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Autism and environment

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https://www.readbyqxmd.com/read/29159578/assessing-quality-of-program-environments-for-children-and-youth-with-autism-autism-program-environment-rating-scale-apers
#1
Samuel L Odom, Ann Cox, John Sideris, Kara A Hume, Susan Hedges, Suzanne Kucharczyk, Evelyn Shaw, Brian A Boyd, Stephanie Reszka, Jennifer Neitzel
The purpose of this study was to examine the psychometric properties of the Autism Program Environment Rating Scale (APERS), an instrument designed to assess quality of program environments for students with autism spectrum disorder. Data sets from two samples of public school programs that provided services to children and youth with autism spectrum disorder were utilized. Cronbach alpha analyses indicated high coefficients of internal consistency for the total APERS and moderate levels for item domains for the first data set, which was replicated with the second data set...
November 20, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29139322/how-pupils-on-the-autism-spectrum-make-sense-of-themselves-in-the-context-of-their-experiences-in-a-mainstream-school-setting-a-qualitative-metasynthesis
#2
Emma I Williams, Kate Gleeson, Bridget E Jones
Evidence that interpersonal interactions and self-appraisal in social context are crucial in developing self-understanding raises concerns about how pupils with autism spectrum disorder make sense of themselves in school settings where many experience social marginalisation. Metasynthesis was used to systematically extract and integrate findings from qualitative studies examining the mainstream school experiences of these students. Synthesised findings identified three, intermeshing, aspects of experience which contribute to many pupils with autism spectrum disorder making sense of themselves as 'different' to typical peers in a negative way: difficulties linked to autism spectrum disorder; interpersonal relationships, particularly with peers; and accessibility of the school environment...
November 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/29138108/analysis-of-social-process-in-two-inbred-strains-of-male-mice-a-predominance-of-contact-based-investigation-in-balb-c-mice
#3
Hiroyuki Arakawa
Developing mouse models for social communication deficits requires a better understanding of the nature of social investigatory processes between mice. Mice use different investigatory strategies based on a possibility of contacts with social sources. A detailed investigation of contact distance revealed strain differences in behavioral strategy between two male inbred C57BL/6 (B6) and BALB/c (BALB) mouse strains. When direct physical contact with stimulus mice was restricted, BALB mice displayed lower social approaches than B6 mice, accompanied by heightened innate anxiety in an unfamiliar environment...
November 12, 2017: Neuroscience
https://www.readbyqxmd.com/read/29135429/laboratory-food-acceptance-in-children-with-autism-spectrum-disorder-compared-with-children-with-typical-development
#4
Michelle A Suarez
Studies using parent-report measures have described the high prevalence of food selectivity in children with autism spectrum disorder (ASD). However, few studies have documented food acceptance in a controlled laboratory environment. The objective of this study was to compare laboratory food acceptance in children with ASD with that of children with typical development (TD). In addition, the relationships between food acceptance and the child's age, sensory processing pattern, and autism severity were explored...
November 2017: American Journal of Occupational Therapy: Official Publication of the American Occupational Therapy Association
https://www.readbyqxmd.com/read/29134693/microglia-from-offspring-of-dams-with-allergic-asthma-exhibit-epigenomic-alterations-in-genes-dysregulated-in-autism
#5
Annie Vogel Ciernia, Milo Careaga, Janine M LaSalle, Paul Ashwood
Dysregulation in immune responses during pregnancy increases the risk of a having a child with an autism spectrum disorder (ASD). Asthma is one of the most common chronic diseases among pregnant women, and symptoms often worsen during pregnancy. We recently developed a mouse model of maternal allergic asthma (MAA) that induces changes in sociability, repetitive, and perseverative behaviors in the offspring. Since epigenetic changes help a static genome adapt to the maternal environment, activation of the immune system may epigenetically alter fetal microglia, the brain's resident immune cells...
