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https://www.readbyqxmd.com/read/28106238/choroidal-thickness-and-structural-glaucoma-parameters-in-glaucomatous-preperimetric-glaucomatous-and-healthy-eyes-using-swept-source-oct
#1
Handan Akil, Mayss Al-Sheikh, Khalil Ghasemi Falavarjani, Brian Francis, Vikas Chopra
PURPOSE: To evaluate choroidal thickness (CT) and its relationship with retinal nerve fiber layer (RNFL) and ganglion cell-inner plexiform layer thickness (GCIPLT) in glaucomatous, preperimetric glaucomatous, and healthy eyes using swept-source optical coherence tomography (SS-OCT). METHODS: Fifty eyes with primary open-angle glaucoma, 20 eyes with preperimetric glaucoma, and 20 age-matched healthy eyes were enrolled. Three-dimensional wide-field (12 × 9 mm) images were obtained using a SS-OCT instrument...
January 16, 2017: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/28099294/examination-of-pediatric-radiation-dose-delivered-after-cervical-spine-trauma
#2
Laura K Somppi, Kristin A Frenn, Anupam B Kharbanda
OBJECTIVES: Pediatric cervical spine injuries (CSIs) are rare but potentially fatal injuries. Plain radiographs (x-rays) and computed tomography (CT) are used to diagnose CSIs. Given concerns related to radiation exposure, the utility of x-rays in diagnosing CSIs compared with other forms of imaging must be examined. METHODS: Patients younger than 19 years presenting with possible CSI to an urban tertiary care hospital who received imaging for possible CSI between January 1, 2011, and December 31, 2013, were included...
January 17, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28095029/utilization-of-conventional-neuroimaging-following-youth-concussion
#3
Sean C Rose, Caroline E Schaffer, Julie A Young, Kelly A McNally, Anastasia N Fischer, Geoffrey L Heyer
BACKGROUND/OBJECTIVE: Conventional neuroimaging is not recommended for the routine diagnosis of concussion, but some patients with concussion undergo computed tomography (CT) or magnetic resonance imaging (MRI). The objective of this study was to explore the clinical factors that predict neuroimaging utilization in concussion. METHODS: Concussion-related CT and MRI data were analysed from 1953 patients, aged 10-19 years, who presented to a sports concussion clinic within 30 days of injury...
January 17, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28093866/advancing-clinical-and-translational-science
#4
EDITORIAL
John A Wagner
The vision for the 2015-2020 American Society for Clinical Pharmacology and Therapeutics (ASCPT) strategic plan is that ASCPT's influence and leadership make it the authority on the science and practice of translational medicine, building on a foundation of clinical pharmacology and therapeutics [http://www.ascpt.org/About-ASCPT/ASCPT-Strategic-Plan]. The vision for Clinical and Translational Science (CTS) is well-suited for ASCPT.(1) Our vision is to become the beacon and organizing principle for the field of translational medicine, as well as to provide a vehicle for ASCPT member publications...
January 16, 2017: Clinical and Translational Science
https://www.readbyqxmd.com/read/28093617/the-developing-temporal-bone-computed-tomography-measurements-and-assessment-of-suture-closure-from-birth-to-18%C3%A2-years-of-age
#5
P Paetz, G F Goetz, H Lanfermann, A M Giesemann
PURPOSE: To describe the normal CT appearance of the developing temporal bone in children from birth to 18 years of age. METHODS: Two hundred and six temporal bone CTs of children from 0.14 to 18.95 years were retrospectively selected and reviewed. Temporal bones were measured in a standardized slice orientation using the length of the basal turn of the cochlea, the length and width of the petrous bone, the coronal extent, trailing edge and anterior-posterior dimension of the temporal bone and the angle between petrous bone's length and the midsagittal line in the axial plane showing the basal turn of the cochlea in its greatest extent...
