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https://www.readbyqxmd.com/read/30222063/proliferative-typhlocolitis-with-multinucleated-giant-cells-a-nonspecific-enteropathy-in-immunodeficient-sentinel-mice
#1
Kerriann M Casey, Amanda L Johnson, Melea N Hunrath, Jenelle K Fraser, Nicole C McCowan, Katherine Wasson, Rosalinda A Doty, Stephen M Griffey, Denise M Imai
Beginning in 2015, athymic nude sentinel mice from conventional, medium-, and high-security facilities presented to the Comparative Pathology Laboratory (CPL) with weight loss, diarrhea, and/or rectal prolapse. Regardless of whether clinical signs were present or absent, the gross observation of ceco-colonic thickening corresponded histologically to pleocellular typhlocolitis with mucosal hyperplasia and lamina proprial multinucleated cells. A subset of affected sentinels exhibited granulomatous serositis and hepatosplenic necrosis with multinucleated cells...
September 16, 2018: Veterinary Pathology
https://www.readbyqxmd.com/read/30221633/comparative-analysis-of-laparoscopic-sleeve-gastrectomy-and-roux-en-y-gastric-bypass-procedures-for-the-treatment-of-morbid-obesity
#2
Riza Gurhan Isil, Mehmet Mihmanli, Pinar Yazici, Canan Tulay Isil, Uygar Demir, Cemal Kaya, Ozgur Bostanci
BACKGROUND: Roux-en-Y gastric bypass (RYGB) has been considered as the most efficient method in bariatric surgery. Indeed, Laparoscopic Sleeve Gastrectomy (LSG) which is easier to do, has been increasingly used in the recent years. The aim of the present study was to compare short-and mid-term outcomes of RYGB and LSG. METHODS: Medical records of 62 patients who underwent either RYGB (GroupR) or LSG (GroupL) in our General Surgery Department between 2010 and 2013 were retrospectively reviewed...
July 31, 2018: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/30220074/obesity-and-sexual-functioning
#3
REVIEW
David B Sarwer, Alexis J Hanson, Jessica Voeller, Kristine Steffen
PURPOSE OF THE REVIEW: Sexual functioning is an important, yet often overlooked, aspect of quality of life for many individuals with obesity. RECENT FINDINGS: With the growing recognition of obesity as a significant, international public health issue, a developing body of research has investigated the relationship between obesity and sexual functioning. Several studies have found that obesity is associated with impairments in sexual functioning. The mechanisms of this relationship, whether physiological, psychosocial, or a combination of the two, are yet to be fully elucidated...
September 15, 2018: Current Obesity Reports
https://www.readbyqxmd.com/read/30219783/unusual-presentation-of-pancreatitis-with-extrapancreatic-manifestations
#4
Tony Fordham, Helen Marie Sims, Terence Farrant
Pancreatitis, panniculitis and polyarthritis syndrome (PPP syndrome) is a rare and complex manifestation of pancreatitis that is currently reported in few cases. We present this case regarding a 77-year-old man who presented unusually with a 6-week history of bilateral lesions on his lower limbs. During this time, he experienced increasing fatigue, joint pain, and reported fevers and significant weight loss. An incidental serum amylase was found to be significantly elevated and remained elevated throughout his 2-month hospital stay...
September 15, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/30219686/weight-loss-and-metabolic-improvements-in-obese-patients-undergoing-gastric-banding-and-gastric-banded-plication-a-comparison
#5
Weu Wang, Cathy S J Fann, Shwu-Huey Yang, Hsin-Hung Chen, Chih-Yen Chen
OBJECTIVES: Obesity is a pandemic health problem. Bariatric surgery is the only efficient method for long-term effective weight loss in subjects with severe obesity. Laparoscopic adjustable gastric banding (LAGB) has been widely applied for weight loss. However, a novel technique called laparoscopic adjustable gastric banded plication (LAGBP) has been proposed as an alternative to LAGB. Surgeons generally consider LAGBP to have a relative advantage on weight loss than that derived from LAGB...
