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https://www.readbyqxmd.com/read/29454100/patient-centered-outcomes-after-laparoscopic-paraesophageal-hernia-repair
#1
Tyler Hall, Natalie Warnes, Kristine Kuchta, Stephanie Novak, Herbert Hedberg, John G Linn, Stephen Haggerty, Woody Denham, Raymond J Joehl, Michael Ujiki
BACKGROUND: The aim of this study is to investigate patient centered quality of life (QOL) outcomes in patients undergoing laparoscopic paraesophageal hernia repair (LPEHR). STUDY DESIGN: We prospectively followed patients who underwent laparoscopic paraesophageal hernia repair between 2009 - 2016. QOL outcomes were measured using Short Form-36 (SF-36), GERD-HRQL, Reflux Symptom Index, and Dysphagia score surveys administered pre-operatively and at 3 weeks, 6 months, 1 year, and 2 years post- operatively...
February 14, 2018: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29436209/focus-on-gastroesophageal-reflux-ger-and-laryngopharyngeal-reflux-lpr-new-pragmatic-insights-in-clinical-practice
#2
M Gelardi, G Ciprandi
Gastroesophageal reflux (GER) is a common disease usually limited to the oesophagus. Laryngopharyngeal reflux (LPR) is an inflammatory reaction of the mucosa of pharynx, larynx, and other associated upper respiratory organs, caused by a reflux of stomach contents outside the oesophagus. LPR is considered to be a relatively new clinical entity with a vast number of clinical manifestations which are treated sometimes empirically and without a correct diagnosis. However, there is disagreement between specialists about its definition and management: gastroenterologists consider LPR to be a substantially rare manifestation of gastroesophageal reflux disease (GERD), whereas otolaryngologists believe that LPR is an independent, but common in their practice, disorder...
January 2018: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/29435755/surgical-management-of-gastroesophageal-reflux-disease-in-patients-with-systemic-sclerosis
#3
Jingliang Yan, Andrew T Strong, Gautam Sharma, Scott Gabbard, Prashanti Thota, John Rodriguez, Matthew Kroh
BACKGROUND: Systemic sclerosis (scleroderma) is frequently associated with both gastroesophageal reflux disease (GERD) and simultaneous esophageal dysmotility. Anti-reflux procedures in this patient population must account for the existing physiology of each patient and likely disease progression. We aim to compare perioperative and intermediate outcomes of fundoplication versus gastric bypass for the treatment of GERD. METHODS: After IRB approval, patients with systemic sclerosis undergoing fundoplication or gastric bypass for the treatment of GERD from 2004 to 2016 were identified...
February 12, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29421814/herbal-preparation-stw%C3%A2-5-for-functional-gastrointestinal-disorders-clinical-experience-in-everyday-practice
#4
Tatiana L Lapina, Alexander S Trukhmanov
BACKGROUND: The most common functional gastrointestinal disorders (FGID) are functional dyspepsia (FD) and irritable bowel syndrome (IBS), with a prevalence in the general population of 15-20% (FD) and 10% (IBS), respectively. The complexity of pathophysiologic mechanisms and limitations in therapeutic options make the management of FD and IBS patients a challenge in routine clinical practice. SUMMARY: Syndromes classified as FGID frequently overlap, and coexist with gastroesophageal reflux disease (GERD)...
February 8, 2018: Digestive Diseases
https://www.readbyqxmd.com/read/29416208/gigantic-thrombus-of-the-left-atrium-in-mitral-stenosis
#5
Enisa Hodzic, Nermir Granov
Introduction: Excess dilatation of the left atrium >65 mm is known in the literature as gigantic atrium. This dilation is most commonly encountered in the mitral insufficiency of rheumatic etiology, but also in severe prolapses of the mitral valve, permanent atrial fibrillation, and at the left right shunt with cardiac insufficiency. Case report: In this paper is presented a case study of echocardiographically verified giant thrombus in left atrium in a 50 years old female patient aged 50 hospitalized because of tiredness, choking, heartburn and urinary tract symptoms...
December 2017: Medical Archives
https://www.readbyqxmd.com/read/29403613/profile-of-peptic-ulcer-disease-and-its-risk-factors-in-arar-northern-saudi-arabia
#6
Afaf Shuaib Badi Albaqawi, Nagah Mohamed Abo El-Fetoh, Reem Faleh Abdullah Alanazi, Najah Salah Farhan Alanazi, Sara Emad Alrayya, Arwa Nughaymish Mulfi Alanazi, Shoug Zeid Trad Alenezi, Rehab Abdallah Alrkowi Alanazi, Anfal Muaddi Alshalan, Omar Tabaan Alenezi, Wafaa Mohamed Bakr Ali
Background: Peptic ulcer disease is a multifactorial health problem, and its prevalence and risk factors have changed considerably within the past century. Objective: To determine the prevalence of peptic ulcer among the population of Arar city and to identify risk factors for peptic ulcer and to estimate their relative impact on ulcer incidence. Methods: A cross-sectional study was carried out on the population of Arar city, Northern Saudi Arabia from November 01, 2016 to April 30, 2017...
