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https://www.readbyqxmd.com/read/28923031/positive-mental-health-literacy-development-and-validation-of-a-measure-among-norwegian-adolescents
#1
Hanne Nissen Bjørnsen, Mary Elizabeth Bradley Eilertsen, Regine Ringdal, Geir Arild Espnes, Unni Karin Moksnes
BACKGROUND: Mental health literacy (MHL), or the knowledge and abilities necessary to benefit mental health, is a significant determinant of mental health and has the potential to benefit both individual and public mental health. MHL and its measures have traditionally focused on knowledge and beliefs about mental -ill-health rather than on mental health. No measures of MHL addressing knowledge of good or positive mental health have been identified. AIM: This study aimed to develop and validate an instrument measuring adolescents' knowledge of how to obtain and maintain good mental health and to evaluate the psychometric properties of the instrument...
September 18, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28921549/%C3%AE-flucs-brighter-photinus-pyralis-firefly-luciferases-identified-by-surveying-consecutive-single-amino-acid-deletion-mutations-in-a-thermostable-variant
#2
Lisa M Halliwell, Amit P Jathoul, Jack P Bate, Harley L Worthy, James C Anderson, Dafydd D Jones, James A H Murray
The bright bioluminescence catalysed by Photinus pyralis firefly luciferase (Fluc) enables a vast array of life science research such as bioimaging in live animals and sensitive in vitro diagnostics. The effectiveness of such applications is improved using engineered enzymes that to date have been constructed using amino acid substitutions. We describe ΔFlucs: consecutive single amino acid deletion mutants within 6 loop structures of the bright and thermostable x11 Fluc. Deletion mutations are a promising avenue to explore new sequence and functional space and isolate novel mutant phenotypes...
September 16, 2017: Biotechnology and Bioengineering
https://www.readbyqxmd.com/read/28919844/practical-nutritional-recovery-strategies-for-elite-soccer-players-when-limited-time-separates-repeated-matches
#3
REVIEW
Mayur Krachna Ranchordas, Joel T Dawson, Mark Russell
Specific guidelines that aim to facilitate the recovery of soccer players from the demands of training and a congested fixture schedule are lacking; especially in relation to evidence-based nutritional recommendations. The importance of repeated high level performance and injury avoidance while addressing the challenges of fixture scheduling, travel to away venues, and training commitments requires a strategic and practically feasible method of implementing specific nutritional strategies. Here we present evidence-based guidelines regarding nutritional recovery strategies within the context of soccer...
2017: Journal of the International Society of Sports Nutrition
https://www.readbyqxmd.com/read/28919794/parenteral-nutrition-including-an-omega-3-fatty-acid-containing-lipid-emulsion-for-intensive-care-patients-in-china-a-pharmacoeconomic-analysis
#4
Yufei Feng, Chao Li, Tian Zhang, Lorenzo Pradelli
BACKGROUND/OBJECTIVES: Parenteral nutrition (PN) incorporating omega-3 fatty-acid-enriched lipid emulsions has been shown to be cost effective in Western populations. A pharmacoeconomic evaluation was performed within the Chinese intensive care unit (ICU) setting. This assessed whether the additional acquisition cost of PN with omega-3 fatty-acid-enriched lipid emulsion (SMOFlipid) vs standard PN was offset by improved clinical outcomes that can reduce subsequent costs. MATERIALS AND METHODS: A pharmacoeconomic discrete event simulation model was developed, based on an update to efficacy data from a previous international meta-analysis, with China-specific clinical and economic input parameters...
2017: ClinicoEconomics and Outcomes Research: CEOR
https://www.readbyqxmd.com/read/28919371/perinatal-deficiency-in-dietary-omega-3-fatty-acids-potentiates-sucrose-reward-and-diet-induced-obesity-in-mice
#5
Stéphanie Auguste, Sandeep Sharma, Alexandre Fisette, Caroline Daneault, Christine Des Rosiers, Stephanie Fulton
Insufficient dietary intake of essential omega-3 polyunsaturated fatty acids (N-3), especially during critical stages of development, is well-associated with negative neurological and metabolic consequences. The increased availability and intake of foods rich in saturated fat coincides with reduced N-3 consumption, yet how N-3 dietary deficiency during perinatal development modulates motivation for palatable food and interacts with a high-fat diet to affect body weight and emotional states is not clear. Pregnant C57Bl6 mice and pups were subjected to diets either deficient or adequate (control) in N-3 until postnatal day 21...