January 16, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28092090/prevalence-of-mucopolysaccharidosis-types-i-ii-and-vi-in-the-pediatric-and-adult-population-with-carpal-tunnel-syndrome-cts-retrospective-and-prospective-analysis-of-patients-treated-for-cts
#6
Mette Borch Nørmark, Nanna Kjaer, Allan Meldgaard Lund
BACKGROUND: We wanted to investigate whether the prevalence of mucopolysaccharidoses (MPS) I, II, and VI was higher than expected in a selected cohort of patients with carpal tunnel syndrome (CTS). CTS is a common finding in patients with MPS, and therefore we screened patients who had undergone surgery for CTS for undiagnosed MPS. PATIENTS AND METHODS: Patients who had been operated for CTS were found in databases from two hospitals. Furthermore, patients who had undergone surgery for CTS when under the age of 18 were retrieved from the National Patient Registry...
January 17, 2017: JIMD Reports
https://www.readbyqxmd.com/read/28091439/is-epineurectomy-necessary-in-the-surgical-management-of-carpal-tunnel-syndrome
#7
U Tiftikci, S Serbest
BACKGROUND: In this study, it was aimed to determine whether median nerve epineurectomy is beneficial in the surgical management of carpal tunnel syndrome (CTS). MATERIALS AND METHODS: The study enrolled 72 patients including 34 patients without epineurectomy (Group A) and 38 patients with epineurectomy (Group B). Surgery was performed in patients with severe electrodiagnostic CTS findings, CTS duration >1 year and flattening along with hypervascularization in median nerve...
February 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28090791/additive-value-of-otosclerosis-weighted-images-for-the-ct-diagnosis-of-fenestral-otosclerosis
#8
Koji Yamashita, Akio Hiwatashi, Osamu Togao, Masatoshi Kondo, Kazufumi Kikuchi, Takashi Inoguchi, Junki Maehara, Yusuke Kyuragi, Hiroshi Honda
Background Otosclerotic foci are usually seen as minute low-density lesions and this may be attributed to relatively low sensitivity on visual assessment using computed tomography (CT). Otosclerotic foci can be detected by using the accurate region of interest (ROI) setting, while small ROI settings by less-experienced radiologists may result in false negative findings. Purpose To evaluate the diagnostic ability of our proposed method ("otosclerosis-weighted" imaging [OWI]), which is based on reversing the density, compared with conventional CT (CCT) imaging alone...
January 1, 2017: Acta Radiologica
https://www.readbyqxmd.com/read/28089483/patterns-of-failure-after-radiotherapy-for-pediatric-patients-with-intracranial-ependymoma
#9
Fatima Tensaouti, Anne Ducassou, Léonor Chaltiel, Stéphanie Bolle, Xavier Muracciole, Bernard Coche-Dequeant, Claire Alapetite, Valérie Bernier, Line Claude, Stéphane Supiot, Aymeri Huchet, Christine Kerr, Elisabeth le Prisé, Anne Laprie
PURPOSE: To investigate the patterns of failure after radiotherapy for pediatric intracranial ependymoma and their correlation with dose parameters. METHODS: Between 2000 and 2013, 206 patients were treated in France. MRI scans at relapse were registered to the original planning CTs for topographic analysis of failure patterns. To compare relapse patients (RP) with non relapse patients (NRP), several dose parameters were derived from dose volume histograms. RESULTS: Over a median follow-up of 53...
January 12, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28088844/role-of-contrast-ct-for-the-diagnosis-and-the-prognosis-of-suspected-lvad-thrombosis
#10
Bill C Tran, Prabhjot S Nijjar
BACKGROUND: There is an urgent need for further studies evaluating the role of imaging modalities in the management of left ventricular assist device (LVAD) thrombosis. This study reviews the role of computed tomography (CT) in the diagnosis of suspected LVAD thrombosis. METHODS: All contrast chest CTs performed in patients with suspected LVAD thrombosis at the University of Minnesota between January 2008 and April 2014 were reviewed. Significant CT findings were identified, operative notes were reviewed, and patient outcomes were reported...
