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Glycolic Peel

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https://www.readbyqxmd.com/read/29164826/comparative-study-of-buffered-50-glycolic-acid-ph-3-0-0-5-salicylic-acid-solution-vs-jessner-s-solution-in-patients-with-acne-vulgaris
#1
Jeong In Jae, Hyun Dong Ju, Kim Dong Hyun, Moon Soo Yoon, Hee Jung Lee
BACKGROUND: Superficial chemical peels are frequently used in acne vulgaris treatment. Although glycolic acid (GA) has been widely used in clinical practice, its pH ranges from 0.08-2.75 and thus should be neutralized after application to avoid burns. OBJECTIVE: To evaluate treatment efficacy and safety of chemical peeling using buffered 50% GA (pH 3.0) + 0.5% salicylic acid (SA) solution that does not need to be neutralized in the treatment of acne vulgaris compared to the conventional peeling using Jessner's solution...
November 21, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29152631/mask-free-fabrication-of-a-versatile-microwell-chip-for-multidimensional-cellular-analysis-and-drug-screening
#2
Wenguang Yang, Haibo Yu, Gongxin Li, Fanan Wei, Yuechao Wang, Lianqing Liu
Cells are frequently studied because they are basic structural, functional, and biological units of living organisms. Extracting features from cellular behaviors can facilitate decision making in medical diagnoses and represents an important aspect in the development of biomedical engineering. Previous studies have just focused on either the individual cell or cell clusters separately, which leads to a great lack of information. Microwell technologies could address the challenges of in vitro cellular studies, from individual cell studies to 3D functional assays, by providing more information from smaller sample volumes and enabling the incorporation of low-cost high-throughput assays in the drug discovery process...
November 20, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/29142390/a-comprehensive-study-on-fast-dispersible-and-slow-releasing-characteristic-of-orange-peel-pectin-in-relation-to-established-synthetic-polymer
#3
Pranati Srivastava, Mahendra Singh, Shilpi Bhargava
Introduction: In the present work, the method to extract, isolate, and characterize orange peel pectin using soxhlation, and thereafter, the use of this polymer-polymer in the formulation of fast dispersable and slow-releasing tablet has been studied. Thereafter, the evaluation and comparison of fast dispersible/slow-releasing tablets using orange peel pectin versus prepared using sodium starch glycolate (SSG) were carried out. Materials and Methods: In the present investigation, extraction methodology was employed for isolation of pectin from orange peels...
October 2017: Pharmacognosy Magazine
https://www.readbyqxmd.com/read/29072375/efficacy-of-microneedling-with-70-glycolic-acid-peel-vs-microneedling-alone-in-treatment-of-atrophic-acne-scars-a-randomized-controlled-trial
#4
Shiwangi Rana, Vibhu Mendiratta, Ram Chander
BACKGROUND: Microneedling with dermaroller and glycolic acid peels is commonly used for treatment of acne scars. OBJECTIVE: To compare efficacy of microneedling alone versus combination of microneedling with serial 70% glycolic acid peel in management of atrophic acne scars. METHODS & MATERIALS: Sixty patients with atrophic acne scars were randomized into group 1 receiving microneedling at 0, 6, and 12 weeks and group 2 receiving microneedling at 0, 6, and 12 weeks along with 70% glycolic acid peel at 3, 9, and 15 weeks...
October 26, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/29026207/citrus-peel-essential-oil-nanoformulations-to-control-the-tomato-borer-tuta-absoluta-chemical-properties-and-biological-activity
#5
Orlando Campolo, Asma Cherif, Michele Ricupero, Gaetano Siscaro, Kaouthar Grissa-Lebdi, Agatino Russo, Lorena M Cucci, Patrizia Di Pietro, Cristina Satriano, Nicolas Desneux, Antonio Biondi, Lucia Zappalà, Vincenzo Palmeri
The repeated use of conventional synthetic pesticides in crop protection leads to resistance development by pests along with a negative impact on the environment, particularly non-target arthropods. Plant-derived active compounds, such as essential oils (EOs), play a key role in sustainably controlling pests. The lethal and sublethal activity of citrus peel EOs as emulsions and included in polyethylene glycol (PEG) nanoparticles (EO-NPs) was determined against the invasive tomato pest Tuta absoluta. Their effects on the plants were also assessed...