June 18, 2018: Nutrition
https://www.readbyqxmd.com/read/30219433/spirulina-platensis-effectively-ameliorates-anthropometric-measurements-and-obesity-related-metabolic-disorders-in-obese-or-overweight-healthy-individuals-a-randomized-controlled-trial
#6
Reyhaneh Yousefi, Azadeh Mottaghi, Atoosa Saidpour
AIMS: Novel alternative treatments such as food supplements may be an effective approach to weight management. The aim of the present study was to investigate the possible effects of Spirulina Platensis (SP) on anthropometric measures, appetite and metabolic parameters in obese or overweight individuals. MATERIAL AND METHODS: A total of fifty-two obese and overweight subjects (25 kg/m2  ≤ body mass index (BMI) <40 kg/m2 ) were randomly selected to be allocated to SP (4 × 500 mg daily tablets along with restricted calorie diet (RCD)) or placebo (placebo tablets along with RCD) for 12 weeks of intervention...
October 2018: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/30219318/comparison-of-early-and-recent-influenza-a-h1n1-pdm09-isolates-harboring-or-not-the-h275y-neuraminidase-mutation-in-vitro-and-in-animal-models
#7
Yacine Abed, Véronique Tu, Julie Carbonneau, Liva Checkmahomed, Marie-Christine Venable, Clément Fage, Marie-Ève-Hamelin, Simon F Dufresne, Gary Kobinger, Guy Boivin
After 6 years of circulation in humans, a novel antigenic variant of influenza A(H1N1)pdm09 (i.e., A/Michigan/45/2015) emerged in 2015-16 and has predominated thereafter worldwide. Herein, we compared in vitro and in vivo properties of 2016 wild-type (WT) A/Michigan/45/15-like isolate and its H275Y neuraminidase (NA) variant to the original A/California/07/09-like counterparts. The H275Y mutation induced comparable levels of resistance to oseltamivir and peramivir without altering zanamivir susceptibility in both 2009 and 2016 isolates...
September 13, 2018: Antiviral Research
https://www.readbyqxmd.com/read/30219155/modifiable-predictors-of-in-hospital-mortality-in-patients-undergoing-transcatheter-aortic-valve-replacement
#8
Oluwaseun A Akinseye, Muhammad Shahreyar, Chioma C Nwagbara, Mannu Nayyar, Salem A Salem, Mohamed Morsy, Rami N Khouzam, Uzoma N Ibebuogu
BACKGROUND: Transcatheter aortic valve replacement (TAVR) has become an acceptable therapy for patients with severe aortic valve stenosis at high or prohibitive surgical risk. Attempts are ongoing to validate risk prediction models for in-hospital mortality after TAVR. Our aim was to define modifiable risk factors predictive of in-hospital mortality after TAVR. METHODS: We identified patients who underwent TAVR from the 2012 database of the National Inpatient Sample...
August 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/30219081/change-in-health-and-social-factors-in-mid-adulthood-and-corresponding-changes-in-leisure-time-physical-inactivity-in-a-prospective-cohort
#9
Snehal M Pinto Pereira, Chris Power
BACKGROUND: To identify whether changes in adult health and social factors are associated with simultaneous changes in inactivity. METHODS: Health, social factors and leisure-time inactivity (activity frequency < 1/week) were self-reported at 33y and 50y in the 1958 British birth cohort (N = 12,271). Baseline (33y) health and social factors and also patterns of change in factors 33y-to-50y were related to inactivity 33y-to-50y (never inactive, persistently inactive, deteriorating to inactivity, or improving from inactivity) using multinomial logistic regression...
September 15, 2018: International Journal of Behavioral Nutrition and Physical Activity
https://www.readbyqxmd.com/read/30219028/vedolizumab-use-after-failure-of-tnf-%C3%AE-antagonists-in-children-and-adolescents-with-inflammatory-bowel-disease
#10
Anna-Maria Schneider, Daniel Weghuber, Benjamin Hetzer, Andreas Entenmann, Thomas Müller, Georg Zimmermann, Sebastian Schütz, Wolf-Dietrich Huber, Judith Pichler
BACKGROUND: Vedolizumab is safe and effective in adult patients with Crohn's disease (CD) and ulcerative colitis (UC); however, data in children with inflammatory bowel disease (IBD) are scarce. Therefore, we evaluated vedolizumab use in a cohort of Austrian paediatric patients with IBD. METHODS: Twelve patients (7 female; 7 CD; 5 UC), aged 8-17 years (median, 15 years), with severe IBD who received vedolizumab after tumour necrosis factor α antagonist treatment were retrospectively analysed...