November 14, 2017: Glia
https://www.readbyqxmd.com/read/29125691/virtual-environment-for-social-information-processing-assessment-of-children-with-and-without-autism-spectrum-disorders
#6
Nicole Russo-Ponsaran, Clark McKown, Jason Johnson, Jaclyn Russo, Jacob Crossman, Ilana Reife
Social information processing (SIP) skills are critical for developing and maintaining peer relationships. Building on existing assessment techniques, Virtual Environment for SIP (VESIP(TM) ), a simulation-based assessment that immerses children in social decision-making scenarios, was developed. This study presents preliminary evidence of VESIP's usefulness for measuring SIP skills in children with and without autism spectrum disorders (ASD). Twenty-one children with ASD and 29 control children participated...
November 10, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29102384/increased-stool-immunoglobulin-a-level-in-children-with-autism-spectrum-disorders
#7
Jiaxiu Zhou, Fusheng He, Feng Yang, Zheng Yang, Yingjun Xie, Shaoming Zhou, Jingwen Liang, Ruihuan Xu, Yan Wang, Hailiang Guo, Wenhao Zhou, Mingbang Wang
BACKGROUND: There are currently no effective treatments for the core symptoms of autism spectrum disorders (ASDs). However, alleviating gastrointestinal (GI) problems, which are prevalent in ASD patients, can significantly improve the core symptoms of autism. Previous studies have associated GI disorders in ASD patients with abnormal gut microbiota, although few disease-related microorganisms have been identified. Considering that the gut microbiome affects the intestinal immune system and the patient's behavior, and that immunoglobulin A (IgA) is the main antibody secreted by intestinal immune cells, we investigated stool IgA content as a means of understanding the gut immune status of ASD patients...
October 25, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29078024/don-t-ask-me-what-s-the-matter-ask-me-what-matters-acute-mental-health-facility-experiences-of-people-living-with-autism-spectrum-conditions
#8
Paul Maloret, Tricia Scott
BACKGROUND: This qualitative study explored how mental health inpatients with autistic spectrum conditions experience and cope with anxiety when admitted to an acute mental health inpatient facility in the UK. Anxiety is a common characteristic for people who live with autistic spectrum conditions and whilst a plethora of studies on anxiety in this population are published which correlate anxiety with mental health service experience, little is known about the actual triggers of anxiety and its manifestations...
October 27, 2017: Journal of Psychiatric and Mental Health Nursing
https://www.readbyqxmd.com/read/29073339/autism-and-primary-care-dentistry-parents-experiences-of-taking-children-with-autism-or-working-diagnosis-of-autism-for-dental-examinations
#9
Nicole Thomas, Sharon Blake, Christopher Morris, David R Moles
BACKGROUND: Accessing and receiving preventative dental treatment can be difficult for children with autism due to sensory processing disorders and/or challenging behaviours coupled with a reported reluctance by dentists to treat these children. AIM: To gather dental experiences of UK parents of children with autism or working diagnosis of autism and explore how they feel primary care dental services can be improved. DESIGN: A total of 17 parents of children with a diagnosis or working diagnosis of autism took part in semi-structured interviews...
October 26, 2017: International Journal of Paediatric Dentistry
https://www.readbyqxmd.com/read/29069906/parent-observed-thematic-data-on-quality-of-life-in-children-with-autism-spectrum-disorder
#10
Amy Epstein, Andrew Whitehouse, Katrina Williams, Nada Murphy, Helen Leonard, Elise Davis, Dinah Reddihough, Jenny Downs
Domains of quality of life in children with autism spectrum disorder have not previously been explored and there has been no quality of life measure developed for this population. Our study investigated parent observations to identify the domains important to children with autism spectrum disorder who also had an intellectual disability. In all, 21 parents (19 mothers, 2 fathers) of children with autism spectrum disorder (aged 6-17 years) participated in a qualitative study to discuss their child's quality of life...