September 14, 2017: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/28918747/omega-3-polyunsaturated-fatty-acids-eicosapentaenoic-acid-and-docosahexaenoic-acid-enhance-dexamethasone-sensitivity-in-multiple-myeloma-cells-by-the-p53-mir-34a-bcl-2-axis
#6
Xianping Dai, Mengshun Li, Feng Geng
Dexamethasone is widely used in multiple myeloma (MM) for its cytotoxic effects on lymphoid cells. However, many MM patients are resistant to dexamethasone, although some can benefit from dexamethasone treatment. In this study, we noted that ω-3 polyunsaturated fatty acids (PUFAs) enhanced the dexamethasone sensitivity of MM cells by inducing cell apoptosis. q-PCR analysis revealed that miR-34a could be significantly induced by PUFAs in U266 and primary MM cells. Transfection with miR-34a antagonist or miR-34a agomir could restore or suppress the dexamethasone sensitivity in U266 cells...
July 2017: Biochemistry. Biokhimii︠a︡
https://www.readbyqxmd.com/read/28918314/empirical-research-evaluating-the-effects-of-non-traditional-approaches-to-enhancing-sleep-in-typical-and-clinical-children-and%C3%A2-young-people
#7
REVIEW
Karyn G France, Laurie K McLay, Jolene E Hunter, Madeline L S France
This paper examines the effects of non-traditional (non-behavioural and non-prescription pharmaceutical) approaches to sleep in children and young people (0-18 y). A systematic search identified 79 studies that met inclusion criteria. Seventeen percent of the studies were rated as having a conclusive level of evidence, forty-two percent with preponderant evidence and forty-one percent with only suggestive evidence. There were promising indications, with certain populations only, for aromatherapy, ketogenic diets, an elimination diet (few foods diet), elimination of cow's milk, avoidance of caffeine, tryptophan with adenosine and uridine, omega-3 and omega-6, valerian, music, osteopathic manipulation and white noise...
July 29, 2017: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/28917083/effects-of-single-or-combined-administration-of-salmon-calcitonin-and-omega-3-fatty-acids-versus-diclofenac-sodium-in-sodium-monoiodoacetate-induced-knee-osteoarthritis-in-male-wistar-rats
#8
Wale J Adeyemi, Luqman A Olayaki
BACKGROUND: There is a continuous search for a better therapy in osteoarthritis (OA) management. Therefore, this study investigated the effects of salmon calcitonin (Sct) and/or omega-3 fatty acids (N-3) relative to diclofenac sodium (DF) in induced knee osteoarthritic male Wistar rats. METHODS: The 40 rats that were used in this study were divided into 8 groups (n=5 rats), viz: Normal control; OA control; OA+N-3; OA+Low dose of Sct (Sct.Lw); OA+High dose of Sct (Sct...
September 16, 2017: Journal of Basic and Clinical Physiology and Pharmacology
https://www.readbyqxmd.com/read/28912361/impact-of-sleep-restriction-on-local-immune-response-and-skin-barrier-restoration-with-and-without-multi-nutrient-nutrition-intervention
#9
Tracey J Smith, Marques A Wilson, J Philip Karl, Jeb Orr, Carl D Smith, Adam D Cooper, Kristin J Heaton, Andrew J Young, Scott J Montain
Systemic immune function is impaired by sleep restriction. However, the impact of sleep restriction on local immune responses, and to what extent any impairment can be mitigated by nutritional supplementation is unknown. We assessed the effect of 72-h sleep restriction (2-h nightly sleep) on local immune function and skin barrier restoration of an experimental wound, and determined the influence of habitual protein intake (1.5 g·kg(-1)·d(-1)) supplemented with arginine, glutamine, zinc sulfate, vitamin C, vitamin D3 and omega-3 fatty acids compared to lower protein intake (0...
