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https://www.readbyqxmd.com/read/29778041/the-efficacy-of-vitamin-d-in-multiple-sclerosis-a-meta-analysis
#1
REVIEW
Chao Zheng, Liang He, Lingling Liu, Jie Zhu, Tao Jin
BACKGROUND: Multiple sclerosis (MS) is a chronic inflammatory demyelination disorder in the central nervous system (CNS) leading to a high level of neurological disability. The pathogenesis of MS remains largely unknown, which explains the lack of significant efficacy of therapy in MS. Vitamin D deficiency is widely considered to be an environmental risk factor for MS. Many studies investigating the therapeutic effects of vitamin D on MS have been applied. The objective of this systematic review and meta-analysis was to evaluate the effectiveness of vitamin D in MS patients...
May 12, 2018: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29777965/what-do-we-know-about-sibling-attended-birth-an-integrative-literature-review
#2
REVIEW
Nora L Naber, Suzanne Miller, Sally A Baddock
OBJECTIVE: to consolidate existing research in the field of sibling attended birth (SAB) into a body of knowledge to inform decision-making processes and guide midwifery practice throughout the sibling attended birth experience. DESIGN: An integrative literature review. DATA SOURCES: CINAHL Complete, Cochrane Library, PubMed, Index New Zealand, Australia/New Zealand Reference Centre, grey literature databases REVIEW METHODS: An extensive search of five electronic databases as well as 17 grey literature databases was conducted...
May 8, 2018: Midwifery
https://www.readbyqxmd.com/read/29777956/how-do-gender-relations-affect-the-working-lives-of-close-to-community-health-service-providers-empirical-research-a-review-and-conceptual-framework
#3
Rosalind Steege, Miriam Taegtmeyer, Rosalind McCollum, Kate Hawkins, Hermen Ormel, Maryse Kok, Sabina Rashid, Lilian Otiso, Mohsin Sidat, Kingsley Chikaphupha, Daniel Gemechu Datiko, Rukhsana Ahmed, Rachel Tolhurst, Woedem Gomez, Sally Theobald
Close-to-community (CTC) providers have been identified as a key cadre to progress universal health coverage and address inequities in health service provision due to their embedded position within communities. CTC providers both work within, and are subject to, the gender norms at community level but may also have the potential to alter them. This paper synthesises current evidence on gender and CTC providers and the services they deliver. This study uses a two-stage exploratory approach drawing upon qualitative research from the six countries (Bangladesh, Indonesia, Ethiopia, Kenya, Malawi, Mozambique) that were part of the REACHOUT consortium...
May 5, 2018: Social Science & Medicine
https://www.readbyqxmd.com/read/29777927/patient-related-determinants-of-antibiotic-use-a-systematic-review
#4
REVIEW
V Zanichelli, G Tebano, I C Gyssens, V Vlahović-Palčevski, A A Monnier, M Stanic Benic, S Harbarth, M Hulscher, C Pulcini, B D Huttner
OBJECTIVES: We aimed to assess patient-related determinants potentially influencing antibiotic use. METHODS: Studies published in MEDLINE until 30/09/2015 were searched. We included: (1) qualitative studies describing patients' self-reported determinants of antibiotic use; (2) quantitative studies on either self-reported or objectively assessed determinants associated with antibiotic use. Whenever possible, reported determinants were categorized as "barriers" or "facilitators" of responsible antibiotic use...
May 16, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29777926/epidemiology-of-acute-febrile-illness-in-latin-america
#5
REVIEW
José Moreira, Clarisse S Bressan, Patricia Brasil, Andre M Siqueira
BACKGROUND: The causes of acute febrile illness (AFI) in Latin America (LA) are diverse and its complexity increase as the proportion of fever due to malaria decreases as control and new pathogens emerge in the region. In this context, it is important to shed light over the gaps on the epidemiological characteristics and the geographic range for many AFI aetiologies. AIMS: To review studies on community-acquired fever etiology other than malaria in LA, and to highlight knowledge gaps and challenges needing further investigation...