October 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/29048365/integrating-autism-care-through-a-school-based-intervention-model-a-pilot-study
#11
Katherine Dang, Stephen Bent, Brittany Lawton, Tracy Warren, Felicia Widjaja, Michael G McDonald, Michael Breard, Whitney O'Keefe, Robert L Hendren
The purpose of this pilot study is to determine the feasibility of monitoring the progress of children with an autism spectrum disorder (ASD) both in school and at home to promote a school-based integrated care model between parents, teachers, and medical providers. This is a prospective cohort study. To monitor progress, outcome measures were administered via an online platform developed for caregivers and teachers of children (n = 30) attending a school specializing in neurodevelopmental disorders and using an integrated medical and education program...
October 19, 2017: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/29031410/harnessing-gut-microbes-for-mental-health-getting-from-here-to-there
#12
REVIEW
Annadora J Bruce-Keller, J Michael Salbaum, Hans-Rudolf Berthoud
There has been an explosion of interest in the study of microorganisms inhabiting the gastrointestinal tract (gut microbiota) and their impact on host health and physiology. Accumulating data suggest that altered communication between gut microbiota and host systems could participate in disorders such as obesity, diabetes mellitus, and autoimmune disorders as well as neuropsychiatric disorders, including autism, anxiety, and major depressive disorders. The conceptual development of the microbiome-gut-brain axis has facilitated understanding of the complex and bidirectional networks between gastrointestinal microbiota and their host, highlighting potential mechanisms through which this environment influences central nervous system physiology...
August 30, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/29021833/what-california-sea-lions-exposed-to-domoic-acid-might-teach-us-about-autism-lessons-for-predictive-and-preventive-medicine
#13
REVIEW
Garet Paul Lahvis
Autism spectrum disorder (ASD) shares many biological and behavioral similarities with the deleterious effects of domoic acid (DA) exposure. DA is produced by marine algae and most commonly by species of Pseudo-nitzschia. Humans and marine mammals can be exposed to DA when they consume whole fish or shellfish. The mammalian fetus is highly sensitive to the deleterious effects of DA exposure. Both ASD and exposures to toxic levels of DA feature repetitive behaviors, challenges with social interaction, and seizures...
September 2017: EPMA Journal
https://www.readbyqxmd.com/read/29020056/differences-in-change-blindness-to-real-life-scenes-in-adults-with-autism-spectrum-conditions
#14
Chris Ashwin, Sally Wheelwright, Simon Baron-Cohen
People often fail to detect large changes to visual scenes following a brief interruption, an effect known as 'change blindness'. People with autism spectrum conditions (ASC) have superior attention to detail and better discrimination of targets, and often notice small details that are missed by others. Together these predict people with autism should show enhanced perception of changes in simple change detection paradigms, including reduced change blindness. However, change blindness studies to date have reported mixed results in ASC, which have sometimes included no differences to controls or even enhanced change blindness...
2017: PloS One
https://www.readbyqxmd.com/read/28968035/-model-of-social-exclusion-of-the-elderly-people-in-siberian-regions
#15
S G Maximova, O E Noyanzina, D A Omelchenko
An article presents results of the construction and approbation of a theoretical model of social exclusion of population of elderly age groups in Siberian regions. It bases on the results of sociological research (2016) in three Russian regions: Altai region, Trans-Baikal region and Kemerovo oblast (n=779 age of respondents from 55 (women) and 60 (men) years and older). In theory, the model lays on the following: in is determined by economic (material) deprivation, deprivation of social rights (access to social institutes and services) and deprivation of security (safe environment), deprivation of social participation, cultural (normative) disintegration and social autism; the above named components are specific for the group of elderly people, that is a priori a high risk of exclusion; social exclusion, as a condition and situation of exclusion can be estimated straightly through the manifestation of its dimensions; the model has a one-way causality, i...
