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https://www.readbyqxmd.com/read/28550709/effect-of-renal-function-status-on-the-prognostic-value-of-heart-rate-in-acute-ischemic-stroke-patients
#1
Zhengbao Zhu, Chongke Zhong, Tian Xu, Aili Wang, Yanbo Peng, Tan Xu, Hao Peng, Chung-Shiuan Chen, Jinchao Wang, Zhong Ju, Qunwei Li, Deqin Geng, Yingxian Sun, Qingjuan Du, Yongqiu Li, Jing Chen, Yonghong Zhang, Jiang He
BACKGROUND AND AIMS: The association between heart rate and prognosis of ischemic stroke remains debatable, and whether renal function status influences the relationship between them is still not elucidated. METHODS: A total of 3923 ischemic stroke patients were included in this prospective multicenter study from the China Antihypertensive Trial in Acute Ischemic Stroke (CATIS). The primary outcome was a combination of death and major disability (modified Rankin Scale score ≥3) at 3 months after stroke...
May 19, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28549500/greater-preclinical-atherosclerosis-in-treated-monogenic-familial-hypercholesterolemia-vs-polygenic-hypercholesterolemia
#2
Mahtab Sharifi, Elizabeth Higginson, Sven Bos, Angela Gallivan, Darren Harvey, Ka Wah Li, Amali Abeysekera, Angela Haddon, Helen Ashby, Kate E Shipman, Jackie A Cooper, Marta Futema, Jeanine E Roeters van Lennep, Eric J G Sijbrands, Mourad Labib, Devaki Nair, Steve E Humphries
BACKGROUND AND AIMS: Familial hypercholesterolemia (FH) is a common inherited disorder of low density lipoprotein-cholesterol (LDL-C) metabolism. It is associated with higher risk of premature coronary heart disease. Around 60% of patients with a clinical diagnosis of FH do not have a detectable mutation in the genes causing FH and are most likely to have a polygenic cause for their raised LDL-C. We assessed the degree of preclinical atherosclerosis in treated patients with monogenic FH versus polygenic hypercholesterolemia...
May 13, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28549428/rheumatoid-factors-do-not-predict-cardiovascular-disease-and-mortality-in-the-general-population-in-the-busselton-health-survey
#3
Johannes Nossent, Warren Raymond, Mark Divitini, Matthew Knuiman
BACKGROUND: Rheumatoid Factors (RF) are antibodies directed against the Fc portion of IgG and are involved in clearance of immune complexes. While RF can develop in a wide range of conditions, higher RF levels indicate a greater risk for a severe disease course in Rheumatoid Arthritis (RA) patients including cardiovascular complications and premature death. We investigated whether RF also constitute a risk factor for these outcomes in the general population. METHODS: We included 2,323 participants (46% male, mean age 50 years) free of CVD at baseline in 1972...
May 26, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28549245/analysis-of-heart-rate-variability-and-risk-factors-for-sudep-in-patients-with-drug-resistant-epilepsy
#4
Leyla Baysal-Kirac, Nail Güven Serbest, Erdi Şahin, Hava Özlem Dede, Candan Gürses, Ayşen Gökyiğit, Nerses Bebek, Ahmet Kaya Bilge, Betül Baykan
BACKGROUND: Cardiac problems have been suggested as causes of sudden unexpected death in epilepsy (SUDEP). Our aim was to investigate possible associations of cardiac autonomic functions based on heart rate variability (HRV) parameters with risk factors of SUDEP in patients with drug-resistant epilepsy. METHODS: Forty-seven patients with drug-resistant seizures and 45 healthy control subjects were enrolled in the study. Interictal time domain parameters of HRV were evaluated with 24-hour Holter recordings...
May 23, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28549113/restrictive-enlargement-of-the-pulmonary-annulus-at-repair-of-tetralogy-of-fallot-a-comparative-10-year-follow-up-study%C3%A2
#5
Jana Logoteta, Lars Dullin, Jan Hinnerk Hansen, Carsten Rickers, Mona Salehi Ravesh, Abdullah Al Bulushi, Ines Kristo, Philip Wegner, Michael Schumacher, Tim Attmann, Jens Scheewe, Hans-Heiner Kramer
OBJECTIVES: Since 1996, our centre performs restrictive enlargement of the pulmonary annulus at surgical repair of tetralogy of Fallot. A transannular patch is only used if the z-score of the pulmonary annulus is smaller than -2. We sought to determine whether this strategy reduces pulmonary insufficiency (PI) and reoperation rate compared to a nationwide contemporary cohort that has not been operated using a uniform strategy. METHODS: Eighty-seven tetralogy of Fallot patients were included in the study (Group 1)...
