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https://www.readbyqxmd.com/read/28338565/corneal-nerve-morphology-sensitivity-and-tear-neuropeptides-in-contact-lens-wear
#1
Blanka Golebiowski, Cecilia Chao, Fiona Stapleton, Isabelle Jalbert
PURPOSE: To determine tear neuropeptide levels in contact lens wearers and non-wearers, and to examine relationships with indices of corneal innervation, tear function, and ocular discomfort. METHODS: A cross-sectional, single-visit, investigator-masked pilot study. Assessments included Ocular Comfort Index (OCI), central and mid-peripheral corneal nerve density and morphology (HRT-Rostock), corneal sensitivity (Cochet-Bonnet aesthesiometer), tear Substance P and calcitonin gene-related peptide (CGRP) concentration (ELISA), in situ tear osmolarity (TearLab), tear secretion (Phenol Red Thread), and noninvasive tear break-up time (NITBUT; Keeler Tearscope)...
April 2017: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/28333960/effect-of-the-dilution-rate-on-microbial-competition-r-strategist-can-win-over-k-strategist-at-low-substrate-concentration
#2
Mari-K H Winkler, Pieter Boets, Birk Hahne, Peter Goethals, Eveline I P Volcke
The conditions present in both in vitro and in vivo ecosystems determine the microbial population harbouring it. One commonly accepted theory is that a species with a high substrate affinity and low growth rate (k-strategist) will win the competition against a second species with a lower substrate affinity and higher growth rate (r-strategist) if both species are subjected to low substrate concentrations. In this study two nitrite oxidizing bacteria (NOB), Nitrospira defluvii (k-strategist) and Nitrobacter vulgaris (r-strategist), were cultivated in a continuous reactor systems...
2017: PloS One
https://www.readbyqxmd.com/read/28333092/impact-of-coagulant-and-flocculant-addition-to-an-anaerobic-dynamic-membrane-bioreactor-andmbr-treating-waste-activated-sludge
#3
Guido Kooijman, Wilton Lopes, Zhongbo Zhou, Hongxiao Guo, Merle de Kreuk, Henri Spanjers, Jules van Lier
In this work, we investigated the effects of flocculation aid (FA) addition to an anaerobic dynamic membrane bioreactor (AnDMBR) (7 L, 35 °C) treating waste-activated sludge (WAS). The experiment consisted of three distinct periods. In period 1 (day 1-86), the reactor was operated as a conventional anaerobic digester with a solids retention time (SRT) and hydraulic retention time (HRT) of 24 days. In period 2 (day 86-303), the HRT was lowered to 18 days with the application of a dynamic membrane while the SRT was kept the same...
March 23, 2017: Membranes
https://www.readbyqxmd.com/read/28332872/characterization-of-spontaneous-and-induced-puberty-in-girls-with-turner-syndrome
#4
Lisal J Folsom, James E Slaven, Zeina M Nabhan, Erica A Eugster
OBJECTIVE: To characterize puberty in girls with Turner syndrome, and determine whether specific patient characteristics are associated with the timing of menarche. We also sought to compare spontaneous vs. induced puberty in these patients. DESIGN/PATIENTS/MEASUREMENTS: Medical records of girls followed in our Pediatric Endocrine clinic for Turner syndrome from 2007 to 2015 were reviewed. RESULTS: Fifty-three girls were included, of whom 10 (19%) achieved menarche spontaneously and 43 (81%) received hormone replacement therapy (HRT)...
March 23, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28330191/biodegradation-of-4-chlorophenol-in-an-airlift-inner-loop-bioreactor-with-mixed-consortium-effect-of-hrt-loading-rate-and-biogenic-substrate
#5
Bhishma P Patel, Arvind Kumar
In the present work, removal of 4-chlorophenol (4-CP) by the mixed microbial consortium was evaluated in an airlift inner loop bioreactor. During the study, the effect of various reactor parameters such as hydraulic retention time (HRT), biogenetic substrate concentration, loading rate, and initial substrate concentration on the removal efficiency of 4-CP was investigated. Bioreactor showed a maximum removal rate of 16.59 mg/L/h at the optimum conditions of 24 h HRT, 400 mg/L initial 4-CP, and 0.2 g/L peptone...