September 15, 2018: BMC Gastroenterology
https://www.readbyqxmd.com/read/30218929/quantifying-n-loss-by-root-abscission-consequences-for-wheat-n-budgets-and-%C3%AE-15-n-values
#11
Kirsten F Packer, Michael D Cramer
Lower plant δ15 N values relative to source δ15 N are commonly attributed to 15 N efflux. We determined the extent to which root abscission contributes to plant N-loss and consequences for plant δ15 N. Wheat (Triticum aestivum L. cv. SST015) was grown in hydroponics with direct aeration, aeration constrained within a pipe and circulation of nutrient solution through sand, representing three levels of stability for root growth. The δ15 N of nutrient solutions and root fragments were periodically determined, as well as root and shoot δ15 N...
September 1, 2018: Journal of Plant Physiology
https://www.readbyqxmd.com/read/30218433/diabetes-and-diet-a-patient-and-dietitian-s-perspective
#12
Carole Sergeant, Pamela A Dyson
This article has been co-authored by a patient with type 2 diabetes and a specialist dietitian. Here they discuss the patient's experience and difficulties with controlling weight and strategies that can help a patient in this situation. The patient discusses how stress and her corresponding comfort eating dampened weight loss progress, and how adopting a lifestyle change aided through group support helped to deal with this. The physician discusses the importance of recognizing the mental and physical challenges faced by patients in this situation...
September 14, 2018: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/30218406/prevalence-of-sarcopenia-and-9-year-mortality-in-nursing-home-residents
#13
Stany Perkisas, Anne-Marie De Cock, Maurits Vandewoude, Veronique Verhoeven
BACKGROUND: Sarcopenia is a progressive loss of muscle mass, strength, and function. It is linked to functional decline, and secondary to this, to nursing home admission. AIMS: To look into the prevalence of sarcopenia in a nursing home population and to gain insight into the relation of sarcopenia with mortality in this cohort. METHODS: A longitudinal cohort follow-up started in October 2007 in 52 nursing homes in Belgium. Following data were procured: anthropometrics (weight/length), body composition (muscle mass through bio-impedance absorptiometry, BIA), functional status (Katz), nutritional status (mini-nutritional assessment-short form, MNA), and a number of laboratory parameters...
September 14, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/30218196/supplementation-adherence-and-outcomes-among-pregnant-women-after-bariatric-surgery
#14
Silvia Leite Faria, Orlando Pereira Faria, Heloisa Rodrigues de Gouvêa, Angelica Amorim Amato
PURPOSE: Most patients undergoing bariatric surgery (BS) are fertile women whose postoperative (post-op) hormonal balance and weight loss increases fertility, frequently leading to pregnancy. This study aims to analyze supplementation adherence of pregnant women after BS and perinatal outcomes. MATERIALS AND METHODS: This retrospective study analyzed records from women after BS who consulted nutritionists at least twice during pregnancy. Each patient received nutritional guidance about vitamin and mineral supplementation and protein intake...
September 15, 2018: Obesity Surgery
https://www.readbyqxmd.com/read/30218019/nicotine-and-sleep-deprivation-impact-on-pain-sensitivity-and-immune-modulation-in-rats
#15
Camila Hirotsu, Matheus Negrao Pedroni, Laís Fernanda Berro, Sergio Tufik, Monica Levy Andersen
Repeated nicotine administration has been associated with increased paradoxical sleep in rats and antinociceptive properties, whereas paradoxical sleep deprivation (PSD) elicits pronociceptive and inflammatory responses. Thus, we aimed to evaluate the effect of repeated nicotine administration and its withdrawal combined with PSD on pain sensitivity and inflammatory markers. Sixty adult male Wistar rats were subjected to repeated injections of saline (SAL) or nicotine (NIC) for 12 days or 7 days of nicotine followed by acute mecamylamine administration on day 8 to precipitate nicotine abstinence (ABST)...
