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Spinal cord injury rehabilitation

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https://www.readbyqxmd.com/read/28101559/cannabis-use-in-persons-with-traumatic-spinal-cord-injury-in-denmark
#1
Sven R Andresen, Fin Biering-Sørensen, Ellen Merete Hagen, Jørgen F Nielsen, Flemming W Bach, Nanna B Finnerup
OBJECTIVE: To evaluate recreational and medical cannabis use in individuals with traumatic spinal cord injury, including reasons and predictors for use, perceived benefits and negative consequences. DESIGN: Cross-sectional survey in Denmark. METHODS: A 35-item questionnaire was sent to 1,101 patients with spinal cord injury who had been in contact with a rehabilitation centre between 1990 and 2012. RESULTS: A total of 537 participants completed the questionnaire...
January 18, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28096400/defining-recovery-neurobiology-of-injured-spinal-cord-by-synthetic-matrix-assisted-hmsc-implantation
#2
Alexander E Ropper, Devang K Thakor, InBo Han, Dou Yu, Xiang Zeng, Jamie E Anderson, Zaid Aljuboori, Soo-Woo Kim, Hongjun Wang, Richard L Sidman, Ross D Zafonte, Yang D Teng
Mesenchymal stromal stem cells (MSCs) isolated from adult tissues offer tangible potential for regenerative medicine, given their feasibility for autologous transplantation. MSC research shows encouraging results in experimental stroke, amyotrophic lateral sclerosis, and neurotrauma models. However, further translational progress has been hampered by poor MSC graft survival, jeopardizing cellular and molecular bases for neural repair in vivo. We have devised an adult human bone marrow MSC (hMSC) delivery formula by investigating molecular events involving hMSCs incorporated in a uniquely designed poly(lactic-co-glycolic) acid scaffold, a clinically safe polymer, following inflammatory exposures in a dorsal root ganglion organotypic coculture system...
January 17, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28094580/is-walking-symmetry-important-for-ambulatory-patients-with-spinal-cord-injury
#3
Makamas Kumprou, Pipatana Amatachaya, Thanat Sooknuan, Thiwabhorn Thaweewannakij, Sugalya Amatachaya
PURPOSE: To assess and compare the levels of walking symmetry in ambulatory participants with spinal cord injury (SCI) who had different degrees of lesion severity, levels of walking ability, and fall history. In addition, the study explored the relationship between the levels of walking symmetry and variables related to the ability of well-controlled walking of the participants. STUDY DESIGN: Cross-sectional study. METHODS: Sixty-six eligible participants were assessed and interviewed for levels of walking symmetry, walking speed, functional endurance, symmetrical lower limb support ability, balance control, and fall history over the last 6 months...
January 17, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28091431/determinants-of-quality-of-life-among-community-dwelling-persons-with-spinal-cord-injury-a-path-analysis
#4
End Ekechukwu, J O Ikrechero, A O Ezeukwu, A V Egwuonwu, L Umar, U M Badaru
CONTEXT: Recent advancement in technology and medical care has resulted in an increase not only in disability arising from spinal cord injury (SCI) but also its attendant challenges such as poor quality of life (QoL). AIM: To test a theoretical model of predictors of QoL among persons with SCI. SETTINGS AND DESIGN: Study was conducted in the South Eastern Nigeria. A longitudinal study design was employed. MATERIALS AND METHODS: A total of 64 persons with SCI discharged from in-hospital admission participated in this study...
February 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28089563/diagnostic-and-prognostic-relevance-of-magnetic-resonance-imaging-and-electrophysiological-findings-in-acute-spinal-ischemia
#5
Dimitrios Artemis, Marc Wolf, Christian Blahak, Kristina Szabo, Michael G Hennerici, Marc Fatar
OBJECTIVE: Our purpose was to classify the rare entity of spontaneous spinal ischemia with clinical, magnetic resonance-tomographic, and electrophysiological parameters to determine criteria for outcome prediction. METHODS: We analyzed the stroke registry database of the University Hospital Mannheim, Germany, from 2004 to 2010 for patients with a diagnosis of vascular spinal cord ischemia. RESULTS: Ten patients were identified (mean age 65 years [range 50-83], 5 women)...
