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https://www.readbyqxmd.com/read/29452437/successful-treatment-of-giant-esophageal-diverticulum-by-per-oral-endoscopic-myotomy
#1
Chuncheng Wu, Qiongying Zhang, Wei Liu, Bing Hu
No abstract text is available yet for this article.
February 16, 2018: Endoscopy
https://www.readbyqxmd.com/read/29452429/less-invasive-than-minimally-invasive-peroral-endoscopic-myotomy-with-a-slim-scope-in-the-treatment-of-esophageal-achalasia
#2
Antonio Carlos Coelho Conrado, Joao Guilherme Guerra, Claudio Lyoiti Hashimoto, Marcelo Averbach, Miguel Arcanjo Dos Santos, Peter Vassilev Draganov
No abstract text is available yet for this article.
February 16, 2018: Endoscopy
https://www.readbyqxmd.com/read/29452214/pgrn-promotes-lymphangiogenesis-through-vegf-c-and-is-an-independent-risk-factor-in-human-esophageal-cancers
#3
Guanhua Li, Taotao Dong, Dong Yang, Aiqin Gao, Judong Luo, Hongyan Yang, Linlin Wang
Lymph node metastasis is one of the most important predictor of the prognosis for esophageal cancer (EC) patients. Yet, the mechanism underlying the lymph node metastasis is largely unknown. Progranulin (PGRN) is shown to be highly expressed in various types of cancers and could promote the angiogenesis and epithelial mesenchymal transition (EMT) of cancer cells in previous studies. However, the expression status of PGRN and its effects on the lymphangiogenesis in EC is largely unclear. In this study, we show for the first time that PGRN is expressed in EC tissue samples and cell lines and could promote the expression of VEGF-C in vitro, a well-known lymphangiogenesis inducer, through the putative signaling transducers p-ERK and p-AKT...
February 13, 2018: Human Pathology
https://www.readbyqxmd.com/read/29451522/-management-of-benign-esophageal-strictures-a-literature-review
#4
Leonardo Frazzoni, Marina La Marca, Amedeo Montale, Lorenzo Fuccio
The management of benign esophageal strictures is challenging. The first strategy includes endoscopic dilation using bougies or balloons. Although the immediate success rate of these is up to 90%, about 30-40% of patients experience recurrent dysphagia within the first year of follow-up. The management of refractory stenosis involves repeated sessions of endoscopic dilation. In order to obtain long-lasting functional results, alternative treatments have been developed, such as the use of self-expanding stents, particularly indicated in subgroups of patients with post-surgical stenosis or post-radiation therapy...
January 2018: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/29451184/the-long-term-outcomes-of-cirrhotic-patients-with-pleural-effusion
#5
Tsung-Hsing Hung, Chih-Wei Tseng, Chih-Chun Tsai, Chen-Chi Tsai, Kuo-Chih Tseng, Yu-Hsi Hsieh
Background/Aim: A pleural effusion is an abnormal collection of fluid in the pleural space and may cause related morbidity or mortality in cirrhotic patients. Currently, there are insufficient data to support the long-term prognosis for cirrhotic patients with pleural effusion. In this study, we investigated the short- and long-term effects of pleural effusion on mortality in cirrhotic patients and evaluated the benefit of liver transplantation in these patients. Patients and Methods: The National Health Insurance Database, derived from the Taiwan National Health Insurance Program, was used to identify 3,487 cirrhotic patients with pleural effusion requiring drainage between January 1, 2007 and December 31, 2010...
