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https://www.readbyqxmd.com/read/29330235/primary-care-physician-perspectives-about-antipsychotics-and-other-medications-for-symptoms-of-dementia
#1
J William Kerns, Jonathan D Winter, Katherine M Winter, Terry Boyd, Rebecca S Etz
BACKGROUND: Guidelines, policies, and warnings have been applied to reduce the use of medications for behavioral and psychological symptoms of dementia (BPSD). Because of rare dangerous side effects, antipsychotics have been singled out in these efforts. However, antipsychotics are still prescribed "off label" to hundreds of thousands of seniors residing in nursing homes and communities. Our objective was to evaluate how and why primary-care physicians (PCPs) employ nonpharmacologic strategies and drugs for BPSD...
January 2018: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/29327970/it-is-electric-electroconvulsive-therapy-for-refractory-central-pain-and-comorbid-psychiatric-disease
#2
Jacob J Strand, Lindsay L Warner, Mihir M Kamdar, Alice W Flaherty, Vicki A Jackson
Central pain syndromes are a complex, diverse group of clinical conditions that are poorly understood. We present a patient with progressive, debilitating central pain and co-existing mood disorders that was refractory to multimodal pharmacologic and nonpharmacologic therapies, but that ultimately responded to electroconvulsive therapy (ECT). The patient described it at various times as her skin being "lit on fire," "stabbed," "squeezed like a boa constrictor," or itching unbearably. She underwent a course of three sequential ECT treatments during her hospitalization and it dramatically decreased her pain...
January 12, 2018: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/29324522/how-does-repetitive-transcranial-magnetic-stimulation-influence-the-brain-in-depressive-disorders-a-review-of-neuroimaging-magnetic-resonance-imaging-studies
#3
Simon Taïb, Christophe Arbus, Anne Sauvaget, Marie Sporer, Laurent Schmitt, Antoine Yrondi
OBJECTIVE: Repetitive transcranial magnetic stimulation (rTMS) is a nonpharmacological technique used to stimulate the brain. It is a safe and proven alternative tool to treat resistant major depressive disorders (MDDs). Neuroimaging studies suggest a wide corticolimbic network is involved in MDDs. We researched observable changes in magnetic resonance imaging induced by rTMS to clarify the operational mechanism. METHODS: A systematic search of the international literature was performed using PubMed and Embase, using papers published up to January 1, 2017...
January 11, 2018: Journal of ECT
https://www.readbyqxmd.com/read/29324501/nonpharmacologic-management-of-acute-singultus-hiccups
#4
Daniel S Orlovich, Jay B Brodsky, John G Brock-Utne
No abstract text is available yet for this article.
January 9, 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29313029/translation-in-cardiovascular-stents-and-occluders-from-biostable-to-fully-degradable
#5
REVIEW
Yingying Huang, Yee Shan Wong, Herr Cheun Anthony Ng, Freddy Y C Boey, Subbu Venkatraman
Cardiovascular disease is a major cause of morbidity and mortality, especially in developed countries. Most academic research efforts in cardiovascular disease management focus on pharmacological interventions, or are concerned with discovering new disease markers for diagnosis and monitoring. Nonpharmacological interventions with therapeutic devices, conversely, are driven largely by novel materials and device design. Examples of such devices include coronary stents, heart valves, ventricular assist devices, and occluders for septal defects...
June 2017: Bioengineering & Translational Medicine
https://www.readbyqxmd.com/read/29310552/prevention-of-acute-kidney-injury-in-children-undergoing-cardiac-surgery-a-narrative-review
#6
Esther Huimin Leow, Yoke Hwee Chan, Yong Hong Ng, Joel Kian Boon Lim, Masakazu Nakao, Jan Hau Lee
Children undergoing cardiac surgery are at risk of developing acute kidney injury (AKI). Preventing cardiac surgery-associated AKI (CS-AKI) is important as it is associated with increased early- and long-term mortality and morbidity. Targeting modifiable risk factors (eg, avoiding poor renal perfusion, nephrotoxic drugs, and fluid overload) reduces the risk of CS-AKI. There is currently no strong evidence for the routine use of pharmacological approaches (eg, aminophylline, dexmedetomidine, fenoldopam, and steroids) to prevent CS-AKI...
January 2018: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/29309818/nonpharmacologic-interventions-for-improving-sleep-disturbances-in-patients-with-lung-cancer-a-systematic-review-and-meta-analysis
#7
REVIEW
Dimitrios Papadopoulos, Apostolos Papadoudis, Maria Kiagia, Konstantinos Syrigos
CONTEXT: Lung cancer patients suffer from higher levels of sleep disturbances compared to other cancer patients and this leads to greater distress, poorer function and lower quality of life. Nonpharmacologic interventions have demonstrated improvements in the context of breast cancer but their efficacy in the lung cancer population is unclear. OBJECTIVES: The aim of this review was to determine the effects of any nonpharmacologic intervention on sleep quality of lung cancer patients...