2017: Advances in Gerontology, Uspekhi Gerontologii
https://www.readbyqxmd.com/read/28948883/the-maternal-body-as-environment-in-autism-science
#16
Martine Lappé
Research on autism and environmental risk factors has expanded substantially in recent years. My analysis draws attention to the regimes of perceptibility that shape how the environment is materialized in post-genomic science. I focus on how more complex narratives of autism's causes and social anxieties surrounding child development have helped situate autism risk in women's bodies before and during pregnancy. This has resulted in what I call the maternal body as environment in autism science. I show that this figure involves three characteristics: the molecularization of the environment, an individualization of risk, and the internalization of responsibility...
October 2016: Social Studies of Science
https://www.readbyqxmd.com/read/28934093/combined-prenatal-pesticide-exposure-and-folic-acid-intake-in-relation-to-autism-spectrum-disorder
#17
Rebecca J Schmidt, Vladimir Kogan, Janie F Shelton, Lora Delwiche, Robin L Hansen, Sally Ozonoff, Claudia C Ma, Erin C McCanlies, Deborah H Bennett, Irva Hertz-Picciotto, Daniel J Tancredi, Heather E Volk
BACKGROUND: Maternal folic acid (FA) protects against developmental toxicity from certain environmental chemicals. OBJECTIVE: We examined combined exposures to maternal FA and pesticides in relation to autism spectrum disorder (ASD). METHODS: Participants were California children born from 2000-2007 who were enrolled in the Childhood Autism Risks from Genetics and the Environment (CHARGE) case-control study at age 2-5 y, were clinically confirmed to have ASD (n=296) or typical development (n=220), and had information on maternal supplemental FA and pesticide exposures...
September 8, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28921105/association-between-air-pollution-exposure-cognitive-and-adaptive-function-and-asd-severity-among-children-with-autism-spectrum-disorder
#18
Tara Kerin, Heather Volk, Weiyan Li, Fred Lurmann, Sandrah Eckel, Rob McConnell, Irva Hertz-Picciotto
Prenatal exposure to air pollution has been associated with autism spectrum disorder (ASD) risk but no study has examined associations with ASD severity or functioning. Cognitive ability, adaptive functioning, and ASD severity were assessed in 327 children with ASD from the Childhood Autism Risks from Genetics and the Environment study using the Mullen Scales of Early Learning (MSEL), the Vineland Adaptive Behavior Scales (VABS), and the Autism Diagnostic Observation Schedule calibrated severity score. Estimates of nitrogen dioxide (NO2), particulate matter (PM2...
September 18, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/28903621/virtual-environments-as-an-assessment-modality-with-pediatric-asd-populations-a-brief-report
#19
Tyler C Duffield, Thomas D Parsons, Allisen Landry, Shaza Karam, Tiffany Otero, Sarah Mastel, Trevor A Hall
Virtual environments (VEs) have demonstrated promise as a neuropsychological assessment modality and may be well suited for the evaluation of children suspected of having an autism spectrum disorder (ASD). Some recent studies indicate their potential for enhancing reliability, ecologically validity, and sensitivity over traditional neuropsychological evaluation measures. Although research using VEs with ASD is increasing to the degree that several reviews of the literature have been conducted, the reviews to date lack rigor and are not necessarily specific to cognitive or neuropsychological assessment as many focus on intervention...
September 13, 2017: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/28890420/perinatal-inflammation-and-adult-psychopathology-from-preclinical-models-to-humans
#20
REVIEW
Amaicha Mara Depino
Perinatal environment plays a crucial role in brain development and determines its function through life. Epidemiological studies and clinical reports link perinatal exposure to infection and/or immune activation to various psychiatric disorders. In addition, accumulating evidence from animal models shows that perinatal inflammation can affect various behaviors relevant to psychiatric disorders such as schizophrenia, autism, anxiety and depression. Remarkably, the effects on behavior and brain function do not always depend on the type of inflammatory stimulus or the perinatal age targeted, so diverse inflammatory events can have similar consequences on the brain...
September 7, 2017: Seminars in Cell & Developmental Biology
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