May 26, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28549083/a-comparison-of-two-mouse-frailty-assessment-tools
#6
Alice E Kane, Aniko Huizer-Pajkos, John Mach, Sarah J Mitchell, Rafael de Cabo, David G Le Couteur, Susan E Howlett, Sarah N Hilmer
The mouse clinical frailty index and the mouse frailty phenotype assessment are two recently developed tools used to assess frailty in mice. The objectives of this study were to investigate whether the same mice are identified as frail with both tools and to examine the association of each of the assessment tools with age and frailty-related outcomes. Frailty was measured using both tools in old (~24 months; n = 36) C57BL/6 male mice. After 2 weeks, blood pressure and heart rate were measured and serum samples were collected for analysis of alanine aminotransferase, creatinine, and albumin levels...
May 26, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28548564/eating-habits-and-food-additive-intakes-are-associated-with-emotional-states-based-on-eeg-and-hrv-in-healthy-korean-children-and-adolescents
#7
Jin Young Kim, Hye Lim Kang, Dae-Keun Kim, Seung Wan Kang, Yoo Kyoung Park
PURPOSE: Recent study suggests that psychological issues and eating habits are closely related. In this study, we aimed to find the association between eating habits and intakes of artificial sweeteners with emotional states of schoolchildren using quantitatively analyzing objective biosignals. METHODS: The study was conducted at the National Standard Reference Data Center for Korean EEG as a cross-sectional study. Three hundred eighteen healthy children who have not been diagnosed with neurologic or psychiatric disorders were evaluated (168 girls and 150 boys; mean age of 11...
May 26, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28548185/-evaluation-the-american-college-of-cardiology-and-american-heart-association-predictive-score-for-cardiovascular-diseases
#8
Mónica Acevedo, Giovanna Valentino, Verónica Kramer, María José Bustamante, Marcela Adasme, Lorena Orellana, Fernando Baraona, Carlos Navarrete
BACKGROUND: Recently, the American College of Cardiology and American Heart Association (ACC/AHA) proposed a new cardiovascular risk (CV) score. AIM: To evaluate the new risk score (ACC/AHA 2013) in a Chilean population. MATERIAL AND METHODS: Between 2002 and 2014, body mass index (BMI), waist circumference, blood pressure, lipid profile and fasting blood glucose levels were measured and a survey about CV risk factors was responded by 3,284 subjects aged 40 to 79 years (38% females), living in urban Santiago...
March 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28547923/pediatric-heart-disease-simulation-curriculum-educating-the-pediatrician
#9
Tyler H Harris, Mark Adler, Sharon M Unti, Mary E McBride
BACKGROUND: Training guidelines state that pediatricians should be able to diagnose, manage, and triage patients with heart disease. Acutely ill cardiac patients present infrequently and with high acuity, yet residents receive less exposure to acute cardiac conditions than previous generations. Trainees must learn to manage these situations despite this gap. Simulation has been used successfully to train learners to provide acute care. We hypothesized that a simulation-based cardiac curriculum would improve residents' ability to manage cardiac patients...
May 26, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28547176/metabolic-volume-performs-better-than-suvmax-in-the-detection-of-left-ventricular-assist-device-driveline-infection
#10
Nemanja Avramovic, Angelo Maria Dell'Aquila, Matthias Weckesser, Danka Milankovic, Alexis Vrachimis, Jürgen R Sindermann, Christian Wenning
PURPOSE: A continuous-flow left ventricular assist device (LVAD) is a new and highly promising therapy in supporting end-stage heart failure patients, either bridging them to heart transplantation or as a destination therapy. Infection is one of the major complications associated with LVAD implants. (18)F-FDG PET/CT has already been shown to be useful in the detection of LVAD infection. The goal of this study was to compare the diagnostic accuracy of different PET analysis techniques (visual grading versus SUVmax and metabolic volume)...