May 16, 2018: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29777909/lncrnas-as-potential-molecular-biomarkers-for-the-clinicopathology-and-prognosis-of-glioma-a-systematic-review-and-meta-analysis
#6
REVIEW
Qian Zhou, Jing Liu, Jing Quan, Wenlan Liu, Hui Tan, Weiping Li
BACKGROUND: An increasing number of studies have shown that long noncoding RNAs (lncRNAs) play important roles in the development of glioma. However, a systematic review and meta-analysis to evaluate the clinical value of lncRNA expression in glioma patients is lacking. We performed this study to assess the relationship between the expression of various lncRNAs and the clinicopathological features, diagnosis and prognosis of glioma. MATERIALS AND METHODS: Eligible studies were identified through a comprehensive literature search...
May 16, 2018: Gene
https://www.readbyqxmd.com/read/29777881/single-incision-laparoscopic-versus-conventional-laparoscopic-right-colectomy-a-systematic-review-and-meta-analysis
#7
REVIEW
Boye Dong, Zuyang Luo, Jiabao Lu, Yang Yang, Yixian Song, Jie Cao, Wanglin Li
BACKGROUND: Single-incision laparoscopic surgery has gained widespread attention because of its potential benefits such as less skin incision and faster recovery. Up to now, only one meta-analysis (performed in 2013; including 9 studies, a total of 585 cases) compared single-incision laparoscopic right colectomy (SILRC) with conventional laparoscopic right colectomy (CLRC). An updated meta-analysis was undertaken to explore more convinced comparative findings between SILRC and CLRC. MATERIALS AND METHODS: The search for studies that compared SILRC with CLRC was done on PubMed, Embase, Web of Science, and the Cochrane Library...
May 16, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29777868/comparative-efficacy-and-safety-of-different-antiviral-agents-for-cytomegalovirus-prophylaxis-in-allogeneic-hematopoietic-cell-transplantation-a-systematic-review-and-meta-analysis
#8
Nico Gagelmann, Per Ljungman, Jan Styczynski, Nicolaus Kröger
Over the past 25 years, several randomized controlled trials have investigated the efficacy of different antiviral agents for cytomegalovirus (CMV) prophylaxis in allogeneic hematopoietic-cell transplantation. We performed a systematic literature review, conventional meta-analysis and network meta-analysis using a random-effects model and risk ratios (RR) with corresponding 95% confidence intervals (CI) as effect estimates. Fifteen randomized controlled trials were identified, including seven different antiviral agents: acyclovir, ganciclovir, maribavir, brincidofovir, letermovir, valacyclovir, and vaccine...
May 16, 2018: Biology of Blood and Marrow Transplantation
https://www.readbyqxmd.com/read/29777863/comparison-of-histological-and-morphometrical-changes-underlying-subchondral-bone-abnormalities-in-inflammatory-and-degenerative-musculoskeletal-disorders-a-systematic-review
#9
REVIEW
M Loef, S van Beest, F P B Kroon, J L Bloem, O M Dekkers, M Reijnierse, J W Schoones, M Kloppenburg
OBJECTIVE: Subchondral bone abnormalities (SBAs) on magnetic resonance imaging (MRI) are observed frequently and associated with disease course in various musculoskeletal disorders. This review aims to map the existing knowledge of their underlying histological features, and to identify needs for future research. DESIGN: We conducted a systematic review following PRISMA guidelines until September 2017, including all studies correlating histological features to on MRI defined SBAs in patients with osteoarthritis (OA), rheumatoid arthritis (RA), spondyloarthritis (SpA) and degenerative disc disease (DDD)...
May 16, 2018: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29777798/predominance-of-high-or-unclear-risk-of-bias-assessments-in-diagnostic-accuracy-studies-included-in-cochrane-reviews
#10
Nicola Di Girolamo, Alexandra Winter, Reint Meursinge Reynders
OBJECTIVES: The validity of outcomes of systematic reviews is highly dependent on the extent of bias in the included primary studies. This study reports the risk of bias of primary studies included in systematic reviews of diagnostic accuracy. STUDY DESIGN AND SETTING: All systematic reviews of diagnostic accuracy studies published in the Cochrane database in 2015 and 2016 that used the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) risk of bias (ROB) tool, and reported results with the ROB figure were eligible...
