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Quantitative sensory testing

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https://www.readbyqxmd.com/read/28330489/profiling-intraoral-neuropathic-disturbances-following-lingual-nerve-injury-and-in-burning-mouth-syndrome
#1
Amely Hartmann, Robin Seeberger, Malte Bittner, Roman Rolke, Claudia Welte-Jzyk, Monika Daubländer
BACKGROUND: The aim of the study was to analyse intraoral neurophysiological changes in patients with unilateral lingual nerve lesions as well as patients with Burning Mouth Syndrome (BMS) by applying a standardized Quantitative Sensory Testing (QST) protocol. METHODS: The study included patients suffering from a peripheral lesion of the lingual nerve (n = 4), from BMS (n = 5) and healthy controls (n = 8). Neurophysiological tests were performed in the innervation areas of the tongue bilaterally...
March 23, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28328653/somatosensory-functions-in-survivors-of-critical-illness
#2
Philipp Baumbach, Theresa Götz, Albrecht Günther, Thomas Weiss, Winfried Meissner
OBJECTIVES: There is growing evidence for increased levels of pain and reduced health-related quality of life in survivors of critical illness. Recent studies showed marked small nerve fiber pathology in critically ill patients, which may contribute to chronic pain states and reduced physical recovery after ICU discharge. Primary objective of this study was the comparison of somatosensory functions between survivors of critical illness 6 months after ICU discharge and controls. In post hoc analyses, we aimed to identify associations between small fiber deficits, pain, health-related quality of life, and clinical data...
March 21, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28328646/sensory-characterization-of-odors-in-used-disposable-absorbent-incontinence-products
#3
Heléne Widén, Susanne Alenljung, Ulla Forsgren-Brusk, Gunnar Hall
PURPOSE: The objectives of this study were to characterize the odors of used incontinence products by descriptive analysis and to define attributes to be used in the analysis. A further objective was to investigate to what extent the odor profiles of used incontinence products differed from each other and, if possible, to group these profiles into classes. SUBJECTS AND SETTING: Used incontinence products were collected from 14 residents with urinary incontinence living in geriatric nursing homes in the Gothenburg area, Sweden...
March 21, 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28328574/the-long-term-reliability-of-static-and-dynamic-quantitative-sensory-testing-in-healthy-individuals
#4
Anna Marcuzzi, Paul J Wrigley, Catherine M Dean, Roger Adams, Julia M Hush
Quantitative sensory tests (QST) have been increasingly used to investigate alterations in somatosensory function in a wide range of painful conditions. The interpretation of these findings is based on the assumption that the measures are stable and reproducible. To date, reliability of QST has been investigated for short test-retest intervals. The aim of this study was to investigate the long-term reliability of a multimodal QST assessment in healthy people, with testing conducted on three occasions over 4-months...
March 21, 2017: Pain
https://www.readbyqxmd.com/read/28324985/a-novel-thermal-tactile-stimulator-device-for-quantitative-sensory-testing
#5
Umit Kursun, Olcay Kursun, Oleg V Favorov
This paper outlines the design and preliminary experimental results of a novel thermal stimulator device designed to measure, from some perspectives, brain health. The device delivers some thermal stimuli and asks the subject about his perception about them, thus checking the correctness of the perception and even the existence of certain perceptual illusions that would normally be present in healthy cortex and nervous system. This noninvasive sensory technology is cheap and easy to use, it has the potential to be used in telemonitoring systems and in empowering the individual to track his/her progression over time on the provided neuropathy tests...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28323720/neuroprognostication-after-cardiac-arrest-in-the-light-of-targeted-temperature-management
#6
Mauro Oddo, Hans Friberg
PURPOSE OF REVIEW: Delayed awakening after targeted temperature management (TTM) and sedation is frequent among cardiac arrest patients. Differentiating between prolonged coma and irreversible cerebral damage can be challenging, therefore the utilization of a multimodal approach is recommended by international guidelines. Here, we discuss indications and advantages/disadvantages of available modalities for coma prognostication and describe new tools to improve our accuracy for outcome prediction...
March 20, 2017: Current Opinion in Critical Care
https://www.readbyqxmd.com/read/28302148/thermal-quantitative-sensory-testing-in-healthy-dutch-children-and-adolescents-standardized-test-paradigm-and-dutch-reference-values
#7
Gerbrich E van den Bosch, Monique van Dijk, Dick Tibboel, Abraham J Valkenburg
BACKGROUND: Quantitative sensory testing (QST) is often used to measure children's and adults' detection- and pain thresholds in a quantitative manner. In children especially the Thermal Sensory Analyzer (TSA-II) is often applied to determine thermal detection and pain thresholds. As comparisons between studies are hampered by the different testing protocols used, we aimed to present a standard protocol and reference values for thermal detection- and pain thresholds in children. METHODS: Our standard testing protocol includes reaction time dependent and independent tests and takes about 14-18 min to complete...