May 25, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28546848/estimation-of-maximal-oxygen-consumption-and-heart-rate-recovery-using-the-tecumseh-sub-maximal-step-test-and-their-relationship-to-cardiovascular-risk-factors
#11
Alun D Hughes, Nish Chaturvedi
BACKGROUND: Maximum aerobic capacity (VO2max) is associated with lower cardiovascular and total mortality. Step tests can be used to provide an estimate of (VO2max) in epidemiological or home-based studies. We compared different methods of estimation of VO2max and heart rate recovery and evaluated the relationship of these estimates with cardiovascular risk factors. METHODS: Data were analysed from 2286 participants in the Tecumseh Community Health Study (>16y and <70y) who performed a step test...
June 2017: Artery Research
https://www.readbyqxmd.com/read/28546529/the-safety-of-electrical-cardioversion-under-the-control-of-transesophageal-echocardiography-in-patients-with-atrial-fibrillation-and-inadequate-anticoagulation
#12
Joanna Zaprutko, Artur Baszko, Michał Michalak, Karol Kochman, Radosław Szymański, Jan Kłopocki, Anna Nowicka, Rafał Dankowski, Marek Michalski, Piotr Kałmucki, Andrzej Szyszka
INTRODUCTION    Restoring sinus rhythm in patients with atrial fibrillation (AF)/atrial flutter (AF) requires adequate oral anticoagulation (OAC) prior to direct current cardioversion (DCC). Some patients eligible for DCC are not properly anticoagulated. OBJECTIVES    Assessment of risk factors for thrombus and spontaneous echo contrast (SEC) in the left atrium (LA) as well as the safety profile of DCC under transesophageal echocardiography control (TEE) in patients with inadequate anticoagulation. PATIENTS AND METHODS    From the cohort of 316 patients admitted for DCC, 139 (age 63...
May 25, 2017: Polish Archives of Internal Medicine
https://www.readbyqxmd.com/read/28546285/anti-inflammatory-effects-and-mechanisms-of-vagal-nerve-stimulation-combined-with-electroacupuncture-in-a-rodent-model-of-tnbs-induced-colitis
#13
Haifeng Jin, Jie Guo, Jiemin Liu, Bin Lyu, Robert D Foreman, Jieyun Yin, Zhaohong Shi, Jiande Dz Chen
The purpose of this study was to determine effects and mechanisms of vagal nerve stimulation (VNS) and additive effects of electroacupuncture (EA) on colonic inflammation in a rodent model of IBD. Chronic inflammation in rats was induced by intrarectal TNBS (2,4,6-Trinitrobenzenesulfonic acid). The rats were then treated with sham-ES (electrical stimulation), VNS or VNS+EA for 3 weeks. Inflammatory responses were assessed by disease activity index (DAI), macroscopic scores and histological scores of colonic tissues, and plasma levels of TNF-α, IL-1β and IL-6, myeloperoxidase (MPO) activity of colonic tissues...
May 25, 2017: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/28545873/reveal-linq-versus-reveal-xt-implantable-loop-recorders-intra-and-post-procedural-comparison
#14
Hoang H Nguyen, Ian H Law, Michael W Rudokas, Jennifer Lampe, Tammy M Bowman, George F Van Hare, Jennifer N Avari Silva
OBJECTIVES: To compare the procedure, recovery, hospitalization times, and costs along with patient/parent satisfaction after newer-generation cardiac implantable loop recorder (Reveal LINQ; Medtronic Inc, Minneapolis, Minnesota) and previous-generation implantable loop recorder (Reveal XT; Medtronic Inc). STUDY DESIGN: A prospective study of patients undergoing LINQ implantations between April 2014 and October 2015 was performed. Retrospective chart review of patients undergoing XT implantations was performed for comparison...
May 22, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28544396/current-trends-in-racial-ethnic-and-healthcare-disparities-associated-with-pediatric-cardiac-surgery-outcomes
#15
Jennifer K Peterson, Yanjun Chen, Danh V Nguyen, Shaun P Setty
OBJECTIVE: Despite overall improvements in congenital heart disease outcomes, racial and ethnic disparities have continued. The purpose of this study is to examine the effect of race and ethnicity, as well as other risk factors on congenital heart surgery length of stay and in-hospital mortality. DESIGN: From the 2012 Healthcare Cost and Utilization Project Kids Inpatient Database (KID), we identified 13 130 records with Risk Adjustment in Congenital Heart Surgery complexity score-eligible procedures...
