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Spinal cord injury rehabilitation

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https://www.readbyqxmd.com/read/27919862/spinal-cord-injury-assessing-tolerability-and-use-of-combined-rehabilitation-and-neuroaid-saturn-study-protocol-of-an-exploratory-study-in-assessing-the-safety-and-efficacy-of-neuroaid-amongst-people-who-sustain-severe-spinal-cord-injury
#1
Ramesh Kumar, Ohnmar Htwe, Azmi Baharudin, Mohammad Hisam Ariffin, Shaharuddin Abdul Rhani, Kamalnizat Ibrahim, Aishah Rustam, Robert Gan
BACKGROUND: Spinal cord injury (SCI) is a devastating condition with limited therapeutic options despite decades of research. Current treatment options include use of steroids, surgery, and rehabilitation. Nevertheless, many patients with SCI remain disabled. MLC601 (NeuroAiD), a combination of natural products, has been shown to be safe and to aid neurological recovery after brain injuries and may have a potential role in improving recovery after SCI. OBJECTIVE: The aim of this study is to evaluate the safety and efficacy of NeuroAiD amongst people who sustain SCI in the study setting...
December 5, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27917686/physical-activity-promotion-for-people-with-spinal-cord-injury-physiotherapists-beliefs-and-actions
#2
Toni L Williams, Brett Smith, Anthony Papathomas
PURPOSE: It is vital that people with spinal cord injury (SCI) lead a physically active lifestyle to promote long term health and well-being. Yet within rehabilitation and upon discharge into the community, people with SCI are largely inactive. Physiotherapists are well placed to promote a physically active lifestyle and are valued and trusted messengers of physical activity (PA) by people with SCI. Therefore this study aimed to explore the perceptions of physiotherapists in SCI rehabilitation on PA for people with SCI, and what is done to promote PA...
December 5, 2016: Disability and Rehabilitation
https://www.readbyqxmd.com/read/27913797/promoting-gait-recovery-and-limiting-neuropathic-pain-after-spinal-cord-injury-two-sides-of-the-same-coin
#3
Catherine Mercier, Meyke Roosink, Jason Bouffard, Laurent J Bouyer
Most persons living with a spinal cord injury experience neuropathic pain in the months following their lesion, at the moment where they receive intensive gait rehabilitation. Based on studies using animal models, it has been proposed that central sensitization in nociceptive pathways (maladaptive plasticity) and plasticity related to motor learning (adaptive plasticity) share common neural mechanisms and compete with each other. This article aims to address the discrepancy between the growing body of basic science literature supporting this hypothesis and the general belief in rehabilitation research that pain and gait rehabilitation represent two independent problems...
December 2, 2016: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/27911071/severe-brain-injury-in-massachusetts-assessing-the-continuum-of-care
#4
Laura Lorenz, Gabrielle Katz
Acquired brain injury (ABI) is a major public health problem in Massachusetts (Hackman et al, 2014) and includes traumatic brain injury (TBI), stroke, ABI-related infectious diseases, metabolic disorders affecting the central nervous system (brain and spinal cord), and brain tumor. Advances in emergency medical care and neurosurgery mean that more people are surviving severe traumatic brain injury (Trexler et al, 2014). Yet many patients with severe TBI in particular, are not receiving inpatient services after initial treatment (Hackman et al, 2014; CDC, 2014) or later that are known to be effective (Malec & Kean, 2015; Lewis & Horn, 2015; BI Commission, 2011; Kolakowsky-Hayner et al, 2000; Interviews)...
December 10, 2015: Issue Brief
https://www.readbyqxmd.com/read/27901413/dose-response-outcomes-associated-with-different-forms-of-locomotor-training-in-persons-with-chronic-motor-incomplete-spinal-cord-injury
#5
Evan Blake Sandler, Kathryn E Roach, Edelle C Field-Fote
Outcomes of training are thought to be related to amount of training (training dose). While various approaches to locomotor training have been used to improve walking function in persons with spinal cord injury, little is known about the relationship between dose of locomotor training and walking outcomes. This secondary analysis aimed to identify the relationship between training dose and improvement in walking distance and speed associated with the largest randomized clinical trial to date of locomotor training in participants with chronic motor-incomplete spinal cord injury (MISCI)...