November 2017: Electronic Physician
https://www.readbyqxmd.com/read/29396034/epidemiology-clinical-characteristics-and-associations-for-symptom-based-rome-iv-functional-dyspepsia-in-adults-in-the-usa-canada-and-the-uk-a-cross-sectional-population-based-study
#7
Imran Aziz, Olafur S Palsson, Hans Törnblom, Ami D Sperber, William E Whitehead, Magnus Simrén
BACKGROUND: The population prevalence, clinical characteristics, and associations for Rome IV functional dyspepsia are not known. Following the publication of the Rome IV criteria for functional gastrointestinal disorders, we aimed to assess the prevalence, characteristics, and associations for symptom-based Rome IV functional dyspepsia in adults across the USA, Canada, and the UK. METHODS: We sent an internet-based cross-sectional health survey to adults in the general population of three English-speaking countries: the USA, Canada, and the UK...
January 29, 2018: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29394582/-a-case-report-of-maintaining-continuous-ambulatory-peritoneal-dialysis-after-total-gastrectomy-for-perforated-gastric-cancer-with-esd
#8
Masanori Yamada, Koji Nakai, Takeshi Hijikawa, Taisaku Hachimine, Hiroya Masaki, Kazuhiko Yoshioka, Kentaro Inoue
A 73-year-old man, receiving maintenance continuous ambulatory peritoneal dialysis(CAPD)was admitted to our hospital for chief complaining of heartburn. Gastrointestinal endoscopy disclosed 0- II a on the greater curvature of the upper gastric body. On further examination, the clinical diagnosis was defined as gastric cancer and c-stage I A(cT1aN0M0). The patient was recovered with conservative treatment from the perforated peritonitis after undergoing endoscopic submucosal dissection(ESD). Pathology revealed pT1b, INF b, UL(-), ly2, v0, pHM0, pVM0, for which he underwent total gastrectomy after changed to temporary hemodialysis(HD)...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29384872/the-psychological-results-of-438-patients-with-persisting-gerd-symptoms-by-symptom-checklist-90-revised-scl-90-r-questionnaire
#9
Ping Li, Fei Wang, Guo-Zhong Ji, Lin Miao, Sihong You, Xia Chen
Persisting gastroesophageal reflux disease (GERD) symptoms affect mental state and social activities and mental disorders likewise play a crucial role on GERD symptoms. The aim of this study was to analyze the data of Symptom Checklist by 90-Revised (SCL-90-R) questionnaire in patients with persisting GERD symptom and to explore the impact of psychological factors on them.The patients accepted SCL-90-R questionnaire survey, following endoscopy, high-resolution manometry (HRM) and ambulatory impedance-pH monitoring...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29372566/symptom-associated-probability-does-not-reliably-distinguish-functional-heartburn-from-reflux-hypersensitivity
#10
Y Choksi, J C Slaughter, R Sharda, T Higginbotham, P Lal, M F Vaezi
BACKGROUND: Symptom association probability (SAP) is thought to distinguish reflux hypersensitivity from functional disorders. A diagnosis of hypersensitive oesophagus (SAP-positive) indicates that gastro-oesophageal reflux disease (GERD) is the cause of continued symptoms. AIM: To conduct an analysis of pH and symptom criteria that lead to a diagnosis of SAP-positivity METHODS: We calculated SAP for 205 patients with GERD symptoms refractory to proton pump inhibitor (PPI) therapy who underwent endoscopy with wireless pH monitoring from 2007 to 2014...
January 26, 2018: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29372475/acid-secretion-and-its-relationship-to-esophageal-reflux-symptom-in-patients-with-subtotal-gastrectomy
#11
Hyun Jin Oh, Myung-Gyu Choi, Jae Myung Park, Kyo Young Song, Han Mo Yoo
BACKGROUND: Esophageal reflux symptom has been reported as common in patients with subtotal gastrectomy. Management of postoperative esophageal reflux symptom is not satisfactory. The aim of this study is to investigate prevalence of esophageal reflux symptom after subtotal gastrectomy and assess factors affecting esophageal reflux symptom in subtotal gastrectomy patients. METHODS: We prospectively enrolled 100 consecutive patients with subtotal gastrectomy who were regularly followed up by endoscopic examination...
January 25, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29368532/image-enhanced-endoscopy-is-specific-for-the-diagnosis-of-non-erosive-gastroesophageal-reflux-disease
#12
Neil D Parikh, Artur V Viana, Saloni Shah, Loren Laine
OBJECTIVES: We assessed the performance characteristics of image-enhanced endoscopy with i-Scan or narrow band imaging (NBI) in patients with non-erosive gastroesophageal reflux disease (GERD) compared to controls without heartburn. MATERIAL AND METHODS: Image-enhanced endoscopic findings of vascularity at the squamocolumnar junction, distal esophageal micro-erosions, and non-round pit pattern at the squamocolumnar junction were assessed in cases (heartburn not responsive to PPIs, positive results on validated GERD questionnaire, no esophageal erosions, esophageal biopsies with histologic evidence of GERD (basal cell hyperplasia, elongation of papillae and dilation of intercellular spaces all required)) and in controls (no GERD symptoms or esophageal erosions)...