May 16, 2018: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/29777729/pharmacogenetic-tests-to-guide-drug-treatment-in-depression-comparison-of-the-available-testing-kits-and-clinical-trials
#11
REVIEW
Chiara Fabbri, Joseph Zohar, Alessandro Serretti
The empirical approach to drug choice and dosing in depression often results into inadequate response and side effects. Pharmacogenetic (PGx) testing appears a promising way to implement personalized treatments. A systematic review was performed to identify available PGx tests, compare the genes they include with clinical guidelines and drug labels, and assess the quality of published clinical studies. ~40 commercial PGx tests are available and potential benefits were estimated for nine of them by clinical studies...
May 16, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29777531/the-directional-and-non-directional-associations-of-periodontitis-with-chronic-kidney-disease-a-systematic-review-and-meta-analysis-of-observational-studies
#12
REVIEW
D Zhao, A T Khawaja, L Jin, K-Y Li, M Tonetti, G Pelekos
This systematic review aimed to assess the current evidence on the directional and non-directional associations of periodontitis with chronic kidney disease (CKD). Electronic search for observational studies on the association of periodontitis with CKD was performed in MEDLINE, EMBASE, PubMed, Open GREY and Cochrane library up to June 5, 2017. Two reviewers conducted study selection, data collection and assessment of methodological quality using the original and modified Newcastle-Ottawa Scale. Cohort, case-control and cross-sectional studies were included, which clearly defined periodontitis and CKD or reported acceptable clinical parameters of these 2 diseases in adults...
May 18, 2018: Journal of Periodontal Research
https://www.readbyqxmd.com/read/29777471/the-association-between-emotional-and-behavioral-problems-in-children-with-autism-spectrum-disorder-and-psychological-distress-in-their-parents-a-systematic-review-and-meta-analysis
#13
Isabel Yorke, Pippa White, Amelia Weston, Monica Rafla, Tony Charman, Emily Simonoff
This review (Prospero Registration Number: CRD42017057915) aimed to systematically identify and summarize existing research on the relationship between additional emotional and behavioral problems (EBP) in children with autism, and parenting stress (PS) and mental health problems (MHP) in their parents. Sixty-seven studies met criteria for inclusion in the review, 61 of which were included in the meta-analysis. Pooled correlation coefficients were in the low to moderate range ([Formula: see text]). Some evidence for moderation by measurement characteristics was found...
May 18, 2018: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29777464/the-key-features-approach-to-assess-clinical-decisions-validity-evidence-to-date
#14
REVIEW
G Bordage, G Page
The key-features (KFs) approach to assessment was initially proposed during the First Cambridge Conference on Medical Education in 1984 as a more efficient and effective means of assessing clinical decision-making skills. Over three decades later, we conducted a comprehensive, systematic review of the validity evidence gathered since then. The evidence was compiled according to the Standards for Educational and Psychological Testing's five sources of validity evidence, namely, Content, Response process, Internal structure, Relations to other variables, and Consequences, to which we added two other types related to Cost-feasibility and Acceptability...
May 17, 2018: Advances in Health Sciences Education: Theory and Practice
https://www.readbyqxmd.com/read/29777452/revision-of-surgical-margin-under-frozen-section-to-achieve-r0-status-on-survival-in-patients-with-pancreatic-cancer
#15
Zi Yin, Yu Zhou, Baohua Hou, Tingting Ma, Min Yu, Chuanzhao Zhang, Xin Lu, Zhixiang Jian
OBJECTIVE: The aim is to investigate whether additional resection based on intraoperative frozen section (FS) to a secondary R0(s) status are associated with different long-term survivals in pancreatic cancer patients, comparing to those with R1 or primary R0(p) status. METHODS: A systematic literature search (PubMed, Embase, Science Citation Index, Springer-Link, and Cochrane Central Register of Controlled Trials) was performed to identify all studies published up to June 2017...
