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Geriatric syndrome

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https://www.readbyqxmd.com/read/29774174/outpatient-interventions-that-may-enhance-the-care-of-a-patient-with-co-existing-moyamoya-and-down-syndromes
#1
Anita Lwanga, Waldo Herrera, Katya Cruz Madrid, Antony Irungu
Moyamoya vasculopathy is a condition of chronic, progressive occlusion of the distal internal carotid arteries and the Circle of Willis. The resultant ischemia produces compensatory angiogenesis and the growth of a network of collateral blood vessels, which on angiography resemble a "puff of smoke" or "moyamoya" in Japanese. The objective of this case report is to describe the clinical course of a patient with Down and moyamoya syndromes and to enlighten clinicians about strategies that can be taken to enhance the care of similar patients...
March 16, 2018: Curēus
https://www.readbyqxmd.com/read/29768372/technologies-for-participatory-medicine-and-health-promotion-in-the-elderly-population
#2
Laura Nieto-Riveiro, Betania Groba, M Carmen Miranda, Patricia Concheiro, Alejandro Pazos, Thais Pousada, Javier Pereira
INTRODUCTION: The progressive aging of the population is a socio-demographic phenomenon experienced by most countries in the world in recent decades, especially in Japan and in many European Union countries. During this process, so-called "geriatric syndromes" frequently occur. The focus of this study is the quality of life of the elderly in relation to these 3 factors: risk of falls, urinary incontinence, and insomnia. OBJECTIVE: The main purpose is to determine the impact of a multifactorial intervention program implemented with institutionalized elderly people...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29745482/-%C3%A2-it-s-normal-to-get-old-and-weak-%C3%A2-should-functional-decline-be-addressed-with-elderly-patients-in-family-medicine
#3
Ophélie Viret, Joëlle Schwarz, Nicolas Senn, Yolanda Mueller
Among the health strategies to respond to the aging of the population, initiatives for the screening and management of age-related health issues are implemented, including in family medicine. Preliminary results of a qualitative study suggest that elderly people are ambivalent about anticipating age-related issues, tend to trivialize them and to be reluctant to discuss them spontaneously with their doctors. However, they find relevant that their family doctor brings up the topic with specific questions, because that allows initiating a discussion about some of these sensitive issue...
May 9, 2018: Revue Médicale Suisse
https://www.readbyqxmd.com/read/29741193/identifying-exosome-derived-micrornas-as-candidate-biomarkers-of-frailty
#4
B R Ipson, M B Fletcher, S E Espinoza, A L Fisher
Frailty is a geriatric syndrome associated with progressive physical decline and significantly increases risk for falls, disability, hospitalizations, and death. However, much remains unknown regarding the biological mechanisms that contribute to aging and frailty, and to date, there are no clinically used prognostic or diagnostic molecular biomarkers. The present study profiled exosome-derived microRNAs isolated from the plasma of young, robust older, and frail older individuals and identified eight miRNAs that are uniquely enriched in frailty: miR-10a-3p, miR-92a-3p, miR-185-3p, miR-194-5p, miR-326, miR-532-5p, miR-576-5p, and miR-760...
2018: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29739428/incidence-and-outcomes-of-acute-kidney-injury-in-octogenarians-in-jordan
#5
Ashraf O Oweis, Sameeha A Alshelleh
OBJECTIVE: Improvements in the health care system, resulted in a greater number of geriatric patients diagnosed with acute kidney injury (AKI). We evaluated the incidence and outcome of AKI in octogenarians, as studies in the Middle-East region are few; moreover, treatment approaches, in addition to medical decisions, may require special consideration for advanced age to improve the outcomes. RESULTS: At King Abdullah II teaching and referral hospital, we recruited patients aged 80-90 years who were admitted to the medical floor between January 2010 and December 2013...
