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Autism and environment

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https://www.readbyqxmd.com/read/29352834/confidence-in-communicating-with-patients-with-cancer-mediates-the-relationship-between-rehabilitation-therapists-autistic-like-traits-and-perceived-difficulty-in-communication
#1
Chinatsu Hayashibara, Masatoshi Inagaki, Maiko Fujimori, Yuji Higuchi, Masaki Fujiwara, Seishi Terada, Hitoshi Okamura, Yosuke Uchitomi, Norihito Yamada
OBJECTIVE: Recently, rehabilitation therapists have become involved in cancer rehabilitation; however, no communication skills training that increases the ability to provide emotional support for cancer patients has been developed for rehabilitation therapists. In addition, no study has examined associations between rehabilitation therapists' communication skills and their level of autistic-like traits (ALT), which are in-born characteristics including specific communication styles and difficulty communicating with patients...
January 21, 2018: Palliative & Supportive Care
https://www.readbyqxmd.com/read/29329511/classifying-and-characterizing-the-development-of-adaptive-behavior-in-a-naturalistic-longitudinal-study-of-young-children-with-autism
#2
Cristan Farmer, Lauren Swineford, Susan E Swedo, Audrey Thurm
BACKGROUND: Adaptive behavior, or the ability to function independently in ones' environment, is a key phenotypic construct in autism spectrum disorder (ASD). Few studies of the development of adaptive behavior during preschool to school-age are available, though existing data demonstrate that the degree of ability and impairment associated with ASD, and how it manifests over time, is heterogeneous. Growth mixture models are a statistical technique that can help parse this heterogeneity in trajectories...
January 5, 2018: Journal of Neurodevelopmental Disorders
https://www.readbyqxmd.com/read/29317608/epigenetics-and-cerebral-organoids-promising-directions-in-autism-spectrum-disorders
#3
REVIEW
Sheena Louise Forsberg, Mirolyuba Ilieva, Tanja Maria Michel
Autism spectrum disorders (ASD) affect 1 in 68 children in the US according to the Centers for Disease Control and Prevention (CDC). It is characterized by impairments in social interactions and communication, restrictive and repetitive patterns of behaviors, and interests. Owing to disease complexity, only a limited number of treatment options are available mainly for children that alleviate but do not cure the debilitating symptoms. Studies confirm a genetic link, but environmental factors, such as medications, toxins, and maternal infection during pregnancy, as well as birth complications also play a role...
January 10, 2018: Translational Psychiatry
https://www.readbyqxmd.com/read/29307038/an-evaluation-of-behavioral-skills-training-for-teaching-caregivers-how-to-support-social-skill-development-in-their-child-with-autism-spectrum-disorder
#4
Mahfuz Hassan, Andrea Simpson, Katey Danaher, James Haesen, Tanya Makela, Kendra Thomson
Limited research has explored how to best train caregivers to support their child with autism spectrum disorder (ASD) despite caregivers being well suited to promote generalization and maintenance of their child's skills in the natural environment. Children with ASD have been shown to benefit from social skill training, which is not always conducted in the natural context. This research examined the efficacy of behavioral skills training (BST) with, and without in situ training (IST), for teaching caregivers how to also use BST to support their child's context-specific social skills...
January 6, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29289663/identification-of-the-antigenic-epitopes-of-maternal-autoantibodies-in-autism-spectrum-disorders
#5
Elizabeth Edmiston, Karen L Jones, Tam Vu, Paul Ashwood, Judy Van de Water
Several groups have described the presence of fetal brain-reactive maternal autoantibodies in the plasma of some mothers whose children have autism spectrum disorder (ASD). We previously identified seven autoantigens targeted by these maternal autoantibodies, each of which is expressed at significant levels in the developing brain and has demonstrated roles in typical neurodevelopment. To further understand the binding repertoire of the maternal autoantibodies, as well as the presence of any meaningful differences with respect to the recognition and binding of these ASD- specific autoantibodies to each of these neuronal autoantigens, we utilized overlapping peptide microarrays incubated with maternal plasma samples obtained from the Childhood Autism Risk from Genetics and Environment (CHARGE) Study...
