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https://www.readbyqxmd.com/read/28438010/study-on-crystallographic-orientation-effect-on-surface-generation-of-aluminum-in-nano-cutting
#1
Feifei Xu, Fengzhou Fang, Yuanqing Zhu, Xiaodong Zhang
The material characteristics such as size effect are one of the most important factors that could not be neglected in cutting the material at nanoscale. The effects of anisotropic nature of single crystal materials in nano-cutting are investigated employing the molecular dynamics simulation. Results show that the size effect of the plastic deformation is based on different plastic carriers, such as the twin, stacking faults, and dislocations. The minimum uncut chip thickness is dependent on cutting direction, where even a negative value is obtained when the cutting direction is {110}<001>...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28438006/measurements-and-modeling-of-multipath-interference-at-wavelengths-below-cable-cut-off-in-a-g-654-optical-fiber-span
#2
John D Downie, Jason Hurley, Hector DePedro, Steven Garner, Jeremy Blaker, Aramais Zakharian, Sergey Ten, Greg Mills
Transmission below the cable cut-off wavelength may be a concern in some systems, especially for an optical supervisory channel (OSC) operating below the signal transmission band in systems built with G.654 fiber. In this work, we constructed a cabled span of G.654-compliant fiber and measured the multipath interference (MPI) generated during propagation through the span at a range of wavelengths below the cable cut-offs of the constituent fibers. Measurements were made under a range of conditions including different splice losses and the presence or absence of higher order mode filters placed around the splices...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437999/novel-programmable-microwave-photonic-filter-with-arbitrary-filtering-shape-and-linear-phase
#3
Xiaoqi Zhu, Feiya Chen, Huanfa Peng, Zhangyuan Chen
We propose and demonstrate a novel optical frequency comb (OFC) based microwave photonic filter which is able to realize arbitrary filtering shape with linear phase response. The shape of filter response is software programmable using finite impulse response (FIR) filter design method. By shaping the OFC spectrum using a programmable waveshaper, we can realize designed amplitude of FIR taps. Positive and negative sign of FIR taps are achieved by balanced photo-detection. The double sideband (DSB) modulation and symmetric distribution of filter taps are used to maintain the linear phase condition...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437942/optical-damage-resistant-ti-diffused-zr-er-codoped-lithium-niobate-strip-waveguide-for-high-power-980-nm-pumping
#4
Wen-Bao Sun, Xiao-Fei Yang, Zi-Bo Zhang, Wing-Han Wong, Dao-Yin Yu, Edwin Yue-Bun Pun, De-Long Zhang
Ti<sup>4+</sup>-diffused Zr<sup>4+</sup>/Er<sup>3+</sup>-codoped LiNbO<sub>3</sub> strip waveguide was fabricated on an X-cut LiNbO<sub>3</sub> substrate by thermal diffusion in sequence of Er<sup>3+</sup>, Zr<sup>4+</sup> and Ti<sup>4+</sup>. Secondary ion mass spectrometry study shows that the Ti<sup>4+</sup> ions follow a sum of two error functions in the width direction and a Gauss function in the depth direction of the waveguide...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437713/reference-intervals-for-serum-24-25-dihydroxyvitamin-d-and-the-ratio-with-25-hydroxyvitamin-d-established-using-a-newly-developed-lc-ms-ms-method
#5
Jonathan C Y Tang, Holly Nicholls, Isabelle Piec, Christopher J Washbourne, John J Dutton, Sarah Jackson, Julie Greeves, William D Fraser
24,25(OH)2D is the product of 25(OH)D catabolism by CYP24A1. The measurement of serum 24,25(OH)2D concentration may serve as an indicator of vitamin D catabolic status and the relative ratio with 25(OH)D can be used to identify patients with inactivating mutations in CYP24A1. We describe a LC-MS/MS method to determine: (1) the relationships between serum 24,25(OH)2D and 25(OH)D; (2) serum reference intervals in healthy individuals; (3) the diagnostic accuracy of 24,25(OH)2D measurement as an indicator for vitamin D status; 4) 24,25(OH)2D cut-off value for clinically significant change between inadequate and sufficient 25(OH)D status...