May 8, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29734698/disparate-habitual-physical-activity-and-dietary-intake-profiles-of-elderly-men-with-low-and-elevated-systemic-inflammation
#6
Dimitrios Draganidis, Athanasios Z Jamurtas, Theodoros Stampoulis, Vasiliki C Laschou, Chariklia K Deli, Kalliopi Georgakouli, Konstantinos Papanikolaou, Athanasios Chatzinikolaou, Maria Michalopoulou, Constantinos Papadopoulos, Panagiotis Tsimeas, Niki Chondrogianni, Yiannis Koutedakis, Leonidas G Karagounis, Ioannis G Fatouros
The development of chronic, low-grade systemic inflammation in the elderly (inflammaging) has been associated with increased incidence of chronic diseases, geriatric syndromes, and functional impairments. The aim of this study was to examine differences in habitual physical activity (PA), dietary intake patterns, and musculoskeletal performance among community-dwelling elderly men with low and elevated systemic inflammation. Nonsarcopenic older men free of chronic diseases were grouped as ‘low’ (LSI: n = 17; 68...
May 4, 2018: Nutrients
https://www.readbyqxmd.com/read/29730710/frailty-in-hematologic-malignancy
#7
REVIEW
Thuy T Koll, Ashley E Rosko
PURPOSE OF REVIEW: Older adults with hematologic malignancy are a growing demographic. Estimating risk of chemotherapy toxicity based on age alone is an unreliable estimate of quality of life, functional capacity, or risk of treatment complications. RECENT FINDINGS: Dedicated geriatric assessment tools can aid the clinician in identifying geriatric syndromes such as frailty, resulting in improved prognostication to decrease morbidity and mortality. Frailty is not synonymous with individual performance status and is dynamic...
May 5, 2018: Current Hematologic Malignancy Reports
https://www.readbyqxmd.com/read/29720298/addressing-the-shortage-of-geriatric-specialists
#8
Casandra A Holveck, Jeannette Y Wick
With a population that is increasingly "gray," our nation faces a shortage of primary care providers who specialize in geriatrics. The number of geriatricians per 10,000 adults older than 65 years of age has decreased steadily since 2000. Health care providers from all disciplines (medicine, nursing, and pharmacy) tend not to choose geriatrics as a specialty area. Some are intimidated by the complexity of caring for elderly patients with geriatric syndromes and multiple morbidities. Others, who have little exposure to geriatrics in their undergraduate and graduate programs, are simply unaware of the personal and professional rewards associated with practice in geriatrics...
March 1, 2018: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
https://www.readbyqxmd.com/read/29717762/adherence-to-the-mediterranean-diet-and-the-risk-of-frailty-in-old-people-a-systematic-review-and-meta-analysis
#9
Y Wang, Q Hao, L Su, Y Liu, S Liu, B Dong
BACKGROUND: Frailty is a common geriatric syndrome in old people. It remains controversial whether Mediterranean diet could prevent old people from developing into frailty. The aim of this study is to summarize the relevant studies and assess the effectiveness of adherence to Mediterranean diet on frailty in old people. METHOD: A systematic search of MEDLINE, EMBASE and Cochrane Central Register of Controlled Trials was conducted to identify all relevant studies up to Oct 2017...
2018: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29701640/wearable-sensors-and-the-assessment-of-frailty-among-vulnerable-older-adults-an-observational-cohort-study
#10
Javad Razjouyan, Aanand D Naik, Molly J Horstman, Mark E Kunik, Mona Amirmazaheri, He Zhou, Amir Sharafkhaneh, Bijan Najafi
Background: The geriatric syndrome of frailty is one of the greatest challenges facing the U.S. aging population. Frailty in older adults is associated with higher adverse outcomes, such as mortality and hospitalization. Identifying precise early indicators of pre-frailty and measures of specific frailty components are of key importance to enable targeted interventions and remediation. We hypothesize that sensor-derived parameters, measured by a pendant accelerometer device in the home setting, are sensitive to identifying pre-frailty...
April 26, 2018: Sensors
https://www.readbyqxmd.com/read/29699938/black-white-disparity-in-physical-performance-among-older-women-with-newly-diagnosed-non-metastatic-breast-cancer-exploring-the-role-of-inflammation-and-physical-activity
#11
Cynthia Owusu, Mark Schluchter, Siran M Koroukian, Kathryn H Schmitz, Nathan A Berger
OBJECTIVE: To examine racial differences in physical performance among older women with newly diagnosed non-metastatic breast cancer and identify clinical, behavioral and biological factors that might contribute to such disparities. METHODS: This is a cross-sectional study of women aged ≥65 years with newly diagnosed stage I-III breast cancer recruited from ambulatory oncology clinics at an academic center, between September 2010 and August 2015. Participants completed a Comprehensive Geriatric Assessment and laboratory testing for biomarkers of inflammation [interleukin-6 (IL6)] prior to receiving systemic treatment for cancer...