January 15, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28088718/highly-efficient-inactivation-of-bacteria-found-in-drinking-water-using-chitosan-bentonite-composites-modelling-and-breakthrough-curve-analysis
#11
Sarah C Motshekga, Suprakas Sinha Ray
Disinfection of bacterially-contaminated drinking water requires a robust and effective technique and can be achieved by using an appropriate disinfectant material. The advanced use of nanomaterials is observed as an alternative and effective way for the disinfection process and water treatment as a whole. Hence, the inactivation of Escherichia coli (E. coli) using chitosan-Bentonite (Cts-Bent) composites was studied in a fixed bed column. Cts-Bent composites were synthesized using in situ cross-linking method using Bent-supported silver and zinc oxide nanoparticles...
January 3, 2017: Water Research
https://www.readbyqxmd.com/read/28081489/protective-effect-of-chitosan-on-photosynthesis-and-antioxidative-defense-system-in-edible-rape-brassica-rapa-l-in-the-presence-of-cadmium
#12
Haiying Zong, Song Liu, Ronge Xing, Xiaolin Chen, Pengcheng Li
Chitosan (CTS) induces plant tolerance against several abiotic stresses, including salinity and drought exposure. However, the role of CTS in cadmium (Cd)-induced stress amelioration is largely unknown. In the present study, a hydroponic pot experiment was conducted to study the roles of CTS with different molecular weight (Mw) (10kDa,5kDa and 1kDa) in alleviating Cd toxicity in edible rape (Brassica rapa L .). The results showed that Cd stress significantly decreased plant growth, leaf chlorophyll contents and increased the malondialdehyde (MDA) level in rape leaves...
January 9, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28075034/abdominal-lean-muscle-is-associated-with-lower-mortality-among-kidney-waitlist-candidates
#13
Jayme E Locke, J Jeff Carr, Sangeeta Nair, James G Terry, Rhiannon D Reed, Grant D Smith, Dorry L Segev, Vineeta Kumar, Cora E Lewis
Morphometric assessments, such as muscle density and body fat distribution, have emerged as strong predictors of cardiovascular risk and post-operative morbidity and mortality. To date, no study has examined morphometric mortality risk prediction among kidney transplant (KT) candidates. KT candidates, waitlisted 2008-2009 were identified (n=96) and followed to the earliest of transplant, death, or administrative end of study. Morphometric measures, including abdominal adipose tissue, paraspinous and psoas muscle composition, and aortic calcification were measured from CTs...
January 11, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/28073765/tracing-a-path-to-the-past-exploring-the-use-of-commercial-credit-reporting-data-to-construct-residential-histories-for-epidemiologic-studies-of-environmental-exposures
#14
Susan Hurley, Andrew Hertz, David O Nelson, Michael Layefsky, Julie Von Behren, Leslie Bernstein, Dennis Deapen, Peggy Reynolds
Large-scale environmental epidemiologic studies often rely on exposure estimates based on linkage to residential addresses. This approach, however, is limited by the lack of residential histories typically available for study participants. Our objective was to evaluate the feasibility of using address data from LexisNexis (a division of RELX, Inc., Dayton, Ohio), a commercially available credit reporting company, to construct residential histories for participants in the California Teachers Study (CTS), a prospective cohort study initiated in 1995-1996 to study breast cancer (n = 133,479)...
January 9, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28073579/robustness-of-4d-optimized-scanned-carbon-ion-beam-therapy-against-interfractional-changes-in-lung-cancer
#15
Christian Graeff
BACKGROUND AND PURPOSE: Moving targets could be conformally treated with actively scanned carbon ion beams using 4D-optimization. As this heavily exploits 4D-CTs, an important question is whether the conformity also upholds in the context of interfractional changes, i.e. variable positioning, anatomy and breathing patterns. MATERIALS AND METHODS: In 4 lung cancer patients, 6 weekly 4D-CTs were available. 4D-CTs and their phases were non-rigidly registered to propagate contours and 4D-doses...
