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https://www.readbyqxmd.com/read/28938748/random-start-ovarian-stimulation-for-fertility-preservation-appears-unlikely-to-delay-initiation-of-neoadjuvant-chemotherapy-for-breast-cancer
#1
Joseph M Letourneau, Nikita Sinha, Kaitlyn Wald, Eve Harris, Molly Quinn, Tal Imbar, Evelyn Mok-Lin, A Jo Chien, Mitchell Rosen
STUDY QUESTION: Is random start ovarian stimulation associated with delays in initiation of neoadjuvant chemotherapy for breast cancer? SUMMARY ANSWER: Among women who complete fertility preservation (FP) consultation, random start ovarian stimulation is unlikely to delay time to initiation of neoadjuvant chemotherapy start. WHAT IS KNOWN ALREADY: Neoadjuvant chemotherapy is now a widely accepted treatment modality for operable breast cancer and random start ovarian stimulation is an increasingly-utilized modality for FP...
October 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28937512/obstetricians-and-gynecologists-of-the-future-a-survey-of-medical-students-applying-to-residency
#2
Meredith J Alston, Amy Meg Autry, Sarah A Wagner, Abigail Winkel, Amanda A Allshouse, Alyssa Stephenson-Famy
OBJECTIVE: To understand the characteristics and career goals of medical students selecting a career in obstetrics and gynecology. METHODS: In 2015-2016, medical students invited for interviews for obstetrics and gynecology residency at the University of Colorado, University of Washington, University of California San Francisco, Loyola University, and New York University received a voluntary 20-item electronic survey regarding factors influencing their choice of medical specialty...
October 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28937458/transpedicular-corpectomy-and-cage-placement-in-the-treatment-of-traumatic-lumbar-burst-fractures
#3
Martin H Pham, Alexander Tuchman, Thomas C Chen, Frank L Acosta, Patrick C Hsieh, John C Liu
STUDY DESIGN: Retrospective review. OBJECTIVE: To review the feasibility of a posterior-only approach for instrumented reconstruction in lumbar burst fractures. BACKGROUND: Burst fractures of the lumbar spine have been treated through a variety of techniques, including anterior, posterior, or combined approaches. Here we review series of patients undergoing posterior-only transpedicular corpectomy with instrumented fusion for traumatic lumbar burst fracture...
October 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28936698/recommendations-for-mechanical-ventilation-of-critically-ill-children-from-the-paediatric-mechanical-ventilation-consensus-conference-pemvecc
#4
Martin C J Kneyber, Daniele de Luca, Edoardo Calderini, Pierre-Henri Jarreau, Etienne Javouhey, Jesus Lopez-Herce, Jürg Hammer, Duncan Macrae, Dick G Markhorst, Alberto Medina, Marti Pons-Odena, Fabrizio Racca, Gerhard Wolf, Paolo Biban, Joe Brierley, Peter C Rimensberger
PURPOSE: Much of the common practice in paediatric mechanical ventilation is based on personal experiences and what paediatric critical care practitioners have adopted from adult and neonatal experience. This presents a barrier to planning and interpretation of clinical trials on the use of specific and targeted interventions. We aim to establish a European consensus guideline on mechanical ventilation of critically children. METHODS: The European Society for Paediatric and Neonatal Intensive Care initiated a consensus conference of international European experts in paediatric mechanical ventilation to provide recommendations using the Research and Development/University of California, Los Angeles, appropriateness method...
September 22, 2017: Intensive Care Medicine
https://www.readbyqxmd.com/read/28936400/diminishing-use-of-liver-biopsy-among-liver-transplant-recipients-for-hepatitis-c
#5
Elizabeth Aby, Melissa A Jimenez, Jonathan F Grotts, Vatche Agopian, Samuel W French, Ronald W Busuttil, Sammy Saab
Background and Aims: Hepatitis C virus (HCV) cirrhosis is the leading indication for liver transplantation in the United States and recurrent HCV following liver transplantation is a major cause of allograft loss and mortality. Liver biopsies are commonly used to identify recurrent HCV and determine the need for antiviral therapy. The introduction of direct-acting antiviral agents (DAAs) has changed the management of recurrent HCV infection. This study aimed to describe the role of liver biopsies in liver transplant recipients with HCV after the introduction of DAAs...