April 23, 2018: Journal of Geriatric Oncology
https://www.readbyqxmd.com/read/29694263/the-decrease-in-phase-angle-measured-by-bioelectrical-impedance-analysis-reflects-the-increased-locomotive-syndrome-risk-in-community-dwelling-people-the-yakumo-study
#12
Satoshi Tanaka, Kei Ando, Kazuyoshi Kobayashi, Tetsuro Hida, Taisuke Seki, Takashi Hamada, Kenyu Ito, Mikito Tsushima, Masayoshi Morozumi, Masaaki Machino, Kyotaro Ota, Naoki Ishiguro, Yukiharu Hasegawa, Shiro Imagama
OBJECTIVES: The locomotive syndrome (LS) risk test has recently been advocated for the evaluation of physical ability. Phase angle measurement by bioelectrical impedance analysis (BIA) is an indicator of cellular health and muscle mass. We aimed to investigate how muscle mass and phase angle are related to LS risk stage. METHODS: A prospective cohort study was conducted in 311 patients who were undergoing a health checkup. All participants performed the two-step test, stand-up test, and 25-question geriatric locomotive function scale components of the LS risk test...
April 25, 2018: Modern Rheumatology
https://www.readbyqxmd.com/read/29683237/establishing-a-proactive-geriatrician-led-comprehensive-geriatric-assessment-in-older-emergency-surgery-patients-outcomes-of-a-pilot-study
#13
Matthew C Mason, Amy L Crees, Matthew R Dean, Nahida Bashir
INTRODUCTION: Increasing numbers of older adults are presenting with acute surgical disease to the unselected general surgical take. General surgeons have little training to manage these patients. We developed a pilot service of proactive geriatrician input into older emergency general surgical patients in a single institution. We wanted to demonstrate if geriatricians improve the management of these patients. METHODS: Patients aged 70 years or older admitted acutely under the general surgeons were assessed proactively by a geriatrician using comprehensive geriatric assessment (CGA)...
April 23, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29676874/-screening-of-frailty-in-the-emergency-unit-myth-or-reality
#14
A A Zulfiqar
At present, it is recognized that screening for frailty in the elderly is a major public health issue. Frailty screening in emergency unit is essential to optimize the management of elderly patients in hospital. Ideally, the role of a mobile geriatric team seems essential, taking over the frailty screening carried out in the emergency department, in order to optimize intra-hospital management and consequently reduce further intra-hospital visits and possible risks of decompensation of geriatric syndromes.
April 2018: Revue Médicale de Liège
https://www.readbyqxmd.com/read/29673895/direct-costs-of-very-old-persons-with-subsyndromal-depression-a-5-year-prospective-study
#15
Mikael Ludvigsson, Lars Bernfort, Jan Marcusson, Ewa Wressle, Anna Milberg
OBJECTIVES: This study aimed to compare, over a 5-year period, the prospective direct healthcare costs and service utilization of persons with subsyndromal depression (SSD) and non-depressive persons (ND), in a population of very old persons. A second aim was to develop a model that predicts direct healthcare costs in very old persons with SSD. DESIGN AND SETTING: A prospective population-based study was undertaken on 85-year-old persons in Sweden. MEASUREMENTS: Depressiveness was screened with the Geriatric Depression Scale at baseline and at 1-year follow-up, and the results were classified into ND, SSD, and syndromal depression...
March 15, 2018: American Journal of Geriatric Psychiatry
https://www.readbyqxmd.com/read/29673832/effects-of-physical-training-with-the-nintendo-wii-fit-plus-%C3%A2-and-protein-supplementation-on-musculoskeletal-function-and-the-risk-of-falls-in-pre-frail-older-women-protocol-for-a-randomized-controlled-clinical-trial-the-wiiprotein-study
#16
Audrin Said Vojciechowski, Simone Biesek, Jarbas Melo Filho, Estela Iraci Rabito, Maryelle Paula do Amaral, Anna Raquel Silveira Gomes
BACKGROUND: Frailty is one of the key geriatric syndromes and is related to the loss of functional independence. However, the practice of physical training (PT) combined with protein supplementation (PS) may improve musculoskeletal function (MF). OBJECTIVE: To verify the effect of PT using 'exergames' with or without PS on MF, nutritional status, and risk of falls in pre-frail older women. METHOD: The protocol is for a randomized controlled clinical trial with a sample of pre-frail older women, divided into 5 groups: control group; PT using exergames; PS; PT using exergames combined with PS; PT using exergames combined with isoenergetic supplementation...