April 12, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/28437631/age-independent-anti-m%C3%A3-llerian-hormone-amh-standard-deviation-scores-to-estimate-ovarian-function
#6
Josef van Helden, Ralf Weiskirchen
OBJECTIVIES: To determine single year age-specific anti-Müllerian hormone (AMH) standard deviation scores (SDS) for women associated to normal ovarian function and different ovarian disorders resulting in sub- or infertility. DESIGN AND METHODS: Determination of particular year median and mean AMH values with standard deviations (SD), calculation of age-independent cut off SDS for the discrimination between normal ovarian function and ovarian disorders. RESULTS: Single-year-specific median, mean, and SD values have been evaluated for the Beckman Access AMH immunoassay...
April 18, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28437625/imaging-guided-synergetic-therapy-of-orthotopic-transplantation-tumor-by-superselectively-arterial-administration-of-microwave-induced-microcapsules
#7
Shunsong Tang, Changhui Fu, Longfei Tan, Tianlong Liu, Jingsong Mao, Xiangling Ren, Hongying Su, Dan Long, Qianqian Chai, Zhongbing Huang, Xudong Chen, Jingzhuo Wang, Jun Ren, Xianwei Meng
It is an ambitious target to improve overall Hepatocellular Carcinoma therapeutic effects. Recently, MW ablation has emerged as a powerful thermal ablation technique, affording favorable survival with excellent local tumor control. To achieve better therapeutic effects of MW ablation, MW sensitizers are prepared for enhanced MW ablation to preferentially heat tumor territory. However, it is still not practicable for treatment of the orthotopic transplantation tumor. Herein, biocompatible and degradable methoxy poly(ethylene glycol)-poly(lactic-co-glycolic acid) (mPEG-PLGA) microcapsules with hierarchical structure have been designed for microwave-induced tumor therapy...
April 14, 2017: Biomaterials
https://www.readbyqxmd.com/read/28437613/evaluating-the-role-of-multidrug-resistance-protein-3-mdr3-inhibition-in-predicting-drug-induced-liver-injury-using-125-pharmaceuticals
#8
Michael D Aleo, Falgun Shah, Kan He, Paul D Bonin, A David Rodrigues
The role of bile salt export protein (BSEP) inhibition in drug-induced liver injury (DILI) has been investigated widely, while inhibition of the canalicular multidrug resistant protein 3 (MDR3) has received less attention. This transporter plays a pivotal role in secretion of phospholipids into bile and functions coordinately with BSEP to mediate the formation of bile acid-containing biliary micelles. Therefore, inhibition of MDR3 in human hepatocytes was examined across 125 drugs (70 of Most- and 55 of No-DILI-concern)...
April 24, 2017: Chemical Research in Toxicology
https://www.readbyqxmd.com/read/28437442/relationship-between-early-onset-severe-intrahepatic-cholestasis-of-pregnancy-and-higher-risk-of-meconium-stained-fluid
#9
Maria C Estiú, Maria A Frailuna, Carla Otero, Marcela Dericco, Catherine Williamson, Jose J G Marin, Rocio I R Macias
BACKGROUND: Intrahepatic cholestasis of pregnancy (ICP) is the commonest gestational liver disease. The risk of adverse fetal outcome has been associated with the severity of maternal hypercholanemia after diagnosis. OBJECTIVE: To investigate whether there is a relationship between the severity and timing of onset of hypercholanemia and the risk of meconium-stained amniotic fluid (MSAF) and adverse neonatal events. STUDY DESIGN: The study included 382 pregnancies complicated by ICP managed at a referral hospital in Buenos Aires (Argentina) between June 2009 and December 2013...
2017: PloS One
https://www.readbyqxmd.com/read/28437355/initial-correction-rate-can-be-predictive-of-the-outcome-of-brace-treatment-in-patients-with-adolescent-idiopathic-scoliosis
#10
Leilei Xu, Xiaodong Qin, Yong Qiu, Zezhang Zhu
STUDY DESIGN: A retrospective study. OBJECTIVE: To determine the definite cut-off value of initial correction rate (ICR) that could be predictive of bracing outcome in patients with adolescent idiopathic scoliosis. SUMMARY OF BACKGROUND DATA: Earlier studies showed that braced patients with a better ICR could finally have a higher probability of successful outcome. However, it remains controversial what definitive cut-off value of ICR is required to accurately predict the outcome...
