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https://www.readbyqxmd.com/read/28918359/major-depressive-disorder-and-anxiety-disorders-from-the-glial-perspective-etiological-mechanisms-intervention-and-monitoring
#1
REVIEW
Mari Sild, Edward S Ruthazer, Linda Booij
Despite intense ongoing research efforts, the etiology of psychiatric disorders remains incompletely understood. Among biological factors playing a role in Major Depressive Disorder (MDD) and Anxiety Disorders (ANX), emerging evidence points to the relevance of different types of glia cells and efficient neuron-glia interactions. Here, we review recent findings highlighting the involvement of central nervous system (CNS) glia in MDD and ANX etiology and treatment response. Additionally, several relatively underexplored topics will be discussed: 1) glial response to non-pharmacological therapies, 2) impact of early life adversity on glia, 3) influence of lifestyle factors on glia in the context of MDD and ANX, and 4) monitoring glial functions in patients...
September 13, 2017: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/28914061/mobile-applications-as-good-intervention-tools-for-individuals-with-depression
#2
Petra Marešová, Blanka Klímová, Kamil Kuča
At present mental disorders affect approximately 450 million people around the world. Depressive disorder is probably one of the most serious disorders and as a type of chronic disease, it represents a global threat and burdens economic and social systems of both individuals and governments worldwide. One of these most recent non-pharmacological approaches is also the so-called mHealth (mobile health), the use of mobile devices for the practice of medicine and public health, which proves to be effective particularly in the early stages of depression...
2017: Ceská a Slovenská Farmacie
https://www.readbyqxmd.com/read/28912904/fasciatherapy-and-reflexology-compared-to-hypnosis-and-music-therapy-in-daily-stress-management
#3
Bernard Payrau, Nadine Quere, Elisabeth Breton, Christine Payrau
BACKGROUND: Patients suffering from stress symptoms due to every-day life who are looking for a non-pharmacological response to their relief expectation are many. Furthermore, early reckoning of the day-to-day stress which may lead to clinical diagnosis is the best way of preventing the stress-related diseases. Among the many alternative medicinal options, there is little evidence that fasciatherapy (Fs) and reflexology (Rf) are effective in this field. PURPOSE: assess incidence of fasciatherapy Danis Bois Method (DBM) and of reflexology on patients' stress level in everyday-life, and provide a more informed choice among the numerous mind and body techniques by comparing them with hypnosis (Hp) and music therapy (Mt)...
September 2017: International Journal of Therapeutic Massage & Bodywork
https://www.readbyqxmd.com/read/28905362/transcutaneous-electrical-nerve-stimulation-tens-for-neuropathic-pain-in-adults
#4
REVIEW
William Gibson, Benedict M Wand, Neil E O'Connell
BACKGROUND: Neuropathic pain, which is due to nerve disease or damage, represents a significant burden on people and society. It can be particularly unpleasant and achieving adequate symptom control can be difficult. Non-pharmacological methods of treatment are often employed by people with neuropathic pain and may include transcutaneous electrical nerve stimulation (TENS). This review supersedes one Cochrane Review 'Transcutaneous electrical nerve stimulation (TENS) for chronic pain' (Nnoaham 2014) and one withdrawn protocol 'Transcutaneous electrical nerve stimulation (TENS) for neuropathic pain in adults' (Claydon 2014)...
September 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28902934/assessment-and-management-of-pain-in-newborns-hospitalized-in-a-neonatal-intensive-care-unit-a-cross-sectional-study
#5
Natália Pinheiro Braga Sposito, Lisabelle Mariano Rossato, Mariana Bueno, Amélia Fumiko Kimura, Taine Costa, Danila Maria Batista Guedes
Objective: to determine the frequency of pain, to verify the measures adopted for pain relief during the first seven days of hospitalization in the Neonatal Intensive Care Unit and to identify the type and frequency of invasive procedures to which newborns are submitted. Method: cross-sectional retrospective study. Out of the 188 hospitalizations occurred during the 12-month period, 171 were included in the study. The data were collected from the charts and the presence of pain was analyzed based on the Neonatal Infant Pain Scale and on nursing notes suggestions of pain...