May 2018: Maturitas
https://www.readbyqxmd.com/read/29671037/-geriatric-intensive-care-patients-perspectives-and-limits-of-geriatric-intensive-care-medicine
#17
REVIEW
U Müller-Werdan, H-J Heppner, G Michels
Critically ill geriatric patients are vitally endangered due to the aging processes of organs, the frequently existing multimorbidity with subsequent polypharmacy and the typical geriatric syndrome of functional impairments. Aging processes in organs lower the clinical threshold for organ dysfunction and organ failure. Physiological organ aging processes with practical consequences for intensive care medicine are atypical manifestion of sepsis in immunosenescence, altered pharmacokinetics, reduced tolerance to hypovolemia due to proportionally reduced water compartment of the body in old age, the frequently only apparently normal function of the kidneys and the continuous reduction in pulmonary function in old age...
April 18, 2018: Medizinische Klinik, Intensivmedizin und Notfallmedizin
https://www.readbyqxmd.com/read/29662881/the-continuum-of-aging-and-age-related-diseases-common-mechanisms-but-different-rates
#18
REVIEW
Claudio Franceschi, Paolo Garagnani, Cristina Morsiani, Maria Conte, Aurelia Santoro, Andrea Grignolio, Daniela Monti, Miriam Capri, Stefano Salvioli
Geroscience, the new interdisciplinary field that aims to understand the relationship between aging and chronic age-related diseases (ARDs) and geriatric syndromes (GSs), is based on epidemiological evidence and experimental data that aging is the major risk factor for such pathologies and assumes that aging and ARDs/GSs share a common set of basic biological mechanisms. A consequence is that the primary target of medicine is to combat aging instead of any single ARD/GSs one by one, as favored by the fragmentation into hundreds of specialties and sub-specialties...
2018: Frontiers in Medicine
https://www.readbyqxmd.com/read/29652197/relationship-between-locomotive-syndrome-and-body-composition-among-community-dwelling-middle-age-and-elderly-individuals-in-japan-the-yakumo-study
#19
Satoshi Tanaka, Kei Ando, Kazuyoshi Kobayashi, Tetsuro Hida, Taisuke Seki, Koji Suzuki, Kenyu Ito, Mikito Tsushima, Masayoshi Morozumi, Masaaki Machino, Kyotaro Ota, Naoki Ishiguro, Yukiharu Hasegawa, Shiro Imagama
OBJECTIVES: Locomotive syndrome (LS) is a condition requiring nursing care for musculoskeletal disorders. Our aim was to evaluate the correlation between body composition, measured by bioelectrical impedance analysis (BIA), and LS, measured using the 25-question Geriatric Locomotive Functional Scale (GLFS-25). METHODS: We enrolled 286 individuals who were undergoing regular health follow-up. All individuals completed the GLFS-25, body composition analysis by BIA, and five physical performance tests related to LS: Timed up-and-go test, 10-m gait time, maximum stride length, back strength, and grip strength...
April 13, 2018: Modern Rheumatology
https://www.readbyqxmd.com/read/29643004/association-between-mediterranean-diet-and-hand-grip-strength-in-older-adult-women
#20
Luigi Barrea, Giovanna Muscogiuri, Carolina Di Somma, Giovanni Tramontano, Vincenzo De Luca, Maddalena Illario, Annamaria Colao, Silvia Savastano
BACKGROUND & AIMS: Mediterranean Diet (MD) is an eating pattern associated with multiple healthy benefits, including the conservation of skeletal muscle. Frailty is a major geriatric syndrome characterized by low muscle strength. The Hand Grip Strength (HGS) is the most frequently used indicator of muscle functional capacity for clinical purposes. The association between the adherence to the MD and HGS in elderly has not yet fully investigated. The goal of this study was to examine the association between the adherence to the MD and HGS in a not hospitalized elderly who participated in the project PERsonalised ict Supported Services for Independent Living and Active Ageing (PERSSILAA)...
April 3, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
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