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https://www.readbyqxmd.com/read/28453646/protecting-confidentiality-in-cancer-registry-data-with-geographic-identifiers
#1
Mandi Yu, Jerome Phillip Reiter, Li Zhu, Benmei Liu, Kathleen A Cronin, Eric J Rocky Feuer
The National Cancer Institute's Surveillance, Epidemiology, and End Results Program releases research files of cancer registry data. These files include geography at the county level, but no finer. Access to finer geography, such as tract identifiers, would enable richer analyses, for example, examination of health disparities across neighborhoods. To date, tract identifiers are left off the research files because they could compromise the confidentiality of patients' identities. We present an approach to include tract identifiers based on multiply-imputed, synthetic data...
April 27, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28453412/identification-and-characterization-of-citrus-tristeza-virus-isolates-breaking-resistance-in-trifoliate-orange-in-california
#2
Raymond K Yokomi, Vijayanandraj Selvaraj, Yogita Maheshwari, Maria Saponari, Annalisa Giampetruzzi, Michela Chiumenti, Subhas Hajeri
Most Citrus tristeza virus (CTV) isolates in California are biologically mild and symptomless in commercial cultivars on CTV tolerant rootstocks. However, to better define California CTV isolates showing divergent serological and genetic profiles, selected isolates were subjected to deep sequencing of small RNAs. Full-length sequences were assembled, annotated and trifoliate orange resistance-breaking (RB) isolates of CTV were identified. Phylogenetic relationships based on their full genomes placed three isolates in the RB clade: CA-RB-115, CA-RB-AT25, and CA-RB-AT35...
April 28, 2017: Phytopathology
https://www.readbyqxmd.com/read/28453244/a-cap-on-medicaid-how-block-grants-per-capita-caps-and-capped-allotments-might-fundamentally-change-the-safety-net
#3
Haleigh Mager-Mardeusz, Cosima Lenz, Gerald F Kominski
Changing the Medicaid program is a top priority for the Republican party. Common themes from GOP proposals include converting Medicaid from a jointly financed entitlement benefit to a form of capped federal financing. While proponents of this reform argue that it would provide greater flexibility and a more predictable budget for state governments, serious consequences would likely result for Medicaid enrollees and state governments. Under all three scenarios promoted by Republicans--block grants, capped allotments, and per capita caps—most states would face increased costs...
April 2017: Policy Brief
https://www.readbyqxmd.com/read/28449292/oral-health-beliefs-knowledge-and-behaviors-in-northern-california-american-indian-and-alaska-native-mothers-regarding-early-childhood-caries
#4
Brenda Heaton, Andrew Crawford, Raul I Garcia, Michelle Henshaw, Christine A Riedy, Judith C Barker, Maureen A Wimsatt
OBJECTIVES: To assess the oral health beliefs, knowledge, and behaviors related to early childhood caries (ECC) risk in a convenience sample of American Indian and Alaska Native (AIAN) mothers residing in rural Northern California communities. METHODS: Fifty-three mothers of young children were recruited from three tribal communities in Northern California with the assistance of the California Rural Indian Health Board, Inc. and its California Tribal Epidemiology Center and Dental Support Center...
April 27, 2017: Journal of Public Health Dentistry
https://www.readbyqxmd.com/read/28449126/results-of-the-answer-trial-using-the-pulserider-for-the-treatment-of-broad-necked-bifurcation-aneurysms
#5
Alejandro M Spiotta, Colin P Derdeyn, Satoshi Tateshima, Jay Mocco, R Webster Crowley, Kenneth C Liu, Lee Jensen, Koji Ebersole, Alan Reeves, Demetrius K Lopes, Ricardo A Hanel, Eric Sauvageau, Gary Duckwiler, Adnan Siddiqui, Elad Levy, Ajit Puri, Lee Pride, Roberta Novakovic, M Imran Chaudry, Raymond D Turner, Aquilla S Turk
BACKGROUND: The safety and probable benefit of the PulseRider (Pulsar Vascular, Los Gatos, California) for the treatment of broad-necked, bifurcation aneurysms was studied in the context of the prospective, nonrandomized, single arm clinical trial-the Adjunctive Neurovascular Support of Wide-neck aneurysm Embolization and Reconstruction (ANSWER) Trial. OBJECTIVE: To present the results of the United States cases employing the PulseRider device as part of the ANSWER clinical trial...