September 28, 2017: Journal of Clinical and Translational Hepatology
https://www.readbyqxmd.com/read/28935553/prevalence-risk-factors-and-antimicrobial-susceptibility-test-of-staphylococcus-aureus-in-bovine-cross-breed-mastitic-milk-in-and-around-asella-town-oromia-regional-state-southern-ethiopia
#6
Befikadu Seyoum, Hailemariam Kefyalew, Birhanu Abera, Nejash Abdela
A cross sectional study was undertaken from November 2016 to March 2017 in and around Asella town, Oromia regional state, southern Ethiopia, to determine the prevalence, associated risk factors and antimicrobial susceptibility of Staphylococcus aureus, in Bovine cross breed mastitis milk. A total of 384 lactating dairy cows were screened for mastitis based on clinical examinations and California mastitis test (CMT). Out of 230 lactating crossbred cows with either clinical or subclinical mastitis examined for the involvement of Staphylococcus aureus...
September 18, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28935396/evaluation-of-familial-factors-in-a-mexican-population-based-setting-with-gastroschisis-further-evidence-for-an-underlying-genetic-susceptibility
#7
REVIEW
Victor M Salinas-Torres, Rafael A Salinas-Torres, Ricardo M Cerda-Flores, Laura E Martínez-de-Villarreal
PURPOSE: To evaluate the occurrence of gastroschisis attributable to familial factors in a Mexican population-based setting. METHODS: A descriptive study was performed among gastroschisis cases born from 2010 through 2016 at Tijuana General Hospital (Baja California, Mexico) to generate multigenerational pedigrees. RESULTS: There were 87 gastroschisis cases from 57,217 live births. Six probands (6.9%) had another affected family member. Two half-siblings, a set of monozygotic twins, a mother-and-daughter occurrence, a distant paternal cousin and a distant maternal uncle were identified...
September 1, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28935081/efficacy-and-safety-of-the-absorb-bioresorbable-vascular-scaffold-in-females-and-males-results-of-an-individual-patient-level-pooled-meta-analysis-of-randomized-controlled-trials
#8
Satya Shreenivas, Dean J Kereiakes, Stephen G Ellis, Runlin Gao, Takeshi Kimura, Yoshinobu Onuma, Karine Piard-Ruster, Yunlong Zhang, Kai Koo, Minh-Thien Vu, Patrick W Serruys, Gregg W Stone
OBJECTIVES: Because females are under-represented in coronary trials, this study sought to assess the relative safety and efficacy of Absorb bioresorbable vascular scaffold (BVS) (Abbott Vascular, Santa Clara, California) and the Xience everolimus-eluting stent in females compared with males. BACKGROUND: The Absorb everolimus-eluting BVS provides drug delivery and mechanical support similar to a metallic drug-eluting stent, followed by resorption and restoration of more normal vascular structure with the potential to improve late clinical outcomes...
September 25, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28935071/clinical-angiographic-and-procedural-correlates-of-acute-subacute-and-late-absorb-scaffold-thrombosis
#9
Stephen G Ellis, Giuseppe Steffenino, Dean J Kereiakes, Gregg W Stone, R J van Geuns, Alexandre Abizaid, Holger Nef, Bernardo Cortese, Luca Testa, Maurizio Menichelli, Corrado Tamburino, Tommaso Gori, Takeshi Kimura, Patrick W Serruys, Salvatore Brugaletta, Manel Sabaté, Run-Lin Gao
OBJECTIVES: The authors sought to identify and verify independent correlates of device thrombosis from an analysis of multicenter trials and registries. BACKGROUND: Recent analyses suggest an increased risk of device thrombosis with Absorb bioresorbable vascular scaffold (Abbott Vascular, Santa Clara, California) implantation compared with metallic drug-eluting stents, and data from moderate size studies suggest a risk relationship to vessel size and technique. METHODS: From 8,771 consecutively treated patients, 105 patients (1...
September 25, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28934673/an-analysis-of-chemicals-and-other-constituents-found-in-produced-water-from-hydraulically-fractured-wells-in-california-and-the-challenges-for-wastewater-management
#10
Emily A Chittick, Tanja Srebotnjak
As high-volume hydraulic fracturing (HF) has grown substantially in the United States over the past decade, so has the volume of produced water (PW), i.e., briny water brought to the surface as a byproduct of oil and gas production. According to a recent study (Groundwater Protection Council, 2015), more than 21 billion barrels of PW were generated in 2012. In addition to being high in TDS, PW may contain hydrocarbons, PAH, alkylphenols, naturally occurring radioactive material (NORM), metals, and other organic and inorganic substances...