October 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28819900/effect-of-polyethylene-glycol-on-the-nio-photocathode
#6
Shengjun Li, Zeng Chen, Wenping Kong, Xiyang Jia, Junhao Cai, Shaokang Dong
In this study, a uniform nanoporous NiO film, with a thickness of up to 2.6 μm, was prepared using polyethylene glycol (PEG). The addition of PEG significantly decreased the cracks in the NiO film and prevented the peeling of the NiO film from a fluorine-doped tin oxide substrate. The NiO cathode was prepared using CdSeS quantum dots (QDs) as the sensitizer, with an optimized photoelectric conversion of 0.80%. The optimized QD-sensitized NiO films were first assembled with the TiO2 anode to prepared QD-sensitized p-n-type tandem solar cells...
August 17, 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28657376/glycolic-acid-peel-in-disseminated-facial-verrucae
#7
Seema Rani, Preeti Sharma
Facial warts are a common cause of cosmetic concern and also affect the self-esteem of the affected patients. These are benign skin papillomas caused by human papillomavirus infections. Warts affecting the face are mainly due to HPV-3 and HPV-10. Destructive and caustic agents used for the treatment can produce scarring at these site, hence should be used with care. Earlier, glycolic acid alone as well as in combination with salicylic acid in gel base formulation have been used to treat facial recalcitrant wart with good results...
June 28, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28607861/a-deceptively-simple-solution-for-refractory-melasma-glycolic-acid-peels-and-hydroquinone-at-home
#8
Takanobu Mashiko, Aiko Oka, Ema Osawa, Isao Koshima
Although various treatment methods for melasma have developed, substantial improvement of the condition is sometimes difficult. We have experientially found that some of refractory melasma caused by daily friction can easily be treated by using a combination of a peeling agent (20% glycolic acid) and a depigmenting agent (5% hydroquinone) twice daily at home. And here, by performing skin biopsies, we revealed the pathological mechanism: hyperkeratosis caused by repeated physical stimulus, which prevents infiltration of topical therapeutic agents, was dramatically reduced by chemical peeling, resulting that the melanin pigments were effectively cleared by topical hydroquinone...
May 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28569570/efficacy-of-peeling-during-different-periods-of-the-menstrual-cycle-on-acne
#9
Emel Bulbul Baskan, Işıl Tilki Günay, Hayriye Saricaoglu
BACKGROUND AND DESIGN: The aim of this study was to investigate the efficacy of 50% glycolic acid peeling performed at different phases of menstruation on acne. MATERIALS AND METHODS: This study included 30 patients with mild-to-moderate acne. Those with regular menstrual cycles and no history or laboratory evidence of hormonal pathology, hirsutism were selected. Thirty patients were divided in three groups. The first group received peeling applications in the first 7 days of menstruation; the second group received the peel between 10 and 14 days; and the third group received the peel during the last 10 days of menstruation...
October 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28538881/efficacy-and-safety-of-superficial-chemical-peeling-in-treatment-of-active-acne-vulgaris
#10
REVIEW
Hassanain Al-Talib, Alyaa Al-Khateeb, Ayad Hameed, Chandrika Murugaiah
Acne vulgaris is an extremely common condition affecting the pilosebaceous unit of the skin and characterized by presence of comedones, papules, pustules, nodules, cysts, which might result in permanent scars. Acne vulgaris commonly involve adolescents and young age groups. Active acne vulgaris is usually associated with several complications like hyper or hypopigmentation, scar formation and skin disfigurement. Previous studies have targeted the efficiency and safety of local and systemic agents in the treatment of active acne vulgaris...