January 12, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28068293/a-hybrid-bmi-based-exoskeleton-for-paresis-emg-control-for-assisting-arm-movements
#6
Toshihiro Kawase, Takeshi Sakurada, Yasuharu Koike, Kenji Kansaku
OBJECTIVE: Brain-machine interface (BMI) technologies have succeeded in controlling robotic exoskeletons, enabling some paralyzed people to control their own arms and hands. We have developed an exoskeleton asynchronously controlled by EEG signals. In this study, to enable real-time control of the exoskeleton for paresis, we developed a hybrid system with EEG and EMG signals, and the EMG signals were used to estimate its joint angles. APPROACH: Eleven able-bodied subjects and two patients with upper cervical spinal cord injuries (SCIs) performed hand and arm movements, and the angles of the metacarpophalangeal (MP) joint of the index finger, wrist, and elbow were estimated from EMG signals using a formula that we derived to calculate joint angles from EMG signals, based on a musculoskeletal model...
January 9, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28067245/effect-of-hierarchically-aligned-fibrin-hydrogel-in-regeneration-of-spinal-cord-injury-demonstrated-by-tractography-a-pilot-study
#7
Zhenxia Zhang, Shenglian Yao, Sheng Xie, Xiumei Wang, Feiyan Chang, Jie Luo, Jingming Wang, Jun Fu
Some studies have reported that scaffold or cell-based transplantation may improve functional recovery following SCI, but no imaging information regarding regeneration has been provided to date. This study used tractography to show the regenerating process induced by a new biomaterial-aligned fibrin hydrogel (AFG). A total of eight canines subjected to SCI procedures were assigned to the control or the AFG group. AFG was implanted into the SCI lesion immediately after injury in 5 canines. A follow-up was performed at 12 weeks to evaluate the therapeutic effect including the hindlimb functional recovery, anisotropy and continuity of fibers on tractography...
January 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28059878/the-cross-cultural-societal-response-to-sci-health-and-related-systems
#8
Diana Pacheco Barzallo, Mirja H Gross-Hemmi
OBJECTIVE: The Learning Health System for Spinal Cord Injury (LHS-SCI) is an initiative aligned with the World Health Organization's (WHO) Global Disability Action Plan. Based on the outcomes of this initiative, countries will be able to shape their health systems to better respond to the needs of persons with SCI. This paper describes and compares the macroeconomic situation and societal response to SCI across 27 countries from all 6 WHO regions that will participate in the LHS-SCI initiative...
February 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28059877/rehabilitation-services-provision-and-payment
#9
Christoph Gutenbrunner, Melanie Blumenthal, Veronika Geng, Christoph Egen
Persons with spinal cord injury (SCI) experience disability and have significant need for rehabilitation. To deliver appropriate rehabilitation, interventions and programs suitable services must exist. A prerequisite for system improvement is a description of rehabilitation services. The aim of this paper was to develop a rehabilitation service framework for SCI. Additionally, principles and models of payment of rehabilitation services will be discussed. Health-related rehabilitation services should be available along the continuum of care and implemented at all levels of health care...
February 2017: American Journal of Physical Medicine & Rehabilitation
https://www.readbyqxmd.com/read/28054832/a-qualitative-exploration-of-living-with-chronic-neuropathic-pain-after-spinal-cord-injury-an-italian-perspective
#10
Valentina Buscemi, Elizabeth Cassidy, Cherry Kilbride, Frances Ann Reynolds
PURPOSE: The purpose of this study is to understand how people with spinal cord injury (SCI) in Italy experienced and managed chronic neuropathic pain (CNP), and their perspectives of Italian healthcare services. METHOD: Nine people with SCI participated. Two focus groups (three and four individuals) and one semi-structured interview were audio-recorded and transcribed. One "virtual interview" was conducted via e-mail. A qualitative thematic analysis was undertaken...