September 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/30217029/the-beneficial-effect-of-proanthocyanidins-and-icariin-on-biochemical-markers-of-bone-turnover-in-rats
#16
Nada Oršolić, Johann Nemrava, Željko Jeleč, Marina Kukolj, Dyana Odeh, Svjetlana Terzić, Rajko Fureš, Tomica Bagatin, Dinko Bagatin
Nutrition is an important factor that influences bone metabolism, the endocrine and/or paracrine system, and bone-active mineral elements homeostasis. We studied antiosteoporotic effects of grape seed proanthocyanidins extract, icariin or alendronate (ALN) in retinoic acid-induced (13cRA) bone loss in rats. Proanthocyanidins and icariin have beneficial effects on bone health; they have improved the bone weight reduction, the length and the diameter of the bone, calcium, and phosphorus content in bone ash, bone mineral density (BMD), the biochemical markers of bone turnover and uterus atrophy induced by 13cRA...
September 13, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/30217013/the-degradation-properties-of-mgo-whiskers-plla-composite-in-vitro
#17
Yun Zhao, Bei Liu, Hongwei Bi, Jinjun Yang, Wei Li, Hui Liang, Yue Liang, Zhibin Jia, Shuxin Shi, Minfang Chen
In this study, composite films of stearic acid⁻modified magnesium oxide whiskers (Sa⁻w-MgO)/poly-l-lactic acid (PLLA) were prepared through solution casting, and the in vitro degradation properties and cytocompatibility of the composites with different whisker contents were investigated. The results showed that the degradation behavior of the composite samples depended significantly on the whisker content, and the degradation rate increased with the addition of MgO content. Furthermore, the degradation of the composites with higher contents of whiskers was influenced more severely by the hydrophilicity and pH value, leading to more final weight loss, but the decomposition rate decreased gradually...
September 13, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/30216730/safety-of-8-h-time-restricted-feeding-in-adults-with-obesity
#18
Kelsey Gabel, Kristin K Hoddy, Krista A Varady
This study examines the safety of time restricted feeding (TRF; 8-h feeding window/16-h fasting window daily) in obese adults. Twenty-three subjects participated in an 8-h TRF intervention for 12 weeks. Self-reported adverse events, body image perception, complete blood count and disordered eating patterns did not change from baseline to week 12. These findings suggest that consuming food within an 8-h window can safely facilitate weight loss in subjects with obesity.
September 14, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/30216556/autopsy-case-of-v180i-genetic-creutzfeldt-jakob-disease-presenting-with-early-disease-pathology
#19
Yasushi Iwasaki, Hiroko Kato, Tetsuo Ando, Akio Akagi, Maya Mimuro, Hiroaki Miyahara, Tetsuyuki Kitamoto, Mari Yoshida
The patient was a Japanese woman who experienced a decrease in activity and gait disturbance as the initial symptoms at the age of 86, followed by disorientation and memory dysfunction. Magnetic resonance imaging showed extensive cortical regions with hyperintensity in diffusion-weighted images, and these regions showed swelling in T2-weighted and fluid-attenuated inversion recovery (FLAIR) images. The medial occipital cortex and striatum showed no apparent hyperintensity on diffusion-weighted imaging (DWI)...
September 14, 2018: Neuropathology: Official Journal of the Japanese Society of Neuropathology
https://www.readbyqxmd.com/read/30216555/minimally-invasive-robot-assisted-procedure-for-kidney-transplantation-among-morbidly-obese-positive-outcomes-at-five-years-post-transplant
#20
Mario Spaggiari, Frances Rose Lendacki, Caterina Di Bella, Pier Cristoforo Giulianotti, Enrico Benedetti, Jose Oberholzer, Ivo Tzvetanov
The pre-transplant weight loss required of end-stage renal disease patients is often unachievable. Though robot-assisted procedures among extremely obese have shown minimal complication, long-term outcomes are understudied. Previously, we reported no difference in 6-month patient and graft survival among 28 robot-assisted transplant cases (2009-2013), and 28 open controls (2004-2010). Groups were frequency-matched on age, sex, race, donor compatibility, disease and dialysis history. Cases had greater median pre-transplant BMI (42...
September 14, 2018: Clinical Transplantation
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