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https://www.readbyqxmd.com/read/28337177/diversity-and-abundance-of-ice-nucleating-strains-of-pseudomonas-syringae-in-a-freshwater-lake-in-virginia-usa
#1
Renée B Pietsch, Boris A Vinatzer, David G Schmale
The bacterium Pseudomonas syringae is found in a variety of terrestrial and aquatic environments. Some strains of P. syringae express an ice nucleation protein (hereafter referred to as Ice+) allowing them to catalyze the heterogeneous freezing of water. Though P. syringae has been sampled intensively from freshwater sources in France, little is known about the genetic diversity of P. syringae in natural aquatic habitats in North America. We collected samples of freshwater from three different depths in Claytor Lake, Virginia, USA between November 2015 and June 2016...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28325318/preparation-and-characterization-of-amine-functional-nano-hydroxyapatite-chitosan-bionanocomposite-for-bone-tissue-engineering-applications
#2
Besir Hakan Atak, Berna Buyuk, Merve Huysal, Sevim Isik, Mehmet Senel, Wolfgang Metzger, Guven Cetin
In this study, three different types of scaffolds including a uniquely modified composite scaffold - namely chitosan (CTS), nano-hydroxyapatite/chitosan composite (CTS+nHAP), and amine group (NH2) modified nano-hydroxyapatite/chitosan composite (CTS+nHAP-NH2) scaffolds - were synthesized for bone tissue engineering (BTE) purposes. As results of the study, it was found that all scaffold types were biodegradable with CTS and CTS+nHAP scaffolds losing up to 15% of their initial weight, while the CTS+nHAP-NH2 scaffold showing 10% of weight loss after six weeks of lysozyme treatment...
May 15, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28320368/use-of-a-decision-aid-did-not-decrease-decisional-conflict-in-patients-with-carpal-tunnel-syndrome
#3
Hyun Sik Gong, Jin Woo Park, Young Ho Shin, Kahyun Kim, Kwan Jae Cho, Goo Hyun Baek
BACKGROUND: Although a model for shared decision-making is important for patient-centered care, decisional conflict can emerge when patients participate in the decision-making. A decision aid is proposed to provide information and to involve patients more comfortably in the decision-making process. We aimed to determine whether a decision aid helps patients with carpal tunnel syndrome (CTS) experience less decisional conflict regarding their decision-making for surgery. METHODS: Eighty patients with CTS were randomized into two groups...
March 21, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28316276/levosimendan-in-patients-with-left-ventricular-dysfunction-undergoing-cardiac-surgery
#4
Rajendra H Mehta, Jeffrey D Leimberger, Sean van Diepen, James Meza, Alice Wang, Rachael Jankowich, Robert W Harrison, Douglas Hay, Stephen Fremes, Andra Duncan, Edward G Soltesz, John Luber, Soon Park, Michael Argenziano, Edward Murphy, Randy Marcel, Dimitri Kalavrouziotis, Dave Nagpal, John Bozinovski, Wolfgang Toller, Matthias Heringlake, Shaun G Goodman, Jerrold H Levy, Robert A Harrington, Kevin J Anstrom, John H Alexander
Background Levosimendan is an inotropic agent that has been shown in small studies to prevent or treat the low cardiac output syndrome after cardiac surgery. Methods In a multicenter, randomized, placebo-controlled, phase 3 trial, we evaluated the efficacy and safety of levosimendan in patients with a left ventricular ejection fraction of 35% or less who were undergoing cardiac surgery with the use of cardiopulmonary bypass. Patients were randomly assigned to receive either intravenous levosimendan (at a dose of 0...
March 19, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28315442/adsorption-and-desorption-behaviors-of-cesium-on-rayon-fibers-coated-with-chitosan-immobilized-with-prussian-blue
#5
Duangkamol Dechojarassri, Shohei Asaina, Sahori Omote, Kensuke Nishida, Tetsuya Furuike, Hiroshi Tamura
Rayon fiber coated with chitosan (CTS) that contained immobilized Prussian blue (KFe) (KFe/CTS/rayon) were investigated for the removal of cesium ion (Cs(+)) from contaminated water. The morphology and mechanical strength of the fibers were observed using scanning electron microscopy (SEM) and a universal testing machine, respectively. The Cs(+) concentration was determined by inductively coupled plasma-atomic emission spectroscopy. SEM images revealed that the surface of the KFe/CTS/rayon fiber showed the most roughness...