April 25, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28448905/drug-use-generations-and-patterns-of-injection-drug-use-birth-cohort-differences-among-people-who-inject-drugs-in-los-angeles-and-san-francisco-california
#6
Ricky N Bluthenthal, Lynn Wenger, Daniel Chu, Philippe Bourgois, Alex H Kral
OBJECTIVES: A robust literature documents generational trends in drug use. We examined the implications of changing national drug use patterns on drug injection histories of diverse people who inject drugs (PWID). METHODS: Drug use histories were collected from 776 active PWID in 2011-13. Using descriptive statistics, we examine drug use initiation by year and birth cohort (BC) differences in drug first injected. A multivariate linear regression model of time to injection initiation ([TTII] (year of first injection minus year of first illicit drug use) was developed to explore BC differences...
April 19, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28448904/support-for-marijuana-legalization-in-the-us-state-of-washington-has-continued-to-increase-through-2016
#7
Meenakshi Sabina Subbaraman, William C Kerr
BACKGROUND: Support for the legalization of recreational marijuana continues to increase across the United States and globally. In 2016, recreational marijuana was legalized in the most populous US state of California, as well as three other states. The primary aim of this study was to examine trends in support for recreational marijuana legalization in Washington, a state which has had legal recreational marijuana for almost four years, using data collected over the four years post-legalization...
April 19, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28448781/assessment-of-clinical-pharmacy-interventions-to-reduce-outpatient-use-of-high-risk-medications-in-the-elderly
#8
Sarah C Weddle, A Shaun Rowe, Julie W Jeter, Rachel C Renwick, Shaunta' M Chamberlin, Andrea S Franks
BACKGROUND: Use of high-risk medications in the elderly (HRME) and drug-disease (Rx-DIS) interactions in the elderly, as defined by the Healthcare Effectiveness Data and Information Set (HEDIS) Measures, are significantly associated with mortality, hospital admission, and need for emergency care. No published studies to date evaluate interventions to reduce the use of HEDIS-defined HRME, although many studies have postulated a beneficial effect of such interventions. OBJECTIVE: To evaluate the effect of pharmacist interventions on use of HRME and Rx-DIS interactions in the outpatient elderly population...
May 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28448772/the-effect-of-a-federal-controlled-substance-act-schedule-change-on-hydrocodone-combination-products-claims-in-a-medicaid-population
#9
Stephanie Tran, Pavel Lavitas, Karen Stevens, Bonnie C Greenwood, Karen Clements, Caroline J Alper, Kimberly Lenz, Mylissa Price, Tasmina Hydery, Jennifer L Arnold, Mito Takeshita, Rachel Bacon, Justin P Peristere, Paul L Jeffrey
BACKGROUND: In 2012, hydrocodone combination products (HCPs) were the most prescribed medications in the United States. Under the Controlled Substance Act of 1970, hydrocodone alone was classified as a Schedule II drug, while HCPs were classified as Schedule III, indicating a lower risk for abuse and misuse. However, according to a Drug Enforcement Agency analysis, the addition of nonopioids has not been shown to diminish abuse potential of hydrocodone. In response to concerns for drug abuse and overdose, the Drug Enforcement Agency rescheduled HCPs to Schedule II in October 2014, with the intent of limiting overprescribing and increasing awareness of their abuse potential...
May 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28448771/geosmithia-associated-with-bark-beetles-and-woodborers-in-the-western-usa-taxonomic-diversity-and-vector-specificity
#10
Miroslav Kolařík, Jiri Hulcr, Ned Tisserat, Wilhelm De Beer, Martin Kostovčík, Zuzana Kolaříková, Steven J Seybold, David M Rizzo
Fungi in the genus Geosmithia (Ascomycota: Hypocreales) are frequent associates of bark beetles and woodborers that colonize hardwood and coniferous trees. One species, Geosmithia morbida, is an economically damaging invasive species. The authors surveyed the Geosmithia species of California and Colorado, USA, to (i) provide baseline data on taxonomy of Geosmithia and beetle vector specificity across the western USA; (ii) investigate the subcortical beetle fauna for alternative vectors of the invasive G. morbida; and (iii) interpret the community composition of this region within the emerging global biogeography of Geosmithia...