January 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/29451181/the-use-of-nonselective-beta-blockers-is-a-risk-factor-for-portal-vein-thrombosis-in-cirrhotic-patients
#6
Rosa Zampino, Rita Lebano, Nicola Coppola, Margherita Macera, Anna Grandone, Luca Rinaldi, Ilario De Sio, Antonella Tufano, Gianfranca Stornaiuolo, Luigi E Adinolfi, Emanuele Durante-Mangoni, Gaeta G Battista, Alferio Niglio
Background/Aim: A reduction in portal vein inflow velocity seems to predispose to the emergence of portal vein thrombosis (PVT). Nonselective β-blockers (NSBBs), used to prevent variceal bleeding, may increase the development of PVT by reducing portal vein inflow velocity. In this retrospective case-control study, we evaluated the risk factors and clinical features of a first event of PVT in 130 cirrhotics, 19 (15%) with (PVT group) and 111 (85%) without PVT (non-PVT group). Patients and Methods: Patient evaluation and NNBB treatment were carried out according to the AASLD guidelines...
January 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/29451037/esophageal-hiatal-hernia-risk-diagnosis-and-management
#7
Hai-Xiang Yu, Chun-Shan Han, Jin-Ru Xue, Zhi-Feng Han, Hua Xin
Esophageal hiatal hernia involves abnormal abdominal entry into thoracic cavity. It is classified based on orientation between esophageal junction and diaphragm. Sliding hiatal hernia (Type-I) comprises the most frequent category, emanating from right crus of diaphragm. Type-II esophageal hernia engages both left and right muscular crura. Type-III and IV additionally include the left crus. Age and increased body mass index are key risk factors, and congenital skeletal aberrations trigger pathogenesis through intestinal malrotations...
February 16, 2018: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29450752/racial-and-socioeconomic-differences-in-the-use-of-high-volume-commission-on-cancer-accredited-hospitals-for-cancer-surgery-in-the-united-states
#8
Nabil Wasif, David Etzioni, Elizabeth B Habermann, Amit Mathur, Barbara A Pockaj, Richard J Gray, Yu-Hui Chang
BACKGROUND: Although major cancer surgery at a high-volume hospital is associated with lower postoperative mortality, the use of such hospitals may not be equally distributed. OBJECTIVE: Our aim was to study socioeconomic and racial differences in cancer surgery at Commission on Cancer (CoC)-accredited high-volume hospitals. METHODS: The National Cancer Database (NCDB) was used to identify patients undergoing surgery for colon, esophageal, liver, and pancreatic cancer from 2003 to 2012...
February 15, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29449355/red-alert-infrared-thermography-for-esophageal-monitoring
#9
EDITORIAL
Ryan T Borne, Duy T Nguyen
No abstract text is available yet for this article.
February 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29449354/high-resolution-infrared-thermography-of-esophageal-temperature-during-radiofrequency-ablation-of-atrial-fibrillation
#10
Matthew G Daly, Iain Melton, Graham Roper, Gary Lim, Ian G Crozier
BACKGROUND: Catheter ablation for atrial fibrillation has potential to cause esophageal thermal injury. Esophageal temperature monitoring during ablation is commonly used; however, it has not eliminated thermal injuries, possibly because conventional sensors have poor spatial sampling and response characteristics. To enhance understanding of temperature dynamics that may underlie esophageal injury, we tested a high-resolution, intrabody, infrared thermography catheter to continuously image esophageal temperatures during ablation...
February 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29448289/lessons-from-pathological-analysis-of-recurrent-early-esophageal-squamous-cell-neoplasia-after-complete-endoscopic-radiofrequency-ablation
#11
Wen-Lun Wang, I-Wei Chang, Chien-Chuan Chen, Chi-Yang Chang, Cheng-Hao Tseng, Chi-Ming Tai, Jaw-Town Lin, Hsiu-Po Wang, Ching-Tai Lee
BACKGROUND: Endoscopic radiofrequency ablation (RFA) is a treatment option for early esophageal squamous cell neoplasia (ESCN); however, long-term follow-up studies are lacking. The risks of local recurrence and "buried cancer" are also uncertain. METHODS: Patients with flat-type ESCN who were treated with balloon-type ± focal-type RFA were consecutively enrolled. Follow-up endoscopy was performed at 1, 3, and 6 months, and then every 6 months thereafter...