December 2016: 3 Biotech
https://www.readbyqxmd.com/read/28326039/estrone-sulfate-transport-and-steroid-sulfatase-activity-in-colorectal-cancer-implications-for-hormone-replacement-therapy
#6
Lorna C Gilligan, Ali Gondal, Vivien Tang, Maryam T Hussain, Anastasia Arvaniti, Anne-Marie Hewitt, Paul A Foster
Hormone replacement therapy (HRT) affects the incidence and potential progression of colorectal cancer (CRC). As HRT primarily consists of estrone sulfate (E1S), understanding whether this conjugated estrogen is transported and metabolized in CRC will define its potential effect in this malignancy. Here, we show that a panel of CRC cell lines (Colo205, Caco2, HCT116, HT-29) have steroid sulfatase (STS) activity, and thus can hydrolyze E1S. STS activity is significantly higher in CRC cell lysate, suggesting the importance of E1S transport in intracellular STS substrate availability...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28324826/nitrogen-removal-by-the-enhanced-floating-treatment-wetlands-from-the-secondary-effluent
#7
Lei Gao, Weili Zhou, Jungchen Huang, Shengbing He, Yijia Yan, Wenying Zhu, Suqing Wu, Xu Zhang
Three novel floating treatment wetlands, including autotrophic enhanced floating treatment wetland (AEFTW), heterotrophic enhanced floating treatment wetland (HEFTW) and enhanced floating treatment wetland (EFTW) were developed to remove nitrogen from the secondary effluent. Results showed that the analogously excellent nitrogen removal performance was achieved in AEFTW and HEFTW. About 89.4% of the total nitrogen (TN) was removed from AEFTW at a low S/N of 0.9 and 88.5% from HEFTW at a low C/N of 3.5 when the hydraulic retention time (HRT) was 1d in summer...
March 9, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28323624/conventional-or-natural-pharmacotherapy-and-the-prevalence-of-anxiety-and-depression-during-menopause
#8
Dorota Kopciuch, Anna Paczkowska, Tomasz Zaprutko, Michał Michalak, Elżbieta Nowakowska
Context • Psychoneurological symptoms are present in nearly all women in the perimenopausal period. Key elements of care in the period may include hormone replacement therapy (HRT). Alternatively, phytoestrogens, antidepressant pharmacotherapy, or a combination of hormonal and antidepressant therapies may be recommended. Objective • The study intended to verify whether women who are menopausal believe that a reduction in their symptoms of anxiety and depression depends on the type of pharmacotherapy used...
March 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/28321784/co-fermentation-of-cheese-whey-and-crude-glycerol-in-egsb-reactor-as-a-strategy-to-enhance-continuous-hydrogen-and-propionic-acid-production
#9
Helberth Júnnior Santos Lopes, Lucas Rodrigues Ramos, Edson Luiz Silva
This study evaluated the production of hydrogen and propionic acid in an expanded granular sludge bed (EGSB) reactor by co-fermentation of cheese whey (CW) and crude glycerol (CG). The reactor was operated at hydraulic retention time (HRT) of 8 h by changing the CW/CG ratio from 5:1 to 5:2, 5:3, 5:4, and 5:5. At the ratio of 5:5, HRT was reduced from 8 to 0.5 h. The maximum hydrogen yield of 0.120 mmol H2 g COD(-1) was observed at the CW/CG ratio of 5:1. Increasing the CG concentration repressed hydrogen production in favor of propionic acid, with a maximum yield of 6...
March 20, 2017: Applied Biochemistry and Biotechnology
https://www.readbyqxmd.com/read/28319759/removal-of-hydrogen-sulfide-generated-during-anaerobic-treatment-of-sulfate-laden-wastewater-using-biochar-evaluation-of-efficiency-and-mechanisms
#10
Jarupat Kanjanarong, Balendu S Giri, Deb P Jaisi, Fernanda R Oliveira, Piyarat Boonsawang, Sumate Chaiprapat, R S Singh, Avula Balakrishna, Samir Kumar Khanal
Removal of hydrogen sulfide (H2S) from biogas was investigated in a biochar column integrated with a bench-scale continuous-stirred tank reactor (CSTR) treating sulfate-laden wastewater. Synthetic wastewater containing sulfate concentrations of 200-2000mg SO4(2-)/L was used as substrate, and the CSTR was operated at an organic loading rate of 1.5g chemical oxygen demand (COD)/L·day and a hydraulic retention time (HRT) of 20days. The biochar was able to remove about 98.0 (±1.2)% of H2S for the ranges of concentrations from 105-1020ppmv, especially at high moisture content (80-85%)...