January 5, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28044436/evaluation-of-a-self-efficacy-enhancement-program-to-prevent-pressure-ulcers-in-patients-with-a-spinal-cord-injury
#11
Jung Yoon Kim, Eunhee Cho
AIM: This study developed a self-efficacy enhancement program and evaluated its effects on the self-care behaviors, self-care knowledge, and self-efficacy regarding pressure ulcer prevention in patients with a spinal cord injury. METHODS: This was a multicenter randomized controlled trial. Six hospitals were invited to recruit patients with a spinal cord injury who were undergoing rehabilitation after receiving acute treatment. These hospitals were randomly allocated into experimental (three hospitals) or control (three hospitals) groups and 47 patients participated (24 in the experimental group and 23 in the control group)...
January 2017: Japan Journal of Nursing Science: JJNS
https://www.readbyqxmd.com/read/28043106/factors-affecting-quality-of-life-among-spinal-cord-injury-patients-in-korea
#12
Jong Soo Lee, Sang Woon Kim, Sang Hyun Jee, Joon Chul Kim, Jong Bo Choi, Sung Yong Cho, Jang Hwan Kim
PURPOSE: Complaints from spinal cord injury (SCI) patients are typically related to physical disability affecting activities of daily life. However, difficulties with voiding and defecation and/or sexual function can also be major concerns. The general population and even physicians are generally unaware of these complaints; therefore, this study focuses on surveying SCI patients regarding challenges that are faced in daily life. METHODS: A questionnaire was administered randomly and anonymously to SCI patients who visited the Korea Spinal Cord Injury Association and several rehabilitation hospitals in the Republic of Korea in 2013...
December 2016: International Neurourology Journal
https://www.readbyqxmd.com/read/28031400/spinal-cord-direct-current-stimulation-differentially-modulates-neuronal-activity-in-the-dorsal-and-ventral-spinal-cord
#13
Weiguo Song, John H Martin
Spinal cord direct current stimulation (sDCS) has the potential for promoting motor function after injury through its modulatory actions on sensory processing, reflex functions, the motor cortex (M1) motor map, and motor output. Here we addressed systems-level mechanisms underlying sDCS neuromodulation of spinal circuits activated by M1 and peripheral forelimb electrical stimulation in anesthetized healthy rats. We determined the effects of cathodal and anodal sDCS (c- and a-sDCS) on local field potentials (LFP) and single-unit activity recorded at 32 sites simultaneously within the 6th cervical segment using a silicon multi-electrode array...
December 28, 2016: Journal of Neurophysiology
https://www.readbyqxmd.com/read/28030515/employment-outcomes-following-spinal-cord-injury-in-taiwan
#14
I-C Huang
It is important to maximize vocational achievement following spinal cord injury. Despite this recognition, unemployment remains a prevalent problem and continues to challenge rehabilitation professionals. This study aimed to examine the employment status and determinants of employability for individuals with spinal cord injury in Taiwan. A cross-sectional survey was conducted. A total of 353 participants aged 18-65 years were recruited from four branches of the Association of People with Spinal Cord Injury...
December 26, 2016: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/28029067/the-relationship-between-the-implementation-and-effectiveness-of-a-nationwide-physical-activity-telephone-counseling-service-for-adults-with-spinal-cord-injury
#15
Jennifer R Tomasone, Kelly P Arbour-Nicitopoulos, Amy E Latimer-Cheung, Kathleen A Martin Ginis
PURPOSE: Get in Motion (GIM) is an evidence-based telephone counseling service that promotes leisure-time physical activity (LTPA) among Canadian adults with spinal cord injury (SCI). The first phase of GIM sustained intentions for, and increased participation in, LTPA; however, it is unclear how GIM led to these outcomes. The purpose of this study was to explore the implementation correlates of change in LTPA intentions and behavior in the second phase of GIM. METHODS: The frequency, duration, and content of counseling sessions were tailored to meet clients' (N = 46; 50...