March 14, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28306692/carpal-tunnel-syndrome-grading-using-high-resolution-ultrasonography
#6
Hala R El Habashy, Reem A El Hadidy, Sandra M Ahmed, Basma B El Sayed, Aya S Ahmed
PURPOSE: Carpal tunnel syndrome (CTS) is a common entrapment neuropathy of the wrist. The diagnosis of CTS has been a concern for physicians for a long time. The aim of this study is to evaluate the use of the median nerve (MN) cross-sectional area (CSA) in the wrist compared with the CSA in the forearm to grade the severity of CTS in Egyptian patients. METHODS: The CSAs of the MN in the wrist and forearm were measured in 72 wrists that were diagnosed with CTS via nerve conduction studies and 80 healthy wrists...
March 16, 2017: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/28306547/synthetic-ct-for-mri-based-liver-stereotactic-body-radiotherapy-treatment-planning
#7
Jeremy S Bredfeldt, Lianli Liu, Mary Feng, Yue Cao, James M Balter
A technique for generating MRI-derived synthetic CT volumes (MRCTs) is demonstrated in support of adaptive liver stereotactic body radiation therapy (SBRT). Under IRB approval, 16 subjects with hepatocellular carcinoma were scanned using a single MR pulse sequence (T1 Dixon). Air-containing voxels were identified by intensity thresholding on T1-weighted, water and fat images. The envelope of the anterior vertebral bodies was segmented from the fat image and fuzzy-C-means (FCM) was used to classify each non-air voxel as mid-density, lower-density, bone, or marrow in the abdomen, with only bone and marrow classified within the vertebral body envelope...
March 17, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28301320/analysis-of-growth-hormone-receptor-gene-expression-in-tall-and-short-stature-children
#8
Sara Pagani, Giorgio Radetti, Cristina Meazza, Mauro Bozzola
BACKGROUND: The majority of children who present for evaluation of tall stature fall under the diagnosis of constitutional tall stature (CTS). METHODS: To investigate mechanisms of tall stature, we evaluated serum IGF-I values and the expression of the GHR gene in the peripheral blood cells of 46 subjects with normal height, 38 with tall stature and 30 healthy children with short stature. RESULTS: Our results showed significantly lower IGF-I levels in children with short stature (-0...
March 16, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28300293/coronary-artery-calcification-is-common-on-nongated-chest-computed-tomography-imaging
#9
Revathi Balakrishnan, Brian Nguyen, Roy Raad, Robert Donnino, David P Naidich, Jill E Jacobs, Harmony R Reynolds
BACKGROUND: Coronary artery calcification as assessed by computed tomography (CT) is a validated predictor of cardiovascular risk, whether identified on a dedicated cardiac study or on a routine non-gated chest CT. The prevalence of incidentally detected coronary artery calcification on non-gated chest CT imaging and consistency of reporting have not been well characterized. HYPOTHESIS: Coronary calcification is present on chest CT in some patients not taking statin therapy and may be under-reported...
March 16, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28299455/use-of-palmitoylethanolamide-in-carpal-tunnel-syndrome-a-prospective-randomized-study
#10
Jordi Faig-Martí, Adriana Martínez-Catassús
BACKGROUND: Palmitoylethanolamide (PEA) is an endogenous fatty acid amide that has shown anti-inflammatory activity and neuroprotection and has been used for the treatment of compressive syndromes. The aim of this study is to investigate the clinical and electrophysiological effects of conservative treatment with PEA in low to moderate carpal tunnel syndrome (CTS). MATERIALS AND METHODS: A prospective double-blinded randomized study was performed on 61 patients with a clinical and electrophysiologically confirmed diagnosis of low and moderate CTS...
March 15, 2017: Journal of Orthopaedics and Traumatology: Official Journal of the Italian Society of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/28298847/subjective-symptoms-of-carpal-tunnel-syndrome-correlate-more-with-psychological-factors-than-electrophysiological-severity
#11
Firosh Khan, Abdulkhader Shehna, Sivaramakrishnan Ramesh, Kakkassery Sankaran Sandhya, Reji Paul
AIM: Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy and is one of the most common requests for electrodiagnosis. We aimed to note the relationship of subjective symptom severity of CTS, with objective electrophysiological severity and psychological status of patients. PATIENTS AND METHODS: One hundred and forty-four consecutive patients of CTS referred to neurophysiology laboratory of a tertiary care hospital over 1 year were prospectively studied...