March 4, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28317451/inclusion-of-saccharina-latissima-in-conventional-anaerobic-digestion-systems
#11
F Ometto, A Berg, A Björn, L Safaric, B H Svensson, A Karlsson, J Ejlertsson
Loading macroalgae into existing anaerobic digestion (AD) plants allows us to overcome challenges such as low digestion efficiencies, trace elements limitation, excessive salinity levels and accumulation of volatile fatty acids (VFAs), observed while digesting algae as a single substrate. In this work, the co-digestion of the brown macroalgae Saccharina latissima with mixed municipal wastewater sludge (WWS) was investigated in mesophilic and thermophilic conditions. The hydraulic retention time (HRT) and the organic loading rate (OLR) were fixed at 19 days and 2...
March 18, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28315058/improving-egsb-reactor-performance-for-simultaneous-bioenergy-and-organic-acid-production-from-cheese-whey-via-continuous-biological-h2-production
#12
Lucas Rodrigues Ramos, Edson Luiz Silva
OBJECTIVES: To evaluate the influence of hydraulic retention time (HRT) and cheese whey (CW) substrate concentration (15 and 25 g lactose l(-1)) on the performance of EGSB reactors (R15 and R25, respectively) for H2 production. RESULTS: A decrease in the HRT from 8 to 4 h favored the H2 yield and H2 production rate (HPR) in R15, with maximum values of 0.86 ± 0.11 mmol H2 g COD(-1) and 0.23 ± 0.024 l H2 h(-1) l(-1), respectively. H2 production in R25 was also favored at a HRT of 4 h, with maximum yield and HPR values of 0...
March 17, 2017: Biotechnology Letters
https://www.readbyqxmd.com/read/28303746/novel-design-and-optimisation-of-a-nitritation-anammox-setup-for-ammonium-removal-from-filtrate-of-digested-sludge
#13
Yury Nikolaev, Anna Kallistova, Marina Kevbrina, Alexander Dorofeev, Anton Agarev, Andrey Mardanov, Nikolay Ravin, Michail Kozlov, Nikolay Pimenov
Although anammox process is extensively applied to the treatment of high-strength ammonium wastewater, new technical solutions overcoming the operational difficulties remain an important task. In this study, an innovative design of anammox-based setup was employed to improve sludge settling under high ammonium load (up to 1000 mg NH4-N/l/d). The setup treated the filtrate of digested sludge and included a completely mixed constant flow bioreactor with suspended and immobilised activated sludge. Suspended sludge was recycled via a settler...
March 17, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28300373/sum-signal-dosimetry-a-new-approach-for-high-dose-quality-assurance-with-gafchromic-ebt3
#14
Davide Cusumano, Maria Luisa Fumagalli, Francesco Ghielmetti, Linda Rossi, Giuliano Grossi, Raffaella Lanzarotti, Laura Fariselli, Elena De Martin
Gafchromic EBT3 film dosimetry in radiosurgery (RS) and hypofractionated radiotherapy (HRT) is complicated by the limited film accuracy at high fractional doses. The aim of this study is to develop and evaluate sum signal (SS) film dosimetry to increase dose resolution at high fractional doses, thus allowing for use of EBT3 for dose distribution verification of RS/HRT treatments. To characterize EBT3 dose-response, a calibration was performed in the dose range 0.44-26.43 Gy. Red (RC) and green (GC) channel net optical densities were linearly added to produce the SS...
March 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28294471/ultra-brief-behavioral-skills-trainings-for-blood-injection-injury-phobia
#15
Alicia E Meuret, Erica Simon, Lavanya Bhaskara, Thomas Ritz
BACKGROUND: Blood injection injury (BII) phobia is common, with debilitating consequences to the health and well being of many of its sufferers. BII phobia presents with a unique fear response that can involve drops in blood pressure and ultimately fainting. The aim of this study was to provide proof of concept for a line of brief, easy to implement, video-based interventions for reducing phobic avoidance and fears in BII sufferers. One of the interventions was a novel Hypoventilation Respiratory Training (HRT) aimed at reducing the exaggerated ventilation response (hyperventilation) seen in BII phobia...
