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https://www.readbyqxmd.com/read/28713397/fitness-outcomes-related-to-glyphosate-resistance-in-kochia-kochia-scoparia-what-life-history-stage-to-examine
#1
Omobolanle Adewale Osipitan, Johanna Anita Dille
A fast-spreading weed, kochia (Kochia scoparia), has developed resistance to the widely-used herbicide, glyphosate. Understanding the relationship between the occurrence of glyphosate resistance caused by multiple EPSPS gene copies and kochia fitness may suggest a more effective way of controlling kochia. A study was conducted to assess fitness cost of glyphosate resistance compared to susceptibility in kochia populations at different life history stages, that is rate of seed germination, increase in plant height, days to flowering, biomass accumulation at maturity, and fecundity...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28713043/auditory-discrimination-improvement-predicts-awakening-of-postanoxic-comatose-patients-treated-with-targeted-temperature-management-at-36%C3%A2-c
#2
Christian Pfeiffer, Nathalie Ata Nguepno Nguissi, Magali Chytiris, Phanie Bidlingmeyer, Matthias Haenggi, Rebekka Kurmann, Frédéric Zubler, Mauro Oddo, Andrea O Rossetti, Marzia De Lucia
BACKGROUND: Outcome prognostication in postanoxic comatose patients is more accurate in predicting poor than good recovery. Using electroencephalography recordings in patients treated with targeted temperature management at 33°C (TTM 33), we have previously shown that improvement in auditory discrimination over the first days of coma predicted awakening. Given the increased application of a 36°C temperature target (TTM 36), here we aimed at validating the predictive value of auditory discrimination in the TTM 36 setting...
July 13, 2017: Resuscitation
https://www.readbyqxmd.com/read/28711304/comparing-reach-chemical-safety-assessment-information-with-practice-a-case-study-of-polymethylmethacrylate-pmma-in-floor-coating-in-the-netherlands
#3
Ton Spee, Daan Huizer
On June 1st, 2007 the European regulation on Registration, Evaluation and Restriction of Chemical substances (REACH) came into force. Aim of the regulation is safe use of chemicals for humans and for the environment. The core element of REACH is chemical safety assessment of chemicals and communication of health and safety hazards and risk management measures throughout the supply chain. Extended Safety Data Sheets (Ext-SDS) are the primary carriers of health and safety information. The aim of our project was to find out whether the actual exposure to methyl methacrylate (MMA) during the application of polymethylmethacrylate (PMMA) in floor coatings as assessed in the chemical safety assessment, reflect the exposure situations as observed in the Dutch building practice...
June 4, 2017: International Journal of Hygiene and Environmental Health
https://www.readbyqxmd.com/read/28709953/association-of-hemodynamic-variables-with-in-hospital-mortality-and-favorable-neurological-outcomes-in-post-cardiac-arrest-care-with-targeted-temperature-management
#4
Chien-Hua Huang, Min-Shan Tsai, Hooi Nee Ong, Weiting Chen, Chih-Hung Wang, Wei-Tien Chang, Tzung-Dau Wang, Shyr-Chyr Chen, Matthew Huei-Ming Ma, Wen-Jone Chen
PURPOSE: Although hemodynamic instability is expected during the post-cardiac arrest period, the implications of hemodynamic parameters for outcomes remain unclear. Each phase of targeted temperature management (TTM) affects hemodynamic responses differently. This study aims to investigate the association of hemodynamic parameters with outcomes in patients receiving TTM after cardiac arrest. METHODS: The study prospectively enrolled patients who were treated with TTM (33°C for 24h) after cardiac arrest...
July 11, 2017: Resuscitation
https://www.readbyqxmd.com/read/28708684/the-impact-of-dysglycemia-and-glycemic-variability-on-targeted-temperature-management
#5
Yoshihiro Noji
No abstract text is available yet for this article.