February 15, 2018: Endoscopy
https://www.readbyqxmd.com/read/29448218/polymer-adhesion-predictions-for-oral-dosage-forms-to-enhance-drug-administration-safety-part-1-in-vitro-approach-using-particle-interaction-methods
#12
Nélio Drumond, Sven Stegemann
Solid oral dosage forms (SODF) are drug vehicles commonly prescribed by physicists in primary and secondary cares, as they are the most convenient for the patient and facilitate therapy management. Concerns regarding unintended adhesion of SODF during oro-esophageal transit remain, especially in multimorbid patients, bedridden patients and patients suffering from dysphagia. Hence, this factor should be considered during the development of SODF, and more attention should be given on the design of appropriate surface conditions considering patients with swallowing problems...
February 9, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29447899/geographic-health-disparities-in-the-los-angeles-pediatric-esophageal-foreign-body-population
#13
Kevin Hur, Varun Angajala, Dennis Maceri, Christian Hochstim
OBJECTIVE: To assess geographical sociodemographic differences in the pediatric esophageal foreign body population of Los Angeles. METHODS: We retrospectively reviewed the medical records of 128 consecutive pediatric patients at Children's Hospital Los Angeles (CHLA) from 2014 to 2017 with a diagnosis of a retained foreign body in the esophagus removed by rigid or flexible esophagoscopy. Sociodemographic information including zip code of residence was extracted and analyzed with Chi-square, Fisher's exact test, and multivariable logistic regression...
March 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29447795/modified-approach-for-pediatric-external-cricopharyngeal-myotomy
#14
Suresh Mohan, Sarah N Bowe, Lara M Hirner, Claire Zar-Kessler, Christopher J Hartnick
Pediatric cricopharyngeal achalasia is an uncommon but important cause of oropharyngeal dysphagia. Failure of upper esophageal sphincter relaxation is the currently understood pathophysiology. Therapies include balloon dilation, botulinum toxin injection, and endoscopic or open cricopharyngeal myotomy (CPM). Open CPM is usually performed at the posterior midline of the cricopharyngeus and can be a risky procedure given concern for esophageal perforation and damage to the recurrent laryngeal nerve. Here, we present a novel modified technique for open CPM using a superficial anterolateral transection approach in the case of a young male with refractory cricopharyngeal achalasia...
February 2018: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/29447301/esophageal-squamous-cell-carcinoma-with-low-mitochondrial-copy-number-has-mesenchymal-and-stem-like-characteristics-and-contributes-to-poor-prognosis
#15
Yasunori Masuike, Koji Tanaka, Tomoki Makino, Makoto Yamasaki, Yasuhiro Miyazaki, Tsuyoshi Takahashi, Yukinori Kurokawa, Kiyokazu Nakajima, Masaki Mori, Yuichiro Doki
Alterations in mitochondrial DNA (mtDNA) copy numbers in various human cancers have been studied, but any such changes in esophageal squamous cell carcinoma (ESCC) are not established. In the present study, we investigated the correlation of mtDNA copy number with clinicopathologic features, prognosis, and malignant potential of ESCC. MtDNA copy numbers of resected specimens from 80 patients treated with radical esophagectomy were measured by quantitative real-time PCR analyses. Human ESCC cells, TE8 and TE11, were cultured, and depletion of mtDNA content was induced by knockdown of mitochondrial transcription factor A expression or treatment with ethidium bromide...