March 16, 2017: BMC Pediatrics
https://www.readbyqxmd.com/read/28296936/spatial-analysis-improves-the-detection-of-early-corneal-nerve-fiber-loss-in-patients-with-recently-diagnosed-type-2-diabetes
#8
Dan Ziegler, Karsten Winter, Alexander Strom, Andrey Zhivov, Stephan Allgeier, Nikolaos Papanas, Iris Ziegler, Jutta Brüggemann, Bernd Ringel, Sabine Peschel, Bernd Köhler, Oliver Stachs, Rudolf F Guthoff, Michael Roden
Corneal confocal microscopy (CCM) has revealed reduced corneal nerve fiber (CNF) length and density (CNFL, CNFD) in patients with diabetes, but the spatial pattern of CNF loss has not been studied. We aimed to determine whether spatial analysis of the distribution of corneal nerve branching points (CNBPs) may contribute to improving the detection of early CNF loss. We hypothesized that early CNF decline follows a clustered rather than random distribution pattern of CNBPs. CCM, nerve conduction studies (NCS), and quantitative sensory testing (QST) were performed in a cross-sectional study including 86 patients recently diagnosed with type 2 diabetes and 47 control subjects...
2017: PloS One
https://www.readbyqxmd.com/read/28290294/behavior-of-yeast-inoculated-during-semi-dry-coffee-fermentation-and-the-effect-on-chemical-and-sensorial-properties-of-the-final-beverage
#9
Luciana Silva Ribeiro, Maria Gabriela da Cruz Pedrozo Miguel, Suzana Reis Evangelista, Pamela Mynsen Machado Martins, Joshua van Mullem, Maisa Honorio Belizario, Rosane Freitas Schwan
Pulped Mundo Novo and Ouro Amarelo coffee beans were inoculated with Saccharomyces cerevisiae (CCMA 0200 and CCMA 0543) during semi-dry coffee fermentation and compared with a non-inoculated control. Samples were collected throughout the fermentation process (12days) to evaluate the persistence of the inoculum by Real-Time quantitative PCR (qPCR). Also, the chemical composition of the beans was determined by HPLC and GC-MS and the roasted beans were sensorial evaluated using the cupping test. S. cerevisiae CCMA 0543 had an average population of 5...
February 2017: Food Research International
https://www.readbyqxmd.com/read/28289462/the-perception-of-low-salt-bread-among-preschool-children-and-the-role-of-educational-personnel-in-creating-a-positive-attitude-towards-reformulated-food
#10
Boris Kovac, Maja Knific
INTRODUCTION: The purpose of this study was to identify the possibility of unnoticed reduction in salt content of bread as a basic food in the diet of preschool children. The response of children to less salty bread and the role of teachers and teacher assistants in the introduction of novelties into children's nutrition ware studied. METHODS: Using hedonic sensory evaluation in the case of bread, the perception of salty taste and responses of preschool children to salt reduction were observed...
March 1, 2017: Zdravstveno Varstvo
https://www.readbyqxmd.com/read/28287532/dynamic-quantitative-sensory-testing-to-characterize-central-pain-processing
#11
Ian G Mackey, Eric A Dixon, Kevin Johnson, Jiang-Ti Kong
Central facilitation and modulation of incoming nociceptive signals play an important role in the perception of pain. Disruption in central pain processing is present in many chronic pain conditions and can influence responses to specific therapies. Thus, the ability to precisely describe the state of central pain processing has profound clinical significance in both prognosis and prediction. Because it is not practical to record neuronal firings directly in the human spinal cord, surrogate behavior tests become an important tool to assess the state of central pain processing...
February 16, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28280911/-physiology-of-the-scalp
#12
REVIEW
R Rukwied
BACKGROUND: Human scalp reveals a remarkable difference to hairy skin of other body regions. The structure of the scalp offers effective protection against water loss and contributes to thermoregulation due to significant vascularization. The scalp is innervated by the trigeminus nerve. OBJECTIVES: The majority of the population complain about "sensitive" scalp. However, sensory, regional, ethnic or pathologic parameters contributing to "sensitive" scalp are largely unknown...
March 9, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28271298/post-operative-orofacial-pain-temporomandibular-dysfunction-and-trigeminal-sensitivity-after-recent-pterional-craniotomy-preliminary-study
#13
Thiago Medina Brazoloto, Silvia Regina Dowgan Tesseroli de Siqueira, Pedro Augusto Sampaio Rocha-Filho, Eberval Gadelha Figueiredo, Manoel Jacobsen Teixeira, José Tadeu Tesseroli de Siqueira
BACKGROUND: Surgical trauma at the temporalis muscle is a potential cause of post-craniotomy headache and temporomandibular disorders (TMD). The aim of this study was to evaluate the prevalence of pain, masticatory dysfunction and trigeminal somatosensory abnormalities in patients who acquired aneurysms following pterional craniotomy. METHODS: Fifteen patients were evaluated before and after the surgical procedure by a trained dentist. The evaluation consisted of the (1) research diagnostic criteria for TMD, (2) a standardized orofacial pain questionnaire and (3) a systematic protocol for quantitative sensory testing (QST) for the trigeminal nerve...