December 28, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28025254/shaping-the-output-of-lumbar-flexor-motoneurons-by-sacral-neuronal-networks
#16
Meir Cherniak, Lili Anglister, Aharon Lev-Tov
: The ability to improve motor function in spinal cord injury patients by reactivating spinal central pattern generators (CPGs) requires the elucidation of neurons and pathways involved in activation and modulation of spinal networks in accessible experimental models. Previously we reported on adrenoceptor-dependent sacral control of lumbar-flexor motoneuron firing in newborn rats. The current work focuses on clarification of the circuitry and connectivity involved in this unique modulation and its potential use...
December 26, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28007647/rewiring-the-spinal-cord-direct-and-indirect-strategies
#17
REVIEW
Maria Teresa Dell'Anno, Stephen M Strittmatter
Spinal cord injury is currently incurable. Treatment is limited to minimizing secondary complications and maximizing residual function by rehabilitation. Neurologic recovery is prevented by the poor intrinsic regenerative capacity of neurons in the adult central nervous system and by the presence of growth inhibitors in the adult brain and spinal cord. Here we identify three approaches to rewire the spinal cord after injury: axonal regeneration (direct endogenous reconnection), axonal sprouting (indirect endogenous reconnection) and neural stem cell transplantation (indirect exogenous reconnection)...
December 19, 2016: Neuroscience Letters
https://www.readbyqxmd.com/read/28002472/manual-wheelchair-skills-training-for-community-dwelling-veterans-with-spinal-cord-injury-a-randomized-controlled-trial
#18
R Lee Kirby, Doug Mitchell, Sunil Sabharwal, Mark McCranie, Audrey L Nelson
OBJECTIVES: To test the hypotheses that community-dwelling veterans with spinal cord injury (SCI) who receive the Wheelchair Skills Training Program (WSTP) in their own environments significantly improve their manual wheelchair-skills capacity, retain those improvements at one year and improve participation in comparison with an Educational Control (EC) group. METHODS: We carried out a randomized controlled trial, studying 106 veterans with SCI from three Veterans Affairs rehabilitation centers...
2016: PloS One
https://www.readbyqxmd.com/read/27999362/body-machine-interfaces-after-spinal-cord-injury-rehabilitation-and-brain-plasticity
#19
Ismael Seáñez-González, Camilla Pierella, Ali Farshchiansadegh, Elias B Thorp, Xue Wang, Todd Parrish, Ferdinando A Mussa-Ivaldi
The purpose of this study was to identify rehabilitative effects and changes in white matter microstructure in people with high-level spinal cord injury following bilateral upper-extremity motor skill training. Five subjects with high-level (C5-C6) spinal cord injury (SCI) performed five visuo-spatial motor training tasks over 12 sessions (2-3 sessions per week). Subjects controlled a two-dimensional cursor with bilateral simultaneous movements of the shoulders using a non-invasive inertial measurement unit-based body-machine interface...
December 19, 2016: Brain Sciences
https://www.readbyqxmd.com/read/27995945/the-developing-landscape-of-diagnostic-and-prognostic-biomarkers-for-spinal-cord-injury-in-cerebrospinal-fluid-and-blood
#20
REVIEW
C H Hulme, S J Brown, H R Fuller, J Riddell, A Osman, J Chowdhury, N Kumar, W E Johnson, K T Wright
STUDY DESIGN: Review study. OBJECTIVES: The identification of prognostic biomarkers of spinal cord injury (SCI) will help to assign SCI patients to the correct treatment and rehabilitation regimes. Further, the detection of biomarkers that predict permanent neurological outcome would aid in appropriate recruitment of patients into clinical trials. The objective of this review is to evaluate the current state-of-play in this developing field. SETTING: Studies from multiple countries were included...
December 20, 2016: Spinal Cord
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