December 28, 2017: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/29280714/specific-sensory-techniques-and-sensory-environmental-modifications-for-children-and-youth-with-sensory-integration-difficulties-a-systematic-review
#6
Stefanie C Bodison, L Diane Parham
This systematic review examined the effectiveness of specific sensory techniques and sensory environmental modifications to improve participation of children with sensory integration (SI) difficulties. Abstracts of 11,436 articles published between January 2007 and May 2015 were examined. Studies were included if designs reflected high levels of evidence, participants demonstrated SI difficulties, and outcome measures addressed function or participation. Eight studies met inclusion criteria. Seven studies evaluated effects of specific sensory techniques for children with autism spectrum disorder (ASD) or attention deficit hyperactivity disorder: Qigong massage, weighted vests, slow swinging, and incorporation of multisensory activities into preschool routines...
January 2018: American Journal of Occupational Therapy: Official Publication of the American Occupational Therapy Association
https://www.readbyqxmd.com/read/29249827/schizophrenia-risk-and-urban-birth-are-associated-with-proteomic-changes-in-neonatal-dried-blood-spots
#7
Jason D Cooper, Sureyya Ozcan, Renee M Gardner, Nitin Rustogi, Susanne Wicks, Geertje F van Rees, F Markus Leweke, Christina Dalman, Håkan Karlsson, Sabine Bahn
In the present study, we tested whether there were proteomic differences in blood between schizophrenia patients after the initial onset of the disorder and controls; and whether those differences were also present at birth among neonates who later developed schizophrenia compared to those without a psychiatric admission. We used multiple reaction monitoring mass spectrometry to quantify 77 proteins (147 peptides) in serum samples from 60 first-onset drug-naive schizophrenia patients and 77 controls, and 96 proteins (152 peptides) in 892 newborn blood-spot (NBS) samples collected between 1975 and 1985...
December 18, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/29248917/the-home-literacy-environment-of-preschool-age-children-with-autism-or-down-syndrome
#8
Marleen Westerveld, Anne K van Bysterveldt
AIMS: This exploratory study investigated if there were differences in the home literacy environment of preschool children on the autism spectrum and preschool children with Down syndrome to determine if the home literacy environment may potentially be associated with strengths or weaknesses in children's social communication skills. METHODS: A total of 111 parents of preschoolers with identified disabilities completed a home literacy questionnaire. RESULTS: Results indicated that both groups of parents started reading to their children at an early age and owned at least 25 children's books...
2017: Folia Phoniatrica et Logopaedica
https://www.readbyqxmd.com/read/29239739/endophenotypes-a-conceptual-link-between-anorexia-nervosa-and-autism-spectrum-disorder
#9
Z C Zhou, D B McAdam, D R Donnelly
The paper, by translating the concept and the two models of endophenotype (EP), strengthens the hypothesis that there exists a linkage between anorexia nervosa (AN) and autism spectrum disorder (ASD). Specifically, the paper synthesizes empirical research that supported the idea that individuals with AN and individuals with ASD share similarities with respect to their neurocognitive EPs and temperament EPs. The paper then introduces an innovative structure to emphasize the subtle difference between neurocognitive EPs and temperament EPs in relation to AN and ASD...
November 24, 2017: Research in Developmental Disabilities
https://www.readbyqxmd.com/read/29237275/an-exploratory-longitudinal-study-of-social-and-language-outcomes-in-children-with-autism-in-bilingual-home-environments
#10
Vanessa Zhou, Jeffrey A Munson, Jessica Greenson, Yan Hou, Sally Rogers, Annette M Estes
Little is known about outcomes of early intervention for children with autism spectrum disorder reared in bilingual homes. There are concerns that social communication deficits among children with autism spectrum disorder may reduce the developmental benefits of early intervention for children with autism spectrum disorder raised in bilingual environments. We conducted an exploratory analysis of cross-sectional and longitudinal data from a larger study to explore associations between home language environment and language ability and social skills in response to early autism spectrum disorder intervention...
