenario in which hematuria presents, including the suspected etiology. Ultrasound and CT are the most common imaging methods used to assess hematuria in children, although other imaging modalities may be appropriate in certain instances...
May 2018: Journal of the American College of Radiology: JACR
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