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https://www.readbyqxmd.com/read/29211364/insights-into-novel-anticancer-applications-for-apigenin
#1
REVIEW
Adam Kowalczyk, Agnieszka Bodalska, Marta Miranowicz, Katarzyna Karłowicz-Bodalska
Flavonoids, naturally occuring derivatives of 2-phenyl-benzo-γ-pyrone, are widespread in plants as coloring substances. Apigenin (4',5,7,-trihydroxyflavone (5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one), molecular formula C₁₅H₁₀O⁵, is a flavonoid present in many fruits and vegetables, primarily in citrus fruits, apples, parsley and celery leaves. It is also found in some medicinal plants, including chamomile flowers, thyme, oregano, peppermint, lemon balm and yarrow, as a 7-O-glycoside with anti-inflammatory and antioxidant activity...
October 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29210169/electrospun-nanofibers-comprising-of-silk-fibroin-gelatin-for-drug-delivery-applications-thyme-essential-oil-and-doxycycline-monohydrate-release-study
#2
Masoud Dadras Chomachayi, Atefeh Solouk, Somaye Akbari, Davoud Sadeghi, Fereshteh Mirahmadi, Hamid Mirzadeh
In this study, a nanofibrous electrospun substrate based on the silk fibroin (SF) and gelatin (GT) polymers were prepared and evaluated. The SF/GT blended solutions were prepared with various ratios of GT in formic acid and electrospun to obtain bead-free fibers. Results showed that addition of GT to SF increased nanofiber's diameter, bulk hydrophilicity, surface wettability, mass loss percentage, but decreased Young's modulus, tensile strength, and porosity of the SF/GT mats. According to the obtained results, the mat containing 10% of GT was selected as the optimized mat for further studies and loaded with thyme essential oil (TEO) and doxycycline monohydrate (DCMH) as the antibacterial agents...
December 6, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/29196013/the-potential-of-herbs-and-spices-to-reduce-lipid-oxidation-during-heating-and-gastrointestinal-digestion-of-a-beef-product
#3
T Van Hecke, P L Ho, S Goethals, S De Smet
Here we tested the potential of ten culinary herbs (basil, oregano, rosemary and thyme) and spices (black pepper, cayenne pepper, cumin, curcuma, garlic and sweet paprika) to limit oxidation during cooking of a high-fat beef product, and during its subsequent in vitro gastrointestinal digestion. The herbs and spices were added separately at 0.5% and 1% (w/w), either during meat processing before heating of the product or after heating of the meat as a seasoning. Lipid oxidation was evaluated by malondialdehyde, 4-hydroxy-2-nonenal and hexanal quantification in the meat products and gastrointestinal digests...
December 2017: Food Research International
https://www.readbyqxmd.com/read/29191726/essential-oils-of-culinary-herbs-and-spices-display-agonist-and-antagonist-activities-at-human-aryl-hydrocarbon-receptor-ahr
#4
Iveta Bartoňková, Zdeněk Dvořák
Essential oils (EOs) of culinary herbs and spices are used to flavor, color and preserve foods and drinks. Dietary intake of EOs is significant, deserving an attention of toxicologists. We examined the effects of 31 EOs of culinary herbs and spices on the transcriptional activity of human aryl hydrocarbon receptor (AhR), which is a pivotal xenobiotic sensor, having also multiple roles in human physiology. Tested EOs were sorted out into AhR-inactive ones (14 EOs) and AhR-active ones, including full agonists (cumin, jasmine, vanilla, bay leaf), partial agonists (cloves, dill, thyme, nutmeg, oregano) and antagonists (tarragon, caraway, turmeric, lovage, fennel, spearmint, star anise, anise)...
November 27, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29189053/person-centred-communication-for-emotional-support-in-district-nursing-sage-and-thyme-model
#5
Jane Griffiths
Patients on district nursing caseloads have multiple physical morbidities, and related emotional concerns. District nurses are ideally placed to assess and meet patients' emotional needs but in increasingly stretched workplaces, it is difficult to find time. There is also evidence that district nurses sometimes believe they lack skills to address patients' concerns. Traditional communication skills training is useful for encouraging patients to open up about their concerns, but less helpful at finding workable solutions...