April 24, 2017: Mycologia
https://www.readbyqxmd.com/read/28448728/does-an-injection-of-adipose-derived-mesenchymal-stem-cells-loaded-in-fibrin-glue-influence-rotator-cuff-repair-outcomes-a-clinical-and-magnetic-resonance-imaging-study
#11
Yong Sang Kim, Chang Hun Sung, Sung Hoon Chung, Sang Joon Kwak, Yong Gon Koh
BACKGROUND: The mesenchymal stem cell (MSC)-based tissue engineering approach has been developed to improve the treatment of rotator cuff tears. Hypothesis/Purpose: The purpose was to determine the effect of an injection of adipose-derived MSCs loaded in fibrin glue during arthroscopic rotator cuff repair on clinical outcomes and to evaluate its effect on structural integrity using magnetic resonance imaging (MRI). The hypothesis was that the application of adipose-derived MSCs would improve outcomes after the surgical repair of a rotator cuff tear...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28447649/california-s-3-billion-bet-on-stem-cells-faces-final-test
#12
Amy Maxmen
No abstract text is available yet for this article.
April 26, 2017: Nature
https://www.readbyqxmd.com/read/28447646/a-130-000-year-old-archaeological-site-in-southern-california-usa
#13
Steven R Holen, Thomas A Deméré, Daniel C Fisher, Richard Fullagar, James B Paces, George T Jefferson, Jared M Beeton, Richard A Cerutti, Adam N Rountrey, Lawrence Vescera, Kathleen A Holen
The earliest dispersal of humans into North America is a contentious subject, and proposed early sites are required to meet the following criteria for acceptance: (1) archaeological evidence is found in a clearly defined and undisturbed geologic context; (2) age is determined by reliable radiometric dating; (3) multiple lines of evidence from interdisciplinary studies provide consistent results; and (4) unquestionable artefacts are found in primary context. Here we describe the Cerutti Mastodon (CM) site, an archaeological site from the early late Pleistocene epoch, where in situ hammerstones and stone anvils occur in spatio-temporal association with fragmentary remains of a single mastodon (Mammut americanum)...
April 26, 2017: Nature
https://www.readbyqxmd.com/read/28447370/vulnerability-to-forest-loss-through-altered-postfire-recovery-dynamics-in-a-warming-climate-in-the-klamath-mountains
#14
Alan J Tepley, Jonathan R Thompson, Howard E Epstein, Kristina J Anderson-Teixeira
In the context of ongoing climatic warming, certain landscapes could be near a tipping point where relatively small changes to their fire regimes or their postfire forest recovery dynamics could bring about extensive forest loss, with associated effects on biodiversity and carbon-cycle feedbacks to climate change. Such concerns are particularly valid in the Klamath Region of northern California and southwestern Oregon, where severe fire initially converts montane conifer forests to systems dominated by broadleaf trees and shrubs...
April 27, 2017: Global Change Biology
https://www.readbyqxmd.com/read/28446698/adaptation-to-a-latitudinal-thermal-gradient-within-a-widespread-copepod-species-the-contributions-of-genetic-divergence-and-phenotypic-plasticity
#15
Ricardo J Pereira, Matthew C Sasaki, Ronald S Burton
Understanding how populations adapt to heterogeneous thermal regimes is essential for comprehending how latitudinal gradients in species diversification are formed, and how taxa will respond to ongoing climate change. Adaptation can occur by innate genetic factors, by phenotypic plasticity, or by a combination of both mechanisms. Yet, the relative contribution of such mechanisms to large-scale latitudinal gradients of thermal tolerance across conspecific populations remains unclear. We examine thermal performance in 11 populations of the intertidal copepod Tigriopus californicus, ranging from Baja California Sur (Mexico) to British Columbia (Canada)...