September 12, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/28902932/non-pharmacological-interventions-to-promote-the-sleep-of-patients-after-cardiac-surgery-a-systematic-review
#6
Fernanda de Souza Machado, Regina Claudia da Silva Souza, Vanessa Brito Poveda, Ana Lucia Siqueira Costa
Objective: to analyze evidence available in the literature concerning non-pharmacological interventions that are effective to treat altered sleep patterns among patients who underwent cardiac surgery. Method: systematic review conducted in the National Library of Medicine-National Institutes of Health, Cochrane Central Register of Controlled Trials, Latin American and Caribbean Health Sciences Literature, Scopus, Embase, Cumulative Index to Nursing and Allied Health Literature and PsycINFO databases, and also grey literature...
September 12, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/28902899/selective-autonomic-stimulation-of-the-av-node-fat-pad-to-control-rapid-post-operative-atrial-arrhythmias
#7
Marco A Mercader, Dingchao He, Aditya C Sharma, Mark C Marchitto, Gregory Trachiotis, Gene A Bornzin, Richard Jonas, Jeffrey P Moak
Junctional ectopic tachycardia (JET) and atrial fibrillation (AF) occur in patients recovering from open-heart surgery (OHS). Pharmacologic treatment is used for the control of post-operative atrial arrhythmias (POAA), but is associated with side effects. There is a need for a reversible, modulated solution to rate control. We propose a non-pharmacologic technique that can modulate AV nodal conduction in a selective fashion. Ten mongrel dogs underwent OHS. Stimulation of the anterior right (AR) and inferior right (IR) fat pad (FP) was done using a 7-pole electrode...
2017: PloS One
https://www.readbyqxmd.com/read/28901992/european-guidelines-on-perioperative-venous-thromboembolism-prophylaxis-surgery-in-the-elderly
#8
Sibylle Kozek-Langenecker, Christian Fenger-Eriksen, Emmanuel Thienpont, Giedrius Barauskas
: The risk for postoperative venous thromboembolism (VTE) is increased in patients aged more than 70 years and in elderly patients presenting with co-morbidities, for example cardiovascular disorders, malignancy or renal insufficiency. Therefore, risk stratification, correction of modifiable risks and sustained perioperative thromboprophylaxis are essential in this patient population. Timing and dosing of pharmacoprophylaxis may be adopted from the non-aged population. Direct oral anti-coagulants are effective and well tolerated in the elderly; statins may not replace pharmacological thromboprophylaxis...
September 9, 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28898671/preterm-newborn-pain-research-review
#9
Tiffany Field
This narrative review is based on a literature search of PubMed and PsycINFO for research on preterm newborn pain published during the last ten years. The high prevalence of painful procedures being performed with preterm newborns without analgesia (79%), with a median of 75 painful procedures being received during hospitalization and as many as 51 painful procedures per day highlights the importance of this problem. This review covers the pain assessments that have been developed, the short-term effects of the painful procedures, the longer-term developmental outcomes and the pharmacological and alternative therapies that have been researched...
September 9, 2017: Infant Behavior & Development
https://www.readbyqxmd.com/read/28894475/news
#10
EDITORIAL
(no author information available yet)
The field of acute exacerbations (AEs) in chronic respiratory disease is challenging: definitions of AEs differ amongst the diseases and their severity has proven difficult to define. The Guest Editors of this Monograph tackle this challenging area by bringing together articles from internationally recognised experts in the field of AEs in chronic lung diseases. The book is separated into three sections: the first considers the definition, severity and consequences of exacerbations in each disease; the second looks at exacerbation triggers; and the third discusses the treatment and prevention of exacerbations using pharmacological and non-pharmacological interventions...