November 30, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27897188/community-participation-for-individuals-with-spinal-cord-injury-living-in-queensland-australia
#6
J J Carr, M B Kendall, D I Amsters, K J Pershouse, P Kuipers, P Buettner, R N Barker
STUDY DESIGN: Sequential mixed method design. OBJECTIVES: Determine factors associated with community participation for individuals with spinal cord injury (SCI). SETTING: Queensland, Australia. METHODS: Phase I consisted of a quantitative telephone survey of 270 people who had sustained a SCI within the past 50 years. To verify and interpret survey findings, Phase II involved a qualitative investigation. One focus group, one dyadic and one in-depth interview were conducted with a separate sample of eight people who had sustained a SCI within the past 50 years...
November 29, 2016: Spinal Cord
https://www.readbyqxmd.com/read/27889817/paediatric-spinal-cord-infarction-a-review-of-the-literature-and-two-case-reports
#7
Asim Sheikh, Daniel Warren, Anne-Marie Childs, John Russell, Mark Liddington, Velupandian Guruswamy, Paul Chumas
Ischemic spinal cord infarction is rare in the paediatric population, and when it does occur, it is usually associated with traumatic injury. Other potential causes include congenital cardiovascular malformations, cerebellar herniation, thromboembolic disease and infection. Magnetic resonance imaging (MRI) findings can be subtle in the early evaluation of such patients. The outcome is variable and depends on the level and extent of the spinal cord infarct and subsequent rehabilitation. Here, we present two cases of ischemic spinal cord infarction in children...
November 26, 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27886883/restorative-treatments-for-spinal-cord-injury
#8
REVIEW
Stephanie Chen, Allan D Levi
Spinal cord injury remains an incurable disease with an enormous impact functionally, financially, and emotionally on affected individuals and their families. Current treatment modalities are focused on minimizing secondary injury and maximizing residual function via rehabilitation. In this article, the authors discuss ambitious advancements under investigation aimed at restoring function. These promising experimental treatments focus on neuroprotection with hypothermia and pharmacologic therapies, regeneration via cell transplantation, and rewiring with electrical stimulation...
January 2017: Neurosurgery Clinics of North America
https://www.readbyqxmd.com/read/27881040/a-single-dose-of-docosahexaenoic-acid-increases-the-functional-recovery-promoted-by-rehabilitation-following-cervical-spinal-cord-injury-in-the-rat
#9
Zhuo-Hao Liu, Ping Yip, John V Priestley, Adina T Michael-Titus
Task-specific rehabilitation has been shown to promote functional recovery after acute spinal cord injury (SCI). Recently, the omega-3 polyunsaturated fatty acid, docosahexaenoic acid (DHA), has been shown to promote neuroplasticity after SCI. Here, we investigated whether the combination of a single bolus of DHA with rehabilitation can enhance the effect of DHA or rehabilitation therapy in adult injured spinal cord. We found enhanced functional improvement with DHA in combination with rehabilitation compared to either treatment alone in a rat cervical lateral hemisection SCI model...
November 23, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27875927/what-is-being-trained-how-divergent-forms-of-plasticity-compete-to-shape-locomotor-recovery-after-spinal-cord-injury
#10
J Russell Huie, Kazuhito Morioka, Jenny Haefeli, Adam R Ferguson
Spinal cord injury (SCI) is a devastating syndrome that produces dysfunction in motor and sensory systems, manifesting as chronic paralysis, sensory changes, and pain disorders. The multifaceted and heterogeneous nature of SCI has made effective rehabilitative strategies challenging. Work over the last 40 years has aimed to overcome these obstacles by harnessing the intrinsic plasticity of the spinal cord to improve functional locomotor recovery. Intensive training after SCI facilitates lower extremity function and has shown promise as a tool for retraining the spinal cord by engaging innate locomotor circuitry in the lumbar cord...