April 26, 2017: Proceedings. Biological Sciences
https://www.readbyqxmd.com/read/28446628/plasma-ferritin-and-hepcidin-are-lower-at-4-months-postpartum-among-women-with-elevated-c-reactive-protein-or-%C3%AE-1-acid-glycoprotein
#16
Josh M Jorgensen, Zhenyu Yang, Bo Lönnerdal, Caroline J Chantry, Kathryn G Dewey
Background: Ferritin and hepcidin are markers of iron status that typically increase during inflammation or infection. The postpartum period is a physiologically unique life stage in which the relations between these proteins and other markers of inflammation have not been extensively studied.Objective: We aimed to determine whether 2 markers of inflammation [high-sensitivity C-reactive protein (CRP) and α1-acid glycoprotein (AGP)] were associated with ferritin or hepcidin in postpartum women in California...
April 26, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28446159/the-quality-of-medicaid-and-medicare-data-obtained-from-cms-and-its-contractors-implications-for-pharmacoepidemiology
#17
Charles E Leonard, Colleen M Brensinger, Young Hee Nam, Warren B Bilker, Geralyn M Barosso, Margaret J Mangaali, Sean Hennessy
BACKGROUND: Administrative claims of United States Centers for Medicare and Medicaid Services (CMS) beneficiaries have long been used in non-experimental research. While CMS performs in-house checks of these claims, little is known of their quality for conducting pharmacoepidemiologic research. We performed exploratory analyses of the quality of Medicaid and Medicare data obtained from CMS and its contractors. METHODS: Our study population consisted of Medicaid beneficiaries (with and without dual coverage by Medicare) from California, Florida, New York, Ohio, and Pennsylvania...
April 26, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28445797/development-of-a-clinically-actionable-incisional-hernia-risk-model-after-colectomy-using-the-healthcare-cost-and-utilization-project
#18
Jason M Weissler, Michael A Lanni, Jesse Y Hsu, Michael G Tecce, Martin J Carney, Rachel R Kelz, Justin P Fox, John P Fischer
BACKGROUND: Incisional hernia (IH) remains a persistent and burdensome complication following colectomy. Through individualized risk-assessment and prediction models, we aim to: 1) improve preoperative risk counseling for patients undergoing colectomy; 2) identify modifiable preoperative risk factors; and 3) encourage the utilization of evidence-based risk prediction instruments in the clinical setting. STUDY DESIGN: A retrospective review of the Healthcare Cost and Utilization Project (HCUP) data was conducted for all patients undergoing either open or laparoscopic colectomy as identified through the state inpatient databases (SID) of California, Florida and New York in 2009...
April 23, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28445775/changes-in-social-isolation-and-loneliness-following-total-hip-and-knee-arthroplasty-longitudinal-analysis-of-the-english-longitudinal-study-of-ageing-elsa-cohort
#19
Toby O Smith, Jack R Dainty, Alex Macgregor
OBJECTIVE: To determine the prevalence and change in social isolation and loneliness in people before and after THA and TKA in England. DESIGN: The English Longitudinal Study of Ageing dataset, a prospective study of community-dwelling older adults, was used to identify people who had undergone primary THA or TKA because of osteoarthritis. Social isolation was assessed using the ELSA Social Isolation Index. Loneliness was evaluated using the Revised University of California, Los Angeles (UCLA) Loneliness Scale...
April 23, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28445624/the-role-of-publicly-funded-family-planning-sites-in-health-insurance-enrollment
#20
Jennifer Yarger, Sara Daniel, M Antonia Biggs, Jan Malvin, Claire D Brindis
CONTEXT: Publicly funded family planning providers are well positioned to help uninsured individuals learn about health insurance coverage options and effectively navigate the enrollment process. Understanding how these providers are engaged in enrollment assistance and the challenges they face in providing assistance is important for maximizing their role in health insurance outreach and enrollment. METHODS: In 2014, some 684 sites participating in California's family planning program were surveyed about their involvement in helping clients enroll in health insurance...
April 26, 2017: Perspectives on Sexual and Reproductive Health
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