September 2017: Breathe
https://www.readbyqxmd.com/read/28891987/total-body-irradiation-mitigates-inflammation-and-extends-the-therapeutic-time-window-for-anti-ricin-antibody-treatment-against-pulmonary-ricinosis-in-mice
#11
Yoav Gal, Anita Sapoznikov, Reut Falach, Sharon Ehrlich, Moshe Aftalion, Chanoch Kronman, Tamar Sabo
Ricin, a highly toxic plant-derived toxin, is considered a potential weapon in biowarfare and bioterrorism due to its pronounced toxicity, high availability, and ease of preparation. Pulmonary exposure to ricin results in the generation of an acute edematous inflammation followed by respiratory insufficiency and death. Massive neutrophil recruitment to the lungs may contribute significantly to ricin-mediated morbidity. In this study, total body irradiation (TBI) served as a non-pharmacological tool to decrease the potential neutrophil-induced lung injury...
September 11, 2017: Toxins
https://www.readbyqxmd.com/read/28891795/-intravesical-botulinum-toxin-under-local-anestesia-as-ambulatory-procedure
#12
José Javier Fabuel Alcañiz, Laura Martínez Arcos, Miguel Jimenez Cidre, Francisco Javier Burgos Revilla
Bladder hyperactivity is described as the presence of "voiding urgency, generally associated with increased daytime frequency and nocturia, with or without urinary incontinence, in the absence of urinary tract infection or other obvious pathology". Onabotulinum toxin A (BTA) is a recommendable therapeutic option in case of failure, contraindication or refusal of the conservative therapy or other non-pharmacological therapies. The injection of BTA in the detrusor has been performed under local, regional or general anesthesia either in the conventional or major ambulatory surgery operative room or in the cystoscopy room...
September 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28890740/public-attitudes-towards-moral-enhancement-evidence-that-means-matter-morally
#13
Jona Specker, Maartje H N Schermer, Peter B Reiner
To gain insight into the reasons that the public may have for endorsing or eschewing pharmacological moral enhancement for themselves or for others, we used empirical tools to explore public attitudes towards these issues. Participants (N = 293) from the United States were recruited via Amazon's Mechanical Turk and were randomly assigned to read one of several contrastive vignettes in which a 13-year-old child is described as bullying another student in school and then is offered an empathy-enhancing program...
2017: Neuroethics
https://www.readbyqxmd.com/read/28890702/a-pilot-study-of-the-effects-of-mindfulness-based-stress-reduction-on-post-traumatic-stress-disorder-symptoms-and-brain-response-to-traumatic-reminders-of-combat-in-operation-enduring-freedom-operation-iraqi-freedom-combat-veterans-with-post-traumatic-stress
#14
James Douglas Bremner, Sanskriti Mishra, Carolina Campanella, Majid Shah, Nicole Kasher, Sarah Evans, Negar Fani, Amit Jasvant Shah, Collin Reiff, Lori L Davis, Viola Vaccarino, James Carmody
OBJECTIVE: Brain imaging studies in patients with post-traumatic stress disorder (PTSD) have implicated a circuitry of brain regions including the medial prefrontal cortex, amygdala, hippocampus, parietal cortex, and insula. Pharmacological treatment studies have shown a reversal of medial prefrontal deficits in response to traumatic reminders. Mindfulness-based stress reduction (MBSR) is a promising non-pharmacologic approach to the treatment of anxiety and pain disorders. The purpose of this study was to assess the effects of MBSR on PTSD symptoms and brain response to traumatic reminders measured with positron-emission tomography (PET) in Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) combat veterans with PTSD...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28890209/nursing-workload-and-adherence-to-non-pharmacological-measures-in-the-prevention-of-ventilator-associated-pneumonia-a-pilot-study
#15
R Jam, O Hernández, J Mesquida, C Turégano, E Carrillo, R Pedragosa, V Gómez, L Martí, J Vallés, P Delgado-Hito
OBJECTIVE: To analyse whether adherence to non-pharmacological measures in the prevention of ventilator-associated pneumonia (VAP) is associated with nursing workload. METHODS: A prospective observational study performed in a single medical-surgical ICU. Nurses in charge of patients under ventilator support were assessed. VARIABLES: knowledge questionnaire, application of non-pharmacological VAP prevention measures, and workload (Nine Equivalents of Nursing Manpower Use Score)...