December 2, 2017: British Journal of Community Nursing
https://www.readbyqxmd.com/read/29183758/evaluation-of-intrinsic-and-acquired-immune-cells-infiltration-in-kidney-and-spleen-of-the-mice-infected-with-systemic-candidiasis-and-treated-with-chloroform-fraction-of-zataria-multiflora-boiss
#6
Mansour Bayat, Niloofar Hassannejad, Hadi Ghazanfari
BACKGROUND AND AIMS: Despite the use of antifungal drugs, the visceral candidiasis is associated with a high mortality rate. The aims of this study were an evaluation of intrinsic and acquired immune cells infiltration in kidney and spleen of the mice infected with systemic candidiasis and treated with chloroform fraction of Zataria Multiflora Boiss. MATERIALS AND METHODS: Candida albicans (C. albicans) ATCC10231 clinical standard strain was isolated. C. albicans LD50 was determined...
November 25, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29175783/total-antioxidant-capacity-of-commonly-used-fruits-vegetables-herbs-and-spices-of-pakistan
#7
Mobasher Ali Abid, Muhammad Ashfaq, Muhammad Junaid Hassan Sharif, Khalid Rauf, Wajahat Mahmood, Ikarmullah Khan, Ghulam Abbas
The current study was aimed at investigating the total antioxidant activity (TAC) of various fruits, vegetables, herbs and spices habitat in Pakistan. The ferric reducing ability of plasma (FRAP) assay was used to measure the TAC of various extracts (aqueous, ethanolic and aqueous-ethanolic). Following is the potency order for fruits (guava >strawberry >Pomegranate >apple >kinnow >melon >lemon >banana), vegetables (spinach >Cabbage (Purple) >Jalapeno >Radish >Brinjal >Bell Pepper >Lettuce >Carrot >Cabbage (White) >Onion >Potato >Tomato >Cucumber) and herbs/spices (clove >Rosemary >Thyme >Oregano >Cinnamon >Cumin >Kalonji >Paprika >Neem (Flower) >Fennel >Black Cardamom >Turmeric >Coriander >Ginger >Garlic)...
November 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29175764/the-effect-of-essential-oils-on-microbial-composition-and-quality-of-grass-carp-ctenopharyngodon-idellus-fillets-during-chilled-storage
#8
Zhan Huang, Xiaochang Liu, Shiliang Jia, Longteng Zhang, Yongkang Luo
Antimicrobial and antioxidant effects of essential oils (oregano, thyme, and star anise) on microbial composition and quality of grass carp fillets were investigated. Essential oils treatment was found to be effective in inhibiting microbial growth, delaying lipid oxidation, and retarding the increase of TVB-N, putrescine, hypoxanthine, and K-value. Based on sensory analysis, shelf-life of grass carp fillets was 6days for control and 8days for treatment groups. Among the essential oils, oregano essential oil exhibited the highest antimicrobial and antioxidant activities...
November 6, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/29169731/a-composition-of-medicinal-plants-with-an-enhanced-ability-to-suppress-microsomal-lipid-peroxidation-and-a-protective-activity-against-carbon-tetrachloride-induced-hepatotoxicity
#9
Araylim N Aralbaeva, Aigul T Mamataeva, Nazgul I Zhaparkulova, Raisa S Utegalieva, Marina Khanin, Michael Danilenko, Maira K Murzakhmetova
Treatment of liver injury induced by various toxicants represents a serious clinical challenge. Here, we utilized the ability of natural agents to inhibit microsomal lipid peroxidation (LPO) as the in-vitro screening paradigm for selecting efficacious tissue-protective combinations of cooperatively acting medicinal plants. Based on screening of 70 water-ethanol extracts obtained from different parts of 65 plants we prepared a highly active phytocomposition (PC-1) containing oregano (Origanum vulgare), wild thyme (Thymus serpyllum) and coltsfoot (Tussilago farfara) aerial parts, valerian (Valeriana officinalis) leaves and little-leaf linden (Tilia cordata) flowers...
November 20, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29166272/in-vitro-activity-of-some-essential-oils-alone-and-in-combination-against-the-fish-pathogen-nocardia-seriolae
#10
T F Ismail, T Yoshida
Microplate resazurin assay was applied to investigate the in vitro activity of four essential oils (EOs); cinnamon (Cinnamomum zeylanicum), thyme (Thymus vulgaris), lemongrass (Cymbopogon flexuosus) and tea tree (Melaleuca alternifolia) oils against 80 clinical isolates of the fish pathogen Nocardia seriolae. The checkerboard test was then used to determine the possible synergistic effect of EOs combination against reference type strains of fish nocardiosis. All tested EOs had antibacterial activity against N...