January 7, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28073516/early-diagnosis-of-systemic-amyloidosis-by-means-of-a-transverse-carpal-ligament-biopsy-carried-out-during-carpal-tunnel-syndrome-surgery
#16
Judit Fernández Fuertes, Óscar Rodríguez Vicente, Sergio Sánchez Herráez, Luis Rafael Ramos Pascua
INTRODUCTION AND OBJECTIVE: The systematic analysis of a carpal transverse ligament (CTL) sample obtained during routine carpal tunnel syndrome (CTS) surgery may constitute a method of early diagnosis for systemic amyloidosis. MATERIAL AND METHODS: Prospective study carried out on 147 consecutive CTL samples collected from patients intervened for CTS at the University Hospital of León from April 2006 to May 2007. In those cases in which amyloid deposition was observed in the CTL sample, the study was completed with a fine needle aspiration biopsy (FNAB) of the subcutaneous fascia, using the Red Congo stain in both cases...
January 7, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/28072673/the-use-of-ultrasound-measured-optic-nerve-sheath-diameter-to-predict-ventriculoperitoneal-shunt-failure-in-children
#17
Sophia D Lin, Kimberly R Kahne, Amira El Sherif, Kevin Mennitt, David Kessler, Mary J Ward, Shari L Platt
OBJECTIVE: The goal of this study was to assess the accuracy of ultrasound-measured optic nerve sheath diameter (ONSD) as a screen for ventriculoperitoneal shunt failure. METHODS: We prospectively enrolled a convenience sample of children presenting to the ED with suspected shunt failure. The ONSD was measured by ultrasound and compared with computed tomography/magnetic resonance imaging (CT/MRI) and neurosurgical impression. We defined shunt failure on ultrasound as an ONSD greater than 4...
January 9, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28069450/micromechanical-modeling-of-rate-dependent-behavior-of-connective-tissues
#18
A Fallah, M T Ahmadian, K Firozbakhsh, M M Aghdam
In this paper, a constitutive and micromechanical model for prediction of rate-dependent behavior of connective tissues (CTs) is presented. Connective tissues are considered as nonlinear viscoelastic material. The rate-dependent behavior of CTs is incorporated into model using the well-known quasi-linear viscoelasticity (QLV) theory. A planar wavy representative volume element (RVE) is considered based on the tissue microstructure histological evidences. The presented model parameters are identified based on the available experiments in the literature...
January 7, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28064196/understanding-interactions-among-cephalometrics-variables-during-growth-in-untreated-class-iii-subjects
#19
Pietro Auconi, Marco Scazzocchio, Guido Caldarelli, Michele Nieri, James A McNamara, Lorenzo Franchi
OBJECTIVE: The aim of the present study was to apply a computational method commonly used in data mining discipline, classification trees (CTs), to evaluate the growth features in untreated Class III subjects. MATERIALS AND METHODS: CT was applied to data from 91 untreated Class III subjects (48 females and 43 males) and compared with the results of discriminant analysis (DA). For all subjects, lateral cephalograms were available at T1 (mean age 10.4 ± 2.0 years) and at T2 (mean age 15...
January 7, 2017: European Journal of Orthodontics
https://www.readbyqxmd.com/read/28062302/calcitonin-typical-suppression-of-osteoclastic-activity-by-amphioxus-calcitonin-superfamily-peptides-and-insights-into-the-evolutionary-conservation-and-diversity-of-their-structures
#20
Toshio Sekiguchi, Akira Shiraishi, Honoo Satake, Kenji Kuwasako, Hiroki Takahashi, Masayuki Sato, Makoto Urata, Shuichi Wada, Masato Endo, Takahiro Ikari, Atsuhiko Hattori, Ajai K Srivastav, Nobuo Suzuki
Calcitonin (CT) is a hormone that decreases serum calcium level by suppressing osteoclastic activity in the vertebrate bone. In vertebrates, the structure-function relationship of CTs has been studied extensively. We recently identified three CT superfamily peptides, Bf-CTFP1 to 3, and clarified the molecular and functional characteristics of their receptor and receptor activity-modifying protein in amphioxus, Branchiostoma floridae. However, the CT activity of Bf-CTFPs has yet to be investigated. In the present study, a functional analysis of Bf-CTFPs was performed using goldfish scales having both osteoclasts and osteoblasts...
January 3, 2017: General and Comparative Endocrinology
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