September 7, 2017: Enfermería Intensiva
https://www.readbyqxmd.com/read/28884731/-optimization-of-the-algorithm-for-the-detection-and-the-differential-non-pharmacological-correction-of-the-risk-factors-and-the-preclinical-stages-of-atherosclerosis-at-the-level-of-the-health-resort-based-primary-care
#16
M A Vartazaryan, A T Bykov, A V Chernyshev, L S Khodasevich
This article presents the results of a comparative prospective study of 276 subjects at the age between 40 and 65 years presenting with risk factors (RF) of atherosclerosis and its preclinical stages (APC). All of them were reckoned to be at a moderate risk of developing APC based on the results of evaluation with the use of the SCORE scale which implied the necessity of their differential non-pharmacological treatment during a two-year period with the application of a variety of preventive therapeutic strategies...
2017: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/28882156/comparative-safety-and-efficacy-of-pharmacological-and-non-pharmacological-interventions-for-the-behavioral-and-psychological-symptoms-of-dementia-protocol-for-a-systematic-review-and-network-meta-analysis
#17
Jennifer Watt, Zahra Goodarzi, Andrea C Tricco, Areti-Angeliki Veroniki, Sharon E Straus
BACKGROUND: Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent in patients with dementia. Both pharmacological and non-pharmacological strategies are commonly used to treat these symptoms, but their comparative safety and efficacy is unknown. METHODS: We will conduct a systematic review of the published and unpublished literature to retrieve all articles pertaining to outcomes of safety and efficacy associated with pharmacological and non-pharmacological treatments of BPSD for patients living in the community and institutionalized care settings...
September 7, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28880416/the-effect-of-self-administered-superficial-local-hot-and-cold-application-methods-on-pain-functional-status-and-quality-of-life-in-primary-knee-osteoarthritis-patients
#18
Semra Aciksoz, Aygul Akyuz, Servet Tunay
AIMS AND OBJECTIVES: To investigate the effect of the self-administered superficial local hot and cold applications on pain, and the functional status and the quality of life in primary knee osteoarthritis patients. BACKGROUND: Superficial local hot and cold application is used as a non-pharmacological method for the treatment of knee osteoarthritis. However, various guidelines for the management of knee osteoarthritis have conflicting recommendation for hot and cold therapy...
September 7, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28880125/consensus-statement-of-the-international-summit-on-intellectual-disability-and-dementia-related-to-post-diagnostic-support
#19
Karen Dodd, Karen Watchman, Matthew P Janicki, Antonia Coppus, Claudia Gaertner, Juan Fortea, Flavia H Santos, Seth M Keller, Andre Strydom
OBJECTIVES: Post diagnostic support (PDS) has varied definitions within mainstream dementia services and different health and social care organizations, encompassing a range of supports that are offered to adults once diagnosed with dementia until death. METHOD: An international summit on intellectual disability and dementia held in Glasgow, Scotland in 2016 identified how PDS applies to adults with an intellectual disability and dementia. The Summit proposed a model that encompassed seven focal areas: post-diagnostic counseling; psychological and medical surveillance; periodic reviews and adjustments to the dementia care plan; early identification of behaviour and psychological symptoms; reviews of care practices and supports for advanced dementia and end of life; supports to carers/ support staff; and evaluation of quality of life...
September 7, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28878734/speech-and-voice-response-to-a-levodopa-challenge-in-late-stage-parkinson-s-disease
#20
Margherita Fabbri, Isabel Guimarães, Rita Cardoso, Miguel Coelho, Leonor Correia Guedes, Mario M Rosa, Catarina Godinho, Daisy Abreu, Nilza Gonçalves, Angelo Antonini, Joaquim J Ferreira
BACKGROUND: Parkinson's disease (PD) patients are affected by hypokinetic dysarthria, characterized by hypophonia and dysprosody, which worsens with disease progression. Levodopa's (l-dopa) effect on quality of speech is inconclusive; no data are currently available for late-stage PD (LSPD). OBJECTIVE: To assess the modifications of speech and voice in LSPD following an acute l-dopa challenge. METHOD: LSPD patients [Schwab and England score <50/Hoehn and Yahr stage >3 (MED ON)] performed several vocal tasks before and after an acute l-dopa challenge...
2017: Frontiers in Neurology
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