March 15, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28293621/development-of-the-physical-activity-and-your-nutrition-for-cancer-pync-smartphone-app-for-preventing-breast-cancer-in-women
#16
Steven S Coughlin, Gina M Besenyi, Deborah Bowen, Gianluca De Leo
BACKGROUND: In the U.S., breast cancer accounts for more cancer deaths in women than any site other than lung cancer. Based upon attributable risks, about 30-35% of breast cancers could potentially be prevented by addressing obesity, physical inactivity, increased alcohol consumption, and carcinogenic exposures such as hormone replacement therapy (HRT). We need methods of reducing women's risks of this disease that are attractive and easy to use, widely accessible to diverse women, and able to be easily amended to account for new research...
2017: MHealth
https://www.readbyqxmd.com/read/28289899/role-of-bmi-and-hormone-therapy-in-melanoma-risk-a-case-control-study
#17
Vincenzo De Giorgi, Alessia Gori, Imma Savarese, Antonietta D'Errico, Federica Scarfì, Federica Papi, Vincenza Maio, Piero Covarelli, Daniela Massi, Sara Gandini
BACKGROUND: Currently, the association between body mass index (BMI) and hormone therapies and Cutaneous Melanoma (CM) development is strongly debated. This study was carried out to assess the association between BMI, hormone therapies, and CM risk. METHODS: The present study is a hospital-based case-control study with 605 consecutive CM patients and 592 controls treated for non-neoplastic conditions at the Department of Dermatology in Florence. The associations of melanoma risk with BMI and hormone therapies were assessed performing unconditional logistic regression to estimate odds ratios (OR) and their 95% confidence intervals, adjusting for potential confounders...
March 13, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28288659/a-clinical-model-for-identifying-the-short-term-risk-of-breast-cancer
#18
Mikael Eriksson, Kamila Czene, Yudi Pawitan, Karin Leifland, Hatef Darabi, Per Hall
BACKGROUND: Most mammography screening programs are not individualized. To efficiently screen for breast cancer, the individual risk of the disease should be determined. We describe a model that could be used at most mammography screening units without adding substantial cost. METHODS: The study was based on the Karma cohort, which included 70,877 participants. Mammograms were collected up to 3 years following the baseline mammogram. A prediction protocol was developed using mammographic density, computer-aided detection of microcalcifications and masses, use of hormone replacement therapy (HRT), family history of breast cancer, menopausal status, age, and body mass index...
March 14, 2017: Breast Cancer Research: BCR
https://www.readbyqxmd.com/read/28288312/evaluation-of-thermally-modified-calcium-rich-attapulgite-as-a-low-cost-substrate-for-rapid-phosphorus-removal-in-constructed-wetlands
#19
Hongbin Yin, Xiaowei Yan, Xiaohong Gu
The cost-effective and geographically available substrates are vital for the design of constructed wetlands (CWs), especially the saturated subsurface flow CWs, which are deemed as an efficient way to remove the inlet-lake phosphorus concentrations. In this study, phosphorus removal of thermally-treated calcium-rich attapulgite (TCAP) with varied particle sizes (0.2-0.5 mm, 0.5-1 mm and 1-2 mm) was assessed using batch and long-term column experiments to evaluate its feasibility as a CWs substrate. The phosphorus-bound mechanism in TCAP was identified in various initial phosphorus concentrations...
March 6, 2017: Water Research
https://www.readbyqxmd.com/read/28285224/energy-savings-and-higher-volumetric-loading-rate-achieved-in-the-conventional-anoxic-oxic-process-for-sewage-treatment-by-enhancing-biomass-retention-in-the-secondary-clarifier
#20
Xueyu Zhang, Fengyuan Liu, Shaokui Zheng
This is the first study to achieve a short HRT (∼2h for the A/O reactor), high MLSS (∼10gL(-1)), and high volumetric loading (∼3.7kg CODm(-3)d(-1) and ∼0.6kg NH4-Nm(-3)d(-1)) in the A/O process for sewage treatment by enhancing biomass retention in the secondary clarifier (∼4h settling time), which we refer to as the high-performance A/O process (HP-A/O) in this paper. Over 258days of continuous operation, with a decrease in HRT from 12 to 2h, remarkable COD (95±3%), NH4(+)-N (98±2%), TN (79±5%), and TP (74±10%) removals were stably achieved, while the air requirement significantly decreased by 22%...
March 1, 2017: Bioresource Technology
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