August 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28708678/dysglycemia-glycemic-variability-and-outcome-after-cardiac-arrest-and-temperature-management-at-33%C3%A2-c-and-36%C3%A2-c
#6
Ola Borgquist, Matt P Wise, Niklas Nielsen, Nawaf Al-Subaie, Julius Cranshaw, Tobias Cronberg, Guy Glover, Christian Hassager, Jesper Kjaergaard, Michael Kuiper, Ondrej Smid, Andrew Walden, Hans Friberg
OBJECTIVES: Dysglycemia and glycemic variability are associated with poor outcomes in critically ill patients. Targeted temperature management alters blood glucose homeostasis. We investigated the association between blood glucose concentrations and glycemic variability and the neurologic outcomes of patients randomized to targeted temperature management at 33°C or 36°C after cardiac arrest. DESIGN: Post hoc analysis of the multicenter TTM-trial. Primary outcome of this analysis was neurologic outcome after 6 months, referred to as "Cerebral Performance Category...
August 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28708472/rectal-instillation-of-cold-fluids-for-targeted-temperature-management-after-cardiac-arrest-a-case-report
#7
Andrej Markota, Jure Fluher, Andreja Sinkovič
The optimal method of temperature management after cardiac arrest remains unknown. Methods that are most effective are usually invasive and expensive. Noninvasive methods are not as effective and obstruct access to the patient. Temperature management via rectal cooling offers some potential advantages in survivors of cardiac arrest, namely, relatively large volumes of temperature-controlled fluids can be instilled, access to the patient is not obstructed, and fluid overload can be ameliorated by removal of a fraction of instilled fluid...
July 14, 2017: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/28706860/targeted-temperature-management-in-neurological-intensive-care-unit
#8
REVIEW
Sombat Muengtaweepongsa, Winchana Srivilaithon
Targeted temperature management (TTM) shows the most promising neuroprotective therapy against hypoxic/ischemic encephalopathy (HIE). In addition, TTM is also useful for treatment of elevated intracranial pressure (ICP). HIE and elevated ICP are common catastrophic conditions in patients admitted in Neurologic intensive care unit (ICU). The most common cause of HIE is cardiac arrest. Randomized control trials demonstrate clinical benefits of TTM in patients with post-cardiac arrest. Although clinical benefit of ICP control by TTM in some specific critical condition, for an example in traumatic brain injury, is still controversial, efficacy of ICP control by TTM is confirmed by both in vivo and in vitro studies...
June 26, 2017: World Journal of Methodology
https://www.readbyqxmd.com/read/28700964/clinical-and-laboratory-predictors-of-infectious-complications-in-patients-after-out-of-hospital-cardiac-arrest
#9
Josef Kroupa, Jiri Knot, Jaroslav Ulman, Frantisek Bednar, Alena Dohnalova, Zuzana Motovska
PURPOSE: Identification of clinical and laboratory predictors related to Infectious Complications (ICs) in patients after Out-of-Hospital Cardiac Arrest (OHCA). METHODS: Patients, aged >18, after an OHCA between 9/2013 and 11/2015, surviving >24h, were studied. RESULTS: Study group consisted of 42 patients (mean age 63.4years, 88.1% men). Forty percent of patients had IC; lower respiratory tract infections were most common (87.5% of cases)...
July 4, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28698133/randomized-controlled-trial-of-internal-and-external-targeted-temperature-management-methods-in-post-cardiac-arrest-patients
#10
Xinqi Look, Huihua Li, Mingwei Ng, Eric Tien Siang Lim, Sohil Pothiawala, Kenneth Boon Kiat Tan, Duu Wen Sewa, Nur Shahidah, Pin Pin Pek, Marcus Eng Hock Ong
BACKGROUND: Targeted temperature management post-cardiac arrest is currently implemented using various methods, broadly categorized as internal and external. This study aimed to evaluate survival-to-hospital discharge and neurological outcomes (Glasgow-Pittsburgh Score) of post-cardiac arrest patients undergoing internal cooling verses external cooling. METHODOLOGY: A randomized controlled trial of post-resuscitation cardiac arrest patients was conducted from October 2008-September 2014...