May 22, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28543953/improved-technical-success-postnatal-outcomes-and-refined-predictors-of-outcome-for-fetal-aortic-valvuloplasty
#16
Kevin G Friedman, Lynn A Sleeper, Lindsay R Freud, Audrey C Marshall, Max E Godfrey, Monika Drogosz, Terra Lafranchi, Carol B Benson, Louise E Wilkins-Haug, Wayne Tworetzky
BACKGROUND: Fetal aortic valvuloplasty (FAV) may prevent progression of mid-gestation aortic stenosis (AS) to hypoplastic left heart syndrome (HLHS). METHODS: We evaluate outcomes in 123 fetuses that underwent FAV between 2000 and 2015. We analyze whether technical success and biventricular (Biv) outcome changed from the early era (2000-08) to a more recent era (2009-15) and identify pre-FAV predictors of Biv outcome. We developed CART models to predict the likelihood of Biv outcome...
May 22, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28542926/effect-of-spironolactone-on-exercise-tolerance-and-arterial-function-in-older-adults-with-heart-failure-with-preserved-ejection-fraction
#17
Bharathi Upadhya, William G Hundley, Peter H Brubaker, Timothy M Morgan, Kathryn P Stewart, Dalane W Kitzman
OBJECTIVES: To evaluate the effects of an aldosterone antagonist on exercise intolerance in older adults with heart failure and preserved ejection fraction (HFpEF). DESIGN: Randomized, placebo-controlled, double-blind trial. SETTING: Academic medical center, Winston-Salem, North Carolina. PARTICIPANTS: Older adults (N = 80, aged 71 ± 1; 80% female) with stable compensated HFpEF and controlled blood pressure (BP)...
May 19, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28541595/how-does-ivabradine-effect-erectile-dysfunction-in-patients-with-heart-failure
#18
Fatih Aydın, Serkan Bektur, Yasin Taşdelen, Yüksel Kıvrak, Ayşe Hüseyinoglu Aydın
BACKGROUND AND AIM: Erectile dysfunction (ED) is the inability or insufficiensy of penile erection that causes dissatisfaction during sexual intercourse. ED is seen in patients with heart failure (HF) ranging from %56-81 depending on the severity. Patients usually blame their cardiovascular medications for their ED. Ivabradine is used for antianginal effects and to improve exercise intolerance and decrease mortality in patients with HF. Most beta-blockers are known to cause ED but unlike beta-blockers the effect of ivabradine over ED has never been evaluated...
May 25, 2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28541588/effects-of-low-intensity-exercise-in-older-adults-with-chronic-heart-failure-during-the-transitional-period-from-hospital-to-home-in-china-a-randomized-controlled-trial
#19
Li Xueyu, Yu Hao, Xu Shunlin, Li Rongbin, Gao Yuan
The transitional period from hospital to home is critical to decreasing rates of preventable, poor post-discharge outcomes. Older adults with chronic heart failure (CHF) may be challenged to exercise during the transitional period. The purpose of the current study was to test the effects of low-intensity exercise on health-related quality of life (HRQoL), physical function, and heart function in Chinese older adults with CHF during the transitional period. The study was randomized, single-blinded, and controlled...
May 1, 2017: Research in Gerontological Nursing
https://www.readbyqxmd.com/read/28540933/the-effect-of-high-altitude-on-central-blood-pressure-and-arterial-stiffness
#20
C J Boos, E Vincent, A Mellor, D R Woods, C New, R Cruttenden, M Barlow, M Cooke, K Deighton, P Scott, S Clarke, J O'Hara
Central arterial systolic blood pressure (SBP) and arterial stiffness are known to be better predictors of adverse cardiovascular outcomes than brachial SBP. The effect of progressive high altitude (HA) on these parameters has not been examined. Ninety healthy adults were included. Central BP and the augmentation index (AI) were measured at the level of the brachial artery (Uscom BP(+) device) at <200 m and at 3619, 4600 and 5140 m. The average age of the subjects (70% men) were 32.2±8.7 years. Compared with central arterial pressures, brachial SBP (+8...
May 25, 2017: Journal of Human Hypertension
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