January 2017: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/28297426/mri-geometric-distortion-impact-on-tangential-whole-breast-imrt
#12
Amy Walker, Peter Metcalfe, Gary Liney, Vikneswary Batumalai, Kylie Dundas, Carri Glide-Hurst, Geoff P Delaney, Miriam Boxer, Mei Ling Yap, Jason Dowling, David Rivest-Henault, Elise Pogson, Lois Holloway
The purpose of this study was to determine the impact of magnetic resonance imaging (MRI) geometric distortions when using MRI for target delineation and planning for whole-breast, intensity-modulated radiotherapy (IMRT). Residual system distortions and combined systematic and patient-induced distortions are considered. This retrospective study investigated 18 patients who underwent whole-breast external beam radiotherapy, where both CT and MRIs were acquired for treatment planning. Distortion phantoms were imaged on two MRI systems, dedicated to radiotherapy planning (a wide, closed-bore 3T and an open-bore 1T)...
September 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28297355/mr-image-based-synthetic-ct-for-imrt-prostate-treatment-planning-and-cbct-image-guided-localization
#13
Shupeng Chen, Hong Quan, An Qin, Seonghwan Yee, Di Yan
The purpose of this study was to propose and evaluate a method of creating a synthetic CT (S-CT) from MRI simulation for dose calculation and daily CBCT localization. A pair of MR and CT images was obtained in the same day from each of 10 prostate patients. The pair of MR and CT images was preregistered using the deformable image registration (DIR). Using the corresponding displacement vector field (atlas-DVF), the CT image was deformed to the MR image to create an atlas MR-CT pair. Regions of interest (ROI) on the atlas MR-CT pair were delineated and used to create atlas-ROI masks...
May 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28297330/using-daily-diagnostic-quality-images-to-validate-planning-margins-for-prostate-interfractional-variations
#14
Wen Li, Andrew Vassil, Andrew Godley, Lama Muhieddine Mossolly, Qingyang Shang, Ping Xia
The purpose of this study is to use the same diagnostic-quality verification and planning CTs to validate planning margin account for residual interfractional variations with image-guided soft tissue alignment of the prostate. For nine prostate cancer patients treated with IMRT to 78 Gy in 39 fractions, daily verification CT-on-rails images of the first seven and last seven fractions (n=126) were retrospectively selected for this study. On these images, prostate, bladder, and rectum were delineated by the same attending physician...
May 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28295825/effectiveness-of-manual-therapy-versus-surgery-in-pain-processing-due-to-carpal-tunnel-syndrome-a-randomized-clinical-trial
#15
C Fernández-de-Las-Peñas, J Cleland, M Palacios-Ceña, S Fuensalida-Novo, C Alonso-Blanco, J A Pareja, F Alburquerque-Sendín
BACKGROUND: People with carpal tunnel syndrome (CTS) exhibit widespread pressure pain and thermal pain hypersensitivity as a manifestation of central sensitization. The aim of our study was to compare the effectiveness of manual therapy versus surgery for improving pain and nociceptive gain processing in people with CTS. METHODS: The trial was conducted at a local regional Hospital in Madrid, Spain from August 2014 to February 2015. In this randomized parallel-group, blinded, clinical trial, 100 women with CTS were randomly allocated to either manual therapy (n = 50), who received three sessions (once/week) of manual therapies including desensitization manoeuvres of the central nervous system, or surgical intervention (n = 50) group...
March 14, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28294324/blocking-fibrotic-signaling-in-fibroblasts-from-patients-with-carpal-tunnel-syndrome
#16
REVIEW
Yoshiaki Yamanaka, Anne Gingery, Gosuke Oki, Tai-Hua Yang, Chunfeng Zhao, Peter C Amadio
Fibrosis of the subsynovial connective tissue (SSCT) in carpal tunnel syndrome (CTS) patients is increasingly recognized as an important aspect of CTS pathophysiology. In this study, we evaluated the effect of blocking profibrotic pathways in fibroblasts from the SSCT in CTS patients. Fibroblasts were stimulated with transforming growth factor β1 (TGF-β1), and then treated either with a specific fibrosis pathway inhibitor targeting TGF-β receptor type 1 (TβRI), platelet-derived growth factor receptor (PDGFR), epidermal growth factor receptor (EGFR) or vascular endothelial growth factor receptor (VEGFR)...