December 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/29228780/vocalizations-of-minimally-verbal-children-with-autism-spectrum-disorder-across-the-school-year
#11
Moon Young Savana Bak, Joshua B Plavnick, Sarah M Byrne
Little is known about the language trajectories of minimally verbal school-aged children with autism spectrum disorders. The present investigation conducted observations across two elementary schools over an entire school year to analyze the vocal language development of nine minimally verbal children with autism spectrum disorder between the ages of 6 and 10 years, and their educational service providers. A Language Environment Analysis™ device automatically recorded and disaggregated over 743 h of data on child vocalizations, and vocal interactions with adults...
December 1, 2017: Autism: the International Journal of Research and Practice
https://www.readbyqxmd.com/read/29227584/npas4-deficiency-and-prenatal-stress-interact-to-affect-social-recognition-in-mice
#12
Kelsey Heslin, Laurence Coutellier
Neurodevelopmental disorders such as autism spectrum disorders and schizophrenia have an expansive array of reported genetic and environmental contributing factors. However, none of these factors alone can account for a substantial proportion of cases of either disorder. Instead, many gene-by-environment interactions are responsible for neurodevelopmental disturbances that lead to these disorders. The current experiment used heterozygous knock-out mice to examine a potential interaction between two factors commonly linked to neurodevelopmental disorders and cognitive deficit: imbalanced excitatory/inhibitory signaling in the cortex and prenatal stress (PNS) exposure...
December 11, 2017: Genes, Brain, and Behavior
https://www.readbyqxmd.com/read/29227523/childhood-ingestions-of-environmental-toxins-what-are-the-risks
#13
Marissa Hauptman, Alan D Woolf
Infants and children are at higher risk than adolescents and adults for exposure to environmental toxins via ingestion for a number of reasons: their smaller size (and proportionately larger dose of ingested toxins), their closer proximity to the ground, dirt, and indoor dust, their boundless curiosity and oral exploratory behaviors, pica habits that may persist into school-age for children with autism or other developmental delays, their proportionately larger daily water and milk intake, and food preferences that differ markedly from adolescents and adults...
December 1, 2017: Pediatric Annals
https://www.readbyqxmd.com/read/29226604/an-international-qualitative-study-of-functioning-in-autism-spectrum-disorder-using-the-world-health-organization-international-classification-of-functioning-disability-and-health-framework
#14
Soheil Mahdi, Marisa Viljoen, Tamara Yee, Melissa Selb, Nidhi Singhal, Omar Almodayfer, Mats Granlund, Petrus J de Vries, Lonnie Zwaigenbaum, Sven Bölte
This is the third in a series of four empirical studies designed to develop International Classification of Functioning, Disability and Health (ICF) Core Sets for Autism Spectrum Disorder (ASD). The present study aimed to describe functioning in ASD (as operationalized by the ICF) derived from the perspectives of diagnosed individuals, family members, and professionals. A qualitative study using focus groups and semi-structured interviews were conducted with 19 stakeholder groups (N = 90) from Canada, India, Saudi Arabia, South Africa, and Sweden...
December 11, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/29222612/how-do-parents-manage-irritability-challenging-behaviour-non-compliance-and-anxiety-in-children-with-autism-spectrum-disorders-a-meta-synthesis
#15
Elizabeth O'Nions, Francesca Happé, Kris Evers, Hannah Boonen, Ilse Noens
Although there is increasing research interest in the parenting of children with ASD, at present, little is known about everyday strategies used to manage problem behaviour. We conducted a meta-synthesis to explore what strategies parents use to manage irritability, non-compliance, challenging behaviour and anxiety in their children with ASD. Approaches included: (1) accommodating the child; (2) modifying the environment; (3) providing structure, routine and occupation; (4) supervision and monitoring; (5) managing non-compliance with everyday tasks; (6) responding to problem behaviour; (7) managing distress; (8) maintaining safety and (9) analysing and planning...
