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toledano and britton

M Toledano, J W Britton, A McKeon, C Shin, V A Lennon, A M L Quek, E So, G A Worrell, G D Cascino, C J Klein, T D Lagerlund, E C Wirrell, K C Nickels, S J Pittock
OBJECTIVE: To evaluate a trial of immunotherapy as an aid to diagnosis in suspected autoimmune epilepsy. METHOD: We reviewed the charts of 110 patients seen at our autoimmune neurology clinic with seizures as a chief complaint. Twenty-nine patients met the following inclusion criteria: (1) autoimmune epilepsy suspected based on the presence of ≥ 1 neural autoantibody (n = 23), personal or family history or physical stigmata of autoimmunity, and frequent or medically intractable seizures; and (2) initiated a 6- to 12-week trial of IV methylprednisolone (IVMP), IV immune globulin (IVIg), or both...
May 6, 2014: Neurology
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