March 7, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28248713/a-prospective-study-of-chronic-pain-after-thoracic-surgery
#14
Emine Ozgur Bayman, Kalpaj R Parekh, John Keech, Atakan Selte, Timothy J Brennan
BACKGROUND: The goal of this study was to detect the predictors of chronic pain at 6 months after thoracic surgery from a comprehensive evaluation of demographic, psychosocial, and surgical factors. METHODS: Thoracic surgery patients were enrolled 1 week before surgery and followed up 6 months postsurgery in this prospective, observational study. Comprehensive psychosocial measurements were assessed before surgery. The presence and severity of pain were assessed at 3 and 6 months after surgery...
March 1, 2017: Anesthesiology
https://www.readbyqxmd.com/read/28243447/using-in-vivo-corneal-confocal-microscopy-to-identify-diabetic-sensorimotor-polyneuropathy-risk-profiles-in-patients-with-type-1-diabetes
#15
Evan J H Lewis, Bruce A Perkins, Lief E Lovblom, Richard P Bazinet, Thomas M S Wolever, Vera Bril
OBJECTIVE: Diabetic sensorimotor peripheral neuropathy (DSP) is the most prevalent complication in diabetes mellitus. Identifying DSP risk is essential for intervening early in the natural history of the disease. Small nerve fibers are affected earliest in the disease progression and evidence of this damage can be identified using in vivo corneal confocal microscopy (IVCCM). RESEARCH DESIGN AND METHODS: We applied IVCCM to a cohort of 40 patients with type 1 diabetes to identify their DSP risk profile...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28238265/new-sweet-tasting-oleanane-type-triterpenoid-saponins-from-tugancao-derris-eriocarpa-how
#16
Hong-Xia Zhang, Guo Sun, Jian-Long Gu, Zhi-Zhi Du
With the aim to investigate the sweet-tasting compounds in Derris eriocarpa How (a substitute for licorice in "Zhuang" and "Dai" ethnopharmacy in Guangxi and Yunnan provinces of China) as well as to ascertain why the stem of D. eriocarpa can be used to substitute for licorice in the sweetness taste aspect, taste sensory-guided fractionation was conducted to isolate sweet constituents from the extract of D. eriocarpa. Four sweet-tasting triterpenoid saponins were obtained, including millettiasaponin A (1) and three new saponins named derrisaponins A-C (2-4)...
March 8, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28230397/weighted-integration-suggests-that-visual-and-tactile-signals-provide-independent-estimates-about-duration
#17
Danny M Ball, Derek H Arnold, Kielan Yarrow
Humans might possess either a single (amodal) internal clock or multiple clocks for different sensory modalities. Sensitivity could be improved by the provision of multiple signals. Such improvements can be predicted quantitatively, assuming estimates are combined by summation, a process described as optimal when summation is weighted in accordance with the variance associated with each of the initially independent estimates. This possibility was assessed for visual and tactile information regarding temporal intervals...
February 23, 2017: Journal of Experimental Psychology. Human Perception and Performance
https://www.readbyqxmd.com/read/28221302/diagnostic-criteria-for-small-fiber-neuropathy
#18
Derrick Blackmore, Zaeem A Siddiqi
OBJECTIVES: Despite its relative common occurrence, definitive diagnosis of small fiber neuropathy (SFN) remains problematic. In practice, patients with pain, numbness, and/or paresthesias in their lower limbs are diagnosed with SFN if found to have dissociated sensory loss in their feet, that is, impaired pinprick perception (PP) but relatively preserved vibration. We sought to assess the sensitivity and specificity of clinical examination and various diagnostic tools available for screening SFN...
March 2017: Journal of Clinical Neuromuscular Disease
https://www.readbyqxmd.com/read/28215248/quantitative-sensory-test-for-primary-restless-legs-syndrome-willis-ekbom-disease-using-the-current-perception%C3%A2-threshold-test
#19
Yong Won Cho, Min-Sung Kang, Keun Tae Kim, So Young Do, Jung-Geun Lim, So Young Lee, Gholam K Motamedi
BACKGROUND: Restless legs syndrome/Willis-Ekbom disease (RLS/WED) is a sensorimotor neurological disorder, and it is especially aggravated at night. The purpose of this study was to investigate the diurnal sensory dysfunction in primary RLS/WED using the current perception threshold (CPT) test, compared to healthy controls. METHODS: Thirty primary RLS/WED subjects and 30 healthy controls were enrolled. The severity of RLS/WED and sleep problems were evaluated in all subjects...
February 2017: Sleep Medicine
https://www.readbyqxmd.com/read/28191033/algorithm-and-software-to-automatically-identify-latency-and-amplitude-features-of-local-field-potentials-recorded-in-electrophysiological-investigation
#20
Maria Rubega, Claudia Cecchetto, Stefano Vassanelli, Giovanni Sparacino
BACKGROUND: Local field potentials (LFPs) evoked by sensory stimulation are particularly useful in electrophysiological research. For instance, spike timing and current transmembrane current flow estimated from LFPs recorded in the barrel cortex in rats and mice are exploited to investigate how the brain represents sensory stimuli. Recent improvements in microelectrodes technology enable neuroscientists to acquire a great amount of LFPs during the same experimental session, calling for algorithms for their quantitative automatic analysis...
2017: Source Code for Biology and Medicine
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