December 8, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29214129/using-multiple-exemplar-training-to-teach-empathy-skills-to-children-with-autism
#16
Maithri Sivaraman
The purpose of the study was to use multiple exemplar training to teach empathetic responding to two children with autism. Three emotions-happiness, frustration and sadness/pain-were chosen for this purpose. Treatment consisted of verbal prompting and reinforcement of empathetic responses. Four experimenter-defined categories with discriminative stimuli were used for each emotion. The multiple exemplar component of the model consisted of teaching responses in the presence of several discriminative stimuli drawn from the predefined categories for each emotion delivered by two persons across two environments...
December 2017: Behavior Analysis in Practice
https://www.readbyqxmd.com/read/29214128/a-clinic-based-assessment-for-evaluating-job-related-social-skills-in-adolescents-and-adults-with-autism
#17
Dorothea C Lerman, Bridgette White, Carolyn Grob, Courtney Laudont
Many individuals with autism spectrum disorder (ASD) have difficulties obtaining and maintaining employment, yet little research has evaluated methods for assessing and improving critical vocational skills. In this study, we evaluated an assessment of job-related social skills for individuals with ASD by arranging conditions that simulated on-the-job experiences in a clinic setting. The experimenter contrived situations to assess a variety of social skills, including asking for help, asking for more materials, and responding to corrective feedback...
December 2017: Behavior Analysis in Practice
https://www.readbyqxmd.com/read/29196072/social-involvement-issues-in-patients-with-becker-muscular-dystrophy-a-questionnaire-survey-of-subjects-from-a-patient-registry
#18
Madoka Mori-Yoshimura, Yukio Mizuno, Sumiko Yoshida, Narihiro Minami, Naohiro Yonemoto, Fumi Takeuchi, Ichizo Nishino, Miho Murata, Shin'ichi Takeda, Yuji Takahashi, En Kimura
BACKGROUND: Little is known about the relationship between Becker Muscular Dystrophy (BMD) and developmental problems, school life, employment, and mental problems. We aimed to clarify whether BMD is a risk factor for developmental disorders, problematic behavior, psychiatric diseases, and other social difficulties in school life and employment. METHODS: Adults with genetically or immunohistochemically confirmed BMD from the Registry of Muscular Dystrophy in Japan (REMUDY) were asked to complete a questionnaire regarding patient history, school life, employment, and mental problems...
November 29, 2017: Brain & Development
https://www.readbyqxmd.com/read/29182033/influence-of-physical-activity-on-the-health-related-quality-of-life-of-young-adults-with-and-without-autism-spectrum-disorder
#19
Jessica Hamm, Joonkoo Yun
BACKGROUND: Health-related quality of life constructs has been used to understand the multiple dimensions (i.e., physical health, psychological, environment and social relationships) that affect a person's health status. In order to improve health-related quality of life for young adults, it is important to understand the factors that influence each dimension. The purpose of this paper was to examine the influence of the presence of autism spectrum disorder and physical activity on the multiple domains of health-related quality of life for young adults...
November 28, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29180054/-a-therapeutic-education-program-for-parents-of-children-with-asd-preliminary-results-about-the-effectiveness-of-the-etap-program
#20
C Derguy, M Poumeyreau, S Pingault, K M'bailara
Autism Spectrum Disorders (ASD) are characterized by particularities of cognitive and socio-adaptive functioning. Daily, they require specific interventions for the disabled person as well as support for parents who often report deterioration in their physical and mental health. To this end, the latest Autism Plan 2013-2017 highlights the need "to help families to be present and active alongside their loved ones, to avoid situations of exhaustion and stress and to enable them to play their role fully in the long term"...
November 24, 2017: L'Encéphale
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