September 18, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28934596/features-and-outcomes-of-methamphetamine-associated-pulmonary-arterial-hypertension
#11
Roham T Zamanian, Haley Hedlin, Paul Greuenwald, David M Wilson, Joshua I Segal, Michelle Jorden, Kristina Kudelko, Juliana Liu, Andrew Hsi, Allyson Rupp, Andrew J Sweatt, Rubin Tuder, Gerald J Berry, Marlene Rabinovitch, Ramona L Doyle, Vinicio De Jesus Perez, Steven M Kawut
RATIONALE: While amphetamines are recognized as "likely" agents to cause drugs and toxins associated pulmonary arterial hypertension (PAH), (meth)amphetamine associated PAH (Meth-APAH) has not been well described. OBJECTIVES: To prospectively characterize the clinical presentation, histopathology, and outcomes of Meth-APAH compared to those of idiopathic PAH (iPAH). METHODS AND MEASUREMENTS: We performed a prospective cohort study of Meth-APAH and iPAH patients presenting to the Stanford University Pulmonary Hypertension Program between 2003-2015...
September 21, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/28934260/characterization-of-the-nasal-and-oral-microbiota-of-detection-dogs
#12
Anitha Isaiah, Aline Rodrigues Hoffmann, Russ Kelley, Paul Mundell, Jörg M Steiner, Jan S Suchodolski
Little is known about physiological factors that affect the sense of olfaction in dogs. The objectives of this study were to describe the canine nasal and oral microbiota in detection dogs. We sought to determine the bacterial composition of the nasal and oral microbiota of a diverse population of detection canines. Nasal and oral swabs were collected from healthy dogs (n = 81) from four locations-Alabama, Georgia, California, and Texas. Nasal and oral swabs were also collected from a second cohort of detection canines belonging to three different detection job categories: explosive detection dogs (SP-E; n = 22), patrol and narcotics detection dogs (P-NDD; n = 15), and vapor wake dogs (VWD-E; n = 9)...
2017: PloS One
https://www.readbyqxmd.com/read/28934239/characterisation-of-north-american-brucella-isolates-from-marine-mammals
#13
Adrian M Whatmore, Claire Dawson, Jakub Muchowski, Lorraine L Perrett, Emma Stubberfield, Mark Koylass, Geoffrey Foster, Nicholas J Davison, Christine Quance, Inga F Sidor, Cara L Field, Judy St Leger
Extension of known ecological niches of Brucella has included the description of two novel species from marine mammals. Brucella pinnipedialis is associated predominantly with seals, while two major Brucella ceti clades, most commonly associated with porpoises or dolphins respectively, have been identified. To date there has been limited characterisation of Brucella isolates obtained from marine mammals outside Northern European waters, including North American waters. To address this gap, and extend knowledge of the global population structure and host associations of these Brucella species, 61 isolates from marine mammals inhabiting North American waters were subject to molecular and phenotypic characterisation enabling comparison with existing European isolates...
2017: PloS One
https://www.readbyqxmd.com/read/28934094/estimated-changes-in-life-expectancy-and-adult-mortality-resulting-from-declining-pm2-5-exposures-in-the-contiguous-united-states-1980-2010
#14
Neal Fann, Sun-Young Kim, Casey Olives, Lianne Sheppard
BACKGROUND: PM2.5 precursor emissions have declined over the course of several decades, following the implementation of local, state, and federal air quality policies. Estimating the corresponding change in population exposure and PM2.5-attributable risk of death prior to the year 2000 is made difficult by the lack of PM2.5 monitoring data. OBJECTIVES: We used a new technique to estimate historical PM2.5 concentrations, and estimated the effects of changes in PM2...