May 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28437286/cut-the-gordian-knot
#11
Guenter Kirste
No abstract text is available yet for this article.
April 22, 2017: Transplantation
https://www.readbyqxmd.com/read/28437188/further-characterization-of-the-mitigation-of-radiation-lethality-by-protective-wounding
#12
Joseph R Dynlacht, Joy Garrett, Rebecca Joel, Katharina Lane, Marc S Mendonca, Christie M Orschell
There continues to be a major effort in the United States to develop mitigators for the treatment of mass casualties that received high-intensity acute ionizing radiation exposures from the detonation of an improvised nuclear device during a radiological terrorist attack. The ideal countermeasure should be effective when administered after exposure, and over a wide range of absorbed doses. We have previously shown that the administration of a subcutaneous incision of a defined length, if administered within minutes after irradiation, protected young adult female C57BL/6 mice against radiation-induced lethality, and increased survival after total-body exposure to an LD50/30 X-ray dose from 50% to over 90%...
April 24, 2017: Radiation Research
https://www.readbyqxmd.com/read/28437165/survey-for-listeria-monocytogenes-in-and-on-ready-to-eat-foods-from-retail-establishments-in-the-united-states-2010-through-2013-assessing-potential-changes-of-pathogen-prevalence-and-levels-in-a-decade
#13
John B Luchansky, Yuhuan Chen, Anna C S Porto-Fett, Régis Pouillot, Bradley A Shoyer, Rachel Johnson-DeRycke, Denise R Eblen, Karin Hoelzer, William K Shaw, Jane M van Doren, Michelle Catlin, Jeehyun Lee, Rohan Tikekar, Daniel Gallagher, James A Lindsay, Sherri Dennis
A multiyear interagency Listeria monocytogenes Market Basket Survey was undertaken for selected refrigerated ready-to-eat foods purchased at retail in four FoodNet sites in the United States. Food samples from 16 food categories in six broad groups (seafood, produce, dairy, meat, eggs, and combination foods) were collected weekly at large national chain supermarkets and independent grocery stores in California, Maryland, Connecticut, and Georgia for 100 weeks between December 2010 and March 2013. Of the 27,389 total samples, 116 samples tested positive by the BAX PCR system for L...
April 24, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28437089/%C3%AF-n-c-bond-difunctionalization-in-bridged-twisted-amides-sew-and-cut-activation-approach-to-functionalized-isoquinolines
#14
Feng Hu, Pradeep Nareddy, Roger Lalancette, Frank Jordan, Michal Szostak
A rare example of highly selective σ N-C bond difunctionalization in bridged twisted lactams through N-C cleavage has been achieved. In combination with the intramolecular Heck cyclization, this method affords a two-step bond reorganization event ("sew-and-cut") to access functionalized isoquinoline ring systems directly with high atom economy. C-H bond functionalizations directed by a weakly coordinating bridged amide bond increase scaffold diversity. Preliminary mechanistic studies on the effect of amide distortion and the role of electrophile in this unusual σ N-C amide difunctionalization are described...
April 24, 2017: Organic Letters
https://www.readbyqxmd.com/read/28436744/cognitive-screening-in-substance-users-diagnostic-accuracies-of-the-mini-mental-state-examination-addenbrooke-s-cognitive-examination-revised-and-montreal-cognitive-assessment
#15
Nicole Ridley, Jennifer Batchelor, Brian Draper, Apo Demirkol, Nicholas Lintzeris, Adrienne Withall
INTRODUCTION: Despite the considerable prevalence of cognitive impairment in substance-using populations, there has been little investigation of the utility of cognitive screening measures within this context. In the present study the accuracy of three cognitive screening measures in this population was examined-the Mini-Mental State Examination (MMSE), the Addenbrooke's Cognitive Examination-Revised (ACE-R), and the Montreal Cognitive Assessment (MoCA). METHOD: A sample of 30 treatment-seeking substance users and 20 healthy individuals living in the community were administered the screening measures and a neuropsychological battery (NPB)...