November 22, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27873553/real-time-control-of-an-exoskeleton-hand-robot-with-myoelectric-pattern-recognition
#11
Zhiyuan Lu, Xiang Chen, Xu Zhang, Kay-Yu Tong, Ping Zhou
Robot-assisted training provides an effective approach to neurological injury rehabilitation. To meet the challenge of hand rehabilitation after neurological injuries, this study presents an advanced myoelectric pattern recognition scheme for real-time intention-driven control of a hand exoskeleton. The developed scheme detects and recognizes user's intention of six different hand motions using four channels of surface electromyography (EMG) signals acquired from the forearm and hand muscles, and then drives the exoskeleton to assist the user accomplish the intended motion...
October 6, 2016: International Journal of Neural Systems
https://www.readbyqxmd.com/read/27871967/prevalence-and-etiology-of-hypogonadism-in-young-men-with-chronic-spinal-cord-injury-a-cross-sectional-analysis-from-two-university-based-rehabilitation-centers
#12
Shannon D Sullivan, Mark S Nash, Eshetu Tefera, Emily Tinsley, Marc R Blackman, Suzanne Groah
BACKGROUND: Spinal cord injury (SCI) triggers an 'accelerated aging' process that may include development of hypogonadism, even among younger men with SCI; however, few studies have investigated the prevalence or etiology of hypogonadism in men with SCI. Young men with SCI are also at increased risk for developing metabolic dysfunction after injury, which may be exacerbated by concomitant testosterone (T) deficiency, thus identifying the prevalence and risk factors for T deficiency in men with SCI is important for their long-term health...
November 18, 2016: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/27863746/biophysical-skin-properties-of-grade-1-pressure-ulcers-and-unaffected-skin-in-spinal-cord-injured-and-able-bodied-persons-in-the-unloaded-sacral-region
#13
Anke Scheel-Sailer, Angela Frotzler, Gabi Mueller, Simon Annaheim, René Michel Rossi, Siegfried Derler
AIM OF THE STUDY: To examine biophysical skin properties in the sacral region in spinal cord injury (SCI) patients suffering from a grade 1 pressure ulcer (PU) defined as non-blanchable erythema (SCI/PU), SCI patients in the post-acute phase (SCI/PA) and able-bodied participants (CON). Also, for SCI/PU patients, both the affected skin and healthy skin close to the PU were examined. STUDY DESIGN: An experimental controlled study with a convenience sample. SETTING: A Swiss acute care and rehabilitation clinic specializing in SCIs...
November 8, 2016: Journal of Tissue Viability
https://www.readbyqxmd.com/read/27863455/what-did-we-learn-from-the-animal-studies-of-body-weight-supported-treadmill-training-and-where-do-we-go-from-here
#14
Ray de Leon, Christine Dy
Body weight supported treadmill training (BWSTT) developed from animal studies of spinal cord injury (SCI). Evidence that spinal cats, i.e. cats that have a complete surgical transection of the cord, could regain the ability to step on a moving treadmill indicated a vast potential for spinal circuits to generate walking without the brain. BWSTT represented a means to unlock that potential. As the technique was adapted as a rehabilitation intervention for humans with SCI, shortcomings in the translation to walking in the real world were exposed...
November 18, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27857906/current-concept-of-stem-cell-therapy-for-spinal-cord-injury-a-review
#15
REVIEW
Sun Kyu Oh, Sang Ryong Jeon
Spinal cord injury (SCI) is a catastrophic condition associated with significant neurological deficit, social, and financial burdens. Over the past decades, various treatments including medication, surgery, and rehabilitation therapy for SCI have been performed, but there were no definite treatment option to improve neurological function of patients with chronic SCI. Therefore, new treatment trials with stem cells have been studied to regenerate injured spinal cord. Among various types of stem cells, bone marrow derived mesenchymal stem cells is highly expected as candidates for the stem cell therapy...