September 14, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28912100/influence-of-omega-3-fatty-acids-on-bovine-luteal-cell-plasma-membrane-dynamics
#10
Michele R Plewes, Patrick D Burns, Richard M Hyslop, B George Barisas
Fish oil is a rich source of omega-3 fatty acids which disrupt lipid microdomain structure and affect mobility of the prostaglandin F2α (FP) receptor in bovine luteal cells. The objectives of this study were to determine the effects of individual omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on 1) membrane fatty acid composition, 2) lipid microdomain structure, and 3) lateral mobility of the FP receptor in bovine luteal cells. Ovaries were collected from a local abattoir (n=5/experiment)...
September 11, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28910189/associations-among-omega-3-fatty-acid-status-anxiety-and-mental-toughness-in-female-collegiate-athletes
#11
Patrick B Wilson, Leilani A Madrigal
OBJECTIVE: Poor omega-3 fatty acid status has been linked to anxiety in the general population, but scarce data are available describing omega-3 fatty acid levels in athletes and their associations with anxiety and mental toughness. METHODS: Whole blood samples were obtained from 54 female collegiate athletes and analyzed for fatty acids as a part of this cross-sectional observational study. Participants also completed a food frequency questionnaire on the intake of omega-3 fatty acids, as well as the Beck Anxiety Inventory (BAI), Sport Anxiety Scale (SAS)-2, and Mental Toughness Scale (MTS)...
September 14, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28906299/integrated-plastic-surgery-residency-applicant-trends-and-comparison-with-other-surgical-specialties
#12
Jasson T Abraham, Anson V Nguyen, Robert A Weber
BACKGROUND: There has been a relatively rapid increase in the number and size of "integrated" residency programs in plastic surgery (PS) over the past decade. The objective of this study is to evaluate trends of US senior applicants of PS compared with other surgical specialties from 2007 to 2016. METHODS: Data were obtained from "NRMP: Main Residency Match" and from "NRMP: Charting Outcomes in the Match." Frequencies, percentages, and proportions were calculated for categorical variables...
September 12, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28901863/tissue-fatty-acid-profile-is-differently-modulated-from-olive-oil-and-omega-3-polyunsaturated-fatty-acids-in-apcmin-mice
#13
Valeria Tutino, Maria Gabriella Caruso, Giampiero De Leonardis, Valentina De Nunzio, Maria Notarnicola
BACKGROUND: Fatty acid profile can be consideredan appropriate biomarker for investigating the relations between the patterns of fatty acid metabolism and specific diseases, ascancer, cardiovascular and degenerative diseases. OBJECTIVE: Aim of this study was to test the effects of diets enriched with olive oil and omega-3Polyunsaturated Fatty Acids (PUFAs) on fatty acid profile in intestinal tissue of ApcMin/+ mice. METHOD: Three groups of animals were considered: control group, receiving a standard diet; olive oilgroup, receiving a standard diet enriched with olive oil; omega-3 group, receiving a standard diet enriched with salmon fish...
September 11, 2017: Endocrine, Metabolic & Immune Disorders Drug Targets
https://www.readbyqxmd.com/read/28901279/role-of-physical-exercise-and-omega-3-fatty-acids-on-depressive-illness-in-the-elderly
#14
Stefano Farioli-Vecchioli, Stefano Sacchetti, Vittoria Nicolis di Robilant, Debora Cutuli
BACKGROUND: In adulthood, depression is the most common type of mental illness and will be the second leading cause of disease by 2020. Major depression dramatically affects the function of the central nervous system and degrades life quality, especially during aging. Several mechanisms underlie the pathophysiology of depressive illness, given it has a multifactorial etiology. Human and animal studies have demonstrated that depression is mainly associated with imbalances in neurotransmitters and neurotrophins, hypothalamic-pituitary-adrenal axis alterations, brain volume changes, neurogenesis dysfunction, and dysregulation of inflammatory pathways...
September 11, 2017: Current Neuropharmacology
https://www.readbyqxmd.com/read/28900763/the-association-between-fatty-acid-index-and-in-vitro-fertilization-outcomes
#15
Ashley M Eskew, Kelly C Wormer, Michelle L Matthews, H James Norton, Margaret A Papadakis, Bradley S Hurst
PURPOSE: Fatty acids have been shown to play an important role in oocyte competence and early implantation of the embryo. Our hypothesis-generating study sought to determine if individual fatty acids expressed as a percentage of total erythrocyte fatty acids are associated with embryo quality and other in vitro fertilization (IVF) outcomes. METHODS: This was a prospective cohort study at an academic fertility center. Sixty women undergoing their first IVF cycle were recruited...