January 5, 2018: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29300722/health-care-provider-counseling-for-physical-activity-or-exercise-among-adults-with-arthritis-united-states-2002-and-2014
#8
Jennifer M Hootman, Louise B Murphy, John D Omura, Teresa J Brady, Michael Boring, Kamil E Barbour, Charles G Helmick
Arthritis affects an estimated 54 million U.S. adults and, as a common comorbidity, can contribute arthritis-specific limitations or barriers to physical activity or exercise for persons with diabetes, heart disease, and obesity (1). The American College of Rheumatology's osteoarthritis management guidelines recommend exercise as a first-line, nonpharmacologic strategy to manage arthritis symptoms (2), and a Healthy People 2020 objective is to increase health care provider counseling for physical activity or exercise among adults with arthritis...
January 5, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29299961/erythromelalgia
#9
Peter Franz Klein-Weigel, Theresa Sophie Volz, Jutta Gisela Richter
Erythromelalgia is a rare syndrome characterized by the intermittent or, less commonly, by the permanent occurrence of extremely painful hyperperfused skin areas mainly located in the distal extremities. Primary erythromelalgia is nowadays considered to be a genetically determined neuropathic disorder affecting SCN9A, SCN10A, and SCN11A coding for NaV1.7, NaV1.8, and NaV1.9 neuronal sodium channels. Secondary forms might be associated with myeloproliferative disorders, connective tissue disease, cancer, infections, and poisoning...
January 4, 2018: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/29298078/management-of-menopause-symptoms-with-acupuncture-an-umbrella-systematic-review-and-meta-analysis
#10
Deanna Befus, Remy R Coeytaux, Karen M Goldstein, Jennifer R McDuffie, Megan Shepherd-Banigan, Adam P Goode, Andrzej Kosinski, Megan G Van Noord, Soheir S Adam, Varsha Masilamani, Avishek Nagi, John W Williams
OBJECTIVES: Vasomotor symptoms (VMSs) are the most common symptoms reported during menopause. Although hormone therapy is effective for reducing VMSs, its use is restricted in some women. Many women with VMSs thus seek nonhormonal, nonpharmacologic treatment options such as acupuncture. DESIGN: An umbrella systematic review (SR) was conducted, supplemented by a search of published randomized controlled trials (RCTs), that assessed the effectiveness of acupuncture for VMSs, health-related quality of life (HRQOL), and adverse effects of treatment in perimenopausal or postmenopausal women...
January 3, 2018: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/29296741/osteonecrosis-in-children-and-adolescents-with-acute-lymphoblastic-leukemia-a-therapeutic-challenge
#11
REVIEW
Michaela Kuhlen, Marina Kunstreich, Kathinka Krull, Roland Meisel, Arndt Borkhardt
Osteonecrosis (ON) represents one of the most common and debilitating sequelae of antileukemic treatment in children and adolescents with acute lymphoblastic leukemia (ALL). Systematic screening strategies can focus on early detection and intervention to prevent ON from progressing to stages associated with pain and functional impairment. These strategies hold promise for reducing ON-associated morbidity without the risk of impairing leukemia control. Herein, we critically reviewed clinical data on pharmacological, nonpharmacological/nonsurgical, and surgical (including cellular) treatment options for ON, which are covered in the literature and/or are conceivable based on the supposed underlying ON pathophysiology...
June 13, 2017: Blood Advances
https://www.readbyqxmd.com/read/29295033/alcohol-priming-and-attribution-of-blame-in-an-acquaintance-rape-vignette
#12
Elena V Stepanova, Amy L Brown
Research on nonpharmacological effects of alcohol shows that exposure to alcohol-related cues (i.e., alcohol priming) can increase behaviors associated with actual alcohol consumption. Attributions of responsibility to female victims in sexual assault scenarios are affected by whether or not alcohol was consumed by a victim and/or perpetrator. Victims often receive higher levels of blame if they consume alcohol prior to the assault. This work extends the research on nonpharmacological effects of alcohol into a novel domain of blame attribution toward rape victims...
December 1, 2017: Journal of Interpersonal Violence
https://www.readbyqxmd.com/read/29285767/opioid-neonatal-abstinence-syndrome-an-overview
#13
Scott L Wexelblatt, Jennifer M McAllister, Amy T Nathan, Eric S Hall
Opioid neonatal abstinence syndrome (NAS) refers to signs of withdrawal observed in infants experiencing intrauterine opioid exposures. Early identification of at-risk infants allows for the prompt initiation of nonpharmacologic supportive care. When withdrawal symptoms are severe despite these interventions, pharmacologic therapy including opioid weaning is initiated. Consistency with standardized nonpharmacologic approaches as well as stringent weaning protocols are important in minimizing the length of stay and length of pharmacologic treatment for these vulnerable patients...
December 29, 2017: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29284352/pharmacological-management-of-anticancer-agent-extravasation-a-single-institutional-guideline
#14
Jaime Kimmel, Patrick Fleming, Sandra Cuellar, Jennifer Anderson, Christina Mactal Haaf
Although the risk of extravasation of a chemotherapy (anticancer) medication is low, the complications associated with these events can have a significant impact on morbidity and health care costs. Institutions that administer anticancer agents should ideally have a current guideline on the proper management of the inadvertent administration of these toxic medications into tissues surrounding blood vessels. It is imperative that the health care team involved in administering drugs used to treat cancer be educated on the risk factors, preventative strategies and treatment of anticancer extravasations, as well as practice safe and proper administration techniques...