October 2016: Korean Journal of Neurotrauma
https://www.readbyqxmd.com/read/27853668/the-effectiveness-and-safety-of-exoskeletons-as-assistive-and-rehabilitation-devices-in-the-treatment-of-neurologic-gait-disorders-in-patients-with-spinal-cord-injury-a-systematic-review
#16
Christian Fisahn, Mirko Aach, Oliver Jansen, Marc Moisi, Angeli Mayadev, Krystle T Pagarigan, Joseph R Dettori, Thomas A Schildhauer
Study Design Systematic review. Clinical Questions (1) When used as an assistive device, do wearable exoskeletons improve lower extremity function or gait compared with knee-ankle-foot orthoses (KAFOs) in patients with complete or incomplete spinal cord injury? (2) When used as a rehabilitation device, do wearable exoskeletons improve lower extremity function or gait compared with other rehabilitation strategies in patients with complete or incomplete spinal cord injury? (3) When used as an assistive or rehabilitation device, are wearable exoskeletons safe compared with KAFO for assistance or other rehabilitation strategies for rehabilitation in patients with complete or incomplete spinal cord injury? Methods PubMed, Cochrane, and Embase databases and reference lists of key articles were searched from database inception to May 2, 2016, to identify studies evaluating the effectiveness of wearable exoskeletons used as assistive or rehabilitative devices in patients with incomplete or complete spinal cord injury...
December 2016: Global Spine Journal
https://www.readbyqxmd.com/read/27852160/predictors-of-functional-outcomes-in-adults-with-traumatic-spinal-cord-injury-following-inpatient-rehabilitation-a-systematic-review
#17
Faisal AlHuthaifi, Joseph Krzak, Timothy Hanke, Lawrence C Vogel
CONTEXT: Despite functional improvements during rehabilitation, variable functional outcomes were reported when patients with Spinal Cord Injury (SCI) return to society. Higher functioning individuals at discharge can experience a decrease in independent mobility (i.e. Motor Functional Independence Measure (mFIM) Score) by one-year follow-up. However, functional gains after discharge have also been reported and associated with recovery. OBJECTIVE: To identify, categorize and rank predictors of mFIM score for patients with SCI following inpatient rehabilitation, both at the time of discharge and at one-year follow-up...
November 17, 2016: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/27846851/physical-activity-outside-of-structured-therapy-during-inpatient-spinal-cord-injury-rehabilitation
#18
Dominik Zbogar, Janice J Eng, William C Miller, Andrei V Krassioukov, Mary C Verrier
BACKGROUND: Little information exists on the content of inpatient rehabilitation stay when individuals with spinal cord injury (SCI) are not engaged in structured rehabilitation therapy sessions. Investigation of inpatient therapy content is incomplete without the context of activities outside of this time. We sought to quantify physical activity occurring outside of physical therapy (PT) and occupational therapy (OT) sessions during inpatient SCI rehabilitation and examine how this activity changes over time from admission to discharge...
November 15, 2016: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/27845357/participation-in-activities-and-secondary-health-complications-among-persons-aging-with-traumatic-spinal-cord-injury
#19
U Lundström, K Wahman, Å Seiger, D B Gray, G Isaksson, M Lilja
STUDY DESIGN: Cross-sectional study. OBJECTIVES: To describe participation in activities and explore the relationship with secondary complications among persons aging with a traumatic spinal cord injury (SCI). SETTING: A regional SCI outpatient center in Sweden. METHODS: Data were collected through a phone survey, which included 10 activities from the instrument PARTS/M-v3 (PARTicipation Survey/Mobility version-3) together with data from the participants' medical records...
November 15, 2016: Spinal Cord
https://www.readbyqxmd.com/read/27845356/perceived-effectiveness-and-mechanisms-of-community-peer-based-programmes-for-spinal-cord-injuries-a-systematic-review-of-qualitative-findings
#20
REVIEW
A Divanoglou, M Georgiou
STUDY DESIGN: Systematic review and meta-synthesis of qualitative findings. OBJECTIVES: To establish the perceived effectiveness and mechanisms of community peer-based programmes based on narratives of consumers with spinal cord injury (SCI). METHODS: Scopus, Academic Search Complete, CINAHL, Health Source, Medline, PsycARTICLES, PsychINFO, SPORTSDiscus and ProQuest were searched for articles published in English between January 1990 and December 2015...
November 15, 2016: Spinal Cord
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