September 13, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28900407/psychometric-properties-of-a-multidimensional-scale-of-sense-of-community-in-the-school
#16
Gabriele Prati, Elvira Cicognani, Cinzia Albanesi
Sense of community in the school has been associated with a range of important outcomes for students. However, there are currently no standard definitions of sense of community in the school with corresponding measures with established psychometric properties. To fill this gap, the main aim of the present study was to propose a model of sense of community in the school, its operationalization and to examine its key psychometric properties (factorial structure, reliability, differential item functioning, differential test functioning of the scale and discriminant, convergent, and criterion validity)...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28900017/omega-3-fatty-acids-and-inflammatory-processes-from-molecules-to-man
#17
REVIEW
Philip C Calder
Inappropriate, excessive or uncontrolled inflammation contributes to a range of human diseases. Inflammation involves a multitude of cell types, chemical mediators and interactions. The present article will describe nutritional and metabolic aspects of omega-6 (n-6) and omega-3 (n-3) fatty acids and explain the roles of bioactive members of those fatty acid families in inflammatory processes. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are n-3 fatty acids found in oily fish and fish oil supplements...
September 12, 2017: Biochemical Society Transactions
https://www.readbyqxmd.com/read/28899773/hepatoprotective-effects-of-raspberry-rubus-coreanus-miq-seed-oil-and-its-major-constituents
#18
Hui Teng, Qiyang Lin, Kang Li, Benyao Yuan, Hongbo Song, Lunzhao Yi, Ming-Chi Wei, Yu-Chiao Yang, Maurizio Battino, Carlos L Cespedes Acuña, Lei Chen, Jianbo Xiao
Raspberry seed is a massive byproduct of raspberry juice and wine but usually discarded. The present study employed a microwave-assisted method for extraction of raspberry seed oil (RSO). The results revealed that omega-6 fatty acids (linoleic acid and γ-linolenic acid) were the major constituents in RSO. Cellular antioxidant enzyme activity such as superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT) were investigated in HepG2 cells treated with RSO. Induction of the synthesis of several antioxidants in H2O2-exposed HepG2 cells was found...
September 9, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28899766/health-relevance-of-the-modification-of-low-grade-inflammation-in-ageing-inflammageing-and-the-role-of-nutrition
#19
REVIEW
Philip C Calder, Nabil Bosco, Raphaëlle Bourdet-Sicard, Lucile Capuron, Nathalie Delzenne, Joel Doré, Claudio Franceschi, Markus J Lehtinen, Tobias Recker, Stefano Salvioli, Francesco Visioli
Ageing of the global population has become a public health concern with an important socio-economic dimension. Ageing is characterised by an increase in the concentration of inflammatory markers in the bloodstream, a phenomenon that has been termed "inflammageing". The inflammatory response is beneficial as an acute, transient reaction to harmful conditions, facilitating the defence, repair, turnover and adaptation of many tissues. However, chronic and low grade inflammation is likely to be detrimental for many tissues and for normal functions...
September 9, 2017: Ageing Research Reviews
https://www.readbyqxmd.com/read/28899612/the-schizotypal-personality-questionnaire-brief-lacks-measurement-invariance-across-three-countries
#20
Shujuan Liu, David Mellor, Mathew Ling, José L Saiz, Eugenia V Vinet, Xiaoyan Xu, Solomon Renati, Linda K Byrne
The Schizotypal Personality Questionnaire-Brief (SPQ-B) is a commonly-used tool for measuring schizotypal personality traits and due to its wide application, its cross-cultural validity is of interest. Previous studies suggest that the SPQ-B either has a three- or four-factor structure, but the majority of studies have been conducted in Western contexts and little is known about the psychometric properties of the scale in other populations. In this study factorial invariance testing across three cultural contexts-Australia, China and Chile was conducted...
September 6, 2017: Psychiatry Research
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