March 2017: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28532898/toughening-of-fibrous-scaffolds-by-mobile-mineral-deposits
#11
Justin Lipner, John J Boyle, Younan Xia, Victor Birman, Guy M Genin, Stavros Thomopoulos
Partially mineralized fibrous tissue situated between tendon and bone is believed to be tougher than either tendon or bone, possibly serving as a compliant, energy absorptive, protective barrier between the two. This tissue does not reform following surgical repair (e.g., rotator cuff tendon-to-bone re-attachment) and might be a factor in the poor outcomes following such surgeries. Towards our long-term goal of tissue engineered solutions to functional tendon-to-bone re-attachment, we tested the hypotheses that partially mineralized fibrous matrices can derive toughness from mobility of mineral along their fibers, and that in such cases toughness is maximized at levels of mineralization sufficiently low to allow substantial mobility...
August 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28529418/intra-individual-right-left-comparative-study-of-medium-depth-peels-in-superficial-nail-abnormalities
#12
Deepashree Daulatabad, Soni Nanda, Chander Grover
BACKGROUND: Superficial nail abnormalities include conditions which produce nail surface changes such as trachyonychia, pitting and ridging. Mostly, this is a neglected area due to the dearth of treatment options. Glycolic acid peeling has been reported to be effective in such cases. AIM: This study aims to assess the safety and efficacy of medium depth peels (70% glycolic acid versus phenol combination peel [8% phenol with 15% trichloroacetic acid]) in patients with superficial nail abnormalities...
January 2017: Journal of Cutaneous and Aesthetic Surgery
https://www.readbyqxmd.com/read/28492048/a-review-of-the-safety-of-cosmetic-procedures-during-pregnancy-and-lactation
#13
REVIEW
M K Trivedi, G Kroumpouzos, J E Murase
The safety of cosmetic procedures in patients who are pregnant and/or lactating is a complex clinical question surrounded by uncertainty. Our objective is to consolidate data on the safety of commonly requested cosmetic procedures during pregnancy and lactation after a systematic review of the current literature to guide evidence-based care in the future. A systematic search of the PubMed database was conducted for articles on cosmetic procedures during pregnancy and lactation. Due to a lack of controlled trials, case reports and series were considered...
March 2017: International Journal of Women's Dermatology
https://www.readbyqxmd.com/read/28371271/development-of-hybrid-scaffolds-with-natural-extracellular-matrix-deposited-within-synthetic-polymeric-fibers
#14
Ritu Goyal, Maria E Vega, Alexandra K Pastino, Shivani Singh, Murat Guvendiren, Joachim Kohn, N Sanjeeva Murthy, Jean E Schwarzbauer
A major challenge of tissue engineering is to generate materials that combine bioactivity with stability in a form that captures the robust nature of native tissues. Here we describe a procedure to fabricate a novel hybrid extracellular matrix (ECM)-synthetic scaffold biomaterial by cell-mediated deposition of ECM within an electrospun fiber mat. Synthetic polymer fiber mats were fabricated using poly(desamino tyrosyl-tyrosine carbonate) (PDTEC) co-spun with poly(ethylene glycol) (PEG) used as a sacrificial polymer...