September 6, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28934093/combined-prenatal-pesticide-exposure-and-folic-acid-intake-in-relation-to-autism-spectrum-disorder
#15
Rebecca J Schmidt, Vladimir Kogan, Janie F Shelton, Lora Delwiche, Robin L Hansen, Sally Ozonoff, Claudia C Ma, Erin C McCanlies, Deborah H Bennett, Irva Hertz-Picciotto, Daniel J Tancredi, Heather E Volk
BACKGROUND: Maternal folic acid (FA) protects against developmental toxicity from certain environmental chemicals. OBJECTIVE: We examined combined exposures to maternal FA and pesticides in relation to autism spectrum disorder (ASD). METHODS: Participants were California children born from 2000-2007 who were enrolled in the Childhood Autism Risks from Genetics and the Environment (CHARGE) case-control study at age 2-5 y, were clinically confirmed to have ASD (n=296) or typical development (n=220), and had information on maternal supplemental FA and pesticide exposures...
September 8, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28933935/a-smartphone-application-to-reduce-time-to-notification-of-sexually-transmitted-infections
#16
Adam Carl Cohen, Frederick Zimmerman, Michael Prelip, Deborah Glik
OBJECTIVES: To measure whether the implementation of Healthvana-an online patient engagement platform and smartphone application-reduced the number of days between sexually transmitted infection (STI) testing, notification, and treatment at AIDS Healthcare Foundation (AHF) Wellness Centers. METHODS: We analyzed the retrospective data for 917 male clients who tested positive and received treatment for chlamydia, gonorrhea, or syphilis between January 1, 2014, and December 31, 2015...
September 21, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28933932/enrollment-in-california-s-medicaid-program-after-the-affordable-care-act-expansion
#17
Jing Wang, Amal N Trivedi
OBJECTIVES: To determine enrollment rates and predictors of enrollment for newly eligible low-income adults in California following the Affordable Care Act's (ACA's) Medicaid expansion. METHODS: We used data from the 2014 to 2015 California Health Interview Survey to examine post-ACA Medicaid enrollment rates and multivariable logistic regression to assess the association of demographic factors, income, and health with enrollment. RESULTS: We found a 78...
September 21, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28933886/mexican-origin-youth-substance-use-trajectories-associations-with-cultural-and-family-factors
#18
Rick A Cruz, Kevin M King, Molly Mechammil, Mayra Bámaca-Colbert, Richard W Robins
The current study identified alcohol and cannabis use trajectories among a sample of Mexican-origin youth and examined cultural and familial correlates from childhood to adolescence. Mexican-origin youth (N = 674) from Northern California were assessed annually from ages 10 to 17 (8 waves). Latent class growth modeling examined variability in developmental trajectories for last 3-month alcohol and cannabis use frequency. Analyses also examined between-trajectory differences in youth's cultural practices and values, family cultural conflict, general parent-child conflict, and parental monitoring at 4 time points from ages 10 to 16...
September 21, 2017: Developmental Psychology
https://www.readbyqxmd.com/read/28933320/neisseria-dumasiana-sp-nov-from-human-sputum-and-a-dog-s-mouth
#19
Danielle Wroblewski, Jocelyn Cole, Jana McGinnis, Maria Perez, Harriet Wilson, Lisa A Mingle, Kimberlee A Musser, William J Wolfgang
Three independent isolates of Gram-reaction-negative cocci collected from two New York State patients and a dog's mouth in California were subjected to a polyphasic analysis. The 16S rRNA gene sequence similarity among these isolates is 99.66 to 99.86 %. The closest species with a validly published name is Neisseria zoodegmatis (98.7 % 16S rRNA gene sequence similarity) with six additional species of the genus Neisseria with greater than 97 % similarity. Average nucleotide identity (ANI) and genome-to-genome distance calculator (GGDC 2...
September 21, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28932281/shoulder-specific-outcomes-1-year-after-nontraumatic-full-thickness-rotator-cuff-repair-a-systematic-literature-review-and-meta-analysis
#20
REVIEW
Navin Gurnani, Derek F P van Deurzen, Michel P J van den Bekerom
BACKGROUND: Nontraumatic full-thickness rotator cuff tears are commonly initially treated conservatively. If conservative treatment fails, rotator cuff repair is a viable subsequent option. The objective of the present meta-analysis is to evaluate the shoulder-specific outcomes one year after arthroscopic or mini-open rotator cuff repair of nontraumatic rotator cuff tears. METHODS: A literature search was conducted in PubMed and EMBASE within the period January 2000 to January 2017...
October 2017: Shoulder & Elbow
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