January 25, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29354987/-clinical-trial-of-gastroesophageal-reflux-disease-with-the-disharmony-between-liver-and-stomach-syndrome-treated-with-acupuncture-regulating-qi-based-on-the-compatibility-of-the-five-meridians
#13
Shimin Pan, Jinxiang Li, Xi Zhang, Ying Li, Jie Yan, Wei Zhang, Sha Hu
OBJECTIVE: To observe the clinical effects of the acupuncture regulating qi based on the compatibility of the five meridians and common western medication for gastroesophageal reflux disease with the disharmony between liver and stomach. METHODS: Sixty patients were divided into two groups according to non-erosive reflux disease (NERD) and reflux esophagitis (RE). Those in the two groups were randomly assigned into an observation group and a control group. There were 57 cases included (28 in the observation group with 2 dropping, 29 in the control group with 1 dropping)...
December 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29352757/refractory-heartburn-a-challenging-problem-in-clinical-practice
#14
REVIEW
Gerson Domingues, Joaquim Prado P Moraes-Filho, Ronnie Fass
Gastroesophageal reflux disease (GERD) is a condition which develops when the reflux of stomach contents causes troublesome symptoms and/or complications. Heartburn and regurgitation are the typical symptoms of GERD. The treatment of GERD encompasses lifestyle modifications, pharmacological, endoscopic, and surgical therapy. The majority of the patients respond to 4-8 weeks of proton-pump inhibitors therapy, but 20-42% will demonstrate partial or complete lack of response to treatment. While these patients have been considered as having refractory heartburn, a subset of them does not have GERD or have not been adequately treated...
January 20, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29339948/update-on-functional-heartburn
#15
Takahisa Yamasaki, Jessica O'Neil, Ronnie Fass
The definition of functional heartburn has been refined over the years. It is currently described, based upon Rome IV criteria, as typical heartburn symptoms in the presence of normal upper endoscopy findings (including normal biopsies), normal esophageal pH testing, and a negative association between symptoms and reflux events. Functional heartburn is very common, affecting women more than men, and with reflux hypersensitivity makes up the majority of heartburn patients who fail twice-daily proton pump inhibitor therapy...
December 2017: Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29339946/functional-heartburn
#16
(no author information available yet)
No abstract text is available yet for this article.
December 2017: Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29333061/critical-appraisal-of-rome-iv-criteria-hypersensitive-esophagus-does-belong-to-gastroesophageal-reflux-disease-spectrum
#17
REVIEW
Leonardo Frazzoni, Marzio Frazzoni, Nicola de Bortoli, Salvatore Tolone, Irene Martinucci, Lorenzo Fuccio, Vincenzo Savarino, Edoardo Savarino
The Rome IV Committee introduced a major change in the classification of functional gastrointestinal disorders, proposing a more restrictive definition of gastroesophageal reflux disease (GERD). It was suggested that hypersensitive esophagus (HE) may sit more firmly within the functional realm. It was suggested that GERD diagnosis should be based upon abnormal acid exposure time (AET) only, implying no advantage of impedance-pH over pH monitoring. Symptom association probability (SAP), symptom index (SI) and heartburn relief with proton pump inhibitor (PPI) therapy were regarded as unreliable, whereas a lack of response to PPI was considered as evidence of functional heartburn...
January 2018: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/29330729/revenge-of-the-nerds-cadherin-fragments-differentiate-functional-heartburn-from-non-erosive-reflux-disease
#18
EDITORIAL
Carlo Calabrese, Marco Salice
No abstract text is available yet for this article.
January 12, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29311180/the-day-i-died
#19
Julie M Stausmire, Mitchell G Greenbaum, Marie Morelli-Greenbaum
When I began experiencing chest pain that was different from my usual heartburn symptoms, I denied I could possibly be having a heart attack, but chewed 4 baby aspirin just in case. Despite years of community education about the need to call 911 and seek immediate emergency care when experiencing signs and symptoms of a heart attack, more than 350,000 individuals experienced an out-of-hospital cardiac arrest in 2016. Of those, only 12% survived. Bystander recognition of cardiac arrest and prompt intervention with cardiopulmonary resuscitation (CPR) and rapid defibrillation is essential for out-of-hospital survival...
January 2018: Annals of Family Medicine
https://www.readbyqxmd.com/read/29303805/randomized-trial-of-division-versus-nondivision-of-short-gastric-vessels-during-nissen-fundoplication-20-year-outcomes
#20
Stephen P Kinsey-Trotman, Peter G Devitt, Tim Bright, Sarah K Thompson, Glyn G Jamieson, David I Watson
OBJECTIVE: To evaluate late outcomes from a randomized trial of division versus no division of short gastric vessels during laparoscopic Nissen fundoplication at up to 20 years follow-up. BACKGROUND: Nissen fundoplication is an established procedure for the treatment of gastroesophageal reflux disease. Controversy about whether side effects such as dysphagia could be reduced by division of the short gastric vessels led to the establishment of a randomized trial in 1994...
January 4, 2018: Annals of Surgery
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