July 5, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28695066/predicting-suitable-habitat-of-the-chinese-monal-lophophorus-lhuysii-using-ecological-niche-modeling-in-the-qionglai-mountains-china
#11
Bin Wang, Yu Xu, Jianghong Ran
Understanding the distribution and the extent of suitable habitats is crucial for wildlife conservation and management. Knowledge is limited regarding the natural habitats of the Chinese monal (Lophophorus lhuysii), which is a vulnerable Galliform species endemic to the high-montane areas of southwest China and a good candidate for being an umbrella species in the Qionglai Mountains. Using ecological niche modeling, we predicted current potential suitable habitats for the Chinese monal in the Qionglai Mountains with 64 presence points collected between 2005 and 2015...
2017: PeerJ
https://www.readbyqxmd.com/read/28693536/hypothermia-induced-alteration-of-repolarization-impact-on-acute-and-long-term-outcome-a-prospective-cohort-study
#12
Sophie von Ulmenstein, Christian Storm, Thomas G K Breuer, Sebastian Lask, Philipp Attanasio, Andreas Mügge, Alexander Wutzler
BACKGROUND: The effects of target temperature management (TTM) on the heart aren't thoroughly studied yet. Several studies showed the prolongation of various ECG parameters including Tpeak-Tend-time under TTM. Our study's goal is to evaluate the acute and long-term outcome of these prolongations. METHODS: In this study we included patients with successful resuscitation after cardiac arrest who were admitted to the Charité Virchow Klinikum Berlin or the Heart and Vascular Centre of the Ruhr University Bochum between February 2006 and July 2013 (Berlin) or May 2014 to November 2015 (Bochum)...
July 11, 2017: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
https://www.readbyqxmd.com/read/28688998/targeted-temperature-management-in-the-icu-guidelines-from-a-french-expert-panel
#13
Alain Cariou, Jean-Francois Payen, Karim Asehnoune, Gerard Audibert, Astrid Botte, Olivier Brissaud, Guillaume Debaty, Sandrine Deltour, Nicolas Deye, Nicolas Engrand, Gilles Francony, Stéphane Legriel, Bruno Levy, Philippe Meyer, Jean-Christophe Orban, Sylvain Renolleau, Bernard Vigue, Laure De Saint Blanquat, Cyrille Mathien, Lionel Velly
Over the recent period, the use of induced hypothermia has gained an increasing interest for critically ill patients, in particular in brain-injured patients. The term "targeted temperature management" (TTM) has now emerged as the most appropriate when referring to interventions used to reach and maintain a specific level temperature for each individual. TTM may be used to prevent fever, to maintain normothermia, or to lower core temperature. This treatment is widely used in intensive care units, mostly as a primary neuroprotective method...
July 5, 2017: Anaesthesia, Critical Care & Pain Medicine
https://www.readbyqxmd.com/read/28687281/head-computed-tomography-for-prognostication-of-poor-outcome-in-comatose-patients-after-cardiac-arrest-and-targeted-temperature-management
#14
Marion Moseby-Knappe, Tommaso Pellis, Irina Dragancea, Hans Friberg, Niklas Nielsen, Janneke Horn, Michael Kuiper, Andrea Roncarati, Roger Siemund, Johan Undén, Tobias Cronberg
INTRODUCTION: A multimodal approach to prognostication of outcome after cardiac arrest (CA) is recommended. Evidence for combinations of methods is low. In this post-hoc analysis we described findings on head computed tomography (CT) after CA. We also examined whether generalised oedema on CT alone or together with the biomarker Neuron-specific enolase (NSE) could predict poor outcome. METHODS: Patients participating in the Target Temperature Management after out-of-hospital-cardiac-arrest-trial underwent CT based on clinical indications...
July 4, 2017: Resuscitation
https://www.readbyqxmd.com/read/28687073/association-of-neuron-specific-enolase-values-with-outcomes-in-cardiac-arrest-survivors-is-dependent-on-the-time-of-sample-collection
#15
Dagmar Vondrakova, Andreas Kruger, Marek Janotka, Filip Malek, Vlasta Dudkova, Petr Neuzil, Petr Ostadal
BACKGROUND: Despite marked advances in intensive cardiology care, current options for outcome prediction in cardiac arrest survivors remain significantly limited. The aim of our study was, therefore, to compare the day-specific association of neuron-specific enolase (NSE) with outcomes in out-of-hospital cardiac arrest (OHCA) survivors treated with hypothermia. METHODS: Eligible patients were OHCA survivors treated with targeted temperature management at 33 °C for 24 h using an endovascular device...