September 26, 2017: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/29163441/antifungal-and-anti-biofilm-activity-of-essential-oil-active-components-against-cryptococcus-neoformans-and-cryptococcus-laurentii
#11
Poonam Kumari, Rutusmita Mishra, Neha Arora, Apurva Chatrath, Rashmi Gangwar, Partha Roy, Ramasare Prasad
Cryptococcosis is an emerging and recalcitrant systemic infection occurring in immunocompromised patients. This invasive fungal infection is difficult to treat due to the ability of Cryptococcus neoformans and Cryptococcus laurentii to form biofilms resistant to standard antifungal treatment. The toxicity concern of these drugs has stimulated the search for natural therapeutic alternatives. Essential oil and their active components (EO-ACs) have shown to possess the variety of biological and pharmacological properties...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29129385/effect-directed-fingerprints-of-77-botanical-extracts-via-a-generic-high-performance-thin-layer-chromatography-method-combined-with-assays-and-mass-spectrometry
#12
S Krüger, L Hüsken, R Fornasari, I Scainelli, G E Morlock
Quantitative effect-directed profiles of 77 industrially and freshly extracted botanicals like herbs, spices, vegetables and fruits, widely used as food ingredients, dietary supplements or traditional medicine, gave relevant information on their quality. It allows the assessment of food, dietary supplements and phytomedicines with regard to potential health-promoting activities. In contrary to sum parameter assays and targeted analysis, chromatography combined with effect-directed analysis allows fast assignment of single active compounds and evaluation of their contribution to the overall activity, originating from a food or botanical sample...
October 29, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29127810/antimicrobial-activities-of-gaseous-essential-oils-against-listeria-monocytogenes-on-a-laboratory-medium-and-radish-sprouts
#13
Gyeongmin Lee, Yoonbin Kim, Hoikyung Kim, Larry R Beuchat, Jee-Hoon Ryu
The aim of this study was to evaluate the antimicrobial activities of gaseous essential oils (EO gases) against Listeria monocytogenes on the surfaces of a laboratory medium and radish sprouts. We determined the minimal inhibitory concentration (MIC) and minimal lethal concentration (MLC) values of EO gases from eight EOs extracted from basil leaves, carrot seed, cinnamon bark, cinnamon leaves, clove flower buds, oregano leaves, thyme flowers (linalool), and thyme leaves (thymol) against L. monocytogenes on a nutrient agar supplemented with 1% glucose and 0...
November 4, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/29125992/phenol-enriched-olive-oils-improve-hdl-antioxidant-content-in-hypercholesterolemic-subjects-a-randomized-double-blind-cross-over-controlled-trial
#14
Marta Farràs, Sara Fernández-Castillejo, Laura Rubió, Sara Arranz, Úrsula Catalán, Isaac Subirana, Mari-Paz Romero, Olga Castañer, Anna Pedret, Gemma Blanchart, Daniel Muñoz-Aguayo, Helmut Schröder, Maria-Isabel Covas, Rafael de la Torre, Maria-José Motilva, Rosa Solà, Montserrat Fitó
At present, high-density lipoprotein (HDL) function is thought to be more relevant than HDL cholesterol quantity. Consumption of olive oil phenolic compounds (PCs) has beneficial effects on HDL-related markers. Enriched food with complementary antioxidants could be a suitable option to obtain additional protective effects. Our aim was to ascertain whether virgin olive oils (VOOs) enriched with (a) their own PC (FVOO) and (b) their own PC plus complementary ones from thyme (FVOOT) could improve HDL status and function...
September 28, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/29105634/essential-oils-showing-in-vitro-anti-mrsa-and-synergistic-activity-with-penicillin-group-of-antibiotics
#15
Bushra Uzair, Naheed Niaz, Asma Bano, Barkat Ali Khan, Naheed Zafar, Muhammad Iqbal, Riffat Tahira, Fehmida Fasim
This study was planned in order to investigate effective essential oils to inhibit in-vitro growth of Methicillin resistant Staphylococcus aureus (MRSA). In this study using disc diffusion method anti MRSA activity of ten diverse essential oils extracted from traditional plants namely Thymus vulgaris L, Mentha pulegium, Ocimum sanctum, Mentha piperita, Cymbopogon citratus, Rosmarinus officinalis L., Cortex cinnamom, Citrus nobilis x Citrus deliciosa, Origanum vulgare and Mentha sp. was examined. All the essential oils inhibited growth of S...