March 10, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28293773/malignancy-risk-estimation-of-screen-detected-nodules-at-baseline-ct-comparison-of-the-pancan-model-lung-rads-and-nccn-guidelines
#17
Sarah J van Riel, Francesco Ciompi, Colin Jacobs, Mathilde M Winkler Wille, Ernst Th Scholten, Matiullah Naqibullah, Stephen Lam, Mathias Prokop, Cornelia Schaefer-Prokop, Bram van Ginneken
OBJECTIVES: To compare the PanCan model, Lung-RADS and the 1.2016 National Comprehensive Cancer Network (NCCN) guidelines for discriminating malignant from benign pulmonary nodules on baseline screening CT scans and the impact diameter measurement methods have on performances. METHODS: From the Danish Lung Cancer Screening Trial database, 64 CTs with malignant nodules and 549 baseline CTs with benign nodules were included. Performance of the systems was evaluated applying the system's original diameter definitions: D(longest-C) (PanCan), D(meanAxial) (NCCN), both obtained from axial sections, and D(mean3D) (Lung-RADS)...
March 14, 2017: European Radiology
https://www.readbyqxmd.com/read/28291826/endothelial-progenitor-cells-in-chronic-obstructive-pulmonary-disease-and-emphysema
#18
Margaret F Doyle, Russell P Tracy, Megha A Parikh, Eric A Hoffman, Daichi Shimbo, John H M Austin, Benjamin M Smith, Katja Hueper, Jens Vogel-Claussen, Joao Lima, Antoinette Gomes, Karol Watson, Steven Kawut, R Graham Barr
Endothelial injury is implicated in the pathogenesis of COPD and emphysema; however the role of endothelial progenitor cells (EPCs), a marker of endothelial cell repair, and circulating endothelial cells (CECs), a marker of endothelial cell injury, in COPD and its subphenotypes is unresolved. We hypothesized that endothelial progenitor cell populations would be decreased in COPD and emphysema and that circulating endothelial cells would be increased. Associations with other subphenotypes were examined. The Multi-Ethnic Study of Atherosclerosis COPD Study recruited smokers with COPD and controls age 50-79 years without clinical cardiovascular disease...
2017: PloS One
https://www.readbyqxmd.com/read/28291745/iterative-framework-for-the-joint-segmentation-and-ct-synthesis-of-mr-images-application-to-mri-only-radiotherapy-treatment-planning
#19
Ninon Burgos, Filipa Guerreiro, Jamie McClelland, Benoit Presles, Marc Modat, Simeon Nill, David Dearnaley, Nandita deSouza, Uwe Oelfke, Antje-Christin Knopf, Sebastien Ourselin, M Jorge Cardoso
To tackle the problem of MRI-only radiotherapy treatment planning (RTP), we propose a multi-atlas information propagation scheme that jointly segments organs and generates pseudo CT data from structural MR images. As the performance of the method strongly depends on the quality of the atlas database composed of multiple sets of aligned MR, CT and segmented images, we also propose a robust way of registering atlas MR and CT images, which combines structure-guided registration, and CT and MR image synthesis. We first evaluated the proposed framework in terms of segmentation and CT synthesis accuracy on 15 subjects with prostate cancer...
March 14, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28291438/isokinetic-evaluation-of-wrist-muscle-strength-in-patients-of-carpal-tunnel-syndrome
#20
Mehmet Ağırman, Adnan Kara, Oğuz Durmuş, İlknur Saral, Engin Çakar
OBJECTIVES: This study aims to investigate the isokinetic characteristics of wrist strength in flexion, extension, supination, pronation, radial, and ulnar deviation in patients with moderate or severe carpal tunnel syndrome (CTS). PATIENTS AND METHODS: Thirteen patients (23 hands) (2 males, 11 females; mean age 45 years; range 29 to 60 years) with moderate or severe CTS were compared to six healthy control subjects (12 hands) (2 males, 4 females; mean age 41 years; range 27 to 63 years) in this study, which was conducted between January 2016 and April 2016...
April 2017: Eklem Hastalıkları Ve Cerrahisi, Joint Diseases & related Surgery
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