July 8, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/28680434/unraveling-the-transcriptional-basis-of-temperature-dependent-pinoxaden-resistance-in-brachypodium-hybridum
#16
Maor Matzrafi, Lidor Shaar-Moshe, Baruch Rubin, Zvi Peleg
Climate change endangers food security and our ability to feed the ever-increasing human population. Weeds are the most important biotic stress, reducing crop-plant productivity worldwide. Chemical control, the main approach for weed management, can be strongly affected by temperature. Previously, we have shown that temperature-dependent non-target site (NTS) resistance of Brachypodium hybridum is due to enhanced detoxification of acetyl-CoA carboxylase inhibitors. Here, we explored the transcriptional basis of this phenomenon...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28668700/comparison-of-brain-computed-tomography-and-diffusion-weighted-magnetic-resonance-imaging-to-predict-early-neurologic-outcome-before-target-temperature-management-comatose-cardiac-arrest-survivors
#17
Chi Heon Jeon, Jung Soo Park, Ji Han Lee, Hoon Kim, Sang Chul Kim, Kyung Hye Park, Kyung Sik Yi, Sun Moon Kim, Chun Song Youn, Young-Min Kim, Byung Kook Lee
AIM: We previously reported that diffusion-weighted magnetic resonance imaging (DW-MRI) could be used to predict neurologic outcomes before targeted temperature management (TTM) after return of spontaneous circulation (ROSC) from cardiac arrest (CA). We compared the efficacy of brain computed tomography (CT) and DW-MRI to predict neurologic outcome before TTM in comatose cardiac arrest survivors. METHODS: We performed a retrospective study of CA patients treated with TTM...
June 28, 2017: Resuscitation
https://www.readbyqxmd.com/read/28655624/validity-of-the-iqcode-ca-an-informant-questionnaire-on-cognitive-decline-modified-for-a-cardiac-arrest-population
#18
Erik Blennow Nordström, Gisela Lilja, Kristofer Årestedt, Hans Friberg, Niklas Nielsen, Susanna Vestberg, Tobias Cronberg
AIM: To examine the psychometric properties of a modified version of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), for a cardiac arrest population (IQCODE-CA). METHODS: The IQCODE-CA, a 26-item observer-reported questionnaire, was completed by informants, defined as relatives or close friends, of 268 out-of-hospital cardiac arrest (OHCA) survivors who participated in the Target Temperature Management trial in a scheduled follow-up 180±14days after OHCA...
June 24, 2017: Resuscitation
https://www.readbyqxmd.com/read/28655424/risk-factors-for-early-return-visits-to-the-emergency-department-in-patients-with-urinary-tract-infection
#19
Sarah Jorgensen, Mira Zurayk, Samantha Yeung, Jill Terry, Maureen Dunn, Paul Nieberg, Annie Wong-Beringer
BACKGROUND: Optimal management of urinary tract infections (UTIs) in the emergency department (ED) is challenging due to high patient turnover, decreased continuity of care, and treatment decisions made in the absence of microbiologic data. We sought to identify risk factors for return visits in ED patients treated for UTI. METHODS: A random sample of 350 adult ED patients with UTI by ICD 9/10 codes was selected for review. Relevant data was extracted from medical charts and compared between patients with and without ED return visits within 30days (ERVs)...
June 21, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28652388/optimization-of-thermolytic-response-to-a1-adenosine-receptor-agonists-in-rats
#20
Isaac R Bailey, Bernard Laughlin, Lucille Moore, Lori K Bogren, Zeinab Barati, Kelly L Drew
Cardiac arrest is a leading cause of death in the United States and currently, therapeutic hypothermia, now called targeted temperature management (TTM), is the only recent treatment modality proven to increase survival rates and reduce morbidity for this condition. Shivering and subsequent metabolic stress, however, limits application and benefit of TTM. Stimulating CNS A1 adenosine receptors inhibits shivering and non-shivering thermogenesis in rats and induces a hibernation-like response in hibernating species...
June 26, 2017: Journal of Pharmacology and Experimental Therapeutics
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