April 24, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/28436723/asymptomatic-peripheral-artery-disease-can-limit-maximal-exercise-capacity-in-chronic-obstructive-pulmonary-disease-patients-regardless-of-airflow-obstruction-and-lung-hyperinflation
#16
Ernesto Crisafulli, Chiara Scelfo, Panagiota Tzani, Marina Aiello, Giuseppina Bertorelli, Alfredo Chetta
Background Silent/asymptomatic peripheral artery disease may occur in patients with chronic obstructive pulmonary disease, but it is poorly investigated. The primary aim of this study was to evaluate in chronic obstructive pulmonary disease patients the impact of asymptomatic/silent peripheral artery disease on maximal exercise capacity; the secondary aim was to search for predictors of peripheral artery disease. Methods We prospectively enrolled chronic obstructive pulmonary disease outpatients. Data on anthropometric characteristics, lung function, cardiopulmonary exercise test and ankle-brachial index were recorded...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28436583/physical-activity-and-exercise-for-chronic-pain-in-adults-an-overview-of-cochrane-reviews
#17
REVIEW
Louise J Geneen, R Andrew Moore, Clare Clarke, Denis Martin, Lesley A Colvin, Blair H Smith
BACKGROUND: Chronic pain is defined as pain lasting beyond normal tissue healing time, generally taken to be 12 weeks. It contributes to disability, anxiety, depression, sleep disturbances, poor quality of life, and healthcare costs. Chronic pain has a weighted mean prevalence in adults of 20%.For many years, the treatment choice for chronic pain included recommendations for rest and inactivity. However, exercise may have specific benefits in reducing the severity of chronic pain, as well as more general benefits associated with improved overall physical and mental health, and physical functioning...
April 24, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28436500/black-phosphorus-nanostructures-recent-advances-in-hybridization-doping-and-functionalization
#18
Wanying Lei, Gang Liu, Jin Zhang, Minghua Liu
Owing to its high charge-carrier mobility, tunable direct-bandgap and unique in-plane anisotropic structure, black phosphorus (BP), a rising star of post-graphene two-dimensional (2D) nanomaterials, has been intensively investigated since early 2014. To explore its full potential and push the limits, research into BP-based novel functional nanostructures (i.e., nanomaterials and nanodevices) by means of hybridization, doping, and functionalization is rapidly expanding. Indeed, the cutting-edge developments and applications of BP nanostructures have had a significant impact on a wide range of research areas, including field effect transistors, diodes, photodetectors, biomedicine, sodium-ion batteries, photocatalysis, electrocatalysis, memory devices, and more...
April 24, 2017: Chemical Society Reviews
https://www.readbyqxmd.com/read/28436356/association-between-natural-killer-cell-activity-and-prostate-cancer-a-pilot-study
#19
Jack Barkin, Roberto Rodriguez-Suarez, Katia Betito
INTRODUCTION: Natural killer (NK) cells play a significant role in tumor cell immunosurveillance. The association between the activity of NK cells and prostate cancer has previously been demonstrated using conventional research-based tests. MATERIALS AND METHODS: The aim of the present pilot study was to study the association between NK cell activity (NKA) and prostate cancer using a simple blood test. Subjects that had previously been selected for prostate biopsy underwent a blood test for NKA using an in vitro diagnostic device (IVDD) (NK Vue, ATGen Canada Inc...
April 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/28436177/limited-evidence-of-abnormal-intra-colonic-pressure-profiles-in-diverticular-disease-a-systematic-review
#20
REVIEW
R Jaung, J Robertson, G O'Grady, T Milne, D Rowbotham, I P Bissett
AIM: Abnormal colonic pressure profiles and high intraluminal pressures are postulated to contribute to the formation of sigmoid colon diverticulosis and the pathophysiology of diverticular disease (DD). This study aimed to review evidence for abnormal colonic pressure profiles in diverticulosis. METHOD: All published studies investigating colonic pressure in patients with diverticulosis were searched in three databases (MEDLINE, EMBASE, SCOPUS). No language restrictions were applied...
April 24, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
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