January 1, 2017: Journal of Oncology Pharmacy Practice
https://www.readbyqxmd.com/read/29282534/computerized-cognitive-training-in-prostate-cancer-patients-on-androgen-deprivation-therapy-a-pilot-study
#15
Lisa M Wu, Ali Amidi, Molly L Tanenbaum, Gary Winkel, Wayne A Gordon, Simon J Hall, Katrin Bovbjerg, Michael A Diefenbach
PURPOSE: Prostate cancer patients who have undergone androgen deprivation therapy (ADT) may experience cognitive impairment, yet there is an unmet need for nonpharmacological interventions to address cognitive impairment in this population. This study examines the feasibility, acceptability, and preliminary efficacy of a home-based computerized cognitive training (CCT) program to treat cancer-related cognitive impairment. METHODS: Sixty men who had received ≥ 3 months of ADT were screened for at least mild cognitive or neurobehavioral impairment and randomized to 8 weeks of CCT or usual care...
December 27, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29278601/shivering-treatments-for-targeted-temperature-management-a-review
#16
Akash Jain, Maria Gray, Stephanie Slisz, Joseph Haymore, Neeraj Badjatia, Erik Kulstad
BACKGROUND: Shivering is common during targeted temperature management, and control of shivering can be challenging if clinicians are not familiar with the available options and recommended approaches. PURPOSE: The purpose of this review was to summarize the most relevant literature regarding various treatments available for control of shivering and suggest a recommended approach based on latest data. METHODS: The electronic databases PubMed/MEDLINE and Google Scholar were used to identify studies for the literature review using the following keywords alone or in combination: "shivering treatment," "therapeutic hypothermia," "core temperature modulation devices," and "targeted temperature management...
December 22, 2017: Journal of Neuroscience Nursing: Journal of the American Association of Neuroscience Nurses
https://www.readbyqxmd.com/read/29276289/a-case-of-metronidazole-injection-infiltration-without-sequelae
#17
Andrew M North, Justin M Yee
Purpose: This report describes a case of metronidazole injection infiltration which contrasts the sole other case report in the literature at this time, as the patient described herein experienced mild signs and symptoms with prompt resolution and no significant sequelae. Summary: The patient experienced metronidazole injection infiltration during administration open to gravity via an 18-gauge peripheral catheter in the left brachial vein. The site was examined at bedside within approximately 30 minutes of the incident and was noted to be slightly edematous, erythemic, and painful in terms of a 5...
September 2017: Hospital Pharmacy
https://www.readbyqxmd.com/read/29275064/role-of-physical-activity-and-exercise-in-alleviating-cognitive-impairment-in-people-with-epilepsy
#18
Jane B Allendorfer, Ricardo M Arida
Many persons with epilepsy (PWE) experience problems with a wide range of cognitive functions, including learning, memory, attention, and executive control. These deficits in cognition result in diminished quality of life for PWE and are related to many factors, including the etiology of their epilepsy, recurrent seizures, side effects of antiseizure medications, or a combination of these factors. Various treatments to ameliorate cognitive deficits experienced by PWE have been implemented, although noninvasive and nonpharmacologic strategies may be more appealing options due to their relatively low cost, reduced risk of side effects, and/or reduced potential interactions with antiseizure medications...
December 20, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/29274291/enriched-physical-environment-reverses-spatial-cognitive-impairment-of-socially-isolated-appswe-ps1de9-transgenic-mice-before-amyloidosis-onset
#19
Min Cao, Pan-Pan Hu, Yan-Li Zhang, Yi-Xin Yan, Christopher B Shields, Yi-Ping Zhang, Gang Hu, Ming Xiao
AIMS: Social isolation increases the onset of Alzheimer's disease (AD). Environmental enrichment, a complicated social and physical construct, plays beneficial effects on brain plasticity and function. This study was designed to determine whether physical enrichment can reduce the deleterious consequences of social isolation on the onset of AD. METHODS: One-month-old APPswe/PS1dE9 transgenic AD model mice were singly housed in the enriched physical environment for 8 weeks and then received behavioral tests, neuropathological analyses, and Western blot of the hippocampus...
December 23, 2017: CNS Neuroscience & Therapeutics
https://www.readbyqxmd.com/read/29249621/leveraging-interactive-patient-care-technology-to-improve-pain-management-engagement
#20
Suma Rao-Gupta, David Kruger, Lonna D Leak, Lisa A Tieman, Renee C B Manworren
Most children experience pain in hospitals; and their parents report dissatisfaction with how well pain was managed. Engaging patients and families in the development and evaluation of pain treatment plans may improve perceptions of pain management and hospital experiences. The aim of this performance improvement project was to engage patients and families to address hospitalized pediatric patients' pain using interactive patient care technology. The goal was to stimulate conversations about pain management expectations and perceptions of treatment plan effectiveness among patients, parents, and health care teams...
December 14, 2017: Pain Management Nursing: Official Journal of the American Society of Pain Management Nurses
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