May 18, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29777357/optimizing-the-image-of-fluorescence-cholangiography-using-icg-a-systematic-review-and-ex-vivo-experiments
#16
Jacqueline van den Bos, Fokko P Wieringa, Nicole D Bouvy, Laurents P S Stassen
BACKGROUND: Though often only briefly described in the literature, there are clearly factors that have an influence on the fluorescence intensity, and thereby the usefulness of the technique. This article aims to provide an overview of the factors influencing the fluorescence intensity of fluorescence imaging with Indocyanine green, primarily focussed on NIRF guided cholangiography. METHODS: A systematic search was conducted to gain an overview of currently used methods in NIRF imaging in laparoscopic cholecystectomies...
May 18, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29777352/forward-viewing-endoscope-for-ercp-in-patients-with-billroth-ii-gastrectomy-a-systematic-review-and-meta-analysis
#17
Tae Young Park, Chang Seok Bang, Sang Hyeon Choi, Young Joo Yang, Suk Pyo Shin, Ki Tae Suk, Gwang Ho Baik, Dong Joon Kim, Jai Hoon Yoon
BACKGROUND: The forward-viewing endoscope has been increasingly used to perform endoscopic retrograde cholangiopancreatography (ERCP) in patients who underwent Billroth II gastrectomy. This study intended to assess efficacy and safety of the forward-viewing endoscope for ERCP in Billroth II gastrectomy patients compared with conventional side-viewing endoscope using a systematic review and meta-analysis. METHODS: A systematic review was conducted for studies that evaluated the outcomes of ERCP for patients with Billroth II gastrectomy...
May 17, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29777351/development-of-a-patient-reported-outcome-measure-of-recovery-after-abdominal-surgery-a-hypothesized-conceptual-framework
#18
Roshni Alam, Sabrina M Figueiredo, Saba Balvardi, Bénédicte Nauche, Tara Landry, Lawrence Lee, Nancy E Mayo, Liane S Feldman, Julio F Fiore
BACKGROUND: We initiated a research program to develop a novel patient-reported outcome measure (PROM) to assess postoperative recovery from the perspective of abdominal surgery patients. In light of FDA recommendations, the first stage of our program aimed to, based on previous literature and expert input, develop a hypothesized conceptual framework portraying the health domains that are potentially relevant to the process of recovery after abdominal surgery. METHODS: This study was conducted in three phases: (1) systematic review to identify PROMs with measurement properties appraised in the context of recovery after abdominal surgery, (2) content analysis to categorize the health domains covered by the PROMs according to the ICF, and (3) two-round Delphi study to gain expert input regarding which of these health domains are relevant to the process of recovery...
May 17, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29777347/intrauterine-hpv-transmission-a-systematic-review-of-the-literature
#19
REVIEW
Andreas Zouridis, Theodoros Kalampokas, Konstantinos Panoulis, Nicolaos Salakos, Efthimios Deligeoroglou
PURPOSE: To evaluate the percentage of intrauterine vertical human papillomavirus (HPV) transmission among HPV-positive mothers and the relative risk of intrauterine vertical HPV transmission between cesarean and vaginal delivery among HPV-positive women. METHODS: This systematic review was made according to the PRISMA statement. We searched PubMed and Scopus and the final articles were selected by two reviewers. Data from the selected articles were plotted, and the pooled percentage of antenatal vertical HPV transmission among HPV-positive mothers as well as the pooled relative risk of antenatal vertical HPV transmission between cesarean and vaginal delivery among HPV-positive women were calculated...
May 18, 2018: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/29777328/a-systematic-review-on-the-off-label-use-of-montelukast-in-atopic-dermatitis-treatment
#20
Weng Khong Chin, Shaun Wen Huey Lee
Background Atopic dermatitis (AD) is the most common form of eczema. As leukotriene mediators are involved in the inflammatory phase of atopic dermatitis, montelukast has been suggested as a possible therapy. Aim of the review To evaluate the safety and efficacy of montelukast off-label use for the treatment atopic dermatitis. Method A search was performed from database inception until March 2018 in six electronic databases for randomized-controlled-trials examining the use of montelukast for AD. Results Among 301 articles screened, 11 studies met the inclusion criteria and were included in the review...
May 18, 2018: International Journal of Clinical Pharmacy
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