September 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29104267/acaricidal-activity-and-synergistic-effect-of-thyme-oil-constituents-against-carmine-spider-mite-tetranychus-cinnabarinus-boisduval
#16
Lipeng Wu, Xin Huo, Xiaolong Zhou, Duoyong Zhao, Weizhong He, Shenghong Liu, Hejiang Liu, Ting Feng, Cheng Wang
Studies examining the use of essential oils as replacements for synthetic insecticides require an understanding of the contribution of each constituent present, interactions among these components, and how they relate to overall toxicity. In the present study, the chemical composition of commercial thyme oil was identified by gas chromatography-mass spectrometry. Thyme oil and blends of its major constituents were tested for their acaricidal activitities against carmine spider mites (Tetranychus cinnabarinus (Boisduval)) using a slide-dip bioassay...
November 1, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29098578/antifungal-activity-of-essential-oils-on-two-venturia-inaequalis-strains-with-different-sensitivities-to-tebuconazole
#17
Jérôme Muchembled, Caroline Deweer, Karin Sahmer, Patrice Halama
The antifungal activity of seven essential oils (eucalyptus, clove, mint, oregano, savory, tea tree, and thyme) was studied on Venturia inaequalis, the fungus responsible for apple scab. The composition of the essential oils was checked by gas chromatography-mass spectrometry. Each essential oil had its main compound. Liquid tests were performed to calculate the IC50 of essential oils as well as their majority compounds. The tests were made on two strains with different sensitivities to tebuconazole: S755, the sensitive strain, and rs552, the strain with reduced sensitivity...
November 2, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29083491/the-determination-of-the-botanical-origin-in-honeys-with-over-represented-pollen-combination-of-melissopalynological-sensory-and-physicochemical-analysis
#18
M Rodopoulou, C Tananaki, M Dimou, V Liolios, D Kanelis, G Goras, A Thrasyvoulou
BACKGROUND: Pollen analysis of honey is the basic method for the determination of its botanical origin. However, the presence of over-represented pollen in honeys may lead the analysis to false results. This can be more severe if this pollen is present in unifloral under-represented honeys of commercial importance, for instance thyme honey. In this study, we investigated the abundance of over-represented pollen grains on several quality characteristics in honey samples. In particular, we mixed honeys characterised as over-represented, specifically chestnut and eucalyptus, with thyme honeys in different analogies; and we analysed the melissopalynological, organoleptic, physicochemical (water content, electrical conductivity, colour) and volatile characteristics of the blends...
October 30, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29077554/antifungal-properties-of-essential-oils-for-improvement-of-indoor-air-quality-a-review
#19
REVIEW
Harriet Whiley, Sharyn Gaskin, Tiffany Schroder, Kirstin Ross
Concerns regarding indoor air quality, particularly the presence of fungi and moulds, are increasing. The potential for essential oils to reduce, control or remove fungi, is gaining interest as they are seen as a "natural" alternative to synthetic chemical fungicides. This review examines published research on essential oils as a method of fungal control in indoor environments. It was difficult to compare the relative performances of essential oils due to differences in research methods and reporting languages...
October 27, 2017: Reviews on Environmental Health
https://www.readbyqxmd.com/read/29026857/repellency-effect-of-essential-oils-of-some-native-plants-and-synthetic-repellents-against-human-flea-pulex-irritans-siphonaptera-pulicidae
#20
Mohammad Bagher Ghavami, Fahimeh Poorrastgoo, Behrooz Taghiloo, Jamshid Mohammadi
BACKGROUND: Fleas are important vectors of human and animal disease, and control measures for protection against their bites and flea-borne diseases are necessary. METHODS: The essential oils (EOs) of four native medicinal plants, Ziziphora tenuiore, Myrtus communis, Achillea wilhelmsii and Mentha piperita were isolated by hydrodistillation technique and analyzed by GC-MC. The repellent activity of EOs and synthetic compounds, DEET and permethrin, were assayed on human subjects against field collected fleas...
March 2017: Journal of Arthropod-borne Diseases
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