2018: PloS One
https://www.readbyqxmd.com/read/29446327/changes-in-life-expectancy-from-2006-to-2015-in-suzhou-east-china-contributions-of-age-and-cause-specific-mortality
#16
Chunyan Huang, Xinyuan Zhao, Yan Lu, Linchi Wang, Yihe Hu, Jun Zhang, Qiaoliang Huang, Gang Chen
This study was designed to estimate the contribution of age- and disease-specific mortality, particularly that attributable to chronic noncommunicable diseases and at-birth life expectancy (LE) in Suzhou, East China, between 2006 and 2015. In total, data on 427 290 deaths were analyzed. From 2006 to 2015, the at-birth LE increased from 78.92 years to 82.87 years in Suzhou. A decrease in all-cause age-specific death rates contributed to an increase of 1.98 years. The decreased death rates attributable to noncommunicable diseases including cerebrovascular diseases, cancer, heart disease, and respiratory diseases resulted in an increased LE of 1...
January 2018: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/29445485/esophageal-atresia-and-beckwith-wiedemann-syndrome-in-one-of-the-naturally-conceived-discordant-newborn-twins-first-report
#17
Gregorio Serra, Vincenzo Antona, Mandy Schierz, Davide Vecchio, Ettore Piro, Giovanni Corsello
Recent studies report a high incidence of monozygotic twinning in Beckwith-Wiedemann syndrome. A phenotypical discordance in monozygotic twins is rare. Twinning and Beckwith-Wiedemann syndrome show higher incidence in children born after assisted reproductive techniques. We report on the first observation of esophageal atresia and Beckwith-Wiedemann syndrome in one of the naturally conceived discordant monozygotic twins.
February 2018: Clinical Case Reports
https://www.readbyqxmd.com/read/29444657/understanding-the-rapid-increase-in-life-expectancy-in-shanghai-china-a-population-based-retrospective-analysis
#18
Hanyi Chen, Lipeng Hao, Chen Yang, Bei Yan, Qiao Sun, Lianghong Sun, Hua Chen, Yichen Chen
BACKGROUND: Life expectancy at birth (LE) is a comprehensive measure that accounts for age-specific death rates in a population. Shanghai has ranked first in LE in China mainland for decades. Understanding the reasons behind its sustained gain in LE provides a good reflection of many other cities in China. The aim of this study is intended to explore temporal trend in age- and cause-specific gains in LE in Shanghai and the probable reasons lay behind. METHODS: Joinpoint regression was applied to evaluate temporal trend in LE and the long time span was then divided accordingly...
February 14, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29444644/use-of-esophageal-balloon-pressure-volume-curve-analysis-to-determine-esophageal-wall-elastance-and-calibrate-raw-esophageal-pressure-a-bench-experiment-and-clinical-study
#19
Xiu-Mei Sun, Guang-Qiang Chen, Hua-Wei Huang, Xuan He, Yan-Lin Yang, Zhong-Hua Shi, Ming Xu, Jian-Xin Zhou
BACKGROUND: Accurate measurement of esophageal pressure (Pes) depends on proper filling of the balloon. Esophageal wall elastance (Ees) may also influence the measurement. We examined the estimation of balloon-surrounding elastance in a bench model and investigated a simplified calibrating procedure of Pes in a balloon with relatively small volume. METHODS: The Cooper balloon catheter (geometric volume of 2.8 ml) was used in the present study. The balloon was progressively inflated in different gas-tight glass chambers with different inner volumes...
February 14, 2018: BMC Anesthesiology
https://www.readbyqxmd.com/read/29444329/gastroesophageal-reflux-symptoms-are-not-sufficient-to-guide-esophageal-function-testing-in-lung-transplant-candidates
#20
S Posner, J Zheng, R K Wood, R A Shimpi, M G Hartwig, S-C Chow, D A Leiman
Gastroesophageal reflux disease and esophageal dysmotility are prevalent in patients with advanced lung disease and are associated with graft dysfunction following lung transplantation. As a result, many transplant centers perform esophageal function testing as part of the wait-listing process but guidelines for testing in this population are lacking. The aim of this study is to describe whether symptoms of gastroesophageal reflux correlate with abnormal results on pH-metry and high-resolution manometry and can be used to identify those who require testing...
February 9, 2018: Diseases of the Esophagus: Official Journal of the International Society for Diseases of the Esophagus
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