August 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28299301/solution-of-azelaic-acid-20-resorcinol-10-and-phytic-acid-6-versus-glycolic-acid-50-peeling-agent-in-the-treatment-of-female-patients-with-facial-melasma
#15
Gita Faghihi, Azam Taheri, Zabihollah Shahmoradi, Mohammad Ali Nilforoushzadeh
BACKGROUND: Melasma, a common acquired disorder of hyperpigmentation, especially in women, is often resistant to therapy. This study was aimed to evaluate the efficacy and safety of azelaic acid, resorcinol and phytic acid solution in chemical peeling of melasma in comparison to 50% glycolic acid. MATERIALS AND METHODS: This clinical trial was performed, on 42 female patients with bilateral melasma. Severity of melasma was assessed by melasma area and severity index (MASI)...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28294225/enhanced-sealing-strength-of-a-hydrophobically-modified-alaska-pollock-gelatin-based-sealant
#16
Y Mizuno, R Mizuta, M Hashizume, T Taguchi
The aim of this study was the development of an innovative biocompatible sealant composed of Alaska pollock-derived gelatin partially modified with a dodecyl group (C12-ApGltn) and a poly(ethylene glycol)-based crosslinker, pentaerythritol poly(ethylene glycol) ether tetrasuccinimidyl glutarate. The burst strength of the developed sealants was measured using porcine aorta and rat lungs. The maximum burst strength of a C12-ApGltn-based sealant against the porcine aorta was 4-fold higher than that of an original ApGltn (Org-ApGltn)-based sealant...
May 2, 2017: Biomaterials Science
https://www.readbyqxmd.com/read/28274356/chemical-peels-in-active-acne-and-acne-scars
#17
Georgios Kontochristopoulos, Eftychia Platsidaki
Chemical peeling is a widely used procedure in the management of acne and acne scars. It causes controlled destruction of a part of or the entire epidermis, with or without the dermis, leading to exfoliation and removal of superficial lesions, followed by regeneration of new epidermal and dermal tissues. The most frequently used peeling agents are salicylic acid, glycolic acid, pyruvic acid, lactic acid, mandelic acid, Jessner solution, trichloroacetic acid, and phenol. The appropriate peel is chosen based on the patient's skin type, acne activity, and type of acne scars...
March 2017: Clinics in Dermatology
https://www.readbyqxmd.com/read/28210390/a-case-of-lichen-planus-pigmentosus-with-facial-dyspigmentation-responsive-to-combination-therapy-with-chemical-peels-and-topical-retinoids
#18
Marisa Wolff, Nina Sabzevari, Charles Gropper, Cindy Hoffman
Lichen planus pigmentosus is a photodistributed dyschromia of unknown etiology described clinically as hyperpigmented gray-blue or brown-black macules or patches in a photodistributed pattern. Although there has been some debate, lichen planus pigmentosus is considered by many to be a separate diagnostic entity from ashy dermatosis or erythema dyschromicum perstans, which shares similar characteristics. Various treatment strategies have been applied to help resolve or improve the appearance of lichen planus pigmentosus lesions; however, an optimal treatment method is yet to be elucidated...
November 2016: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28114204/treatment-of-postinflammatory-hyperpigmentation-with-a-combination-of-glycolic-acid-peels-and-a-topical-regimen-in-dark-skinned-patients-a-comparative-study
#19
RANDOMIZED CONTROLLED TRIAL
Rashmi Sarkar, Nisha V Parmar, Sheilly Kapoor
BACKGROUND: Facial postinflammatory hyperpigmentation (PIH) is challenging to manage in patients with skin of color because of the risk of subsequent treatment-related hyperpigmentation. OBJECTIVE: To evaluate the safety and efficacy of combining glycolic acid (GA) peels with a modified Kligman formula (MKF) containing hydroquinone 2%, tretinoin 0.05%, and hydrocortisone 1% for the treatment of facial PIH in Indian patients. METHODS: Thirty Indian patients (Fitzpatrick skin Types III-V) with facial PIH were randomly assigned to 2 groups of 15 each...
April 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28097306/universal-trichloroacetic-acid-peel-technique-for-light-and-dark-skin
#20
Nabil Fanous, Shadi Zari
Importance: Despite their great potential, medium and deep trichloroacetic acid peels are underused in light-skinned patients and are rarely used in darker-skinned patients because of the widespread fear of pigmentary complications and scarring. This concern has led many physicians to opt for the use of lighter types of peels (glycolic acid peel, Jessner peel, etc) and different lasers and intense light technologies. Trichloroacetic acid peels have been described in numerous publications...
May 1, 2017: JAMA Facial Plastic Surgery
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